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1. Full Text Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
by Shi, Min and Bradner, Joshua and Hancock, Aneeka M and Chung, Kathryn A and Quinn, Joseph F and Peskind, Elaine R and Galasko, Douglas and Jankovic, Joseph and Zabetian, Cyrus P and Kim, Hojoong M and Leverenz, James B and Montine, Thomas J and Ginghina, Carmen and Kang, Un Jung and Cain, Kevin C and Wang, Yu and Aasly, Jan and Goldstein, David and Zhang, Jing
Annals of Neurology, ISSN 0364-5134, 03/2011, Volume 69, Issue 3, pp. 570 - 580
Objective: There is a clear need to develop biomarkers for Parkinson disease (PD) diagnosis, differential diagnosis of Parkinsonian disorders, and monitoring... 
TAU-PROTEIN | MULTIPLE SYSTEM ATROPHY | DEMENTIA | MICROGLIA | ALZHEIMERS-DISEASE | INFLAMMATION | CSF | ALPHA-SYNUCLEIN | FRACTALKINE-RECEPTOR | NEUROSCIENCES | LEWY BODIES | CLINICAL NEUROLOGY | Severity of Illness Index | Diagnosis, Differential | Phosphorylation | Peptide Fragments - cerebrospinal fluid | Intracellular Signaling Peptides and Proteins - cerebrospinal fluid | Humans | Chemokine CX3CL1 - cerebrospinal fluid | tau Proteins - cerebrospinal fluid | fms-Like Tyrosine Kinase 3 - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Disease Progression | Alzheimer Disease - diagnosis | Protein Deglycase DJ-1 | Multiple System Atrophy - cerebrospinal fluid | alpha-Synuclein - cerebrospinal fluid | Analysis of Variance | Parkinson Disease - cerebrospinal fluid | Sensitivity and Specificity | Amyloid beta-Peptides - cerebrospinal fluid | Parkinson Disease - diagnosis | ROC Curve | Biomarkers - cerebrospinal fluid | Multiple System Atrophy - diagnosis | Oncogene Proteins - cerebrospinal fluid | Biomarkers | Ligands | Parkinsons disease
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2. Full Text Cerebrospinal fluid secretion by the choroid plexus
by Damkier, Helle H and Brown, Peter D and Praetorius, Jeppe
Physiological Reviews, ISSN 0031-9333, 10/2013, Volume 93, Issue 4, pp. 1847 - 1892
The choroid plexus epithelium is a cuboidal cell monolayer, which produces the majority of the cerebrospinal fluid. The concerted action of a variety of... 
PHYSIOLOGY | ATRIAL-NATRIURETIC-PEPTIDE | ANGIOTENSIN CONVERTING ENZYME | TISSUE-SPECIFIC EXPRESSION | AQUAPORIN WATER CHANNELS | IDIOPATHIC INTRACRANIAL HYPERTENSION | VENTRICULAR CELL-MEMBRANE | TIGHT JUNCTION PROTEINS | NORMAL-PRESSURE HYDROCEPHALUS | BETA-SUBUNIT ISOFORMS | EPITHELIAL SODIUM-CHANNELS | Carrier Proteins - physiology | Choroid Plexus - secretion | Choroid Plexus - physiology | Water-Electrolyte Balance - physiology | Animals | Humans | Models, Animal | Cerebrospinal Fluid - secretion | Choroid plexus | Nervous system diseases | Osmoregulation | Causes of | Water-electrolyte balance (Physiology) | Cerebrospinal fluid | Research
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3. Full Text Expanding the cerebrospinal fluid endopeptidome
by Hansson, Karl T and Skillbäck, Tobias and Pernevik, Elin and Kern, Silke and Portelius, Erik and Höglund, Kina and Brinkmalm, Gunnar and Holmén‐Larsson, Jessica and Blennow, Kaj and Zetterberg, Henrik and Gobom, Johan and Centrum för åldrande och hälsa (AgeCap) and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy and Sahlgrenska akademin and Centre for Ageing and Health (Agecap)
PROTEOMICS, ISSN 1615-9853, 03/2017, Volume 17, Issue 5, pp. 1600384 - n/a
Biomarkers of neurodegenerative disorders are needed to assist in diagnosis, to monitor disease progression and therapeutic interventions, and to provide... 
