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Immunity (Cambridge, Mass.), ISSN 1074-7613, 2008, Volume 28, Issue 3, pp. 425 - 435
Journal Article
Mucosal immunology, ISSN 1933-0219, 2009, Volume 2, Issue 5, pp. 412 - 426
AIDS is mainly a sexually transmitted disease, and accordingly, mucosal tissues are the primary sites of natural human immunodeficiency virus type-1 (HIV-1)... 
VACCINE CANDIDATE | CRYSTAL-STRUCTURE | SECRETORY IGA | GALACTOSYL CERAMIDE | SEX WORKERS | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | TYPE-1 ANTIBODY 2F5 | STEP PURIFICATION | MEMBRANE-PROXIMAL REGION | F-AB FRAGMENT | HIV Infections - prevention & control | HIV Envelope Protein gp41 - immunology | Humans | Vagina - immunology | Molecular Sequence Data | Immunoglobulin A, Secretory - isolation & purification | Peptide Library | HIV Antibodies - isolation & purification | Virus Internalization | CD4-Positive T-Lymphocytes - immunology | Sequence Homology | HIV Infections - immunology | Immunoglobulin A, Secretory - genetics | HIV-1 - physiology | HIV Antibodies - immunology | Peptide Fragments - immunology | Conserved Sequence | Adult | Female | Gene Rearrangement, B-Lymphocyte | CD4-Positive T-Lymphocytes - virology | Antibodies, Monoclonal - immunology | Amino Acid Sequence | Immunoglobulin Fab Fragments - genetics | Immunoglobulin A, Secretory - immunology | Antibodies, Monoclonal - isolation & purification | Environmental Exposure | HIV Seronegativity - immunology | Antibodies, Monoclonal - genetics | Immunity, Innate - immunology | HIV-1 - immunology | Sequence Alignment | Mucous Membrane - immunology | Cervix Uteri - immunology | HIV Antibodies - genetics | Immunoglobulin Fab Fragments - immunology | Sexual Partners | Index Medicus | HIV Infections | HIV-1 | Peptide Fragments | HIV Antibodies | Mucous Membrane | Life Sciences | CD4-Positive T-Lymphocytes | Immunoglobulin Fab Fragments | Immunoglobulin A, Secretory | HIV Seronegativity | HIV Envelope Protein gp41 | Vagina | Antibodies, Monoclonal | Immunity, Innate | Cervix Uteri | Microbiology and Parasitology
Journal Article
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2017, Volume 199, Issue 3, pp. 1105 - 1112
Serum amyloid A (SAA) is known as an acute-phase protein and a biomarker for inflammatory diseases. Published studies have shown that SAA possesses... 
FIBRIL FORMATION | CELLS | ARTHRITIS SYNOVIAL TISSUE | IN-VITRO | HUMAN NEUTROPHILS | PROTEIN-COUPLED RECEPTOR | PATHWAY | FORMYL PEPTIDE RECEPTOR | INDUCTION | IMMUNOLOGY | EXPRESSION | Serum Amyloid A Protein - pharmacology | Lipopolysaccharides - administration & dosage | Tumor Necrosis Factor-alpha - genetics | Receptors, Formyl Peptide - immunology | Interleukin-1beta - genetics | Lipopolysaccharides - immunology | Receptors, Formyl Peptide - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-1beta - biosynthesis | Macrophages - immunology | Serum Amyloid A Protein - metabolism | Interleukin-6 - genetics | Signal Transduction | Interleukin-1beta - immunology | Toll-Like Receptor 3 - immunology | Inflammation - immunology | Chemotaxis - drug effects | Serum Amyloid A Protein - immunology | Animals | Serum Amyloid A Protein - chemistry | Interleukin-10 - genetics | Interleukin-6 - immunology | Interleukin-6 - biosynthesis | Toll-Like Receptor 2 - immunology | Interleukin-10 - biosynthesis | Mice | Interleukin-10 - immunology | Tumor Necrosis Factor-alpha - biosynthesis | Phosphorylation | Calcium | Switches | Inflammatory response | Macrophages | Inflammatory diseases | Lipopolysaccharides | Lethal dose | Interleukin 6 | Proteins | Phagocytes | Proteolysis | Rodents | Toll-like receptors | Amyloid | Extracellular signal-regulated kinase | MAP kinase | JNK protein | TLR4 protein | Tumor necrosis factor-α | Chemotaxis | Acute phase substances | Injury prevention | Lungs | TLR2 protein | Interleukin 10 | Biomarkers | Infiltration | Amyloidosis | Structure-function relationships
Journal Article
Allergy (Copenhagen), ISSN 0105-4538, 2018, Volume 73, Issue 7, pp. 1425 - 1435
... with two hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1 in a nonallergic subject. Methods A phage... 
