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JAMA : the journal of the American Medical Association, ISSN 0098-7484, 05/2014, Volume 311, Issue 18, pp. 1870 - 1882
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 2, pp. E156 - E165
Current treatments to control pathological or unwanted immune responses often use broadly immunosuppressive drugs. New approaches to induce antigen-specific... 
Nanoparticles | Rapamycin | Anti-drug antibodies | Immune tolerance | Immunotherapy | THERAPEUTICS | anti-drug antibodies | IMMUNITY | TOLEROGENIC DENDRITIC CELLS | RISK-FACTORS | MULTIDISCIPLINARY SCIENCES | FACTOR-VIII | MECHANISMS | RESPONSES | immune tolerance | IMMUNOGENICITY | nanoparticles | UNRESPONSIVENESS | immunotherapy | rapamycin | Factor VIII - immunology | Oligodeoxyribonucleotides - administration & dosage | Nanoparticles - chemistry | Ovalbumin - immunology | Immunosuppression - methods | Nanocapsules - administration & dosage | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Hypersensitivity, Delayed - immunology | Nanocapsules - chemistry | Peptides - administration & dosage | Antigens - administration & dosage | CD4-Positive T-Lymphocytes - immunology | Immunity, Humoral | Peptide Fragments - immunology | Proteins - administration & dosage | Female | Immunosuppressive Agents - administration & dosage | Disease Models, Animal | Lactic Acid - chemistry | Peptides - chemistry | Hemophilia A - immunology | Peptide Fragments - administration & dosage | Peptides - immunology | Immune Tolerance | Hemophilia A - therapy | Hypersensitivity, Delayed - therapy | Antigens - chemistry | Proteins - immunology | Encephalomyelitis, Autoimmune, Experimental - therapy | Sirolimus - administration & dosage | Animals | Ovalbumin - administration & dosage | Recombinant Proteins - immunology | Polyglycolic Acid - chemistry | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Hemocyanins - administration & dosage | Proteins - chemistry | Antigens | Usage | Research | Health aspects | Immunological tolerance | Immunological research | Biological Sciences | PNAS Plus
Journal Article
Diabetes care, ISSN 1935-5548, 2018, Volume 41, Issue 8, pp. 1543 - 1556
.... Food and Drug Administration-approved glucose-lowering agents, keen personalized management in T2D has become a challenge for health care providers in daily practice... 
Humans | Insulin/administration & dosage | Treatment Outcome | Dipeptidyl-Peptidase IV Inhibitors/administration & dosage | Sodium-Glucose Transporter 2/antagonists & inhibitors | Hypoglycemic Agents/administration & dosage | Signal Transduction/drug effects | Metformin/administration & dosage | Animals | Diabetes Mellitus, Type 2/drug therapy | Blood Glucose/drug effects | Thiazolidinediones/administration & dosage | Sulfonylurea Compounds/administration & dosage | Drug Therapy, Combination | KIDNEY-DISEASE | GLUCOSE COTRANSPORTER 2 | ADD-ON THERAPY | DIPEPTIDYL PEPTIDASE-4 INHIBITORS | GLYCEMIC CONTROL | GLP-1 RECEPTOR AGONISTS | GLUCAGON-LIKE PEPTIDE-1 | CARDIOVASCULAR OUTCOMES | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | METFORMIN PLUS SULFONYLUREA | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Insulin - administration & dosage | Sodium-Glucose Transporter 2 Inhibitors | Sulfonylurea Compounds - adverse effects | Thiazolidinediones - administration & dosage | Thiazolidinediones - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - administration & dosage | Metformin - adverse effects | Blood Glucose - drug effects | Hypoglycemic Agents - administration & dosage | Signal Transduction - drug effects | Sulfonylurea Compounds - administration & dosage | Metformin - administration & dosage | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Type 2 diabetes | Usage | Analysis | Practice guidelines (Medicine) | Hypoglycemic agents | Dosage and administration | Drug therapy, Combination | Drug therapy | Risk factors
Journal Article
Chest, ISSN 0012-3692, 2012, Volume 141, Issue 2, pp. e24S - e43S
This article describes the pharmacology of approved parenteral anticoagulants. These include the indirect anticoagulants, unfractionated heparin (UFH),... 
