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index medicus (332) 332
microbiology (292) 292
escherichia-coli (226) 226
biochemistry & molecular biology (197) 197
penicillin-binding proteins (177) 177
peptidoglycan (174) 174
peptidoglycan - metabolism (171) 171
bacterial proteins - metabolism (169) 169
bacteria (150) 150
cell wall - metabolism (143) 143
peptidoglycans (138) 138
biosynthesis (125) 125
proteins (125) 125
molecular sequence data (118) 118
physiological aspects (118) 118
bacterial proteins - genetics (114) 114
research (110) 110
escherichia coli - genetics (105) 105
peptidoglycan - biosynthesis (104) 104
peptidoglycan glycosyltransferase (104) 104
escherichia coli - metabolism (99) 99
peptidoglycan glycosyltransferase - metabolism (99) 99
amino acid sequence (98) 98
enzymes (97) 97
anti-bacterial agents - pharmacology (96) 96
bacterial proteins (95) 95
glycosyltransferases - metabolism (95) 95
escherichia coli proteins (93) 93
research article (93) 93
mutation (92) 92
cell division (91) 91
escherichia coli - enzymology (91) 91
analysis (89) 89
protein binding (88) 88
antibiotics (85) 85
escherichia coli (85) 85
penicillin-binding proteins - metabolism (84) 84
article (78) 78
bacillus-subtilis (78) 78
escherichia coli proteins - metabolism (76) 76
penicillin (71) 71
peptidoglycan - chemistry (70) 70
peptidyl transferases - metabolism (70) 70
crystal-structure (65) 65
models, molecular (64) 64
bacterial proteins - chemistry (63) 63
genetic aspects (63) 63
muramoylpentapeptide carboxypeptidase (62) 62
cell walls (61) 61
hexosyltransferases - metabolism (61) 61
staphylococcus-aureus (60) 60
peptidyl transferases - genetics (59) 59
humans (58) 58
carrier proteins (54) 54
identification (54) 54
carrier proteins - metabolism (51) 51
hexosyltransferases - genetics (51) 51
animals (50) 50
glycosyltransferases - genetics (50) 50
multienzyme complexes - metabolism (50) 50
penicillin-binding proteins - genetics (49) 49
cell wall - chemistry (48) 48
escherichia coli proteins - genetics (48) 48
peptidoglycan glycosyltransferase - genetics (48) 48
base sequence (46) 46
binding sites (46) 46
membrane proteins - metabolism (46) 46
peptidoglycan synthesis (46) 46
bacteriology (45) 45
multidisciplinary sciences (45) 45
genes, bacterial (44) 44
growth (44) 44
e coli (43) 43
substrate specificity (43) 43
genes (42) 42
gram-negative bacteria (42) 42
kinetics (42) 42
multienzyme complexes - genetics (42) 42
cell membrane - metabolism (41) 41
life sciences (41) 41
lipids (41) 41
peptidyl transferases (41) 41
cell biology (39) 39
gram-positive bacteria (39) 39
microbial sensitivity tests (39) 39
penicillin-binding protein (39) 39
cloning, molecular (38) 38
gene (38) 38
glycosylation (38) 38
peptidoglycan biosynthesis (38) 38
protein structure, tertiary (38) 38
resistance (38) 38
cell-wall (37) 37
streptococcus-pneumoniae (37) 37
biochemical phenomena, metabolism, and nutrition (36) 36
carrier proteins - genetics (36) 36
division (36) 36
escherichia coli - cytology (36) 36
glycosyltransferase (36) 36
hexosyltransferases (36) 36
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1. Full Text The penicillin‐binding proteins: structure and role in peptidoglycan biosynthesis
by Sauvage, Eric and Kerff, Frédéric and Terrak, Mohammed and Ayala, Juan A and Charlier, Paulette
FEMS Microbiology Reviews, ISSN 0168-6445, 03/2008, Volume 32, Issue 2, pp. 234 - 258
Penicillin‐binding proteins (PBPs) have been scrutinized for over 40 years. Recent structural information on PBPs together with the ongoing long‐term... 
