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Genetics, ISSN 0016-6731, 03/2016, Volume 202, Issue 3, pp. 1105 - 1118
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0181366
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 2, p. e14680
Background: Hedgehog (Hh) signaling is crucial for the generation and maintenance of both embryonic and adult stem cells, thereby regulating development and... 
NEURAL STEM-CELLS | ASYMMETRIC INHERITANCE | RADIAL GLIAL-CELLS | CORTICAL-NEURONS | ADULT BRAIN | IN-VIVO | BIOLOGY | RESTRICTED PROGENITORS | CENTRAL-NERVOUS-SYSTEM | DIFFERENTIATION | CEREBRAL-CORTEX | Nestin | Neocortex - embryology | Embryo, Mammalian | Receptors, Notch - metabolism | Hedgehog Proteins - metabolism | Receptors, Notch - genetics | Hedgehog Proteins - physiology | Neurogenesis - genetics | Neocortex - metabolism | Hedgehog Proteins - genetics | Female | Receptors, Cell Surface - physiology | Patched Receptors | Cell Division - genetics | Cells, Cultured | Neural Stem Cells - physiology | Receptors, Notch - physiology | Mice, Transgenic | Signal Transduction - genetics | Body Patterning - physiology | Cell Division - physiology | Nerve Tissue Proteins - metabolism | Pregnancy | Animals | Neurogenesis - physiology | Neocortex - cytology | Signal Transduction - physiology | Mice | Body Patterning - genetics | Intermediate Filament Proteins - metabolism | Neural Stem Cells - metabolism | Patched-1 Receptor | Receptors, Cell Surface - genetics | Brain | Neurons | Intermediate filament proteins | Stem cells | Cell proliferation | Transcription | Embryo cells | Radial glial cells | Homeostasis | Nervous system | Glial cells | Inactivation | Neurogenesis | Neuronal-glial interactions | Signal transduction | Embryogenesis | Pathways | Clonal deletion | Rodents | Cell cycle | Deletion | Divisions | Ventricular zone | Dopamine | Deactivation | Cortex | Signaling | Lamination | Hedgehog protein | Cells (biology) | Neural stem cells | Notch protein | Ventricle | Cancer
Journal Article
Developmental Biology, ISSN 0012-1606, 07/2014, Volume 391, Issue 2, pp. 219 - 229
Journal Article
Development, ISSN 0950-1991, 06/2008, Volume 135, Issue 11, pp. 1947 - 1956
Chondrocyte hypertrophy is an essential process required for endochondral bone formation. Proper regulation of chondrocyte hypertrophy is also required in... 
Ihh | Patched 1 | Cartilage | Chondrocyte hypertrophy | PTHrP | PATHWAYS | OSTEOBLAST | cartilage | chondrocyte hypertrophy | PROLIFERATION | DEVELOPMENTAL BIOLOGY | CARTILAGE DEVELOPMENT | ENDOCHONDRAL BONE | SKELETON | patched 1 | HORMONE-RELATED-PROTEIN | GROWTH-PLATE | DIFFERENTIATION | Immunohistochemistry | Hedgehog Proteins - pharmacology | Bone Morphogenetic Proteins - physiology | Hedgehog Proteins - metabolism | Hedgehog Proteins - physiology | Wnt Proteins - metabolism | Cell Differentiation - genetics | Bone Morphogenetic Proteins - metabolism | In Situ Hybridization | Wnt Proteins - genetics | Hedgehog Proteins - genetics | Receptors, Cell Surface - physiology | beta Catenin - physiology | Patched Receptors | Bone Morphogenetic Proteins - genetics | Cell Differentiation - physiology | Chondrocytes - metabolism | Organ Culture Techniques | Recombinant Proteins - metabolism | Chondrocytes - pathology | Parathyroid Hormone-Related Protein - genetics | Cells, Cultured | Receptors, Cell Surface - metabolism | Signal Transduction - genetics | Cell Enlargement | Recombinant Proteins - pharmacology | Forelimb - metabolism | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | beta Catenin - genetics | Animals | Signal Transduction - drug effects | Parathyroid Hormone-Related Protein - physiology | Signal Transduction - physiology | Forelimb - cytology | Mice | Wnt Proteins - physiology | Mutation | Patched-1 Receptor | Receptors, Cell Surface - genetics
Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 02/2012, Volume 22, Issue 2, pp. 268 - 278
Journal Article
Glia, ISSN 0894-1491, 05/2012, Volume 60, Issue 6, pp. 851 - 866
Oligodendrocyte precursor cells (OPCs) of the optic nerve are generated in the preoptic area, from where they migrate to colonize it entirely. Sonic hedgehog... 