RESPIRATORY SYSTEM | LOW-MOLECULAR-WEIGHT | ACUTE MYOCARDIAL-INFARCTION | DEEP-VEIN THROMBOSIS | HEPARIN-INDUCED THROMBOCYTOPENIA | RECOMBINANT FACTOR VIIA | PATHOLOGISTS CONFERENCE XXXI | PARTIAL THROMBOPLASTIN TIME | ANTI-FACTOR-XA | ACUTE VENOUS THROMBOEMBOLISM | UNFRACTIONATED HEPARIN | CRITICAL CARE MEDICINE | Heparitin Sulfate - adverse effects | United States | Humans | Thrombin - antagonists & inhibitors | Heparin - administration & dosage | Heparin, Low-Molecular-Weight - adverse effects | Recombinant Proteins - adverse effects | Heparin - adverse effects | Hirudins - administration & dosage | Dose-Response Relationship, Drug | Pipecolic Acids - administration & dosage | Chondroitin Sulfates - adverse effects | Societies, Medical | Pipecolic Acids - adverse effects | Heparitin Sulfate - administration & dosage | Polysaccharides - administration & dosage | Thrombosis - blood | Thrombosis - prevention & control | Dermatan Sulfate - administration & dosage | Dermatan Sulfate - adverse effects | Peptide Fragments - administration & dosage | Polysaccharides - adverse effects | Evidence-Based Medicine | Recombinant Proteins - administration & dosage | Antithrombins - agonists | Chondroitin Sulfates - administration & dosage | Hirudins - adverse effects | Fibrinolytic Agents - administration & dosage | Peptide Fragments - adverse effects | Thrombosis - drug therapy | Heparin, Low-Molecular-Weight - administration & dosage | Infusions, Intravenous | Practice Guidelines as Topic | Antithrombotic Therapy and Prevention of Thrombosis, 9th Ed | American College of Chest Physician Evidence-Based Clinical Practice Guidelines Online Only
Journal Article
Diabetes care, ISSN 1935-5548, 2014, Volume 37, Issue 8, pp. 2317 - 2325
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2010, Volume 376, Issue 9739, pp. 431 - 439
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 08/2012, Volume 161, Issue 3, pp. 735 - 745
The objective of the present study was to investigate the effect of polyarginine chain length on topical delivery of surface modified NLCs. Design of... 
Nanostructured lipid carriers (NLC) | Cell penetrating peptide (CPP) | Polyarginine peptide | Skin delivery | Allergic contact dermatitis (ACD) | DRUG-DELIVERY | CHITOSAN CROSS-LINKING | TRANSDERMAL DELIVERY | MEFLOQUINE HYDROCHLORIDE MICROPARTICLES | CELL-PENETRATING PEPTIDES | TACROLIMUS OINTMENT | CHEMISTRY, MULTIDISCIPLINARY | DERMAL DELIVERY | PHARMACOLOGY & PHARMACY | H-II MESOPHASES | SUBSTANCE-P | SPANTIDE-II | Nanoparticles - chemistry | Drug Carriers - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Drug Carriers - chemistry | Peptides - administration & dosage | Ketoprofen - chemistry | Allergens - administration & dosage | Lipids - chemistry | Rats, Hairless | Skin Absorption - drug effects | Substance P - analogs & derivatives | Oligopeptides - chemistry | Cell-Penetrating Peptides - chemistry | Dermatitis, Allergic Contact - drug therapy | Peptides - chemistry | Mice, Inbred C57BL | Ketoprofen - administration & dosage | Rats | Lipids - administration & dosage | Dinitrofluorobenzene - administration & dosage | Animals | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Mice | Nanoparticles - administration & dosage | Oligopeptides - administration & dosage | Cell-Penetrating Peptides - administration & dosage | Administration, Topical | Substance P - chemistry | Substance P - administration & dosage | Usage | Peptides | Dermatology | Analysis | Formulae, receipts, prescriptions | Dermatologic agents | Skin | Raman spectroscopy | Transdermal medication | polyarginine peptide | cell penetrating peptide (CPP) | nanostructured lipid carriers (NLC) | allergic contact dermatitis (ACD)
Journal Article
Advanced drug delivery reviews, ISSN 0169-409X, 2013, Volume 65, Issue 6, pp. 782 - 799
Among 12billion injections administered annually, unsafe delivery leads to >20million infections and >100million reactions. In an emerging new concept,... 