3D structure | transpeptidase | penicillin‐binding | transglycosylase | peptidoglycan synthesis | Peptidoglycan synthesis | Transglycosylase | Penicillin-binding | Transpeptidase | BETA-LACTAM RESISTANCE | ACYL-ENZYME COMPLEX | ESCHERICHIA-COLI | penicillin-binding | ALA-PEPTIDASE REVEALS | MICROBIOLOGY | PREDICTED SECONDARY STRUCTURES | ENTEROCOCCUS-FAECIUM BM4339 | STREPTOCOCCUS-PNEUMONIAE | BACILLUS-SUBTILIS | ALANINE CARBOXYPEPTIDASE IA | CELL-WALL PEPTIDOGLYCAN | Protein Structure, Tertiary | Bacteria - metabolism | Peptidyl Transferases - metabolism | Bacteria - chemistry | Multienzyme Complexes - classification | Peptidoglycan Glycosyltransferase - metabolism | Peptidoglycan Glycosyltransferase - chemistry | Glycosyltransferases - chemistry | Penicillin-Binding Proteins - classification | Peptidyl Transferases - chemistry | Bacterial Proteins - chemistry | Multienzyme Complexes - metabolism | Penicillin-Binding Proteins - metabolism | Peptide Hydrolases - chemistry | Multienzyme Complexes - chemistry | Peptidoglycan - biosynthesis | Glycosyltransferases - metabolism | beta-Lactams - pharmacology | Penicillin-Binding Proteins - chemistry | Bacterial Proteins - metabolism | Bacterial Proteins - classification | beta-Lactamases - metabolism | Peptide Hydrolases - metabolism | Physiological aspects | Peptidoglycans
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2. Full Text SEDS proteins are a widespread family of bacterial cell wall polymerases
by Meeske, Alexander J and Riley, Eammon P and Robins, William P and Uehara, Tsuyoshi and Mekalanos, John J and Kahne, Daniel and Walker, Suzanne and Kruse, Andrew C and Bernhardt, Thomas G and Rudner, David Z
Nature, ISSN 0028-0836, 08/2016, Volume 537, Issue 7622, pp. 634 - 638
Elongation of rod-shaped bacteria is mediated by a dynamic peptidoglycan-synthetizing machinery called the Rod complex. Here we report that, in Bacillus... 
BETA-LACTAM RESISTANCE | GENE | BACILLUS-SUBTILIS | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | PENICILLIN-BINDING PROTEINS | DYNAMICS | FLIPPASE | PEPTIDOGLYCAN SYNTHESIS | PRECURSORS | DIVISION | Peptidoglycan Glycosyltransferase - metabolism | Bacillus subtilis - cytology | Peptidoglycan Glycosyltransferase - chemistry | Penicillin-Binding Proteins - classification | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Polymerization | Penicillin-Binding Proteins - genetics | Bacillus subtilis - enzymology | Cell Wall - chemistry | Penicillin-Binding Proteins - metabolism | Oligosaccharides - pharmacology | Peptidoglycan - biosynthesis | Peptidoglycan Glycosyltransferase - genetics | Phenotype | Bacillus subtilis - growth & development | Cell Division | Cell Wall - metabolism | Drug Design | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Drug Resistance, Bacterial - drug effects | Mutation | Bacillus subtilis - drug effects | Physiological aspects | Bacillus subtilis | Bacterial cell walls | Proteins | Antigens | Enzymes | Bacterial infections | Peptides | Penicillin | Bacteria | Lipids | Biosynthesis
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3. Full Text Peptidoglycan glycosyltransferase-ligand binding assay based on tryptophan fluorescence quenching
by Dahmane, Ismahene and Montagner, Caroline and Matagne, André and Dumbre, Shrinivas and Herdewijn, Piet and Terrak, Mohammed
Biochimie, ISSN 0300-9084, 09/2018, Volume 152, pp. 1 - 5
Peptidoglycan glycosyltransferases (GTase) of family 51 are essential enzymes for the synthesis of the glycan chains of the bacterial cell wall. They are... 
