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Journal of Ethnopharmacology, ISSN 0378-8741, 11/2016, Volume 192, pp. 123 - 131
L. (Piperaceae) is a shrub found in the Amazon, Savannah and Atlantic Forest region of Brazil. It is widely used in folk medicine in many countries primarily... 
Flavonoids | Cytokines | Mechanism of action | Piper umbellatum | Anti-ulcer | ANTIOXIDANT ACTIVITY | CATALASE | CHEMISTRY, MEDICINAL | ESSENTIAL OILS | RATS | ASPIRIN | LESIONS | PLANT SCIENCES | INTEGRATIVE & COMPLEMENTARY MEDICINE | ETHANOL | PHARMACOLOGY & PHARMACY | STRESS | HELICOBACTER-PYLORI | PEPTIC-ULCER | Glutathione - metabolism | Plant Extracts - pharmacology | Solvents - chemistry | Stomach Ulcer - pathology | Helicobacter pylori - drug effects | Male | Stomach - metabolism | Dose-Response Relationship, Drug | Acetic Acid | Inflammation Mediators - metabolism | Anti-Ulcer Agents - pharmacology | Phytotherapy | Stomach - drug effects | Wound Healing - drug effects | Stomach Ulcer - prevention & control | Disease Models, Animal | Malondialdehyde - metabolism | Plant Leaves - chemistry | Stomach Ulcer - chemically induced | Acute Disease | Stomach Ulcer - metabolism | Stomach - pathology | Cytokines - metabolism | Ethanol | Plant Extracts - isolation & purification | Anti-Bacterial Agents - isolation & purification | Piper - chemistry | Catalase - metabolism | Animals | Anti-Bacterial Agents - pharmacology | Anti-Ulcer Agents - isolation & purification | Mice | Chronic Disease | Plants, Medicinal | Medicinal plants | Medicine, Herbal | Gastrointestinal diseases | Medicine, Botanic | Flavones | Analysis | Bioflavonoids | Peptic ulcer | Acetic acid | Organic acids | Antiulcer drugs
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2012, Volume 55, Issue 9, pp. 4446 - 4456
Journal Article
Lipids in Health and Disease, ISSN 1476-511X, 08/2017, Volume 16, Issue 1, pp. 152 - 12
Background: Massive alcohol drinking can lead to gastric ulcer. In the present study we investigated the gastroprotective effect of Citrus sinensis peel... 
COX-2 | Rat | TNF-α | Oxidative stress markers | Citrus sinensis peel | Gastric ulcer | Hesperidin | ANTIOXIDANT ACTIVITY | PROTEIN | ACID | TNF-alpha | BIOCHEMISTRY & MOLECULAR BIOLOGY | TISSUE | FLAVONOIDS | POLYPHENOLS | NUTRITION & DIETETICS | CALCIUM | EMBLICA-OFFICINALIS | Tumor Necrosis Factor-alpha - metabolism | Superoxide Dismutase - genetics | Oxidative Stress | Rats, Wistar | Plant Extracts - pharmacology | Tumor Necrosis Factor-alpha - genetics | Ethanol - administration & dosage | Stomach Ulcer - pathology | Male | Citrus sinensis - chemistry | Sulfhydryl Compounds - metabolism | Cyclooxygenase 2 - genetics | Anti-Ulcer Agents - pharmacology | Omeprazole - pharmacology | Stomach Ulcer - prevention & control | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | Stomach Ulcer - chemically induced | Glutathione Peroxidase - metabolism | Stomach Ulcer - metabolism | Catalase - genetics | Fruit - chemistry | Gene Expression Regulation | Rats | Antioxidants - pharmacology | Glutathione Peroxidase - genetics | Hydrogen Peroxide - metabolism | Catalase - metabolism | Animals | Cyclooxygenase 2 - metabolism | Hesperidin - pharmacology | Hydrogen Peroxide - antagonists & inhibitors | Sulfhydryl Compounds - agonists | Oxidative stress | Care and treatment | Peptic ulcer | Research | Orange | Health aspects | Risk factors
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 4/2016, Volume 389, Issue 4, pp. 403 - 417
Solidago chilensis Meyenmost (Asteraceae), popularly known as “Brazilian arnica” or “arnica-do-campo,” is widely used in the folk medicine to treat gastric... 
