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Developmental Cell, ISSN 1534-5807, 2005, Volume 8, Issue 2, pp. 167 - 178
FGF, WNT, and BMP signaling promote neural crest formation at the neural plate boundary in vertebrate embryos. To understand how these signals are integrated,... 
MORPHOGENESIS | C-RET | INHIBITION | POSTERIOR NONAXIAL MESODERM | SPINAL-CORD | MECHANISMS | DEVELOPMENTAL BIOLOGY | SPECIFICATION | PLATE | HOMEOBOX GENE | EXPRESSION | CELL BIOLOGY | Oligodeoxyribonucleotides, Antisense - pharmacology | Xenopus Proteins - genetics | Fibroblast Growth Factors - genetics | Oligodeoxyribonucleotides, Antisense - genetics | Wnt Proteins | MSX1 Transcription Factor | Intercellular Signaling Peptides and Proteins - physiology | Base Sequence | Xenopus laevis - genetics | Fibroblast Growth Factors - physiology | Embryonic Induction - genetics | DNA-Binding Proteins - physiology | PAX3 Transcription Factor | Transcription Factors - physiology | Xenopus laevis - embryology | Signal Transduction | Paired Box Transcription Factors | Intercellular Signaling Peptides and Proteins - genetics | Embryonic Induction - physiology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | Models, Biological | Neural Crest - embryology | Xenopus Proteins - physiology | Xenopus laevis - physiology | Homeodomain Proteins - physiology | Fibroblast Growth Factor 8 | Xenopus laevis | Intercellular Signaling Peptides and Proteins | Neurons and Cognition | Psychology and behavior | Neurobiology | Embryonic Induction | Xenopus Proteins | Neural Crest | Life Sciences | Homeodomain Proteins | Cognitive Sciences | Transcription Factors | Fibroblast Growth Factors | Oligodeoxyribonucleotides, Antisense | DNA-Binding Proteins
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e20309
Yes-associated protein 65 (YAP) contains multiple protein-protein interaction domains and functions as both a transcriptional co-activator and as a scaffolding... 
CREST | WW DOMAIN | CRANIAL PLACODES | XENOPUS-EMBRYOS | GENE | LAEVIS | MULTIDISCIPLINARY SCIENCES | ENHANCER | HOMOLOG | INDUCTION | TRANSCRIPTION FACTOR | Paired Box Transcription Factors - genetics | Xenopus Proteins - genetics | Humans | Molecular Sequence Data | Neural Plate - cytology | Neural Stem Cells - cytology | Trans-Activators - chemistry | Neural Crest - metabolism | Xenopus Proteins - chemistry | DNA-Binding Proteins - metabolism | Gene Expression Regulation, Developmental | Base Sequence | Trans-Activators - genetics | Conserved Sequence | Cell Differentiation | Binding Sites | Biomarkers - metabolism | Protein Structure, Tertiary | Neural Crest - cytology | PAX3 Transcription Factor | Gastrulation | Zebrafish Proteins - metabolism | Xenopus laevis | Nuclear Proteins - metabolism | Zebrafish | Axis, Cervical Vertebra - growth & development | Protein Transport | Transcription Factors - metabolism | Animals | Neural Plate - embryology | Epidermal Cells | Axis, Cervical Vertebra - metabolism | Trans-Activators - metabolism | Xenopus Proteins - metabolism | Neural Stem Cells - metabolism | Paired Box Transcription Factors - metabolism | Muscles - cytology | Embryonic development | Gene expression | Genes | Protein-protein interactions | Heart | Phosphorylation | Transcription factors | Ectoderm | Transcription | Biology | Kinases | Neurogenesis | Defects | Proteins | Cell growth | Animal tissues | Neural plate | Pax3 protein | Inhibition | Elongation | Yolk | Phenotypes | Nutrient deficiency | Hatching | Muscles | Epidermis | RNA polymerase | Embryos | Amphibians | Neural crest | Yes-associated protein | Yolk sac | Scaffolding | Plates (structural members) | Neural stem cells | Laboratory animals | Protein interaction | Binding sites | Structure-function relationships
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2017, Volume 130, Issue 21, pp. 3685 - 3697
Journal Article
Science, ISSN 0036-8075, 9/2005, Volume 309, Issue 5743, pp. 2064 - 2067
Muscle satellite cells contribute to muscle regeneration. We have used a mouse line to directly isolate (Pax3)(green fluorescent protein)-expressing muscle... 