Molecular farming | Infectious diseases | Bioencapsulation | Hemophilia | Oral vaccines | Autoantigens | Diabetes | Lyophilization | TOXIN-B-SUBUNIT | APICAL MEMBRANE ANTIGEN-1 | HEAT-LABILE ENTEROTOXIN | ESCHERICHIA-COLI | MEROZOITE SURFACE PROTEIN-1 | YERSINIA-PESTIS | TRANSGENIC CHLOROPLASTS | FUSION PROTEIN | PHARMACOLOGY & PHARMACY | NASAL DRUG-DELIVERY | CHOLERA-TOXIN | Factor IX - administration & dosage | Proteins - pharmacokinetics | Administration, Oral | Humans | Vaccines - pharmacokinetics | Freeze Drying | Autoantigens - administration & dosage | Biological Availability | Blood Glucose | Plant Cells | Exenatide | Gastrointestinal Tract - metabolism | Peptides - administration & dosage | Drug Carriers | Plague Vaccine - administration & dosage | Diabetes Mellitus - prevention & control | Malaria Vaccines - administration & dosage | Diabetes Mellitus - therapy | Proteins - administration & dosage | Venoms - administration & dosage | Cholera Vaccines - administration & dosage | Proinsulin - administration & dosage | Vaccines - administration & dosage | Autoimmunity | Glucagon | Dendritic cells | Blood sugar | Biological products industry | Vaccines | Glutamate | Prothrombin complex concentrate | Biopharmaceutics | Proteins | Prevention | Glucose metabolism | Type 1 diabetes | Gastrointestinal system | Cholera toxin | Health aspects | Acids | hemophilia | lyophilization | molecular farming | infectious diseases | bioencapsulation | oral vaccines | diabetes
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 07/2009, Volume 157, Issue 5, pp. 831 - 843
Background and purpose:  Buprenorphine displays attributes of opioids, but also some features distinct from them. We examined spinal and supraspinal signal... 
mechanism of action | supraspinal | buprenorphine | analgesia (antinociception) | Supraspinal | Analgesia (antinociception) | Buprenorphine | Mechanism of action | OKADAIC-ACID | MU-OPIOID RECEPTOR | INTRINSIC EFFICACY | MOLECULAR-REARRANGEMENTS | SERINE/THREONINE PROTEIN PHOSPHATASES | PARTIAL AGONIST | ORL1 RECEPTOR | PHARMACOLOGY & PHARMACY | MORPHINE-THEBAINE GROUP | TAIL-FLICK TEST | INDUCED ANTINOCICEPTION | Fentanyl - administration & dosage | Piperazines - administration & dosage | Narcotic Antagonists - administration & dosage | Serotonin Antagonists - administration & dosage | Phosphoprotein Phosphatases - metabolism | Aminoquinolines - administration & dosage | Injections, Intraventricular | Oligonucleotides, Antisense - metabolism | Male | Opioid Peptides - administration & dosage | Pain - chemically induced | Adrenergic alpha-Antagonists - administration & dosage | Pain - metabolism | GTP-Binding Proteins - genetics | Okadaic Acid - administration & dosage | Brain - metabolism | Dose-Response Relationship, Drug | Enzyme Inhibitors - administration & dosage | Benzamides - administration & dosage | Pain Threshold - drug effects | Anesthetics, Local - administration & dosage | Pertussis Toxin - administration & dosage | Receptor, Serotonin, 5-HT1A - metabolism | Disease Models, Animal | Receptors, Opioid - metabolism | Injections, Spinal | Pyridines - administration & dosage | Pain - prevention & control | Phosphoprotein Phosphatases - antagonists & inhibitors | Yohimbine - administration & dosage | Brain - drug effects | Buprenorphine - administration & dosage | Animals | Signal Transduction - drug effects | Analgesics, Opioid - administration & dosage | Acetylcholine | Mice | Naloxone - administration & dosage | Pain Measurement | Morphine - administration & dosage | Receptors, Opioid - drug effects | Serotonin 5-HT1 Receptor Antagonists | GTP-Binding Proteins - metabolism | Index Medicus | Research Papers
Journal Article