Peptidoglycan | Moenomycin | Lipid II | Glycosyltransferase | Fluorescence assay | CRYSTAL-STRUCTURE | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MONOFUNCTIONAL GLYCOSYLTRANSFERASE | STAPHYLOCOCCUS-AUREUS | PROTEINS | TRANSGLYCOSYLATION STEP | Uridine Diphosphate N-Acetylmuramic Acid - analogs & derivatives | Staphylococcus aureus - enzymology | Mutagenesis, Site-Directed | Peptidoglycan Glycosyltransferase - metabolism | Electrophoresis, Polyacrylamide Gel | Tryptophan - genetics | Enzyme Inhibitors - pharmacology | Spectrometry, Fluorescence | Substrate Specificity | Tryptophan - metabolism | Peptidoglycan Glycosyltransferase - genetics | Uridine Diphosphate N-Acetylmuramic Acid - metabolism | Bambermycins - metabolism | High-Throughput Screening Assays | Protein Binding | Ligands | Peptidoglycan Glycosyltransferase - antagonists & inhibitors | Circular Dichroism
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4. Full Text PBP1B glycosyltransferase and transpeptidase activities play different essential roles during the de novo regeneration of rod morphology in Escherichia coli
by Ranjit, Dev K and Jorgenson, Matthew A and Young, Kevin D
Journal of Bacteriology, ISSN 0021-9193, 2017, Volume 199, Issue 7
Peptidoglycan is a vital component of nearly all cell wall-bearing bacteria and is a valuable target for antibacterial therapy. However, despite decades of... 
PBP1A | Peptidoglycan | PBP1B | Spheroplast | Bacterial morphology | bacterial morphology | spheroplast | PEPTIDOGLYCAN SYNTHASE PBP1B | D-AMINO ACIDS | MICROBIOLOGY | CELL WALL POLYMERASES | L-FORMS | DIVISION | peptidoglycan | SHAPE | GRAM-NEGATIVE BACTERIA | Z-RING | PENICILLIN-BINDING PROTEINS | UNDECAPRENYL PHOSPHATE | Cell Proliferation | Escherichia coli - enzymology | Peptidoglycan Glycosyltransferase - metabolism | Escherichia coli Proteins - metabolism | Penicillin-Binding Proteins - genetics | Escherichia coli - cytology | Gene Expression Regulation, Enzymologic - physiology | Penicillin-Binding Proteins - metabolism | Serine-Type D-Ala-D-Ala Carboxypeptidase - genetics | Gene Expression Regulation, Bacterial - physiology | Peptidoglycan Glycosyltransferase - genetics | Escherichia coli Proteins - genetics | Mutation | Serine-Type D-Ala-D-Ala Carboxypeptidase - metabolism | Spheroplasts - physiology | Research | Escherichia coli | Glycosyltransferases | Peptidyl transferases
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5. Full Text Activities and regulation of peptidoglycan synthases
by Egan, Alexander J F and Biboy, Jacob and van 't Veer, Inge and Breukink, Eefjan and Vollmer, Waldemar
Philosophical transactions / Royal Society of London. Biological sciences, ISSN 0962-8436, 10/2015, Volume 370, Issue 1679, pp. 20150031 - 20150031
Peptidoglycan (PG) is an essential component in the cell wall of nearly all bacteria, forming a continuous, mesh-like structure, called the sacculus, around... 
Peptidoglycan | Penicillin-binding protein | Glycosyltransferase | Agricultural and Biological Sciences(all) | Lipid II | Carboxypeptidase | Biochemistry, Genetics and Molecular Biology(all) | Transpeptidase | transpeptidase | BACTERIAL CELL WALLS | ESCHERICHIA-COLI | penicillin-binding protein | DD-CARBOXYPEPTIDASE-TRANSPEPTIDASE | PEPTIDE CROSS-LINKING | IN-VITRO SYNTHESIS | KINETIC CHARACTERIZATION | carboxypeptidase | peptidoglycan | lipid II | glycosyltransferase | LIPID-II | BIOLOGY | STAPHYLOCOCCUS-AUREUS | NEWLY SYNTHESIZED PEPTIDOGLYCAN | Peptidoglycan Glycosyltransferase - metabolism | Peptidoglycan Glycosyltransferase - chemistry | Penicillin-Binding Proteins - classification | Peptidoglycan - chemistry | Models, Molecular | Substrate Specificity | Escherichia coli Proteins - metabolism | Penicillin-Binding Proteins - metabolism | Escherichia coli Proteins - classification | Peptidoglycan - biosynthesis | Penicillin-Binding Proteins - chemistry | Escherichia coli - metabolism | Kinetics | Escherichia coli Proteins - chemistry | 200 | 1001 | Review
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6. Full Text Isoprenoid Phosphonophosphates as Glycosyltransferase Acceptor Substrates
by Martinez Farias, Mario A and Kincaid, Virginia A and Annamalai, Venkatachalam R and Kiessling, Laura L
Journal of the American Chemical Society, ISSN 0002-7863, 06/2014, Volume 136, Issue 24, pp. 8492 - 8495
Glycosyltransferases that act on polyprenol pyrophosphate substrates are challenging to study because their lipid-linked substrates are difficult to isolate... 