allergy | combinatorial cloning | recombinant hypoallergenic allergen derivative | IgG antibody | Bet v 1 | CONTIGUOUS OVERLAPPING PEPTIDES | EFFICACY | MECHANISMS | IMMUNOLOGY | HAY-FEVER | BIRCH POLLEN ALLERGEN | RESPONSES | IMMUNOTHERAPY | RECOMBINANT | MONOCLONAL-ANTIBODIES | DERIVATIVES | Surface Plasmon Resonance | Amino Acid Sequence | Immunoglobulin G - isolation & purification | Leukocytes, Mononuclear - metabolism | Immunization | Gene Library | Humans | Immunoglobulin G - chemistry | Antigens, Plant - immunology | Cross Reactions - immunology | Epitopes - immunology | Immunoglobulin E - immunology | Immunoglobulin G - genetics | Single-Chain Antibodies - genetics | Single-Chain Antibodies - isolation & purification | Allergens - immunology | Antibody Specificity - immunology | Immunoglobulin G - immunology | Base Sequence | Leukocytes, Mononuclear - immunology | Basophils - immunology | Basophils - metabolism | Single-Chain Antibodies - chemistry | Single-Chain Antibodies - immunology | Antigen-antibody reactions | Food allergy | Allergens | Immunogenetics | Analysis | Immunoglobulin G | Vaccination | Immunoglobulin E | Derivatives (Financial instruments) | Antigenic determinants | Phages | Antibodies | Homology | Activation | Fragmentation | Immunotherapy | Epitope mapping | Pollen | Food hypersensitivity | Enzyme-linked immunosorbent assay | Binding | Immunoglobulins | Bet v 1 antigen | Fragments | Derivatives | Patients | Allergies | Affinity | Surface plasmon resonance | Gene mapping | Combinatorial analysis | ORIGINAL ARTICLES | Original
Journal Article
Nature communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, p. 24
Neuroinflammation caused by local deposits of A beta(42) in the brain is key for the pathogenesis and progression of Alzheimer's disease. However, inflammation... 
STROKE | SYSTEM | IMMUNE-RESPONSE | ENERGY HOMEOSTASIS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | NEURODEGENERATION | MECHANISMS | MODEL | BRAIN | COMMUNICATION | Antimicrobial Cationic Peptides - immunology | Alzheimer Disease - complications | Brain - microbiology | Drosophila melanogaster - immunology | Hemocytes - immunology | Humans | Tumor Necrosis Factor-alpha - genetics | MAP Kinase Kinase 4 - immunology | Drosophila Proteins - immunology | Dysbiosis - microbiology | Enterobacteriaceae Infections - complications | Alzheimer Disease - pathology | Cell Movement - immunology | Enterobacteriaceae Infections - immunology | Hemocytes - pathology | Dysbiosis - immunology | Gastrointestinal Tract - immunology | Enterobacteriaceae - immunology | Leukocyte Reduction Procedures | Amyloid beta-Peptides - genetics | Peptide Fragments - immunology | Tumor Necrosis Factor-alpha - immunology | Hemocytes - microbiology | Alzheimer Disease - immunology | Antimicrobial Cationic Peptides - genetics | Peptide Fragments - genetics | Enterobacteriaceae - growth & development | Disease Models, Animal | Alzheimer Disease - microbiology | Microbiota - immunology | Signal Transduction | Enterobacteriaceae Infections - microbiology | Gene Expression Regulation | Gastrointestinal Tract - microbiology | Enterobacteriaceae Infections - pathology | Dysbiosis - complications | Disease Progression | Drosophila melanogaster - microbiology | Animals | Brain - pathology | MAP Kinase Kinase 4 - genetics | Amyloid beta-Peptides - immunology | Drosophila Proteins - genetics | Dysbiosis - pathology | Brain - immunology
Journal Article
Clinical and experimental immunology, ISSN 0009-9104, 2012, Volume 167, Issue 1, pp. 137 - 148
Summary The ready access to commercially available multiplex assays and the importance of inflammation in disease pathogenesis has resulted in an abundance of... 