Biomarkers | Cerebrospinal fluid | Peptidomics | Neurodegeneration | Alzheimer's disease | GENOTYPE | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | MARKERS | TAU | IDENTIFICATION | MASS-SPECTROMETRY | APOLIPOPROTEIN-E | SEQUENCE DATABASES | PEPTIDES | MASCOT | Humans | Software | Biomarkers - cerebrospinal fluid | Peptides - cerebrospinal fluid | Proteomics - methods | Cerebrospinal Fluid Proteins - analysis | Chromatography, Liquid - methods | Neurodegenerative Diseases - cerebrospinal fluid | Mass Spectrometry - methods | Nervous system diseases | Algorithms | Peptides | Analysis | Amyloid beta-protein | Development and progression | Apolipoproteins | Apolipoprotein E4 | Threonine | Neurodegenerative diseases | Therapeutic applications | Liquid chromatography | High-performance liquid chromatography | pH effects | Amyloid precursor protein | Proteins | Tau protein | Apolipoprotein E | Isoforms | pH | β-Amyloid | databases | Neurosciences | mascot | peptides | tau | apolipoprotein-e | tandem mass-spectrometry | genotype | sequence | Biochemistry & Molecular Biology | identification | Biokemi och molekylärbiologi | Biochemistry and Molecular Biology | Psykiatri | markers | Psychiatry | Neurovetenskaper | alzheimers-disease
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4. Full Text Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
by Blennow, Kaj and Hampel, Harald and Zetterberg, Henrik and Weiner, Michael and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Nature Reviews Neurology, ISSN 1759-4758, 03/2010, Volume 6, Issue 3, pp. 131 - 144
Intense multidisciplinary research has provided detailed knowledge of the molecular pathogenesis of Alzheimer disease (AD). This knowledge has been translated... 
ALPHA-SECRETASE | GAMMA-SECRETASE INHIBITOR | PHOSPHORYLATED TAU-PROTEIN | FRONTOTEMPORAL DEMENTIA | A-BETA | NEUROFIBRILLARY PATHOLOGY | CSF BIOMARKERS | AMYLOID PRECURSOR PROTEIN | MILD COGNITIVE IMPAIRMENT | CLINICAL NEUROLOGY | TRANSGENIC MICE | Cognition Disorders - cerebrospinal fluid | Alzheimer Disease - complications | Peptide Fragments - cerebrospinal fluid | Cognition Disorders - blood | Humans | tau Proteins - cerebrospinal fluid | Biomarkers - blood | Alzheimer Disease - cerebrospinal fluid | Amyloid beta-Peptides - blood | tau Proteins - blood | Animals | Cognition Disorders - etiology | Peptide Fragments - blood | Amyloid beta-Peptides - cerebrospinal fluid | Biomarkers - cerebrospinal fluid | Alzheimer Disease - blood | Usage | Physiological aspects | Genetic aspects | Diagnosis | Cerebrospinal fluid | Research | Biological markers | Alzheimer's disease | Blood plasma | Neurosciences | Peptide Fragments | complications | Biological Markers | Alzheimer Disease | blood | tau Proteins | Amyloid beta-Protein | etiology | Cognition Disorders | cerebrospinal fluid | Psykiatri | Psychiatry | Neurovetenskaper
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5. Full Text Effect of 1 Night of Total Sleep Deprivation on Cerebrospinal Fluid β-Amyloid 42 in Healthy Middle-Aged Men: A Randomized Clinical Trial
by Ooms, Sharon and Overeem, Sebastiaan and Besse, Kees and Rikkert, Marcel Olde and Verbeek, Marcel and Claassen, Jurgen A. H. R
JAMA Neurology, ISSN 2168-6149, 08/2014, Volume 71, Issue 8, pp. 971 - 977
IMPORTANCE: Increasing evidence suggests a relationship between poor sleep and the risk of developing Alzheimer disease. A previous study found an effect of... 
CLEARANCE | PEPTIDES | BIOMARKER | ALZHEIMERS-DISEASE | IN-VIVO | DYNAMICS | RISK | BRAIN | CLINICAL NEUROLOGY | WAKEFULNESS | Sleep Deprivation - cerebrospinal fluid | Peptide Fragments - cerebrospinal fluid | Time Factors | Humans | Middle Aged | Amyloid beta-Peptides - cerebrospinal fluid | Adult | Male | Sleep - physiology | Polysomnography
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6. Full Text Cerebrospinal fluid biomarkers in Parkinson disease
by Parnetti, L and Castrioto, A and Chiasserini, D and Persichetti, E and Tambasco, N and El-Agnaf, O and Calabresi, P
Nature Reviews Neurology, ISSN 1759-4758, 2013, Volume 9, Issue 3, pp. 131 - 140
Clinical diagnosis of Parkinson disease (PD) is difficult in early stages of disease, with high risk of misdiagnosis. The long preclinical phase of PD provides... 
