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1. Full Text Management of patients with ulcer bleeding
by Laine, Loren and Jensen, Dennis M
American Journal of Gastroenterology, ISSN 0002-9270, 03/2012, Volume 107, Issue 3, pp. 345 - 360
This guideline presents recommendations for the step-wise management of patients with overt upper gastrointestinal bleeding. Hemodynamic status is first... 
HEATER PROBE | BIPOLAR ELECTROCOAGULATION | UPPER-GASTROINTESTINAL HEMORRHAGE | LOW-DOSE ASPIRIN | NONBLEEDING VISIBLE VESSELS | ENDOSCOPIC INJECTION THERAPY | DOUBLE-BLIND | PROTON PUMP INHIBITORS | RANDOMIZED-TRIAL | GASTROENTEROLOGY & HEPATOLOGY | PEPTIC-ULCER | Fluid Therapy | Meta-Analysis as Topic | Prognosis | Resuscitation - methods | Risk Assessment | Humans | Endoscopy, Gastrointestinal | Clinical Trials as Topic | Secondary Prevention | Erythromycin - therapeutic use | Evidence-Based Medicine | Proton Pump Inhibitors - therapeutic use | Patient Selection | Peptic Ulcer Hemorrhage - therapy | Retreatment | Blood Transfusion | Hemostasis, Endoscopic - methods | Gastric Lavage | Peptic Ulcer Hemorrhage - diagnosis
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2. Full Text Management of Acute Bleeding from a Peptic Ulcer
by Gralnek, Ian M and Barkun, Alan N and Bardou, Marc
The New England Journal of Medicine, ISSN 0028-4793, 08/2008, Volume 359, Issue 9, pp. 928 - 937
The mortality associated with acute bleeding from a peptic ulcer remains high (5 to 10%), and the condition accounts for more than 400,000 hospital admissions... 
Risk Assessment - methods | Acute Disease | Radiography, Interventional | Humans | Peptic Ulcer Hemorrhage - surgery | Endoscopy, Gastrointestinal | Combined Modality Therapy | Embolization, Therapeutic | Proton Pump Inhibitors - therapeutic use | Hematemesis - etiology | Peptic Ulcer | Peptic Ulcer Hemorrhage - therapy | Peptic Ulcer Hemorrhage - complications | Triage | Peptic Ulcer Hemorrhage - diagnosis | Melena - etiology | Peptic ulcer | Causes of | Care and treatment | Diagnosis | Hemorrhage | Risk factors
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3. Full Text Time Trends and Impact of Upper and Lower Gastrointestinal Bleeding and Perforation in Clinical Practice
by Lanas, Angel and García-Rodríguez, Luis A and Polo-Tomás, Mónica and Ponce, Marta and Alonso-Abreu, Inmaculada and Perez-Aisa, Maria Angeles and Perez-Gisbert, Javier and Bujanda, Luis and Castro, Manuel and Mũoz, Maria and Rodrigo, Luis and Calvet, Xavier and Del-Pino, Dolores and Garcia, Santiago
The American Journal of Gastroenterology, ISSN 0002-9270, 07/2009, Volume 104, Issue 7, pp. 1633 - 1641
OBJECTIVES: Changing patterns in medical practice may contribute to temporal changes in the incidence of upper and lower gastrointestinal (GI) complications.... 
MORTALITY | EVENTS | CODES | DATABASE | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | NATIONWIDE | INHIBITORS | GASTROENTEROLOGY & HEPATOLOGY | PEPTIC-ULCER | ASPIRIN | POSITIVE PREDICTIVE-VALUE | Confidence Intervals | Age Distribution | Prognosis | Intestinal Perforation - epidemiology | Esophageal and Gastric Varices - therapy | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Peptic Ulcer Perforation - diagnosis | Esophageal and Gastric Varices - epidemiology | Gastrointestinal Hemorrhage - epidemiology | Incidence | Peptic Ulcer Perforation - epidemiology | Time Factors | Aged, 80 and over | Adult | Female | Retrospective Studies | Odds Ratio | Melena - therapy | Severity of Illness Index | Melena - diagnosis | Risk Assessment | Melena - epidemiology | Logistic Models | Esophageal and Gastric Varices - pathology | Gastrointestinal Hemorrhage - diagnosis | Intestinal Perforation - diagnosis | Peptic Ulcer Hemorrhage - therapy | Spain - epidemiology | Survival Analysis | Peptic Ulcer Hemorrhage - epidemiology | Sex Distribution | Aged | Peptic Ulcer Hemorrhage - diagnosis | Gastrointestinal Hemorrhage - pathology | Cohort Studies
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4. Full Text Intravenous Esomeprazole for Prevention of Recurrent Peptic Ulcer Bleeding A Randomized Trial
by Sung, JJY and Barkun, A and Kuipers, EJ and Mossner, J and Jensen, DM and Stuart, R and Lau, JY and Ahlbom, H and Kilhamn, J and Lind, T and Peptic Ulcer Bleed Study Grp and Peptic Ulcer Bleed Study Group
ANNALS OF INTERNAL MEDICINE, ISSN 0003-4819, 04/2009, Volume 150, Issue 7, pp. 455 - 455
Background: Use of proton-pump inhibitors in the management of peptic ulcer bleeding is controversial because discrepant results have been reported in... 