Skeletal muscle satellite cells | Cytometry | Artificial satellites | B lymphocytes | Muscles | Cultured cells | Reports | Progenitor cells | Cells | Skeletal muscle | Tissue grafting | STEM-CELLS | MYOGENESIS | MULTIDISCIPLINARY SCIENCES | M-CADHERIN | QUIESCENT | MYOBLAST TRANSPLANTATION | FATE | EXPRESSION | CD34 | MDX MICE | Antigens, CD34 - analysis | Dystrophin - biosynthesis | PAX7 Transcription Factor | DNA-Binding Proteins - analysis | Muscle Fibers, Skeletal - metabolism | Muscle, Skeletal - cytology | Stem Cell Transplantation | Muscle Development | Flow Cytometry | Mice, Inbred mdx | Satellite Cells, Skeletal Muscle - physiology | PAX3 Transcription Factor | Green Fluorescent Proteins - analysis | Homeodomain Proteins - biosynthesis | Cell Separation | Paired Box Transcription Factors | Satellite Cells, Skeletal Muscle - cytology | Cells, Cultured | Transcription Factors - biosynthesis | Muscle, Skeletal - physiology | Regeneration | Satellite Cells, Skeletal Muscle - transplantation | Animals | Homeodomain Proteins - analysis | Mice, Nude | Mice | Transcription Factors - analysis | Diaphragm | DNA-Binding Proteins - biosynthesis | Research | Analysis | Proteins | Cell culture | Muscular system | Rodents | Antigens, CD34 | Green Fluorescent Proteins | Muscle Fibers | Homeodomain Proteins | Transcription Factors | Muscle, Skeletal | Dystrophin | Satellite Cells, Skeletal Muscle | DNA-Binding Proteins
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/1999, Volume 18, Issue 13, pp. 3702 - 3711
The Pax3–FKHR fusion protein is present in alveolar rhabdomyosarcoma and results from the t(2;13) (q35;q14) chromosomal translocation. Its oncogenic activity... 
Pax3 | Pax3–FKHR | hDaxx | rhabdomyosarcomas | transcriptional regulation | Rhabdomyosarcomas | Pax3-FKHR | Transcriptional regulation | COMPLEX | ACTIVATION | DAXX | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-COR | TRANSCRIPTIONAL REPRESSION | BINDING PROTEIN | CELL BIOLOGY | ALVEOLAR RHABDOMYOSARCOMA | SIN3 | HISTONE DEACETYLASE | Sequence Deletion | Oncogene Proteins, Fusion - metabolism | Phosphorylation | Molecular Weight | Humans | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | DNA-Binding Proteins - metabolism | Oncogene Proteins, Fusion - chemistry | Transfection | Cloning, Molecular | Repressor Proteins - isolation & purification | Carrier Proteins - chemistry | Repressor Proteins - metabolism | Amino Acid Sequence | Cell Line | PAX3 Transcription Factor | Repressor Proteins - chemistry | Paired Box Transcription Factors | Intracellular Signaling Peptides and Proteins | Repressor Proteins - genetics | DNA - metabolism | DNA-Binding Proteins - chemistry | Precipitin Tests | Nuclear Proteins | DNA - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Yeasts - genetics | Adaptor Proteins, Signal Transducing | Carrier Proteins - metabolism | Carrier Proteins - isolation & purification | Protein Binding | Forkhead Box Protein O1 | Rhabdomyosarcoma - genetics | Forkhead Transcription Factors | Translocation, Genetic - genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e20815
The enteric nervous system (ENS) regulates peristaltic movement of the gut, and abnormal ENS causes Hirschsprung's disease (HSCR) in newborns. HSCR is a... 
