X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (25943) 25943
Publication (4605) 4605
Book Review (361) 361
Newspaper Article (228) 228
Newsletter (216) 216
Book Chapter (167) 167
Book / eBook (145) 145
Conference Proceeding (47) 47
Patent (46) 46
Dissertation (12) 12
Data Set (4) 4
Magazine Article (2) 2
Paper (2) 2
Government Document (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (13806) 13806
index medicus (13074) 13074
humans (9593) 9593
male (5903) 5903
biochemistry & molecular biology (5454) 5454
mice (5236) 5236
lipids (4624) 4624
rats (4484) 4484
peptides (4389) 4389
proteins (4240) 4240
research (3897) 3897
female (3404) 3404
research article (3377) 3377
physiological aspects (3218) 3218
cell biology (3013) 3013
molecular sequence data (2870) 2870
amino acid sequence (2765) 2765
gene expression (2734) 2734
nitric-oxide synthase (2734) 2734
multidisciplinary sciences (2631) 2631
expression (2568) 2568
nitric oxide (2509) 2509
medicine (2504) 2504
neurosciences (2493) 2493
signal transduction (2351) 2351
phosphorylation (2342) 2342
article (2295) 2295
enzymes (2246) 2246
metabolism (2226) 2226
analysis (2221) 2221
cells, cultured (2150) 2150
biosynthesis (2080) 2080
peptide synthases - metabolism (2039) 2039
science (2012) 2012
physiology (2002) 2002
biochemistry (1920) 1920
microbiology (1912) 1912
biology (1891) 1891
rodents (1874) 1874
genetic aspects (1798) 1798
inflammation (1793) 1793
oxidative stress (1789) 1789
pharmacology & pharmacy (1777) 1777
apoptosis (1629) 1629
rats, sprague-dawley (1590) 1590
endocrinology & metabolism (1544) 1544
activation (1533) 1533
kinases (1496) 1496
mice, inbred c57bl (1483) 1483
nitric oxide - metabolism (1422) 1422
genes (1409) 1409
health aspects (1408) 1408
alzheimer's disease (1391) 1391
disease models, animal (1366) 1366
gene-expression (1328) 1328
cells (1323) 1323
mutation (1304) 1304
cell line (1298) 1298
peptide synthases - genetics (1280) 1280
protein binding (1277) 1277
enzyme inhibitors - pharmacology (1219) 1219
escherichia-coli (1218) 1218
immunology (1193) 1193
rats, wistar (1167) 1167
kinetics (1163) 1163
biotechnology & applied microbiology (1149) 1149
identification (1149) 1149
protein (1126) 1126
immunohistochemistry (1096) 1096
nitric-oxide (1086) 1086
in-vivo (1069) 1069
inhibition (1063) 1063
binding sites (1058) 1058
brain (1056) 1056
rna, messenger - metabolism (1053) 1053
dose-response relationship, drug (1025) 1025
studies (1023) 1023
nitric oxide synthase - metabolism (1021) 1021
medicine, research & experimental (1019) 1019
review (1002) 1002
middle aged (988) 988
signal transduction - drug effects (985) 985
mice, knockout (975) 975
in-vitro (972) 972
blotting, western (971) 971
fatty acids (968) 968
peptides - metabolism (965) 965
life sciences (963) 963
amino acids (958) 958
base sequence (957) 957
alzheimers-disease (954) 954
mass spectrometry (953) 953
cell line, tumor (950) 950
adult (949) 949
diabetes (930) 930
cancer (923) 923
time factors (922) 922
bacterial proteins - metabolism (921) 921
amyloid beta-peptides - metabolism (908) 908
bacteria (904) 904
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (90) 90
UofT at Mississauga - Stacks (14) 14
Collection Dvlpm't (Acquisitions) - Closed Orders (8) 8
Collection Dvlpm't (Acquisitions) - Vendor file (8) 8
Chemistry (A D Allen) - Stacks (6) 6
UofT at Scarborough - Stacks (6) 6
UTL at Downsview - May be requested (3) 3
Engineering & Comp. Sci. - Stacks (2) 2
Online Resources - Online (2) 2
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Dentistry (Harry R Abbott) - May be requested in 6-10 wks (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Gerstein Science - Circulation Desk (1) 1
Law (Bora Laskin) - Stacks (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
Trinity College (John W Graham) - Stacks (1) 1
UofT at Mississauga - Reference (1) 1
UofT at Scarborough - Withdrawn (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (26496) 26496
Chinese (65) 65
Japanese (38) 38
French (32) 32
Russian (27) 27
German (25) 25
Spanish (18) 18
Polish (6) 6
Portuguese (5) 5
Hungarian (3) 3
Italian (2) 2
Korean (2) 2
Czech (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Chemical Biology, ISSN 1552-4450, 09/2015, Volume 11, Issue 9, pp. 705 - 712
Actin-targeting macrolides comprise a large, structurally diverse group of cytotoxins isolated from remarkably dissimilar micro- and macroorganisms. In spite... 
