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Science, ISSN 0036-8075, 11/2011, Volume 334, Issue 6058, pp. 941 - 948
Protein synthesis in all organisms is catalyzed by ribosomes. In comparison to their prokaryotic counterparts, eukaryotic ribosomes are considerably larger and... 
Proteins | Yeasts | RESEARCH ARTICLE | RNA | Ribosomal proteins | Antibiotics | Protein synthesis | Ribosomes | Tunnels | Transfer RNA | Crystal structure | CYCLOHEXIMIDE RESISTANCE | EXIT TUNNEL | YEAST | BLACKFAN ANEMIA | PROTEIN | MESSENGER-RNA | MULTIDISCIPLINARY SCIENCES | SHWACHMAN-DIAMOND SYNDROME | TRANSLATION ELONGATION | TRANSFER-RNA | 80S RIBOSOME | Ribosomal Proteins - chemistry | Ribosome Subunits, Large, Eukaryotic - ultrastructure | RNA, Ribosomal, 5.8S - chemistry | Tetrahymena thermophila - chemistry | Molecular Sequence Data | Crystallography, X-Ray | RNA, Ribosomal, 5.8S - metabolism | Peptide Chain Initiation, Translational | Ribosomal Proteins - metabolism | Protozoan Proteins - metabolism | Ribosome Subunits, Large, Eukaryotic - metabolism | Base Sequence | Protozoan Proteins - chemistry | Nucleic Acid Conformation | Binding Sites | Eukaryotic Initiation Factors - chemistry | Eukaryotic Initiation Factors - metabolism | Protein Structure, Secondary | Ribosome Subunits, Large, Eukaryotic - chemistry | Tetrahymena thermophila - metabolism | RNA, Ribosomal - chemistry | Crystallization | Models, Molecular | RNA, Ribosomal - metabolism | Anti-Bacterial Agents - metabolism | Cycloheximide - metabolism | RNA, Protozoan - chemistry | RNA, Protozoan - metabolism | Protein Conformation | Physiological aspects | Protein biosynthesis | Research | Structure | Ribonucleic acid--RNA | Eukaryotes
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2015, Volume 57, Issue 6, pp. 1074 - 1087
The eIF4E-binding proteins (4E-BPs) represent a diverse class of translation inhibitors that are often deregulated in cancer cells. 4E-BPs inhibit translation... 
STRUCTURAL INSIGHTS | COMPLEX | MECHANISM | PHOSPHORYLATION | MESSENGER-RNA CAP | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR 4E | INITIATION-FACTOR EIF4E | REPRESSOR 4E-BP2 | 4E-BINDING PROTEIN | REVEALS | CELL BIOLOGY | Adaptor Proteins, Signal Transducing - chemistry | Phosphorylation | Humans | Eukaryotic Initiation Factor-4E - metabolism | Crystallography, X-Ray | Intracellular Signaling Peptides and Proteins - metabolism | Eukaryotic Initiation Factor-4G - metabolism | Drosophila Proteins - metabolism | Phosphoproteins - metabolism | Phosphoproteins - chemistry | Peptide Initiation Factors - chemistry | Molecular Mimicry | Carrier Proteins - chemistry | Binding Sites | Intracellular Signaling Peptides and Proteins - genetics | Binding, Competitive | Recombinant Proteins - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Drosophila Proteins - chemistry | Amino Acid Motifs | Peptide Initiation Factors - metabolism | Carrier Proteins - genetics | Peptide Initiation Factors - genetics | Eukaryotic Initiation Factor-4E - chemistry | Animals | Carrier Proteins - metabolism | Intracellular Signaling Peptides and Proteins - chemistry | Protein Conformation | Eukaryotic Initiation Factor-4G - chemistry | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Binding proteins | Protein binding | Developmental biology
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 09/2018, Volume 38, Issue 18
Translation initiation of most mRNAs involves m7G-cap binding, ribosomal scanning, and AUG selection. Initiation from an m7G-cap-proximal AUG can be bypassed... 
Leaky scanning | TISU | EIF4E | Translation initiation | EIF1 | EIF4G1 | eIF1 | eIF4E | eIF4G1 | COMPLEX | 40S RIBOSOMAL-SUBUNIT | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | translation initiation | CELL BIOLOGY | MESSENGER-RNAS | ALLOSTERIC MECHANISM | AUG SELECTION | UPSTREAM AUG | START CODON SELECTION | IN-VIVO | BINDING | leaky scanning | Humans | Eukaryotic Initiation Factor-4E - metabolism | Ribosomes - metabolism | Peptide Chain Initiation, Translational | Eukaryotic Initiation Factor-4G - metabolism | Neoplasm Proteins - metabolism | RNA Caps - metabolism | RNA, Messenger - metabolism | Nerve Tissue Proteins - chemistry | HEK293 Cells | Eukaryotic Initiation Factor-1 - chemistry | Protein Interaction Domains and Motifs | Eukaryotic Initiation Factor-1 - metabolism | Neoplasm Proteins - genetics | Binding Sites | Eukaryotic Initiation Factor-4E - genetics | RNA Caps - genetics | Eukaryotic Initiation Factors - chemistry | Eukaryotic Initiation Factors - genetics | Eukaryotic Initiation Factors - metabolism | Amino Acid Sequence | RNA, Messenger - genetics | Eukaryotic Initiation Factor-1 - genetics | Models, Molecular | Neoplasm Proteins - chemistry | Saccharomyces cerevisiae Proteins - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Eukaryotic Initiation Factor-4E - chemistry | 5' Untranslated Regions | Models, Biological | Saccharomyces cerevisiae Proteins - metabolism | Eukaryotic Initiation Factor-4G - chemistry | Eukaryotic Initiation Factor-4G - genetics | Saccharomyces cerevisiae Proteins - chemistry
Journal Article
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2017, Volume 25, Issue 21, pp. 5904 - 5916
Journal Article