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Proceedings of the National Academy of Sciences, ISSN 0027-8424, 07/2012, Volume 109, Issue 27, pp. E1839 - E1847
.... The dynamics of apoptosis involve a number of previously identified, caspase-generated proapoptotic protein fragments, defined as those that increase the probability of apoptosis... 
ATE1 | Arginylation | UBR1 | Proteolysis | APOPTOSIS | ACTIVATION | UBIQUITIN LIGASE | MULTIDISCIPLINARY SCIENCES | KAPPA-B | DEGRADATION SIGNALS | CANCER | arginylation | CASPASES | RIP | proteolysis | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Humans | Aminoacyltransferases - genetics | Caspase 3 - metabolism | bcl-X Protein - genetics | BH3 Interacting Domain Death Agonist Protein - genetics | Phosphoproteins - metabolism | Lim Kinases - metabolism | Mice, Mutant Strains | BRCA1 Protein - metabolism | HEK293 Cells | Antibodies - immunology | Apoptosis Regulatory Proteins - genetics | Peptide Fragments - genetics | BH3 Interacting Domain Death Agonist Protein - metabolism | Rabbits | Peptide Fragments - metabolism | TNF Receptor-Associated Factor 1 - metabolism | Ubiquitin-Protein Ligases - metabolism | TNF Receptor-Associated Factor 1 - genetics | Phosphoproteins - genetics | Apoptosis Regulatory Proteins - metabolism | BRCA1 Protein - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Adaptor Proteins, Signal Transducing - genetics | Lim Kinases - genetics | Aminoacyltransferases - metabolism | Mice | Apoptosis - physiology | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | bcl-X Protein - metabolism | Arginine - metabolism | Biological Sciences | PNAS Plus
Journal Article
Journal of the American Society of Nephrology, ISSN 1533-3450, 2017, Volume 28, Issue 9, pp. 2694 - 2707
...) or the 11-residue furin-cleaved fragment (ELA11) to hypoxia-reperfusion (H/R)-injured or adriamycin-treated renal tubular cells in vitro... 
ISCHEMIA-REPERFUSION INJURY | ACUTE KIDNEY INJURY | APOPTOSIS | DNA-DAMAGE RESPONSE | INFLAMMATION | UROLOGY & NEPHROLOGY | ACUTE-RENAL-FAILURE | ENDOPLASMIC-RETICULUM STRESS | RETINAL INJURY | APELIN RECEPTOR | PROXIMAL TUBULE | Cell Adhesion Molecules - genetics | Peptide Hormones - pharmacology | Phosphorylation | Ataxia Telangiectasia Mutated Proteins - metabolism | Gene Expression - drug effects | Apoptosis - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Peptide Fragments - pharmacology | Acute Kidney Injury - genetics | Hepatitis A Virus Cellular Receptor 1 - genetics | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Autophagy - drug effects | Cell Hypoxia | Carrier Proteins - pharmacology | Carrier Proteins - therapeutic use | Peptide Fragments - genetics | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Cell Line | Cell Survival - drug effects | DNA Repair - drug effects | Interleukin-6 - genetics | Rats | Transforming Growth Factor beta1 - genetics | Acute Kidney Injury - physiopathology | Acute Kidney Injury - prevention & control | Kidney Tubules - cytology | Carrier Proteins - genetics | Checkpoint Kinase 1 - metabolism | Animals | Reperfusion Injury - prevention & control | Intercellular Adhesion Molecule-1 - genetics | Reperfusion Injury - physiopathology | Inflammation - genetics | Peptide Hormones - therapeutic use | Inflammation - prevention & control | Mice | Peptide Fragments - therapeutic use | Histones - metabolism | Acute Kidney Injury - metabolism | acute kidney injury | ELABELA | DNA damage response | inflammation | Basic Research
Journal Article
The EMBO Journal, ISSN 0261-4189, 09/2015, Volume 34, Issue 17, pp. 2255 - 2271
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2019, Volume 116, Issue 9, pp. 3746 - 3751
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2013, Volume 123, Issue 11, pp. 4627 - 4640
Journal Article
The Plant cell, ISSN 1040-4651, 7/2017, Volume 29, Issue 7, pp. 1571 - 1584
Pathogenic gram-negative bacteria cause serious diseases in animals and plants. These bacterial pathogens use the type III secretion system (T3SS) to deliver... 