hepatitis C virus | chemokines/monokines | bladder cancer | BCG | Hepatitis C virus | Bladder cancer | Chemokines/monokines | BACILLUS-CALMETTE-GUERIN | DIPEPTIDYL-PEPTIDASE-IV | LIGANDS CXCL9 | IFN-GAMMA | CHEMOKINE RECEPTOR CXCR3 | HEPATITIS-C-VIRUS | monokines | IMMUNOLOGY | chemokines | INTERFERON-INDUCIBLE PROTEIN-10 | LEVELS CORRELATE | ADAPTIVE IMMUNE-RESPONSES | CEREBRAL MALARIA | Enzyme-Linked Immunosorbent Assay - methods | Dipeptidyl Peptidase 4 - metabolism | Carcinoma, Transitional Cell - urine | Humans | Middle Aged | Culture Media, Conditioned - chemistry | Recombinant Fusion Proteins - analysis | Male | Neoplasm Proteins - urine | Chemokine CXCL10 - analysis | Peptide Fragments - immunology | Chemokine CXCL10 - immunology | Aged, 80 and over | Adult | Female | Antibodies, Monoclonal - immunology | Protein Structure, Tertiary | Urinary Bladder Neoplasms - urine | Body Fluids - chemistry | Protein Isoforms - analysis | Inflammation | Hepatitis C, Chronic - blood | Peptide Fragments - analysis | Immunoenzyme Techniques - methods | Biomarkers | Aged | Protein Processing, Post-Translational | Protein Isoforms - immunology | Universities and colleges | Dendritic cells | Hepatitis C | Atopic dermatitis | Hepatitis | Pathogenesis | Discrimination | Urine | CD26 antigen | biomarkers | Abundance | Inflammatory diseases | Asthma | Tuberculosis | CXCL10 protein | Post-translation | Immunoassays | Injuries | Cancer | Kidney transplantation | Recombinant Fusion Proteins/analysis | Chemokine CXCL10/analysis | Hepatitis C, Chronic/blood | Culture Media, Conditioned/chemistry | Carcinoma, Transitional Cell/urine | Life Sciences | Chemokine CXCL10/immunology | Antibodies, Monoclonal/immunology | Immunology | Neoplasm Proteins/urine | Protein Isoforms/immunology | Urinary Bladder Neoplasms/urine | Body Fluids/chemistry | Peptide Fragments/immunology | Protein Isoforms/analysis | Enzyme-Linked Immunosorbent Assay/methods | Dipeptidyl Peptidase 4/metabolism | Immunoenzyme Techniques/methods | Peptide Fragments/analysis | Translational Studies
Journal Article
Biochemistry (Easton), ISSN 0006-2960, 02/2019, Volume 58, Issue 6, pp. 763 - 775
Multiple sclerosis (MS) is an autoimmune disorder manifested via chronic inflammation, demyelination, and neurodegeneration inside the central nervous system.... 
ENCEPHALOMYELITIS | PATHOGENESIS | MULTIPLE-SCLEROSIS | MAMMALIAN PRIONS | MODELS | MECHANISM | AUTOIMMUNITY | ALZHEIMERS-DISEASE | RELEVANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOPROTEIN | Myelin-Oligodendrocyte Glycoprotein - immunology | Citrullination - immunology | Peptide Fragments - toxicity | Humans | Amyloidogenic Proteins - immunology | Amyloid - toxicity | Myelin-Oligodendrocyte Glycoprotein - toxicity | Amyloid - metabolism | Myelin-Oligodendrocyte Glycoprotein - chemical synthesis | T-Lymphocytes - metabolism | Peptide Fragments - immunology | B-Lymphocytes - virology | B-Lymphocytes - pathology | B-Lymphocytes - metabolism | Dendritic Cells - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Peptide Fragments - metabolism | Multiple Sclerosis, Chronic Progressive - immunology | Callithrix | Mice, Inbred C57BL | Recombinant Proteins - chemistry | Multiple Sclerosis, Chronic Progressive - metabolism | Amyloidogenic Proteins - toxicity | Herpesvirus 4, Human | Protein Aggregation, Pathological | Peptide Fragments - chemical synthesis | Amyloidogenic Proteins - metabolism | Multiple Sclerosis, Chronic Progressive - virology | Animals | B-Lymphocytes - immunology | Myelin-Oligodendrocyte Glycoprotein - metabolism | Amyloidogenic Proteins - chemical synthesis | Recombinant Proteins - immunology | Amyloid - immunology | Benzothiazoles - chemistry | Recombinant Proteins - toxicity | T-Lymphocytes - immunology | Index Medicus
Journal Article
Nature structural & molecular biology, ISSN 1545-9985, 2013, Volume 20, Issue 7, pp. 804 - 813
HIV-1 uses a diverse N-linked-glycan shield to evade recognition by antibody. Select human antibodies, such as the clonally related PG9 and PG16, recognize... 
