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Endocrinology, ISSN 0013-7227, 09/2013, Volume 154, Issue 9, pp. 3410 - 3422
We recently created a mouse model displaying precocious Sertoli cell (SC) and spermatogenic development induced by SC-specific transgenic androgen receptor... 
MOUSE TESTIS | IMMATURE HYPOPHYSECTOMIZED RATS | TESTICULAR AROMATASE-ACTIVITY | DEPENDENT EXPRESSION | ESTROGEN SULFOTRANSFERASE | TESTOSTERONE SECRETION | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | FOLLICLE-STIMULATING-HORMONE | POSTNATAL-DEVELOPMENT | LUTEINIZING-HORMONE | Leydig Cells - cytology | Up-Regulation | Receptors, Transforming Growth Factor beta - genetics | Testis - metabolism | Cell Count | Receptors, Androgen - metabolism | Male | Receptors, Peptide - genetics | Isoenzymes - metabolism | Leydig Cells - metabolism | Receptors, Androgen - biosynthesis | Sertoli Cells - cytology | Sexual Development | Cell Differentiation | Receptors, Cell Surface - biosynthesis | Patched Receptors | Receptor, Platelet-Derived Growth Factor alpha - biosynthesis | Animals, Newborn | Biomarkers - metabolism | Sertoli Cells - metabolism | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Testis - cytology | Testosterone Congeners - blood | Isoenzymes - genetics | Receptors, Cell Surface - metabolism | Mice, Transgenic | Receptors, Peptide - biosynthesis | Testis - growth & development | Hemizygote | Receptors, Transforming Growth Factor beta - biosynthesis | Animals | Receptors, Androgen - genetics | Receptors, Transforming Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor alpha - genetics | Testosterone Congeners - metabolism | Ligands | Mice | Isoenzymes - biosynthesis | Patched-1 Receptor | Receptors, Cell Surface - genetics | Receptors, Peptide - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Developmental Biology, ISSN 0012-1606, 04/2016, Volume 412, Issue 2, pp. 278 - 287
The hedgehog family includes Sonic hedgehog (Shh), Desert hedgehog, and Indian hedgehog, which are well known as a morphogens that play many important roles... 
Branching morphogenesis | EGF receptor | Epithelio-mesenchymal interaction | Salivary gland | Shh | EGF | PATHWAYS | CELLS | ECTODYSPLASIN | MECHANISMS | DEVELOPMENTAL BIOLOGY | FACTOR RECEPTOR | IN-VITRO | EPIDERMAL-GROWTH-FACTOR | EPITHELIAL MORPHOGENESIS | GENE-EXPRESSION | Receptor, Epidermal Growth Factor - genetics | Hedgehog Proteins - pharmacology | Receptor, ErbB-3 - metabolism | Receptor, ErbB-2 - genetics | ErbB Receptors - genetics | Receptor, ErbB-2 - metabolism | Receptor, Epidermal Growth Factor - metabolism | Hedgehog Proteins - genetics | Female | Patched Receptors | Phosphorylation - drug effects | Organ Culture Techniques | ErbB Receptors - metabolism | Epidermal Growth Factor - genetics | Gene Expression Regulation, Developmental - drug effects | Submandibular Gland - metabolism | Receptors, Cell Surface - metabolism | Epidermal Growth Factor - metabolism | Receptor, ErbB-3 - genetics | Recombinant Proteins - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Inbred ICR | Pregnancy | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Morphogenesis - drug effects | Submandibular Gland - embryology | Patched-1 Receptor | Mitogen-Activated Protein Kinase 1 - metabolism | Receptors, Cell Surface - genetics | RNA | Epidermal growth factor | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2018, Volume 13, Issue 12, pp. e0208221 - e0208221
The aim of this study was to investigate the prognostic value of the Hedgehog (Gli, Patched1, Shh, Smo) and Notch (Jag1, Notch2, Notch3) pathway members, in... 
SOLID TUMORS | SIGNALING PATHWAY | MICROSATELLITE INSTABILITY | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | RECEPTOR | ADJUVANT THERAPY | PTCH | EXPRESSION | CARCINOMA | STAGE-II | Jagged-1 Protein - metabolism | Prognosis | Receptors, Notch - metabolism | Humans | Middle Aged | Endometrial Neoplasms - metabolism | Hedgehog Proteins - metabolism | Receptor, Notch2 - genetics | Receptors, Notch - genetics | DNA Mismatch Repair - genetics | Patched-1 Receptor - genetics | Patched-1 Receptor - metabolism | DNA Mismatch Repair - physiology | Endometrial Neoplasms - genetics | Hedgehog Proteins - genetics | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Receptor, Notch3 - genetics | Receptor, Notch3 - metabolism | Receptor, Notch2 - metabolism | Signal Transduction - genetics | Jagged-1 Protein - genetics | Endometrial Neoplasms - pathology | Signal Transduction - physiology | Aged | Biomarkers, Tumor - genetics | Cluster Analysis | Immunohistochemistry | Care and treatment | Cancer patients | Endometrial cancer | Analysis | Diagnosis | Tumor proteins | Cancer | Cluster analysis | Health sciences | Yeast | Laboratories | Pathogenesis | p53 Protein | Risk | Oncology | Systematic review | Clinical outcomes | Proteins | Pathways | Mismatch repair | Endometrium | Deoxyribonucleic acid--DNA | Medical research | Mortality | Gynecology | Risk reduction | Histology | Gene expression | Clustering | Patients | Obstetrics | ErbB-2 protein | Patched protein | Medicine | Pathology | Hospitals | Hedgehog protein | Medical prognosis | Ligands | Mutation | PTEN protein | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Development (Cambridge, England), ISSN 0950-1991, 2014, Volume 141, Issue 17, pp. 3331 - 3339
Journal Article
Developmental Biology, ISSN 0012-1606, 07/2014, Volume 391, Issue 2, pp. 219 - 229
Journal Article
Open Engineering, ISSN 1932-6203, 02/2018, Volume 13, Issue 10, pp. 349 - 353
Objective Dysregulation of the Hedgehog (Hh) pathway has been described in a variety of cancers, including cervical cancer, a disease which shares a common... 
PATHWAY ACTIVATION | PREDICTS | SIGNALING MOLECULES | DRUG-RESISTANCE | GENE | MULTIDISCIPLINARY SCIENCES | Vulvar Lichen Sclerosus - metabolism | Neoplasm Recurrence, Local - metabolism | Vulvar Lichen Sclerosus - complications | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Patched-1 Receptor - genetics | Vulvar Lichen Sclerosus - pathology | Neoplasm Recurrence, Local - pathology | Patched-1 Receptor - metabolism | Vulvar Lichen Sclerosus - genetics | Vulvar Neoplasms - pathology | Vulvar Neoplasms - complications | Vulvar Neoplasms - genetics | Carcinoma, Squamous Cell - complications | Vulvar Neoplasms - metabolism | Aged, 80 and over | Female | Neoplasm Recurrence, Local - genetics | Aged | Sonic hedgehog | Care and treatment | Relapse | Vulvar cancer | Genetic aspects | Research | Gene expression | Risk factors | Cancer | Immunohistochemistry | Squamous cell carcinoma | Development and progression | Cervical cancer | Diseases | Medical research | Gynecology | Health risks | Risk | Histology | Vulva | Cervix | Drug resistance | Epithelium | Patients | Clinical outcomes | Signal transduction | Human papillomavirus | Statistical models | Hedgehog protein | Medical prognosis | Biomarkers | Bioindicators | Mathematical models | Index Medicus
Journal Article