BREAKTHROUGH REPORT | TRANSLOCATION | IMMUNITY | PATHOGEN | MECHANISM | ARABIDOPSIS EDS1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DELIVERY | PLANT SCIENCES | CELL BIOLOGY | DISEASE | REQUIRES | TRANSIENT | TOMATO | Recombinant Proteins - metabolism | Green Fluorescent Proteins - metabolism | Peptide Fragments - metabolism | Green Fluorescent Proteins - analysis | Pseudomonas syringae - metabolism | Bacterial Proteins - genetics | Recombinant Proteins - chemistry | Molecular Imaging - methods | Plant Diseases - microbiology | Green Fluorescent Proteins - genetics | Recombinant Proteins - genetics | Protein Folding | Pseudomonas syringae - pathogenicity | Arabidopsis - genetics | Host-Pathogen Interactions | Peptide Fragments - analysis | Arabidopsis - microbiology | Tobacco - genetics | Plants, Genetically Modified | Bacterial Proteins - metabolism | Tobacco - microbiology | Peptide Fragments - genetics | Host-bacteria relationships | Physiological aspects | Observations | Pseudomonas syringae | Fluorescent proteins | Proteins | Arabidopsis thaliana | Immune response | Fluorescence | Bacteria | Genetic engineering | Plants | Pathogens | Effector cells | Animal diseases | Pseudomonas | Transgenic plants | Biological activity | Plant cells | Dynamic tests | Compartments | Effectors | Green fluorescent protein | Gram-negative bacteria | Localization | Breakthrough Reports
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 340, Issue 6128, pp. 87 - 91
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 3/2002, Volume 99, Issue 6, pp. 3469 - 3474
We have defined inactive α and ω fragments of β-lactamase that can complement to form a functional enzyme in both bacteria and mammalian cells, serving as a readout for the interaction of proteins fused to the fragments... 
Proteins | Enzymes | Biological Sciences | Drug interactions | Cell lines | Fluorescence | Bacteria | Complementation | Libraries | Dimerization | Cells | GALACTOSIDASE COMPLEMENTATION | REPORTER | ACTIVATION | COMPLEX | DOMAIN | CLONAL SELECTION | MULTIDISCIPLINARY SCIENCES | QUANTITATION | EUKARYOTIC CELLS | DIMERIZATION | LIGAND | Peptides - genetics | Genetic Complementation Test | Recombinant Fusion Proteins - metabolism | Flow Cytometry | Peptides - metabolism | beta-Lactamases - genetics | Retroviridae - genetics | Escherichia coli - metabolism | beta-Lactamases - metabolism | Muscles - metabolism | Peptide Fragments - genetics | Proto-Oncogene Proteins c-fos - chemistry | Cell Line | Peptide Fragments - metabolism | Escherichia coli - enzymology | Transduction, Genetic | Peptides - chemistry | Proto-Oncogene Proteins c-fos - metabolism | Models, Molecular | Recombinant Fusion Proteins - chemistry | Organ Specificity | Blotting, Western | beta-Lactamases - chemistry | Peptide Fragments - chemistry | Animals | Escherichia coli - genetics | Fluorescent Antibody Technique | Protein Binding | Recombinant Fusion Proteins - genetics | Protein Conformation | Proto-Oncogene Proteins c-fos - genetics | Mice | Microscopy, Fluorescence | Muscles - cytology
Journal Article
Analytical Chemistry, ISSN 0003-2700, 11/2018, Volume 90, Issue 22, pp. 13299 - 13305
.... In this work, we reported a three-fragment fluorescence complementation (TFFC) by splitting the Venus fluorescent protein for visualizing ternary complexes in living cells under physiological conditions... 
