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1. Full Text Metal‐Mediated Cross‐Linking in the Generation of a Marine‐Mussel Adhesive
by Sever, Mary J and Weisser, Jaime T and Monahan, Jennifer and Srinivasan, Shalini and Wilker, Jonathan J
Angewandte Chemie International Edition, ISSN 1433-7851, 01/2004, Volume 43, Issue 4, pp. 448 - 450
Iron muscles into mussels: Marine mussels adhere to rocks with a protein‐based glue. An iron complex is the key curing agent in this adhesive, and the iron... 
peptidomimetics | functional materials | proteins | bioinorganic chemistry | transition metals | Proteins | Transition metals | Bioinorganic chemistry | Peptidomimetics | Functional materials | IRON(III) | COORDINATION CHEMISTRY | COMPLEXES | IRON TRANSPORT COMPOUNDS | CHEMISTRY, MULTIDISCIPLINARY | CATECHOL DIOXYGENASES | TRANSFORM INFRARED-SPECTROSCOPY | MODELS | ENTEROBACTIN | BYSSUS | Metals - analysis | Ferric Compounds - chemistry | Proteins - isolation & purification | Oxygen - metabolism | Adhesives - chemistry | Iron - analysis | Nitrates - chemistry | Metals - chemistry | Dihydroxyphenylalanine - analysis | Oxygen - chemistry | Adhesives - metabolism | Bivalvia - chemistry | Cross-Linking Reagents - chemistry | Adhesives - isolation & purification | Electron Spin Resonance Spectroscopy | Oxidation-Reduction | Peptides - chemistry | Iron - chemistry | Bivalvia - physiology | Models, Molecular | Iron - metabolism | Cross-Linking Reagents - metabolism | Dihydroxyphenylalanine - chemistry | Dihydroxyphenylalanine - metabolism | Metals - metabolism | Animals | Proteins - metabolism | Protein Binding | Ligands | Proteins - chemistry | Spectrophotometry
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2. Full Text Unusual Amino Acids in Medicinal Chemistry
by Blaskovich, Mark A. T
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2016, Volume 59, Issue 24, pp. 10807 - 10836
Unusual amino acids are fundamental building blocks of modern medicinal chemistry. The combination of readily functionalized amine and carboxyl groups attached... 
POTENT INHIBITOR | CHEMISTRY, MEDICINAL | HEPATITIS-C VIRUS | THYROTROPIN-RELEASING-HORMONE | MATRIX-METALLOPROTEINASE INHIBITORS | PHARMACOLOGICAL CHARACTERIZATION | BIOLOGICAL-ACTIVITY | METABOTROPIC GLUTAMATE RECEPTORS | SERINE-PROTEASE | ANGIOTENSIN-II ANALOGS | NS3/4A PROTEASE INHIBITOR | Peptidomimetics - pharmacology | Humans | Amino Acids - chemistry | Peptidomimetics - chemistry | Drug Discovery | Amino Acids - pharmacology | Chemistry, Pharmaceutical
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3. Full Text 2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products
by Borthwick, Alan D
Chemical Reviews, ISSN 0009-2665, 07/2012, Volume 112, Issue 7, pp. 3641 - 3716
MAMMALIAN-CELL CYCLE | CONCISE TOTAL-SYNTHESIS | SOLID-PHASE SYNTHESIS | HOST-SPECIFIC PHYTOTOXIN | MARINE-DERIVED FUNGUS | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | BIOAVAILABLE OXYTOCIN ANTAGONISTS | PRENYLATED INDOLE ALKALOIDS | ENANTIOSELECTIVE TOTAL-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | CANCER RESISTANCE PROTEIN | Peptidomimetics - pharmacology | Chemistry, Pharmaceutical - methods | Peptidomimetics - chemical synthesis | Diketopiperazines - chemistry | Humans | Biological Products - pharmacology | Peptidomimetics - chemistry | Diketopiperazines - pharmacology | Chemistry Techniques, Synthetic - methods | Biological Products - chemical synthesis | Biological Products - chemistry | Animals | Cell Line, Tumor | Catalysis | Diketopiperazines - chemical synthesis | Piperazine | Analysis | Chemical bonds | Amino acids | Chemical properties | Ring formation (Chemistry) | Diels-Alder reaction | Acylation | Enolates
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4. Full Text Fragment-Based Discovery of Bromodomain Inhibitors Part 1: Inhibitor Binding Modes and Implications for Lead Discovery
by Chung, Chun-wa and Dean, Anthony W and Woolven, James M and Bamborough, Paul
Journal of Medicinal Chemistry, ISSN 0022-2623, 01/2012, Volume 55, Issue 2, pp. 576 - 586
Bromodomain-containing proteins are key epigenetic regulators of gene transcription and readers of the histone code. However, the therapeutic benefits of... 