MYCOBACTERIUM-TUBERCULOSIS | ARABINOGALACTAN | PEPTIDOGLYCAN | LENGTH CONTROL | MECHANISM | N-LINKED GLYCOSYLATION | BIOSYNTHESIS | CARBOHYDRATE POLYMERASE | INHIBITORS | CHEMISTRY, MULTIDISCIPLINARY | CHEMICAL SYNTHESIS | Glycosyltransferases - metabolism | Polyisoprenyl Phosphates - chemistry | Biocatalysis | Glycosyltransferases - chemistry | Substrate Specificity | Molecular Structure | Polyisoprenyl Phosphates - metabolism | Research | Catalysis | Analysis | Glycosyltransferases | Genes | Formations | Assembly | Communication
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7. Full Text The essential peptidoglycan glycosyltransferase MurG forms a complex with proteins involved in lateral envelope growth as well as with proteins involved in cell division in Escherichia coli
by Mohammadi, T and Karczmarek, A and Crouvoisier, M and Bouhss, A and Mengin-Lecreulx, D and den Blaauwen, T
Molecular Microbiology, ISSN 0950-382X, 2007, Volume 65, Issue 4, pp. 1106 - 1121
Summary In Escherichia coli many enzymes including MurG are directly involved in the synthesis and assembly of peptidoglycan. MurG is an essential... 
SHAPE | WALL | FTSZ | SPHERICAL CELLS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PENICILLIN-BINDING PROTEINS | MICROBIOLOGY | 1ST MEMBRANE STEP | Z RING | INHIBITORS | N-ACETYLGLUCOSAMINE TRANSFERASE | Cytoplasm - enzymology | Temperature | Escherichia coli - enzymology | Peptidoglycan Glycosyltransferase - metabolism | Fluorescence | Escherichia coli Proteins - metabolism | Immunoblotting | Cell Wall - enzymology | Escherichia coli - cytology | N-Acetylglucosaminyltransferases - metabolism | Protein Transport | Bacterial Outer Membrane Proteins - metabolism | Models, Biological | Cell Division | Protein Binding | Bacterial Proteins - metabolism | Transferases - metabolism | Escherichia coli
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8. Full Text Synthesis of Modified Peptidoglycan Precursor Analogues for the Inhibition of Glycosyltransferase
by Dumbre, Shrinivas and Derouaux, Adeline and Lescrinier, Eveline and Piette, André and Joris, Bernard and Terrak, Mohammed and Herdewijn, Piet
Journal of the American Chemical Society, ISSN 0002-7863, 06/2012, Volume 134, Issue 22, pp. 9343 - 9351
The peptidoglycan glycosyltransferases (GTs) are essential enzymes that catalyze the polymerization of glycan chains of the bacterial cell wall from lipid II... 
ACID | GLYCOSYL TRANSFERASE | CRYSTAL-STRUCTURE | ESCHERICHIA-COLI | LIPID-II | PENICILLIN-BINDING PROTEINS | MOENOMYCIN | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | CELL-WALL BIOSYNTHESIS | TRANSGLYCOSYLATION STEP | Peptidoglycan Glycosyltransferase - antagonists & inhibitors | Structure-Activity Relationship | Peptidoglycan Glycosyltransferase - metabolism | Peptidoglycan - pharmacology | Molecular Conformation | Peptidoglycan - chemistry | Analysis | Glycosyltransferases | Peptidoglycans | Chemical bonds | Polymerization | Glycosylation | Chemical properties
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9. Full Text Murgocil is a Highly Bioactive Staphylococcal-Specific Inhibitor of the Peptidoglycan Glycosyltransferase Enzyme MurG
by Mann, Paul A and Müller, Anna and Xiao, Li and Pereira, Pedro M and Yang, Christine and Ho Lee, Sang and Wang, Hao and Trzeciak, Joanna and Schneeweis, Jonathan and dos Santos, Margarida Moreira and Murgolo, Nicholas and She, Xinwei and Gill, Charles and Balibar, Carl J and Labroli, Marc and Su, Jing and Flattery, Amy and Sherborne, Brad and Maier, Richard and Tan, Christopher M and Black, Todd and Önder, Kamil and Kargman, Stacia and Monsma, Frederick J and Pinho, Mariana G and Schneider, Tanja and Roemer, Terry
ACS Chemical Biology, ISSN 1554-8929, 11/2013, Volume 8, Issue 11, pp. 2442 - 2451
Modern medicine is founded on the discovery of penicillin and subsequent small molecules that inhibit bacterial peptidoglycan (PG) and cell wall synthesis.... 
