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Biomaterials, ISSN 0142-9612, 2011, Volume 33, Issue 9, pp. 2801 - 2811
Abstract Complexing agents such as diethylene triamine pentaacetic acid (DTPA) are known to disrupt intestinal tight junctions and inhibit intestinal proteases... 
Advanced Basic Science | Dentistry | Proteolytic inhibition | Oral protein delivery | Molecular dynamic simulation | Complexing agent | Adherens junction | MATERIALS SCIENCE, BIOMATERIALS | ACID | ENGINEERING, BIOMEDICAL | CHITOSAN | RATS | PEPTIDE | AGENT | INJECTION | DRUGS | Nanoparticles - chemistry | Rats, Wistar | Tomography, Emission-Computed, Single-Photon | Biological Availability | Tomography, X-Ray Computed | Insulin - blood | Spectroscopy, Fourier Transform Infrared | Diabetes Mellitus, Experimental - blood | Protease Inhibitors - pharmacology | Pentetic Acid - chemistry | Protective Agents - pharmacology | Injections, Subcutaneous | Chitosan - chemical synthesis | Insulin - pharmacology | Tissue Distribution - drug effects | Administration, Oral | Rats | Insulin - administration & dosage | Electric Impedance | Cell Adhesion - drug effects | Static Electricity | Polyglutamic Acid - chemical synthesis | Molecular Dynamics Simulation | Blood Glucose - drug effects | Particle Size | Polyglutamic Acid - chemistry | Animals | Chitosan - chemistry | Diabetes Mellitus, Experimental - pathology | Absorption - drug effects | Drug Delivery Systems - methods | Insulin - pharmacokinetics | Nanoparticles | Biological products | Surface active agents | Blood sugar | Proteases | Permeability | Polyamines | Glutamate | Insulin | Diabetes therapy
Journal Article
Journal Article
Journal Article
Organic Letters, ISSN 1523-7060, 03/2014, Volume 16, Issue 5, pp. 1318 - 1321
A highly versatile synthetic strategy is described to generate multimodal and multivalent platforms based on a diethylenetriaminepentaacetic (DTPA) core.... 
AGENT | CYCLOADDITION | PEPTIDE DENDRIMERS | THERAPY | TRIAZINE DENDRIMERS | DRUG-DELIVERY | NANOMEDICINE | CHEMISTRY, ORGANIC | BIOMEDICAL APPLICATIONS | COMBINATION | Models, Molecular | Pentetic Acid - chemistry | Molecular Structure | Pentetic Acid - chemical synthesis | Chelating Agents
Journal Article
Organic Letters, ISSN 1523-7060, 04/2005, Volume 7, Issue 9, pp. 1719 - 1722
Journal Article
Journal of Biomaterials Science, Polymer Edition, ISSN 0920-5063, 08/2013, Volume 24, Issue 12, pp. 1472 - 1483
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2008, Volume 132, Issue 3, pp. 193 - 199
-(2-hydroxypropyl) methacrylamide (HPMA) copolymer-RGDfK conjugates targeting the α β integrin have shown increased accumulation in solid tumors and promise... 
Tumor targeting | Renal targeting | Biodistribution | HPMA copolymer | RGD | MOLECULAR-WEIGHT | ANGIOGENESIS | IN-VIVO BIODISTRIBUTION | COPOLYMERS | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDE | ALPHA(V)BETA | RADIONUCLIDE THERAPY | PHARMACOLOGY & PHARMACY | BINDING | Neoplasm Transplantation | Injections, Intravenous | Molecular Weight | Humans | Isothiocyanates - administration & dosage | Metabolic Clearance Rate | Pentetic Acid - administration & dosage | Pentetic Acid - analogs & derivatives | Acrylamides - pharmacokinetics | Integrin alphaVbeta3 - metabolism | Peptides, Cyclic - administration & dosage | Drug Carriers | Tissue Distribution | Kidney - metabolism | Kidney - diagnostic imaging | Carcinoma, Lewis Lung - diagnostic imaging | Female | Pentetic Acid - chemical synthesis | Binding, Competitive | Endothelial Cells - metabolism | Mice, Inbred C57BL | Isothiocyanates - blood | Carcinoma, Lewis Lung - metabolism | Pentetic Acid - pharmacokinetics | Chemistry, Pharmaceutical | Peptides, Cyclic - pharmacokinetics | Pentetic Acid - blood | Peptides, Cyclic - blood | Isothiocyanates - chemical synthesis | Animals | Acrylamides - administration & dosage | Peptides, Cyclic - chemical synthesis | Radionuclide Imaging | Cell Line, Tumor | Mice | Acrylamides - blood | Indium Radioisotopes | Acrylamides - chemical synthesis | Isothiocyanates - pharmacokinetics | Cyclohexane | Tumors | Index Medicus | HPMA Copolymer
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Journal Article
Journal Article
Journal Article