CHEMISTRY, MEDICINAL | HUMAN BRD2 BROMODOMAIN | LIGANDS | DRUG DISCOVERY | PARACETAMOL | HISTONE H4 RECOGNITION | CHROMATIN MODIFICATIONS | LEUKEMIA | LESSONS | PROTEINS | ASSOCIATION | Protein Structure, Tertiary | Amino Acid Sequence | Transcription Factors - chemistry | Pyridines - chemistry | Acetaminophen - chemistry | Humans | RNA-Binding Proteins - chemistry | Models, Molecular | Molecular Sequence Data | Crystallography, X-Ray | Transcription Factors - antagonists & inhibitors | Peptidomimetics - chemistry | Nuclear Proteins - chemistry | Pyrrolidinones - chemistry | Indolizines - chemistry | Nuclear Proteins - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Protein Binding | Molecular Structure | Protein-Serine-Threonine Kinases - chemistry | Quinazolinones - chemistry | Fluorescence Polarization | Quantitative Structure-Activity Relationship | RNA-Binding Proteins - antagonists & inhibitors
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5. Full Text Routes to Hydrogen Bonding Chain‐End Functionalized Polymers
by Bertrand, Arthur and Lortie, Frédéric and Bernard, Julien
Macromolecular Rapid Communications, ISSN 1022-1336, 12/2012, Volume 33, Issue 24, pp. 2062 - 2091
The contribution of supramolecular chemistry to polymer science opens new perspectives for the design of polymer materials exhibiting valuable properties and... 
telechelics | hydrogen bonding | stimuli‐sensitive polymers | supramolecular chemistry | macromolecular engineering | stimuli-sensitive polymers | POLYMER SCIENCE | GRAFT-COPOLYMERS | CLICK CHEMISTRY | REVERSIBLE POLYMER | ACID-TERMINATED POLYDIMETHYLSILOXANES | PHASE-SEPARATION | SUPRAMOLECULAR BLOCK-COPOLYMERS | MOLECULAR RECOGNITION | THERMOPLASTIC ELASTOMERS | STAR POLYMERS | ASSOCIATION | Polymers - chemical synthesis | Polymerization | Peptidomimetics - chemistry | Urethane - chemistry | Pyrimidinones - chemistry | Urea - chemistry | Hydrogen Bonding | Carboxylic Acids - chemistry | Benzoic Acid - chemistry | Polymers - chemistry | Triazines - chemistry | Oligopeptides - chemistry | Benzamides - chemistry | Polymer industry | Polymers | Hydrogen | Hydrogen bonding
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6. Full Text Methyl propiolate and 3-butynone: Starting points for synthesis of amphiphilic 1,2,3-triazole peptidomimetics for antimicrobial evaluation
by Bakka, Thomas A and Strøm, Morten B and Andersen, Jeanette H and Gautun, Odd R
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 10/2017, Volume 25, Issue 20, pp. 5380 - 5395
A library of 29 small 1,4-substituted 1,2,3-triazoles was prepared for studies of antimicrobial activity. The pharmacophore model investigated with these... 
1,2,3-Triazoles | Antibacterial | Click chemistry | Marine natural product mimics | ANTIBIOTICS | CHEMISTRY, MEDICINAL | AZIDES | MIMICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | CATALYST | DISCOVERY | HYDROCHLORIDE | PEPTIDES | AMINES | ESTERS | PHARMACOPHORE | Propionates - chemistry | Enterococcus faecalis - drug effects | Triazoles - chemistry | Escherichia coli - drug effects | Staphylococcus - drug effects | Alkynes - chemistry | Structure-Activity Relationship | Pseudomonas aeruginosa - drug effects | Surface-Active Agents - pharmacology | Anti-Bacterial Agents - chemical synthesis | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Triazoles - pharmacology | Peptidomimetics | Anti-Bacterial Agents - chemistry | Butyrates - chemistry | Triazoles - chemical synthesis | Anti-Bacterial Agents - pharmacology | Molecular Structure | Surface-Active Agents - chemistry | Surface-Active Agents - chemical synthesis | Triazoles | Chemical oceanography | Anti-infective agents | Ketones | Analysis | Escherichia coli | Organic chemistry: 441 | VDP | Organisk kjemi: 441 | Chemistry: 440 | Matematikk og Naturvitenskap: 400 | Mathematics and natural science: 400 | Kjemi: 440
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7. Full Text Sulfur, selenium and tellurium pseudopeptides: Synthesis and biological evaluation
by Shaaban, Saad and Sasse, Florenz and Burkholz, Torsten and Jacob, Claus
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2014, Volume 22, Issue 14, pp. 3610 - 3619
A new series of sulfur, selenium and tellurium peptidomimetic compounds was prepared employing the Passerini and Ugi isocyanide based multicomponent reactions... 