CELL-WALL SYNTHESIS | METHICILLIN RESISTANCE | TEICHOIC-ACID | BAD BUGS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | LIPID-II | BETA-LACTAM ANTIBIOTICS | ANTIBACTERIAL DISCOVERY | BACTERIAL PEPTIDOGLYCAN | Sterols - pharmacology | Staphylococcus aureus - enzymology | Peptidoglycan Glycosyltransferase - metabolism | Sterols - chemistry | Humans | Enzyme Inhibitors - pharmacology | Drug Resistance, Bacterial | Models, Molecular | Pyrazoles - chemistry | Computer Simulation | N-Acetylglucosaminyltransferases - antagonists & inhibitors | Anti-Bacterial Agents - pharmacology | Staphylococcus aureus - drug effects | Bacterial Outer Membrane Proteins - antagonists & inhibitors | Microscopy, Fluorescence | Pyrazoles - pharmacology
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10. Full Text Structural Insight into the Transglycosylation Step of Bacterial Cell-Wall Biosynthesis
by Andrew L. Lovering and Liza H. de Castro and Daniel Lim and Natalie C. J. Strynadka
Science, ISSN 0036-8075, 3/2007, Volume 315, Issue 5817, pp. 1402 - 1405
Peptidoglycan glycosyltransferases (GTs) catalyze the polymerization step of cell-wall biosynthesis, are membrane-bound, and are highly conserved across all... 
Enzymes | Jaw | Antibacterials | Antibiotics | Polymerization | Lipids | Reports | Biochemistry | Diphosphates | Regional identity | Sugars | GLYCOSYLTRANSFERASE MODULE | BACTERIOPHAGE-LAMBDA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | VANCOMYCIN RESISTANCE | PBP1B | STAPHYLOCOCCUS-AUREUS | PROTEINS | KINETIC CHARACTERIZATION | Staphylococcus aureus - enzymology | Molecular Sequence Data | Multienzyme Complexes - metabolism | Crystallography, X-Ray | Oligosaccharides - pharmacology | Penicillin-Binding Proteins - chemistry | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Oligosaccharides - chemistry | Binding Sites | Staphylococcus aureus - metabolism | Carbohydrate Sequence | Protein Structure, Tertiary | Amino Acid Sequence | Aminoacyltransferases - chemistry | Catalytic Domain | Peptidoglycan Glycosyltransferase - metabolism | Enzyme Inhibitors - metabolism | Peptidoglycan Glycosyltransferase - chemistry | Enzyme Inhibitors - pharmacology | Models, Molecular | Anti-Bacterial Agents - metabolism | Glycosylation | Oligosaccharides - metabolism | Penicillin-Binding Proteins - metabolism | Protein Folding | Amino Acid Motifs | Multienzyme Complexes - chemistry | Peptidoglycan - biosynthesis | Cell Wall - metabolism | Apoenzymes - chemistry | Aminoacyltransferases - metabolism | Protein Conformation | Carbohydrate Conformation | Bacterial cell walls | Biosynthesis | Synthesis | Research
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11. Full Text Positive cooperativity between acceptor and donor sites of the peptidoglycan glycosyltransferase
by Bury, Daniel and Dahmane, Ismahene and Derouaux, Adeline and Dumbre, Shrinivas and Herdewijn, Piet and Matagne, Andre´ and Breukink, Eefjan and Mueller-Seitz, Erika and Petz, Michael and Terrak, Mohammed
Biochemical Pharmacology, ISSN 0006-2952, 01/2015, Volume 93, Issue 2, pp. 141 - 150
The glycosyltransferases of family 51 (GT51) catalyze the polymerization of lipid II to form linear glycan chains, which, after cross linking by the... 