MEDICINE, GENERAL & INTERNAL | INTRAGASTRIC PH | METAANALYSIS | ENDOSCOPIC TREATMENT | COCHRANE-COLLABORATION | ACID SUPPRESSION | OMEPRAZOLE | PUMP INHIBITOR THERAPY | COAGULATION | CONTINUOUS-INFUSION | PLACEBO-CONTROLLED MULTICENTER | Proton Pump Inhibitors - adverse effects | Injections, Intravenous | Esomeprazole - administration & dosage | Follow-Up Studies | Humans | Middle Aged | Esomeprazole - adverse effects | Male | Combined Modality Therapy | Secondary Prevention | Peptic Ulcer Hemorrhage - therapy | Retreatment | Proton Pump Inhibitors - administration & dosage | Hemostasis, Endoscopic - methods | Peptic Ulcer Hemorrhage - prevention & control | Aged, 80 and over | Adult | Female | Aged | Infusions, Intravenous | Prevention | Complications and side effects | Peptic ulcer | Diagnosis | Drug therapy | Hemorrhage | Risk factors
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5. Full Text Systematic Review of the Predictors of Recurrent Hemorrhage After Endoscopic Hemostatic Therapy for Bleeding Peptic Ulcers
by Elmunzer, B. Joseph and Young, Scott D and Inadomi, John M and Schoenfeld, Philip and Laine, Loren
The American Journal of Gastroenterology, ISSN 0002-9270, 10/2008, Volume 103, Issue 10, pp. 2625 - 2632
An increased knowledge regarding the predictors of rebleeding after endoscopic therapy for bleeding ulcers should improve clinical management and outcomes. The... 
OUTPATIENT CARE | UPPER GASTROINTESTINAL HEMORRHAGE | RISK ASSESSMENT | INTENSIVE-CARE-UNIT | INJECTION THERAPY | DOUBLE-BLIND | ADRENALINE INJECTION | RANDOMIZED CONTROLLED-TRIAL | GASTROENTEROLOGY & HEPATOLOGY | PANTOPRAZOLE INFUSION | FAILURE | Peptic Ulcer Hemorrhage - therapy | Recurrence | United States - epidemiology | Prognosis | Humans | Hemostasis, Endoscopic - methods | Peptic Ulcer Hemorrhage - epidemiology | Peptic Ulcer Hemorrhage - diagnosis | Incidence | Peptic ulcer | Hemorrhage | Care and treatment
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6. Full Text The role of endoscopy in the management of patients with peptic ulcer disease
by Banerjee, Subhas and Cash, Brooks D and Dominitz, Jason A and Baron, Todd H and Anderson, Michelle A and Ben-Menachem, Tamir and Fisher, Laurel and Fukami, Norio and Harrison, M. Edwyn and Ikenberry, Steven O and Khan, Khalid and Krinsky, Mary Lee and Maple, John and Fanelli, Robert D and Strohmeyer, Laura and ASGE STAND PRACTICE COMM and ASGE Standards of Practice Committee
Gastrointestinal Endoscopy, ISSN 0016-5107, 2010, Volume 71, Issue 4, pp. 663 - 668
Gastroenterology and Hepatology | GIANT DUODENAL-ULCER | UNITED-STATES | DIAGNOSIS | RISK-FACTORS | GASTRIC OUTLET OBSTRUCTION | GASTROINTESTINAL-TRACT | PYLORIC-STENOSIS | DOUBLE-BLIND | TERM-FOLLOW-UP | BALLOON DILATION | GASTROENTEROLOGY & HEPATOLOGY | Humans | Peptic Ulcer Perforation - chemically induced | Stomach Ulcer - pathology | Duodenal Ulcer - chemically induced | Duodenal Ulcer - diagnosis | Gastric Mucosa - pathology | Helicobacter Infections - complications | Stomach Neoplasms - pathology | Peptic Ulcer Perforation - diagnosis | Helicobacter Infections - pathology | Helicobacter Infections - therapy | Peptic Ulcer Hemorrhage - pathology | Peptic Ulcer Perforation - therapy | Helicobacter pylori | Gastric Outlet Obstruction - diagnosis | Gastric Outlet Obstruction - therapy | Gastric Outlet Obstruction - pathology | Helicobacter Infections - diagnosis | Endoscopy, Digestive System | Duodenal Neoplasms - pathology | Stomach Ulcer - diagnosis | Stomach Ulcer - chemically induced | Diagnosis, Differential | Peptic Ulcer Perforation - pathology | Duodenal Ulcer - pathology | Stomach Neoplasms - diagnosis | Peptic Ulcer Hemorrhage - chemically induced | Stomach Neoplasms - therapy | Duodenal Neoplasms - therapy | Duodenal Neoplasms - diagnosis | Evidence-Based Medicine | Peptic Ulcer Hemorrhage - therapy | Duodenal Ulcer - therapy | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Biopsy | Duodenum - pathology | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Gastric Outlet Obstruction - chemically induced | Stomach Ulcer - therapy | Peptic Ulcer Hemorrhage - diagnosis | Intestinal Mucosa - pathology | Peptic ulcer | Care and treatment
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7. Full Text Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial
by Chan, Francis Ka Leung, Prof and Wong, Vincent Wai Sun, MD and Suen, Bing Yee, BSc and Wu, Justin Che Yuen, MD and Ching, Jessica Yuet Ling, MPH and Hung, Lawrence Cheung Tsui, MD and Hui, Aric Josun, MD and Leung, Vincent King Sun, MD and Lee, Vivian Wing Yan, PharmD and Lai, Larry Hin, MD and Wong, Grace Lai Hung, MD and Chow, Dorothy Kai Lai, MD and To, Ka Fa, MD and Leung, Wai Keung, MD and Chiu, Philip Wai Yan, MD and Lee, Yuk Tong, MD and Lau, James Yun Wong, MD and Chan, Henry Lik Yuen, MD and Ng, Enders Kwok Wai, MD and Sung, Joseph Jao Yiu, Prof
Lancet, The, ISSN 0140-6736, 2007, Volume 369, Issue 9573, pp. 1621 - 1626
Summary Background Guidelines on pain management recommend that patients at risk of ulcers receive either a cyclo-oxygenase (COX 2) inhibitor or a... 
Internal Medicine | ESOMEPRAZOLE | MEDICINE, GENERAL & INTERNAL | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | NSAID | CYCLOOXYGENASE-2 INHIBITORS | ARTHRITIS PATIENTS | NAPROXEN | COMPLICATIONS | HELICOBACTER-PYLORI | PEPTIC-ULCER | CELECOXIB | Pyrazoles - therapeutic use | Humans | Esomeprazole - adverse effects | Male | Secondary Prevention | Osteoarthritis - drug therapy | Esomeprazole - therapeutic use | Peptic Ulcer Hemorrhage - prevention & control | Female | Drug Therapy, Combination | Pyrazoles - adverse effects | Anti-Ulcer Agents - therapeutic use | Double-Blind Method | Proton Pump Inhibitors | Risk Factors | Anti-Ulcer Agents - adverse effects | Peptic Ulcer Hemorrhage - chemically induced | Treatment Outcome | Celecoxib | Peptic Ulcer Hemorrhage - therapy | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Sulfonamides - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Sulfonamides - adverse effects | Aged | Cyclooxygenase Inhibitors - adverse effects | Cyclooxygenase Inhibitors - therapeutic use | Prevention | Complications and side effects | COX-2 inhibitors | Relapse | Gastrointestinal bleeding | Peptic ulcer | Proton pump inhibitors | Dosage and administration | Drug therapy | Diseases | Drugs | Medical research | Physical examinations | Hospitals | Analgesics | Ulcers | Terminal illnesses | Clinical trials | Pharmaceuticals
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8. Full Text Independent risk factors of 30‐day outcomes in 1264 patients with peptic ulcer bleeding in the USA: large ulcers do worse
by Camus, M and Jensen, D. M and Kovacs, T. O and Jensen, M. E and Markovic, D and Gornbein, J
Alimentary Pharmacology & Therapeutics, ISSN 0269-2813, 05/2016, Volume 43, Issue 10, pp. 1080 - 1089
Summary Background Predictors of worse outcomes (rebleeding, surgery and death) of peptic ulcer bleeds (PUBs) are essential indicators because of significant... 
