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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 34, pp. 15140 - 15144
Between the genetic extremes of rare monogenic and common polygenic diseases lie diverse oligogenic disorders involving mutations in more than one locus in... 
Deficiency diseases | Sex hormones | Nervous system diseases | Disease models | Medical genetics | Genetic diseases | Genetic mutation | Kallmann syndrome | Human genetics | Hypogonadism | Rare variant | Digenic | Idiopathic hypogonadotropic hypogonadism | FGFR1 | idiopathic hypogonadotropic hypogonadism | GPR54 | MULTIDISCIPLINARY SCIENCES | CLINICAL HETEROGENEITY | MISSENSE MUTATIONS | PUBERTY | digenic | GENE | BARDET-BIEDL-SYNDROME | LINKED KALLMANN-SYNDROME | FIBROBLAST-GROWTH-FACTOR-RECEPTOR-1 | GNRH RECEPTOR | rare variant | Receptors, LHRH - genetics | Humans | Male | Gene Regulatory Networks | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Case-Control Studies | Receptors, Peptide - genetics | Genetic Variation | DNA Mutational Analysis | Female | Neuropeptides - genetics | Fibroblast Growth Factor 8 - genetics | Kallmann Syndrome - genetics | Extracellular Matrix Proteins - genetics | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Hypogonadism - genetics | Homozygote | Phenotype | Pedigree | Gastrointestinal Hormones - genetics | Heterozygote | Models, Genetic | Receptors, G-Protein-Coupled - genetics | Mutation | Receptors, Kisspeptin-1 | Gonadotropin-Releasing Hormone - deficiency | Cohort Studies | Multifactorial diseases | Genetic aspects | Hormones | Gonadotropin | Health aspects | Pathogens | Genetics | Genetic disorders | Pathogenesis | Index Medicus | Biological Sciences
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2011, Volume 364, Issue 3, pp. 215 - 225
Journal Article
Genetics, ISSN 0016-6731, 10/2015, Volume 201, Issue 2, pp. 665 - 683
Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 12/2013, Volume 27, Issue 6, pp. 672 - 680
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2015, Volume 35, Issue 14, pp. 5435 - 5441
The lateral hypothalamus (LH) is a key regulator of multiple vital behaviors. The firing of brain-wide-projecting LH neurons releases neuropeptides promoting... 
GABA | Optogenetics | Hypothalamus | Melanin-concentrating hormone | Hypocretin | Orexin | SLEEP | optogenetics | melanin-concentrating hormone | NEUROSCIENCES | VENTRAL TEGMENTAL AREA | HISTAMINE NEURONS | HYPOCRETIN/OREXIN | NARCOLEPSY | hypocretin | MICE | orexin | RAT-BRAIN | hypothalamus | IN-SITU | Hypothalamic Area, Lateral - metabolism | Calcium - metabolism | gamma-Aminobutyric Acid - metabolism | Channelrhodopsins | Hypothalamic Area, Lateral - cytology | Intracellular Signaling Peptides and Proteins - metabolism | Melanins - metabolism | Nerve Net - physiology | Neural Inhibition - physiology | Neuropeptides - pharmacology | Neurons - physiology | Pituitary Hormones - metabolism | Lysine - metabolism | Neuropeptides - genetics | Intracellular Signaling Peptides and Proteins - genetics | Membrane Potentials - drug effects | Lysine - analogs & derivatives | Transduction, Genetic | Orexins | Neuropeptides - metabolism | Excitatory Amino Acid Antagonists - pharmacology | Melanins - genetics | Membrane Potentials - physiology | Patch-Clamp Techniques | Animals | Hypothalamic Hormones - metabolism | Pituitary Hormones - genetics | Luminescent Proteins - genetics | Signal Transduction - physiology | Hypothalamic Hormones - genetics | Mice | In Vitro Techniques | Neural Inhibition - drug effects | Luminescent Proteins - metabolism | Index Medicus | Brief Communications
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, pp. e101702 - e101702
Journal Article