VISUALIZATION | CHEMISTRY, ANALYTICAL | PROTEIN | INTEGRATION | BAF | LEDGF/P75 | MICROSCOPY | LIVING CELLS | RETROVIRAL DNA | AUTOINTEGRATION | Humans | Protein Multimerization | Bacterial Proteins - chemistry | Cercopithecus aethiops | Fluorescence | Multiprotein Complexes - genetics | HIV Integrase - metabolism | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | HEK293 Cells | Luminescent Proteins - chemistry | Nuclear Proteins - genetics | Peptide Fragments - genetics | Vero Cells | Proto-Oncogene Proteins c-jun - genetics | NFATC Transcription Factors - metabolism | Bacterial Proteins - genetics | Proto-Oncogene Proteins c-fos - metabolism | Nuclear Proteins - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Microscopy, Confocal - methods | Transcription Factors - metabolism | Peptide Fragments - chemistry | Animals | HIV Integrase - genetics | Microscopy, Fluorescence - methods | Multiprotein Complexes - analysis | Virus Integration - physiology | Proto-Oncogene Proteins c-jun - metabolism | Adaptor Proteins, Signal Transducing - genetics | Protein Binding | Luminescent Proteins - genetics | Proto-Oncogene Proteins c-fos - genetics | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | NFATC Transcription Factors - genetics | Proteins | Visualization | Integration | Molecular modelling | Human immunodeficiency virus--HIV | Cells (biology) | Identification | Physiology | Protein interaction
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2015, Volume 36, Issue 3, pp. 1601.e7 - 1601.e16
Journal Article
Oncology Reports, ISSN 1021-335X, 08/2017, Volume 38, Issue 2, pp. 755 - 766
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e81111
.... We hypothesized that chromogranin A fragments were differentially expressed during NEN metastasis and played a role in the regulation of NEN proliferation. Methods... 
REAL-TIME PCR | PROTEOLYTIC CLEAVAGE | TUMOR DISEASE | PROGNOSTIC-FACTORS | CHROMAFFIN GRANULES | PROHORMONE CONVERTASE-1 | MULTIDISCIPLINARY SCIENCES | KRJ-I | VASOSTATIN | GENE-TRANSFER | CELL-LINES | Proprotein Convertases - antagonists & inhibitors | RNA, Small Interfering - genetics | Phosphorylation | Cell Proliferation | TOR Serine-Threonine Kinases - metabolism | Humans | Gene Expression Regulation, Neoplastic | Peptide Fragments - pharmacology | RNA, Messenger - metabolism | Proprotein Convertases - genetics | Proto-Oncogene Proteins c-akt - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | TOR Serine-Threonine Kinases - genetics | Calreticulin - metabolism | Chromogranin A - metabolism | Chromogranin A - genetics | Liver Neoplasms - secondary | Proto-Oncogene Proteins c-akt - metabolism | Everolimus | Intestinal Neoplasms - genetics | Calreticulin - pharmacology | Peptide Fragments - metabolism | Sirolimus - analogs & derivatives | Liver Neoplasms - genetics | Signal Transduction | Cell Survival | Neuroendocrine Tumors - metabolism | Intestinal Neoplasms - metabolism | Proprotein Convertases - metabolism | RNA, Messenger - genetics | Sirolimus - pharmacology | Intestinal Neoplasms - pathology | Neuroendocrine Tumors - genetics | Neuroendocrine Tumors - secondary | Liver Neoplasms - metabolism | Cell Line, Tumor | Chromogranin A - antagonists & inhibitors | RNA, Small Interfering - metabolism | RNA | Enzyme-linked immunosorbent assay | Metastasis | TOR protein | Biotechnology | Peptides | Liver | Mucosa | Bromodeoxyuridine | Amino acids | Antisense | AKT protein | mRNA | Metastases | Fragmentation | Proteins | Signal transduction | Prohormone convertase | Cell growth |