RNA-POLYMERASE-II | C-RET | 2.1 PROTEIN | ENTERIC NERVOUS-SYSTEM | CORE PROMOTER | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | STEM-CELL | PROTOONCOGENE PROMOTER | HIRSCHSPRUNGS-DISEASE | MUTATIONS | Promoter Regions, Genetic | RNA, Small Interfering - genetics | Thyroid Nuclear Factor 1 | Proto-Oncogene Proteins c-ret - metabolism | Homeodomain Proteins - metabolism | Humans | Hirschsprung Disease - genetics | Molecular Sequence Data | Nuclear Proteins - metabolism | Transcription Factors - genetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Phenotype | Animals | Gene Expression Regulation, Developmental | Base Sequence | Cell Line, Tumor | Transcription, Genetic | Enteric Nervous System - physiology | Nuclear Proteins - genetics | Binding Sites | Hirschsprung Disease - metabolism | Proto-Oncogene Proteins c-ret - genetics | RNA, Small Interfering - metabolism | Tyrosine | Genetic disorders | Genetic transcription | DNA binding proteins | Genes | Haplotypes | Neonates | Transcription factors | Nervous system | Activation | Thyroid gland | Single-nucleotide polymorphism | Kinases | Proteins | Enteric nervous system | Ret protein | Intestine | Transgenic animals | Surgery | Protein-tyrosine kinase receptors | Pax3 protein | Phox2b protein | Protein-tyrosine kinase | Phenotypes | Human motion | Gene expression | Sox10 protein | Ganglia | Hirschsprung's disease | Medicine | Thyroid transcription factor 1 | Binding sites
Journal Article
Genes and Development, ISSN 0890-9369, 02/1998, Volume 12, Issue 3, pp. 290 - 303
Previous work has indicated that signals from the neural tube, notochord, and surface ectoderm promote somitic myogenesis. Here, we show that somitic... 
Noggin | Pax3 | Somitic myogenesis | BMP | Myf5 | QUAIL EMBRYOS | BETA FAMILY | SONIC HEDGEHOG | somitic myogenesis | NEURAL-TUBE | DEVELOPMENTAL BIOLOGY | BHLH GENE-EXPRESSION | PARAXIAL MESODERM | MUSCLE DIFFERENTIATION | FLOOR PLATE | GENETICS & HEREDITY | BONE MORPHOGENETIC PROTEIN-4 | PAX-3 EXPRESSION | Body Patterning - drug effects | Bone Morphogenetic Proteins - antagonists & inhibitors | Bone Morphogenetic Proteins - physiology | Mitogens - pharmacology | MyoD Protein - genetics | Wnt Proteins | Ectoderm - physiology | Hedgehog Proteins | Time Factors | Bone Morphogenetic Proteins - pharmacology | Muscle Proteins - physiology | Carrier Proteins | DNA-Binding Proteins - physiology | Signal Transduction | Paired Box Transcription Factors | Muscles - embryology | Myogenic Regulatory Factor 5 | Chick Embryo | Muscle Proteins - genetics | Muscles - drug effects | Transcription Factors | COS Cells | MyoD Protein - drug effects | Wnt1 Protein | Somites - cytology | Gene Expression Regulation, Developmental | Mitogens - physiology | CHO Cells | Proto-Oncogene Proteins - pharmacology | Somites - metabolism | Proteins - physiology | Cricetinae | PAX3 Transcription Factor | Bone Morphogenetic Protein 4 | Muscles - physiology | Trans-Activators | DNA-Binding Proteins - drug effects | Zebrafish Proteins | Embryonic Induction - physiology | Muscle Proteins - drug effects | DNA-Binding Proteins - genetics | Body Patterning - physiology | Proteins - genetics | Animals | Proto-Oncogene Proteins - physiology | Mesoderm - physiology | Proteins - pharmacology | Embryonic Induction - drug effects | MyoD Protein - physiology | Cell cycle | Somite | Genetic aspects | Regulation | Research | Genetic transcription | Gene expression | Genetic translation | Myogenesis | Research Paper
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 07/2015, Volume 6, Issue 1, p. 7557
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in childhood. Here we studied 60 RMSs using whole-exome/-transcriptome sequencing, copy number... 
