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Journal Article
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 01/2019, Volume 68, Issue 1, pp. 56 - 63
Journal Article
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 09/2019, Volume 129, pp. 118 - 129
Journal Article
2014, ISBN 9780124017306
Neural crest cells (NCC) emerge from the neural plate border between the neural plate and non-neural ectoderm as the neural tube closes. These cells migrate... 
Induced pluripotent stem cells | Patient-derived cells | Neural crest | Disease model | Neurocristopathies
Book Chapter
Cancer Research, ISSN 0008-5472, 10/2017, Volume 77, Issue 20, pp. 5491 - 5502
Journal Article
2013, ISBN 0124158943
The first years of the 21 century have seen an unparalleled progress in biomedical sciences. Several dogmata that haunted scientific debate for decades were... 
Patient-derived primary cells | Disease models | Ex vivo organ models | Induced pluripotent stem cells | Animal use alternatives | Analytical tools | Human-on-a-chip | Organotypic models | 3D cell culture | Non-invasive imaging | Microfluidics | Embryonic stem cell test
Book Chapter
WORLD JOURNAL OF STEM CELLS, ISSN 1948-0210, 06/2015, Volume 7, Issue 5, pp. 823 - 838
Pathogenic mutations involving DNA repeat expansions are responsible for over 20 different neuronal and neuromuscular diseases. All result from expanded tracts... 
Human embryonic stem cells | Repeat somatic instability | repeat-associated non-ATG translation | RNA toxicity | Disease modeling | Epigenetics | Unstable repeat associated disorders | Patient-derived induced pluripotent stem cells | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Review
Journal Article
世界干细胞杂志:英文版(电子版), ISSN 1948-0210, 2015, Issue 5, pp. 823 - 838
Pathogenic mutations involving DNA repeat expansionsare responsible for over 20 different neuronal andneuromuscular diseases. All result from expanded tractsof... 
disorders;Human | Patient-derived | modeling | Disease | RNA | Unstable | non-ATG | Epigenetics;repeat-associated | embryonic | cells | repeat | associated | instability | translation | somatic | inducedpluripotent | stem | toxicity;Repeat
Journal Article
GENES, ISSN 2073-4425, 10/2016, Volume 7, Issue 10, p. 77
Journal Article
Stem Cells and Development, ISSN 1547-3287, 07/2018, Volume 27, Issue 14, pp. 96 - 967
Leucine-rich repeat kinase 2 (LRRK2) G2019S (glycine to serine) is the most common mutation associated with sporadic and familial Parkinson's disease (PD) with... 
Comprehensive Reviews | LRRK2 G2019S | patient-derived cells | kinase inhibitors | Parkinson's disease | MEDICINE, RESEARCH & EXPERIMENTAL | LOCALIZATION | LRRK2 | ALPHA-SYNUCLEIN | AUTOPHAGY | MITOCHONDRIAL-DNA | GTP-BINDING | CELL & TISSUE ENGINEERING | TRANSPLANTATION | PENETRANCE | INHIBITION | GENE | MUTATIONS | HEMATOLOGY
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2019, Volume 517, Issue 1, pp. 49 - 56
Patient-derived xenografts (PDXs) are widely recognised as a more physiologically relevant preclinical model than standard cell lines, but are expensive and... 
Conditional reprogramming | Drug discovery | Patient derived xenograft | Bladder cancer | Cell line models | TRANSFORMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CISPLATIN RESISTANCE | CULTURE | PLURIPOTENT STEM-CELLS | IN-VITRO | BIOPHYSICS | EPITHELIAL-CELLS | INHIBITOR | IMMORTALIZATION | REPROGRAMMED CELLS | XENOGRAFTS | Medical colleges | Analysis | Index Medicus
Journal Article
Cancer Letters, ISSN 0304-3835, 08/2019, Volume 457, pp. 20 - 27
Journal Article