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Proceedings of the National Academy of Sciences, ISSN 0027-8424, 05/2014, Volume 111, Issue 18, pp. E1909 - E1917
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, p. e0160973
This study demonstrates the effectiveness of a peptide shuttle in delivering diclofenac into and through human epidermis. Diclofenac was conjugated to a novel... 
HUMAN IMMUNODEFICIENCY VIRUS | IN-VITRO | POTENTIAL USE | SOLID-PHASE SYNTHESIS | MULTIDISCIPLINARY SCIENCES | TRANSDERMAL DELIVERY | 5-AMINOLEVULINIC ACID | H-II MESOPHASES | ACTINIC KERATOSES | BRAIN-BARRIER BBB | SODIUM DICLOFENAC | Diclofenac - pharmacology | Humans | Middle Aged | Piperazines - chemistry | Peptides, Cyclic - chemistry | Peptides, Cyclic - metabolism | Drug Carriers | Solid-Phase Synthesis Techniques | Gene Products, tat - metabolism | Cyclooxygenase 2 - genetics | Adult | Female | Dipeptides - metabolism | Epidermis - metabolism | Cyclooxygenase Inhibitors - metabolism | Gene Expression | Tissue Culture Techniques | Epidermis - drug effects | Gene Products, tat - chemistry | Permeability | Abdominoplasty | Dipeptides - chemistry | Cyclooxygenase Inhibitors - pharmacology | Diffusion Chambers, Culture | Cyclooxygenase 2 - metabolism | Diclofenac - metabolism | Actinic keratosis | Complications and side effects | Care and treatment | Analysis | Skin diseases | Dosage and administration | Research | Cells | Diclofenac | Peptides | Dermatology | Epidermis | Amino acids | Biopolymers | Chromatography | Nanoparticles | Studies | Shuttles | Penetration | Pharmacy | Skin | Diagnostic systems | Conjugation | Cyclooxygenase-2 | Nonsteroidal anti-inflammatory drugs | Pell | Peptide synthesis | Cromatografia de líquids d'alta resolució | Síntesi de pèptids | High performance liquid chromatography
Journal Article
Chemical Communications, ISSN 1359-7345, 08/2011, Volume 47, Issue 32, pp. 9218 - 9220
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 01/2014, Volume 73, Issue 1, pp. 263 - 269
Background Rheumatoid arthritis (RA) is characterised by autoimmunity to citrullinated proteins, and there is increasing epidemiologic evidence linking... 
Autoimmunity | BACTERIA | CITRULLINATED PROTEINS | Rheumatoid Arthritis | SERUM IGG ANTIBODIES | Ant-CCP | ALPHA | ENOLASE | RHEUMATOLOGY | CELIAC-DISEASE | PERIODONTITIS | TISSUE TRANSGLUTAMINASE | ASSOCIATION | Porphyromonas gingivalis - enzymology | Hydrolases - genetics | Periodontitis - microbiology | Humans | Citrulline - metabolism | Molecular Sequence Data | Male | Peptides, Cyclic - metabolism | Immune Tolerance - immunology | Mass Spectrometry | Peptides, Cyclic - genetics | Adult | Female | Bacteroidaceae Infections - metabolism | Porphyromonas gingivalis - immunology | Porphyromonas gingivalis - genetics | Amino Acid Sequence | Mutagenesis, Site-Directed | Periodontitis - immunology | Peptides, Cyclic - immunology | Arthritis, Rheumatoid - microbiology | Periodontitis - genetics | Arthritis, Rheumatoid - genetics | Autoantibodies - immunology | Bacteroidaceae Infections - microbiology | Bacteroidaceae Infections - immunology | Hydrolases - immunology | Immune Tolerance - genetics | Arthritis, Rheumatoid - immunology | Protein-Arginine Deiminases | Causes of | Immune response | Research | Bacterial proteins | Rheumatoid arthritis | Proteins | Studies | Enzymes | Immunoglobulins | Hypotheses | Bacterial infections | Biomedical research | Disease | Peptides | Scientific imaging | Localization | Binding sites | Basic and Translational Research | 1506
Journal Article
Current topics in medicinal chemistry, 2018, Volume 18, Issue 7, p. 525
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2017, Volume 292, Issue 24, pp. 10288 - 10294
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 12/2014, Volume 111, Issue 50, pp. 17863 - 17868
Integrin α5β1 binds to an Arg-Gly-Asp (RGD) motif in its ligand fibronectin. We report high-resolution crystal structures of a four-domain α5β1 headpiece... 
Calcium - metabolism | Crystallization | Models, Molecular | Ligands | Protein Conformation | Fluorescence Polarization | Fibronectins - metabolism | Integrin alpha5beta1 - chemistry | Integrin alpha5beta1 - metabolism | Peptides, Cyclic - metabolism | Biological Sciences
Journal Article
Amino Acids, ISSN 0939-4451, 11/2017, Volume 49, Issue 11, pp. 1867 - 1883
The transformation from normal to malignant phenotype in human cancers is associated with aberrant cell-surface glycosylation. Thus, targeting glycosylation... 
Biochemistry, general | Neurobiology | Glycosylation | Carbohydrate-binding protein | Life Sciences | Analytical Chemistry | Cyclic peptide | Life Sciences, general | Biochemical Engineering | Proteomics | Lectinomimics | Cell migration | Tumor metastasis | ANTIBODIES | ASPARTIMIDE FORMATION | ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CONFORMATION | LECTINS | MUC1 | IMPACT | PROTEINS | Neoplasms - metabolism | Peptidomimetics - chemical synthesis | Fucose - metabolism | Humans | Peptides, Cyclic - pharmacology | Structure-Activity Relationship | Peptides, Cyclic - chemistry | Peptides, Cyclic - metabolism | Drug Delivery Systems | Lectins - metabolism | MCF-7 Cells | Inhibitory Concentration 50 | Polysaccharides - chemistry | Protein Interaction Domains and Motifs | Lectins - chemistry | Binding, Competitive | Cell Line | Cell Survival - drug effects | Peptidomimetics - pharmacology | Peptidomimetics - metabolism | Fucose - agonists | Peptidomimetics - chemistry | Hep G2 Cells | Neoplasms - drug therapy | Polysaccharides - metabolism | Cell Movement - drug effects | Peptides, Cyclic - chemical synthesis | Protein Conformation | Molecular Docking Simulation | Neoplasms - pathology | Lactams - chemistry | Polysaccharides | Biological products | Peptides | Lectins | Metastasis | Biomedical engineering | Protein binding | Cancer | Transformation | Leukocyte migration | Amides | N-Acetyl-D-galactosamine | Cell surface | Metastases | L-fucose | Biomedical materials | D-Galactose | Carbohydrates | Breast cancer | Tumor cell lines | Glycan | Mucin | D-Galactosamine | Skin | Aberration | Galactose | Fucose | Conformation | cell migration | carbohydrate-binding protein | glycosylation | cyclic peptide | tumor metastasis | lectinomimics
Journal Article