WIDE DNA METHYLATION | AMPLIFICATION | PIK3CA GENE | EMBRYONAL RHABDOMYOSARCOMA | PATHWAY MUTATIONS | ADOLESCENTS | MULTIDISCIPLINARY SCIENCES | PTEN | ALVEOLAR RHABDOMYOSARCOMA | HUMAN CANCER | BREAST | Paired Box Transcription Factors - genetics | F-Box-WD Repeat-Containing Protein 7 | ras Proteins - genetics | Prognosis | Rhabdomyosarcoma, Embryonal - classification | Humans | Transcriptome | Child, Preschool | PAX7 Transcription Factor - genetics | Infant | Male | Rhabdomyosarcoma, Alveolar - classification | RNA, Messenger - metabolism | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Exome | Rhabdomyosarcoma, Embryonal - genetics | Young Adult | Cell Cycle Proteins - genetics | Female | Receptor, Fibroblast Growth Factor, Type 4 - genetics | Child | Gene Expression Regulation, Neoplastic - genetics | PTEN Phosphohydrolase - genetics | PAX3 Transcription Factor | Rhabdomyosarcoma, Alveolar - genetics | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | DNA Methylation - genetics | Forkhead Transcription Factors - genetics | beta Catenin - genetics | Epigenesis, Genetic - genetics | Adolescent | Rhabdomyosarcoma - classification | Forkhead Box Protein O1 | Rhabdomyosarcoma - genetics | Mutation | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics
Journal Article
Stem Cells, ISSN 1066-5099, 11/2009, Volume 27, Issue 11, pp. 2769 - 2780
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e39642
Muscle satellite cells make up a stem cell population that is capable of differentiating into myocytes and contributing to muscle regeneration upon injury. In... 
SKELETAL-MUSCLE | STEM-CELLS | IN-VITRO | AXIAL SKELETON | MYOGENIC DIFFERENTIATION | MULTIDISCIPLINARY SCIENCES | FRACTURE REPAIR | BONE-MARROW | SATELLITE CELLS | CHONDROCYTE MATURATION | LASER-CAPTURE MICRODISSECTION | Paired Box Transcription Factors - genetics | Homeodomain Proteins - metabolism | Fractures, Bone - genetics | Bone Morphogenetic Protein 2 - metabolism | Muscle Proteins - metabolism | Cell Differentiation | Chondrogenesis | SOX9 Transcription Factor - metabolism | Bone Morphogenetic Protein 2 - genetics | PAX3 Transcription Factor | Cells, Cultured | Satellite Cells, Skeletal Muscle - metabolism | Transcription Factors - genetics | Chick Embryo | Fractures, Bone - metabolism | Homeodomain Proteins - genetics | Muscle Proteins - genetics | Transcription Factors - metabolism | Animals | Fracture Healing | Transforming Growth Factor beta - genetics | Chickens | Muscle Development - genetics | Mice | SOX9 Transcription Factor - genetics | Transforming Growth Factor beta - metabolism | Paired Box Transcription Factors - metabolism | Transforming growth factors | Bone morphogenetic proteins | Stem cells | Molecular machines | Biotechnology | Transcription factors | Biomedical research | Transcription | Sox9 protein | Nkx3.2 protein | Satellite cells | Myocytes | Proteins | Cartilage | Cell fate | Rodents | Cell cycle | Bone marrow | Pax3 protein | Bone morphogenetic protein 2 | Developmental biology | Muscles | Bone healing | Gene expression | Embryos | Progenitor cells | Myogenesis | Children & youth | Medicine | Regeneration | Musculoskeletal system | Fractures | Cellular biology | Chondrocytes | Cells (biology) | Healing | Mutation | Differentiation
Journal Article