BACTERIAL SYMBIONT | GENE-CLUSTER | CYTOTOXIC MACROLIDES | NATURAL-PRODUCT DISCOVERY | CYANOBACTERIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYNTHASES | IN-SITU HYBRIDIZATION | SPONGE THEONELLA-SWINHOEI | IDENTIFICATION | ANTIFUNGAL MACROLIDE | Cyanobacteria - genetics | Deltaproteobacteria - metabolism | Multigene Family | Peptides | Actins - metabolism | Bacterial Proteins - chemistry | Cyanobacteria - metabolism | Molecular Sequence Data | Polyketides - chemistry | Small Molecule Libraries - metabolism | Polyketides - metabolism | Polyketide Synthases - metabolism | Macrolides - chemistry | Pyrans - chemistry | Pyrans - metabolism | Base Sequence | Actins - chemistry | Symbiosis | Gene Expression | Bacterial Proteins - genetics | Macrolides - metabolism | Biological Evolution | Small Molecule Libraries - chemistry | Polyketide Synthases - chemistry | Animals | Deltaproteobacteria - genetics | Theonella - microbiology | Protein Binding | Bacterial Proteins - metabolism | Polyketide Synthases - genetics | Enzymes | Bacteria | Biosynthesis | Metabolism | Polyketide Synthases/metabolism | Actins/metabolism | Macrolides/chemistry | Polyketide Synthases/chemistry | Life Sciences | Cyanobacteria/metabolism | Deltaproteobacteria/genetics | Bacterial Proteins/chemistry | Macrolides/metabolism | Actins/chemistry | Polyketide Synthases/genetics | Deltaproteobacteria/metabolism | Small Molecule Libraries/metabolism | Theonella/microbiology | Cyanobacteria/genetics | Pyrans/metabolism | Small Molecule Libraries/chemistry | Microbiology and Parasitology | Bacterial Proteins/metabolism | Polyketides/chemistry | Polyketides/metabolism | Bacterial Proteins/genetics | Pyrans/chemistry
Journal Article
Science, ISSN 0036-8075, 10/2009, Volume 326, Issue 5952, pp. 589 - 592
Journal Article
Biochemistry, ISSN 0006-2960, 06/2014, Volume 53, Issue 23, pp. 3796 - 3806
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e34064
New bioinformatic tools are needed to analyze the growing volume of DNA sequence data. This is especially true in the case of secondary metabolite... 
SILICO PREDICTION | COMPLETE GENOME SEQUENCE | EVOLUTION | NONRIBOSOMAL PEPTIDE SYNTHETASES | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | I POLYKETIDE SYNTHASES | CONDENSATION DOMAINS | BACTERIAL | MULTIPLE SEQUENCE ALIGNMENT | Computers | Protein Structure, Tertiary | Computational Biology - methods | Markov Chains | Soil Microbiology | Peptide Biosynthesis, Nucleic Acid-Independent | Phylogeny | Sequence Analysis, DNA | Peptide Synthases - genetics | Peptide Synthases - metabolism | Genetic Variation | Streptomyces - metabolism | Likelihood Functions | Polyketide Synthases - metabolism | Internet | Genome | Polyketide Synthases - genetics | Peptides | Web site management software | Ligases | Genes | DNA | Amino acids | Nucleotide sequencing | Product introduction | Plant metabolites | DNA sequencing | Cluster analysis | Biotechnology | Genomics | Biosynthesis | Genomes | Oceanography | Biodiversity | Condensation | Data bases | Gene sequencing | Datasets | Secondary metabolites | Databases | Metabolites | Condensates | Classification | Phylogenetics | Bacteria | Bioinformatics | Tags | Deoxyribonucleic acid--DNA | Assembly lines | Enzymes | Polypeptides | Nucleotide sequence | Marine biology | Metabolism | Polyketide synthase | Antibiotics | Natural products | Data sets | Deoxyribonucleic acid | Biological diversity
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2013, Volume 169, Issue 4, pp. 922 - 932
Background and Purpose Hydrogen sulfide (H2S) is a signalling molecule that belongs to the gasotransmitter family. Two major sources for endogenous enzymatic... 
DL‐propargylglycine | nitric oxide | hydrogen sulfide | cystathionine γ‐lyase | pyridoxal‐5′‐phosphate | cystathionine β‐synthase | aminooxyacetic acid | β‐cyano‐L‐alanine | cystathionine γ-lyase | DL-propargylglycine | cystathionine β-synthase | β-cyano-L-alanine | pyridoxal-5′-phosphate | Hydrogen Sulfide - metabolism | Glycine - analogs & derivatives | Cystathionine beta-Synthase - antagonists & inhibitors | Humans | Cystathionine gamma-Lyase - metabolism | Recombinant Fusion Proteins - metabolism | Alanine - analogs & derivatives | Glutathione Transferase - genetics | Alkynes - pharmacology | Aorta, Thoracic - drug effects | Cystathionine gamma-Lyase - genetics | Nitric Oxide Donors - pharmacology | Cystathionine beta-Synthase - genetics | Peptide Fragments - genetics | Alanine - pharmacology | Peptide Fragments - metabolism | Enzyme Inhibitors - pharmacology | Aorta, Thoracic - metabolism | Glutathione Transferase - metabolism | Rats | Cystathionine beta-Synthase - metabolism | Recombinant Fusion Proteins - chemistry | Glutathione Transferase - chemistry | Cystathionine gamma-Lyase - antagonists & inhibitors | Rats, Sprague-Dawley | Hydrogen Sulfide - analysis | Aorta, Thoracic - enzymology | Animals | Glycine - pharmacology | Kinetics | Vasodilation - drug effects | In Vitro Techniques | Nitric Oxide - metabolism | Research Papers
Journal Article