TAU-PROTEIN | ALPHA-SYNUCLEIN OLIGOMERS | MULTIPLE SYSTEM ATROPHY | CSF AMYLOID-BETA | ALZHEIMERS-DISEASE | ELEVATED LEVELS | SOLUBLE OLIGOMERS | GLUCOCEREBROSIDASE MUTATIONS | LEWY BODIES | CLINICAL NEUROLOGY | CELL-DEATH | Protein Deglycase DJ-1 | Parkinson Disease - pathology | Intracellular Signaling Peptides and Proteins - cerebrospinal fluid | Humans | Parkinson Disease - cerebrospinal fluid | Amyloid beta-Peptides - cerebrospinal fluid | Parkinson Disease - diagnosis | Biomarkers - cerebrospinal fluid | Oncogene Proteins - cerebrospinal fluid | Intermediate Filament Proteins - cerebrospinal fluid | Disease Progression | Parkinson's disease | Analysis | Cerebrospinal fluid | Research | Diagnosis | Biological markers | Identification and classification
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7. Full Text Accuracy of Brain Amyloid Detection in Clinical Practice Using Cerebrospinal Fluid β-Amyloid 42: A Cross-Validation Study Against Amyloid Positron Emission Tomography
by Palmqvist, Sebastian and Zetterberg, Henrik and Blennow, Kaj and Vestberg, Susanna and Andreasson, Ulf and Brooks, David J and Owenius, Rikard and Hägerström, Douglas and Wollmer, Per and Minthon, Lennart and Hansson, Oskar and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
JAMA Neurology, ISSN 2168-6149, 10/2014, Volume 71, Issue 10, pp. 1282 - 1289
IMPORTANCE: Before adding cerebrospinal fluid (CSF) biomarkers to the diagnostic workup of Alzheimer disease, it needs to be determined whether CSF biomarkers... 
TAU-PROTEIN | DEMENTIA | DISCRIMINATION | ALZHEIMERS-DISEASE | DEPOSITION | MARKERS | CSF BIOMARKERS | MILD COGNITIVE IMPAIRMENT | ASSOCIATION | CLINICAL NEUROLOGY | PROSPECTIVE COHORT | Brain - diagnostic imaging | Aniline Compounds | Humans | Middle Aged | Gyrus Cinguli - diagnostic imaging | Male | Positron-Emission Tomography | Cerebral Cortex - metabolism | Alzheimer Disease - diagnosis | Brain - metabolism | Amyloid beta-Peptides - metabolism | Aged, 80 and over | Amyloid beta-Peptides - cerebrospinal fluid | Female | Cognitive Dysfunction - diagnosis | Cognitive Dysfunction - diagnostic imaging | Radiopharmaceuticals | Reproducibility of Results | Peptide Fragments - cerebrospinal fluid | Cross-Sectional Studies | Cognitive Dysfunction - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Cerebral Cortex - diagnostic imaging | Gyrus Cinguli - metabolism | Aged | Alzheimer Disease - diagnostic imaging | Early Diagnosis | Benzothiazoles | Cohort Studies | Neurosciences | Neurovetenskaper
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8. Full Text Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects
by Toledo, J.B and Zetterberg, H and van Harten, A.C and Glodzik, L and Martinez-Lage, P and Bocchio-Chiavetto, L and Rami, L and Hansson, O and Sperling, R and Engelborghs, S and Osorio, R.S and Vanderstichele, H and Vandijck, M and Hampel, H and Teipl, S and Moghekar, A and Albert, M and Hu, W.T and Argiles, J.A.M and Gorostidi, A and Teunissen, C.E and de Deyn, P.P and Hyman, B.T and Molinuevo, J.L and Frisoni, G. B and Linazasoro, G and de Leon, M.J and van der Flier, W.M and Scheltens, P and Blennow, K and Shaw, L.M and Trojanowski, J.Q and Alzheimer's Dis Neuroimaging and Alzheimer’s Disease Neuroimaging Initiative and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Brain, ISSN 0006-8950, 2015, Volume 138, Issue 9, pp. 2701 - 2715
In a large multicentre study, Toledo et al. examine core Alzheimer's disease CSF biomarkers in 1233 cognitively normal subjects aged 40-85 years. Alzheimer... 
dementia | cognitive ageing | Alzheimer's disease | imaging | biomarkers | ADULT LIFE-SPAN | ASSOCIATION GUIDELINES | CSF BIOMARKERS | 2 ANALYTICAL PLATFORMS | NEUROSCIENCES | CLINICAL NEUROLOGY | NEUROPATHOLOGIC ASSESSMENT | TAU PROTEINS | NATIONAL INSTITUTE | BETA-AMYLOID 1-42 | AGING BRAIN | AGE | Severity of Illness Index | Alzheimer Disease - physiopathology | Peptide Fragments - cerebrospinal fluid | Age Factors | Neurodegenerative Diseases - etiology | Humans | Middle Aged | Male | tau Proteins - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Neuropsychological Tests | Analysis of Variance | Apolipoproteins E - genetics | Aged, 80 and over | Amyloid beta-Peptides - cerebrospinal fluid | Cognition - physiology | Adult | Female | Aged | Alzheimer Disease - genetics | Cohort Studies | Neurosciences | Neurovetenskaper
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