Neurosciences | Biomedicine | H + ,K + -ATPase | Quercitrin | Fibroblasts | Solidago chilensis | Afzelin | Pharmacology/Toxicology | Healing gastric ulcer | ATPase | ACID | RATS | PEPTIC-ULCER DISEASE | RADICAL SCAVENGING ACTIVITY | MURINE MODEL | H+,K+-ATPase | GASTRIC-ULCER | IN-VITRO | MEYEN | PHARMACOLOGY & PHARMACY | GROWTH-FACTOR | HELICOBACTER-PYLORI | Tumor Necrosis Factor-alpha - metabolism | Plant Extracts - chemistry | Proton Pump Inhibitors - pharmacology | Rats, Wistar | Glutathione - metabolism | Plant Extracts - pharmacology | Solvents - chemistry | Plant Leaves | Mannosides - isolation & purification | Stomach Ulcer - pathology | Gastric Mucosa - pathology | Gastric Mucosa - metabolism | Mannosides - chemistry | Proanthocyanidins - chemistry | Dose-Response Relationship, Drug | Proanthocyanidins - pharmacology | Quercetin - isolation & purification | Gastric Mucosa - drug effects | Anti-Ulcer Agents - pharmacology | Female | Phytotherapy | Methanol - chemistry | Wound Healing - drug effects | Stomach Ulcer - prevention & control | Disease Models, Animal | Fibroblasts - metabolism | Stomach Ulcer - chemically induced | Cell Line | Quercetin - analogs & derivatives | Rabbits | Stomach Ulcer - metabolism | H(+)-K(+)-Exchanging ATPase - metabolism | Quercetin - chemistry | Anti-Inflammatory Agents - pharmacology | Plant Extracts - isolation & purification | Fibroblasts - pathology | Animals | Anti-Ulcer Agents - chemistry | Quercetin - pharmacology | Fibroblasts - drug effects | Mannosides - pharmacology | Anti-Ulcer Agents - isolation & purification | Cell Proliferation - drug effects | Mice | Solidago - chemistry | Plants, Medicinal | Proanthocyanidins - isolation & purification | Hydrogen-Ion Concentration | Medicine, Herbal | Acetic acid | Analysis | Gastrointestinal diseases | Medicine, Botanic | Organic acids
Journal Article
Journal Article
Human & Experimental Toxicology, ISSN 0960-3271, 5/2019, Volume 38, Issue 5, pp. 510 - 518
Paeonol, a natural phenolic compound, possesses diverse beneficial effects including antioxidant and anti-inflammatory effects. Gastric ulcer is still the most... 
interleukin 1β | NAD(P)H quinone oxidoreductase 1 | nuclear factor κB | hemoxygenase-1 | caspase 3 | Paeonol | gastric ulcer | indomethacin | APOPTOSIS | OXIDATIVE STRESS | PERFORATED PEPTIC-ULCER | nuclear factor kappa B | INJURY | FACTOR-KAPPA-B | CROSS-TALK | interleukin 1 beta | NRF2 | CARBON-MONOXIDE | TOXICOLOGY | HEME OXYGENASE-1 | EXPRESSION | Malondialdehyde - metabolism | Stomach Ulcer - chemically induced | Anti-Ulcer Agents - therapeutic use | Stomach Ulcer - metabolism | Rats, Wistar | Glutathione - metabolism | Stomach Ulcer - drug therapy | Stomach Ulcer - pathology | Gastric Mucosa - pathology | Male | Interleukin-1beta - genetics | Gastric Mucosa - metabolism | Gene Expression Regulation - drug effects | Animals | Acetophenones - therapeutic use | NF-kappa B - genetics | Acetophenones - pharmacology | Caspase 3 - genetics | Gastric Mucosa - drug effects | Anti-Ulcer Agents - pharmacology | Indomethacin | Heme Oxygenase (Decyclizing) - genetics | Superoxide Dismutase - metabolism | Oxidative stress | Quinone oxidoreductase | Gastrointestinal tract diseases | Oxidoreductase | Mucosa | Interleukin | Gastric mucosa | Superoxide dismutase | Caspase-3 | Antioxidants | Proteins | Rodents | Pretreatment | Glutathione | NF-κB protein | Quinone | Caspase | Superoxide | Inflammation | Gene expression | IL-1β | Phenolic compounds | Malondialdehyde | NAD | Ulcers | Ranitidine | Phenols | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e84762
A rhamnogalacturonan (RGal) isolated from Acmella oleracea (L.) R.K. Jansen administered by oral route showed gastroprotective activity against acute lesions... 
OXYGEN | GASTRIC-ULCER | QUALITY | SPILANTHES-ACMELLA | MULTIDISCIPLINARY SCIENCES | GASTROINTESTINAL-TRACT | POLYSACCHARIDES | TISSUE | MECHANISMS | EXTRACT | Rats, Wistar | Glutathione - metabolism | Antioxidants - metabolism | Body Weight - drug effects | Stomach Ulcer - pathology | Gastric Mucosa - pathology | Stomach - metabolism | Gastric Mucosa - metabolism | Gastric Acid - secretion | Asteraceae - chemistry | Ethanol - adverse effects | Cytoprotection - drug effects | Gastric Mucosa - drug effects | Mucins - metabolism | Anti-Ulcer Agents - pharmacology | Female | Stomach - drug effects | Stomach Ulcer - chemically induced | Anti-Ulcer Agents - therapeutic use | Stomach Ulcer - metabolism | Pectins - therapeutic use | Stomach - pathology | Stomach Ulcer - drug therapy | Rats | Acetic Acid - adverse effects | Organ Size - drug effects | Pectins - pharmacology | Animals | Gastric Mucosa - secretion | Cell Proliferation - drug effects | Animal behavior | Wildlife conservation | Oxidative stress | Nuclear magnetic resonance--NMR | Ethanol | Mucosa | Gastric mucosa | Oral administration | Organs | Mucus | Biochemistry | Pharmacology | Inflammation | Kinases | Rhamnogalacturonan | Acids | Rodents | Ulcers | Healing | Nonsteroidal anti-inflammatory drugs | Lesions | Molecular biology | Laboratory animals | Food | Nuclear magnetic resonance | NMR
Journal Article
Journal Article
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