RECURRENT HEMORRHAGE | MORTALITY | METAANALYSIS | MANAGEMENT | EPINEPHRINE INJECTION | ENDOSCOPIC INJECTION THERAPY | PREDICTORS | PROTON PUMP INHIBITORS | PHARMACOLOGY & PHARMACY | GASTROENTEROLOGY & HEPATOLOGY | HEMOSTASIS | FAILURE | United States - epidemiology | Prospective Studies | Humans | Middle Aged | Risk Factors | Male | Proton Pump Inhibitors - therapeutic use | Histamine H2 Antagonists - therapeutic use | Peptic Ulcer Hemorrhage - therapy | Histamine H2 Antagonists - administration & dosage | Peptic Ulcer Hemorrhage - mortality | Proton Pump Inhibitors - administration & dosage | Hemostasis, Endoscopic - methods | Adult | Female | Aged | Histamine | Surgical clinics | Patient outcomes | Mortality | Peptic ulcer | Proton pump inhibitors | Risk factors | ulcer size | bleeding | stigmata of recent hemorrhage | peptic ulcer | outcomes
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9. Full Text Peptic ulcer disease
by Ramakrishnan, Kalyanakrishnan and Salinas, Robert C
American Family Physician, ISSN 0002-838X, 10/2007, Volume 76, Issue 7, pp. 1005 - 1013
Peptic ulcer disease usually occurs in the stomach and proximal duodenum. The predominant causes in the United States are infection with Helicobacter pylori... 
QUADRUPLE THERAPY | DUODENAL-ULCERS | MEDICINE, GENERAL & INTERNAL | RISK-FACTORS | METAANALYSIS | MANAGEMENT | ABDOMINAL-PAIN | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | HELICOBACTER-PYLORI ERADICATION | PROTON PUMP INHIBITORS | PRIMARY HEALTH CARE | PREVALENCE | Gastric Outlet Obstruction - etiology | Anti-Ulcer Agents - therapeutic use | Peptic Ulcer - complications | Humans | Helicobacter Infections - complications | Peptic Ulcer Perforation - diagnosis | Enzyme Inhibitors - therapeutic use | Histamine H2 Antagonists - therapeutic use | Peptic Ulcer Hemorrhage - etiology | Peptic Ulcer Perforation - therapy | Peptic Ulcer Hemorrhage - therapy | Algorithms | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Helicobacter pylori | Peptic Ulcer - therapy | Gastric Outlet Obstruction - diagnosis | Helicobacter Infections - drug therapy | Peptic Ulcer - diagnosis | Gastric Outlet Obstruction - therapy | Helicobacter Infections - diagnosis | Peptic Ulcer Hemorrhage - diagnosis | Peptic Ulcer - etiology | Peptic Ulcer Perforation - etiology | Peptic ulcer | Causes of | Diagnosis | Drug therapy
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10. Full Text Early clinical experience of the safety and effectiveness of Hemospray in achieving hemostasis in patients with acute peptic ulcer bleeding
by Sung, J. J and Luo, D and Wu, J. C and Ching, J. Y and Chan, F. K and Lau, J. Y and Mack, S and Ducharme, R and Okolo, P and Canto, M and Kalloo, A and Giday, S. A
Endoscopy, ISSN 0013-726X, 04/2011, Volume 43, Issue 4, pp. 291 - 295
Background and study aims: Endoscopic therapy of upper gastrointestinal bleeding remains challenging with conventional endoscopic devices. Use of Hemospray,... 