Ptc‐1 | internalization | LRP2 | Gli1 | optic nerve | astrocyte | Optic nerve | Astrocyte | Internalization | Ptc-1 | PROGENITOR CELLS | TRANSCRIPTION FACTORS | FACTOR OLEIC-ACID | SPECIFICATION | ASTROCYTES | NEUROSCIENCES | AUTOIMMUNE ENCEPHALOMYELITIS | ORIGIN | MULTIPLE-SCLEROSIS | EXTRACELLULAR-MATRIX | RAT OPTIC-NERVE | Optic Nerve - cytology | Cytarabine - pharmacology | Cricetulus | Low Density Lipoprotein Receptor-Related Protein-2 - physiology | Embryo, Mammalian | Vimentin - metabolism | Hedgehog Proteins - metabolism | Green Fluorescent Proteins - genetics | Glial Fibrillary Acidic Protein - metabolism | Exocytosis - physiology | Cell Movement - physiology | Eye - embryology | Chemotaxis - physiology | Oligodendroglia - drug effects | Oligodendroglia - physiology | Transfection | Hedgehog Proteins - genetics | Kruppel-Like Transcription Factors - metabolism | Gangliosides - metabolism | Myelin Proteolipid Protein - metabolism | Fibroblast Growth Factor 2 - metabolism | Optic Nerve - embryology | Bromodeoxyuridine - metabolism | Patched Receptors | Immunosuppressive Agents - pharmacology | Gene Expression Regulation, Developmental - physiology | Eye - metabolism | Green Fluorescent Proteins - metabolism | Cricetinae | Cells, Cultured | Receptors, Cell Surface - metabolism | Low Density Lipoprotein Receptor-Related Protein-2 - metabolism | Coculture Techniques - methods | Embryonic Stem Cells - physiology | Antibodies - pharmacology | Cell Movement - drug effects | Astrocytes - physiology | Animals | Embryonic Stem Cells - drug effects | Low Density Lipoprotein Receptor-Related Protein-2 - immunology | Cell Proliferation - drug effects | Mice | Zinc Finger Protein GLI1 | Patched-1 Receptor
Journal Article
Development, ISSN 0950-1991, 09/2006, Volume 133, Issue 18, pp. 3695 - 3707
Both the Wnt/beta-catenin and Ihh signaling pathways play essential roles in crucial aspects of endochondral ossification: osteoblast differentiation,... 
β-catenin | Cartilage | Chondrocyte hypertrophy | Ihh | Endochondral bone | Joint | Wnt | Patched | Osteoblast differentiation | beta-catenin | PATHWAYS | OSTEOBLAST | joint | PROTEIN | cartilage | chondrocyte hypertrophy | endochondral bone | PROLIFERATION | DEVELOPMENTAL BIOLOGY | CHONDROCYTE DIFFERENTIATION | SKELETON | osteoblast differentiation | patched | INDIAN-HEDGEHOG | PTH/PTHRP RECEPTOR | GROWTH-PLATE | Immunohistochemistry | Cell Cycle - genetics | Chondrocytes - cytology | Osteogenesis - physiology | Cell Proliferation | Cell Survival - genetics | Apoptosis - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Wnt Proteins - metabolism | Hedgehog Proteins | Cell Differentiation - genetics | In Situ Hybridization | Gene Expression Regulation, Developmental | Bone and Bones - metabolism | Cartilage - cytology | Receptors, Cell Surface - physiology | Osteoblasts - cytology | Patched Receptors | Cell Differentiation - physiology | Cell Survival - physiology | Chondrocytes - metabolism | Joints - metabolism | Osteogenesis - genetics | Bone and Bones - cytology | Cartilage - embryology | Receptors, Cell Surface - metabolism | In Situ Nick-End Labeling - methods | Signal Transduction - genetics | Cartilage - metabolism | Wnt Proteins - chemistry | beta Catenin - metabolism | beta Catenin - genetics | Chondrocytes - enzymology | Animals | Joints - embryology | Joints - cytology | Cell Cycle - physiology | Signal Transduction - physiology | Mice | Apoptosis - physiology | Bone and Bones - embryology | Osteoblasts - metabolism | Patched-1 Receptor | Receptors, Cell Surface - genetics
Journal Article
Oncogene, ISSN 0950-9232, 09/2007, Volume 26, Issue 44, pp. 6442 - 6447
Journal Article