Moenomycin | Peptidoglycan | Lipid II | SPR | Glycosyltransferase | CRYSTAL-STRUCTURE | ESCHERICHIA-COLI | MONOFUNCTIONAL GLYCOSYLTRANSFERASE | KINETIC CHARACTERIZATION | BINDING PROTEIN 1B | GLYCOSYL TRANSFERASE | LIPID-II | PHARMACOLOGY & PHARMACY | STAPHYLOCOCCUS-AUREUS | TRANSGLYCOSYLATION STEP | Protein Structure, Tertiary | Microbial Interactions - physiology | Bambermycins - metabolism | Peptidoglycan Glycosyltransferase - metabolism | Peptidoglycan Glycosyltransferase - chemistry | Protein Structure, Secondary | Surface Plasmon Resonance - methods | Protein Binding - physiology | Staphylococcus aureus - metabolism
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12. Full Text Cooperativity of peptidoglycan synthases active in bacterial cell elongation
by Banzhaf, M and van den Berg van Saparoea, B and Terrak, M and Fraipont, C and Egan, A and Philippe, J and Zapun, A and Breukink, E and Nguyen-Distèche, M and den Blaauwen, T and Vollmer, W
Molecular Microbiology, ISSN 0950-382X, 2012, Volume 85, Issue 1, pp. 179 - 194
Growth of the bacterial cell wall peptidoglycan sacculus requires the co-ordinated activities of peptidoglycan synthases, hydrolases and cell morphogenesis... 
WALL | PENICILLIN-BINDING-PROTEINS | BACILLUS-SUBTILIS | MREB | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | MUREIN | PBP1B | MICROBIOLOGY | GLYCOSYLTRANSFERASE ACTIVITY | MEMBRANE-PROTEINS | DIVISION | Peptidoglycan - biosynthesis | Escherichia coli - enzymology | Peptidoglycan Glycosyltransferase - metabolism | Cell Wall - metabolism | Escherichia coli Proteins - metabolism | Escherichia coli - growth & development | Penicillin-Binding Proteins - metabolism
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13. Full Text In vitro Reconstitution of Peptidoglycan Assembly from the Gram-Positive Pathogen Streptococcus pneumoniae
by Zapun, André and Philippe, Jules and Abrahams, Katherine A and Signor, Luca and Roper, David I and Breukink, Eefjan and Vernet, Thierry
ACS Chemical Biology, ISSN 1554-8929, 12/2013, Volume 8, Issue 12, pp. 2688 - 2696
Understanding the molecular basis of bacterial cell wall assembly is of paramount importance in addressing the threat of increasing antibiotic resistance... 
D-AMINO ACIDS | BACTERIAL CELL-WALLS | BACILLUS-MEGATERIUM | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | LIPID-II | PENICILLIN-BINDING PROTEINS | GENE DISRUPTION | SYNTHESIZED PEPTIDOGLYCAN | GLYCOSYLTRANSFERASES | Peptidyl Transferases - genetics | Peptidoglycan - chemistry | Uridine Diphosphate N-Acetylmuramic Acid - chemistry | Glutamine - metabolism | Homologous Recombination | Penicillin-Binding Proteins - genetics | Cell Wall - enzymology | Uridine Diphosphate N-Acetylmuramic Acid - metabolism | Cell Wall - drug effects | Penicillin-Binding Proteins - chemistry | Streptococcus pneumoniae - chemistry | Streptococcus pneumoniae - genetics | Uridine Diphosphate N-Acetylmuramic Acid - analogs & derivatives | Peptidyl Transferases - metabolism | Streptococcus pneumoniae - drug effects | Peptidoglycan Glycosyltransferase - metabolism | Peptidoglycan Glycosyltransferase - chemistry | Peptidyl Transferases - chemistry | Cell Wall - genetics | Peptidoglycan - genetics | Cell Wall - chemistry | Penicillin-Binding Proteins - metabolism | Peptidoglycan - biosynthesis | Peptidoglycan Glycosyltransferase - genetics | beta-Lactams - pharmacology | Genetic Engineering | Anti-Bacterial Agents - pharmacology | Glutamic Acid - metabolism | beta-Lactam Resistance - genetics | Streptococcus pneumoniae - enzymology | beta-Lactam Resistance - drug effects | beta-Lactam Resistance | Peptidyl Transferases | Biochemistry, Molecular Biology | Peptidoglycan Glycosyltransferase | beta-Lactams | Streptococcus pneumoniae | Cell Wall | Glutamic Acid | Life Sciences | Penicillin-Binding Proteins | Peptidoglycan | Anti-Bacterial Agents | Uridine Diphosphate N-Acetylmuramic Acid | Biomolecules | Glutamine
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14. Full Text Targeting Bacterial Cell Wall Peptidoglycan Synthesis by Inhibition of Glycosyltransferase Activity
by Mesleh, Michael F and Rajaratnam, Premraj and Conrad, Mary and Chandrasekaran, Vasu and Liu, Christopher M and Pandya, Bhaumik A and Hwang, You Seok and Rye, Peter T and Muldoon, Craig and Becker, Bernd and Zuegg, Johannes and Meutermans, Wim and Moy, Terence I
Chemical Biology & Drug Design, ISSN 1747-0277, 02/2016, Volume 87, Issue 2, pp. 190 - 199
Synthesis of bacterial cell wall peptidoglycan requires glycosyltransferase enzymes that transfer the disaccharide–peptide from lipid II onto the growing... 