Original article | SURGERY | GASTROENTEROLOGY & HEPATOLOGY | Acute Disease | Humans | Middle Aged | Hemostasis, Endoscopic | Male | Nanoparticles | Peptic Ulcer Hemorrhage - therapy | Hemostatics - administration & dosage | Aged, 80 and over | Adult | Female | Aged | Powders - administration & dosage
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11. Full Text Epinephrine injection versus epinephrine injection and a second endoscopic method in high-risk bleeding ulcers
by Vergara, Mercedes and Vergara, Mercedes and Bennett, Cathy and Bennett, Cathy and Calvet, Xavier and Calvet, Xavier and Gisbert, Javier P and Gisbert, Javier P
The Cochrane database of systematic reviews, ISSN 1469-493X, 2014, Volume 2014, Issue 10, p. CD005584
Background Endoscopic therapy reduces the rebleeding rate and the need for surgery in patients with bleeding peptic ulcers. Objectives To determine whether a... 
HEMOSTATIC EFFICACY | UPPER GASTROINTESTINAL HEMORRHAGE | Humans | PLUS ARGON PLASMA | RANDOMIZED-TRIAL | COMBINATION | Combined Modality Therapy [methods] | Randomized Controlled Trials as Topic | Vasoconstrictor Agents [administration & dosage] | Recurrence [prevention & control] | Epinephrine [administration & dosage] | MEDICINE, GENERAL & INTERNAL | THERAPY | Hemostasis, Endoscopic [methods] | HEMOCLIPS | ADRENALINE INJECTION | COAGULATION | Peptic Ulcer Hemorrhage [mortality; prevention & control; therapy] | PEPTIC-ULCER | Peptic Ulcer Hemorrhage - therapy | Peptic Ulcer Hemorrhage - mortality | Vasoconstrictor Agents - administration & dosage | Hemostasis, Endoscopic - methods | Peptic Ulcer Hemorrhage - prevention & control | Epinephrine - administration & dosage | Adult | Combined Modality Therapy - methods | Secondary Prevention - methods
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12. Full Text Weekend Versus Weekday Admission and Mortality From Gastrointestinal Hemorrhage Caused by Peptic Ulcer Disease
by Shaheen, Abdel Aziz M and Kaplan, Gilaad G and Myers, Robert P
Clinical Gastroenterology and Hepatology, ISSN 1542-3565, 2009, Volume 7, Issue 3, pp. 303 - 310
Background & Aims Management of upper gastrointestinal bleeding (UGIB) often requires urgent endoscopic intervention; limitations in its availability on... 
Gastroenterology and Hepatology | DISCHARGE | ENDOSCOPY | HOSPITALIZED-PATIENTS | COST | CIRRHOSIS | PATIENT | TIME | OUTCOMES | GASTROENTEROLOGY & HEPATOLOGY | CARE | EPIDEMIOLOGY | Peptic Ulcer - complications | Hospital Mortality | United States | Humans | Middle Aged | Male | Treatment Outcome | Hospitalization | Health Services Research | Peptic Ulcer Hemorrhage - therapy | Peptic Ulcer Hemorrhage - mortality | Time Factors | Hospital Charges - statistics & numerical data | Female | Patient Care - statistics & numerical data | Aged | Endoscopy | Length of Stay - statistics & numerical data | Peptic ulcer | Cytogenetics | Gastrointestinal bleeding | Health aspects | Mortality | Medical care, Cost of
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13. Full Text Gastric Ulcer Bleeding Due to Left Gastric Artery Pseudoaneurysm
by Sudo, Gota and Tanuma, Tokuma and Nakase, Hiroshi
American Journal of Gastroenterology, ISSN 0002-9270, 09/2018, Volume 113, Issue 9, pp. 1281 - 1281
GASTROENTEROLOGY & HEPATOLOGY | Aneurysm, False - complications | Angiography | Humans | Stomach - blood supply | Male | Treatment Outcome | Embolization, Therapeutic | Gastric Artery - pathology | Hematemesis - etiology | Peptic Ulcer Hemorrhage - etiology | Peptic Ulcer Hemorrhage - therapy | Stomach Ulcer - complications | Stomach Ulcer - diagnostic imaging | Aneurysm, False - therapy | Aged | Aneurysm, False - diagnosis | Hematemesis - therapy | Endoscopy, Digestive System | Gastric Artery - diagnostic imaging | Peptic Ulcer Hemorrhage - diagnosis | Stomach - diagnostic imaging | Hematemesis - diagnosis
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