COMPLEX | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GP120 | 2G12 RECOGNIZES | GLYCOSYLATION SITES | CELL BIOLOGY | POTENT | BIOPHYSICS | HAMSTER OVARY CELLS | BROADLY NEUTRALIZING ANTIBODIES | IMMUNODEFICIENCY-VIRUS TYPE-1 | HIV-1 ENVELOPE GLYCOPROTEINS | Antibody Specificity | Epitopes - metabolism | Humans | Antibodies, Neutralizing - metabolism | Molecular Sequence Data | Crystallography, X-Ray | Structure-Activity Relationship | Glycosylation - drug effects | HIV Envelope Protein gp120 - metabolism | Antigen-Antibody Reactions | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | Immunoglobulin Fab Fragments - metabolism | Protein Processing, Post-Translational - drug effects | Peptide Fragments - immunology | HEK293 Cells | Polysaccharides - chemistry | HIV Envelope Protein gp120 - chemistry | Swainsonine - pharmacology | Carbohydrate Sequence | HIV Antibodies - metabolism | Amino Acid Sequence | Peptide Fragments - metabolism | Models, Molecular | Polysaccharides - immunology | HIV Antibodies - chemistry | Amino Acid Motifs | Polysaccharides - metabolism | Peptide Fragments - chemistry | Antibodies, Neutralizing - chemistry | Protein Conformation | Epitopes - chemistry | Immunoglobulin Fab Fragments - immunology | Binding Sites, Antibody | Carbohydrate Conformation | Antigen-antibody reactions | Physiological aspects | Genetic aspects | Research | HIV (Viruses) | Structure | Health aspects | Antigenic determinants | Mutagenesis | Molecular biology | Human immunodeficiency virus--HIV | Polyclonal antibodies
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2013, Volume 38, Issue 2, pp. 275 - 284
Epidermal growth factor receptor (EGFR) is known to be critically involved in tissue development and homeostasis as well as in the pathogenesis of cancer. Here... 
CETUXIMAB | RESPONSES | TOLERANCE | MAST-CELLS | DISEASE | MODEL | IMMUNOLOGY | CARCINOMA | EXPRESSION | METASTATIC COLORECTAL-CANCER | EGF RECEPTOR | Forkhead Transcription Factors - immunology | Cell Communication - immunology | Receptor, Epidermal Growth Factor - genetics | T-Lymphocytes, Regulatory - metabolism | Humans | Colitis - pathology | Homeodomain Proteins - immunology | Amphiregulin | Glycoproteins - pharmacology | T-Lymphocytes, Regulatory - immunology | Signal Transduction - immunology | Melanoma, Experimental - immunology | EGF Family of Proteins | Colitis - chemically induced | Peptide Fragments - immunology | Mast Cells - metabolism | Colitis - immunology | Glycoproteins - genetics | Mast Cells - immunology | Receptor, Epidermal Growth Factor - immunology | Peptide Fragments - administration & dosage | Glycoproteins - antagonists & inhibitors | Intercellular Signaling Peptides and Proteins - genetics | Melanoma, Experimental - pathology | Antibodies, Neutralizing - pharmacology | Membrane Proteins - immunology | Mice, Transgenic | Forkhead Transcription Factors - genetics | Mast Cells - drug effects | Homeodomain Proteins - genetics | Gene Expression Regulation - drug effects | Membrane Proteins - administration & dosage | Glycoproteins - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Melanoma, Experimental - genetics | Signal Transduction - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Lymphocyte Activation - drug effects | Colitis - metabolism | Mice | Intercellular Signaling Peptides and Proteins - immunology | Epidermal growth factor | Universities and colleges | T cells | Analysis | Vaccination | Cells | Flow cytometry | Cytokines | Cloning | Melanoma | Kinases | Experiments | Cancer therapies | Rodents | Bone marrow | Software | Tumors | Cancer
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 2012, Volume 287, Issue 36, pp. 30610 - 30624
Journal Article