drug discovery | NMR spectroscopy | glycosyltransferase | penicillin‐binding protein | transglycosylase | penicillin-binding protein | CHEMISTRY, MEDICINAL | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | MONOFUNCTIONAL GLYCOSYLTRANSFERASE | KINETIC CHARACTERIZATION | ANTIBACTERIAL ACTIVITY | BIOSYNTHESIS | MOENOMYCIN | STAPHYLOCOCCUS-AUREUS | BINDING | Vancomycin - metabolism | Oligosaccharides - pharmacology | Vancomycin - chemistry | Anti-Bacterial Agents - chemistry | Oligosaccharides - chemistry | Vancomycin - pharmacology | Drug Design | Inhibitory Concentration 50 | Peptidoglycan Glycosyltransferase - antagonists & inhibitors | Penicillin-Binding Proteins - antagonists & inhibitors | Binding Sites | Protein Structure, Tertiary | Bacterial Proteins - antagonists & inhibitors | Escherichia coli - enzymology | Peptidoglycan Glycosyltransferase - metabolism | Magnetic Resonance Spectroscopy | Anti-Bacterial Agents - metabolism | Oligosaccharides - metabolism | Penicillin-Binding Proteins - metabolism | Peptidoglycan - biosynthesis | Cell Wall - metabolism | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Molecular Docking Simulation | Staphylococcus aureus - drug effects | Protein binding
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15. Full Text Lipoprotein Cofactors Located in the Outer Membrane Activate Bacterial Cell Wall Polymerases
by Paradis-Bleau, Catherine and Markovski, Monica and Uehara, Tsuyoshi and Lupoli, Tania J and Walker, Suzanne and Kahne, Daniel E and Bernhardt, Thomas G
Cell, ISSN 0092-8674, 12/2010, Volume 143, Issue 7, pp. 1110 - 1120
Most bacteria surround themselves with a peptidoglycan (PG) exoskeleton synthesized by polysaccharide polymerases called penicillin-binding proteins (PBPs).... 
MORPHOGENESIS | MUTANTS | PEPTIDOGLYCAN BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | COMPLEXES | PENICILLIN-BINDING PROTEINS | PBP1B | HAEMOPHILUS-INFLUENZAE | IDENTIFICATION | DIMERS | CELL BIOLOGY | Peptidoglycan - metabolism | Escherichia coli - enzymology | Peptidoglycan Glycosyltransferase - metabolism | Escherichia coli Proteins - metabolism | Cell Wall - enzymology | Escherichia coli - cytology | Penicillin-Binding Proteins - metabolism | Peptidoglycan - biosynthesis | Bacterial Outer Membrane Proteins - metabolism | Cell Wall - metabolism | Escherichia coli - metabolism | Lipoproteins - metabolism | Serine-Type D-Ala-D-Ala Carboxypeptidase - metabolism | Polymerization | Enzymes | Polysaccharides | Biosynthesis | Blood lipids | Penicillin | Lipoproteins | Exoskeleton | Antibiotics | Cell walls | Outer membranes | penicillin-binding protein | peptidoglycans | Cofactors
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