Isonitrile based multicomponent reactions (IMCR) | Redox-modulation | Lipinski’s Rule of Five | Antimicrobial activity | Tellurium | Anticancer activity | Lipinski's Rule of Five | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | LIBRARIES | MULTICOMPONENT REACTIONS | CHEMISTRY | WATER | Peptidomimetics - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Bacteria - drug effects | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Bacteria - growth & development | MCF-7 Cells | Anti-Bacterial Agents - chemistry | Antineoplastic Agents - pharmacology | Molecular Structure | Fungi - growth & development | Sulfur - chemistry | Antifungal Agents - pharmacology | Selenium - chemistry | Peptidomimetics - pharmacology | Fungi - drug effects | Peptides - chemistry | Peptidomimetics - chemistry | Tellurium - chemistry | Antineoplastic Agents - chemistry | Anti-Bacterial Agents - chemical synthesis | Cell Line, Tumor | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Cell Cycle - drug effects | Drug Screening Assays, Antitumor | Sulfur compounds | Selenium | Index Medicus
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8. Full Text 1,2,3-Triazole Stabilized Neurotensin-Based Radiopeptidomimetics for Improved Tumor Targeting
by Mascarin, Alba and Valverde, Ibai E and Vomstein, Sandra and Mindt, Thomas L
Bioconjugate Chemistry, ISSN 1043-1802, 10/2015, Volume 26, Issue 10, pp. 2143 - 2152
Neurotensin (NT) is a regulatory peptide with nanomolar affinity toward NT receptors, which are overexpressed by different clinically relevant tumors. Its... 
CATABOLISM | SOLID-PHASE SYNTHESIS | ANALOGS | CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | RECEPTOR | BIODISTRIBUTION | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDE | IN-VITRO | PEPTIDOMIMETICS | RADIOPHARMACEUTICALS | Chemistry Techniques, Synthetic | Receptors, Neurotensin - metabolism | Triazoles - chemistry | Humans | Half-Life | Peptidomimetics - chemistry | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Cycloaddition Reaction | HT29 Cells | Tissue Distribution | Xenograft Model Antitumor Assays | Isotope Labeling - methods | Neurotensin - chemistry | Peptide Fragments - chemistry | Animals | Mice, Nude | Peptidomimetics - pharmacokinetics | Female | Antineoplastic Agents - pharmacokinetics | Lutetium - chemistry | Molecular Targeted Therapy - methods | Radioisotopes - chemistry
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9. Full Text Helix-mediated protein–protein interactions as targets for intervention using foldamers
by Edwards, Thomas A and Wilson, Andrew J
Amino Acids, ISSN 0939-4451, 8/2011, Volume 41, Issue 3, pp. 743 - 754
Protein–protein interactions (PPIs) play a central role in virtually all biological processes and have been the focus of intense investigation from structural... 
Life Sciences | Biochemistry, general | Chemical biology | Foldamers | Analytical Chemistry | Protein–protein interactions | Life Sciences, general | Neurobiology | Proteomics | Biochemical Engineering | Helix mimetics | Protein-protein interactions | HYDROGEN-BOND-SURROGATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIV-1 CAPSID PROTEIN | STRUCTURAL-CHARACTERIZATION | BH3 DOMAINS | DIMERIZATION DOMAIN | BETA-PEPTIDES | ESTROGEN-RECEPTOR | INHIBITION | IN-VIVO | ALPHA/BETA-PEPTIDE FOLDAMERS | Receptors, Notch - metabolism | Amino Acids - chemistry | HIV Envelope Protein gp41 - metabolism | Proto-Oncogene Proteins - chemistry | HIV Envelope Protein gp41 - chemistry | Proto-Oncogene Proteins c-mdm2 - chemistry | Proto-Oncogene Proteins c-bcl-2 - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Receptors, Cytoplasmic and Nuclear - chemistry | Hypoxia-Inducible Factor 1, alpha Subunit - chemistry | Proto-Oncogene Proteins c-bcl-2 - chemistry | Capsid - metabolism | Proto-Oncogene Proteins c-mdm2 - metabolism | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Repressor Proteins - chemistry | Peptides - chemistry | Protein Interaction Domains and Motifs - drug effects | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | Nuclear Proteins - chemistry | Peptides - pharmacology | Protein Interaction Mapping | Receptors, Notch - chemistry | Peptidomimetics | Tumor Suppressor Protein p53 - chemistry | Receptors, Cytoplasmic and Nuclear - metabolism | Enzymes | Amino acids | Locks | Mathematical models | Biology | Biological | Inhibition | Molecular biology
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10. Full Text Guanylated Diamines, Triamines, and Polyamines: Chemistry and Biological Properties
by Castagnolo, Daniele and Schenone, Silvia and Botta, Maurizio
Chemical Reviews, ISSN 0009-2665, 09/2011, Volume 111, Issue 9, pp. 5247 - 5300
VERBESINA-CARACASANA | LATHYRUS-SATIVUS SEEDLINGS | CLONIDINE-DISPLACING SUBSTANCE | CHLORHEXIDINE DIGLUCONATE IMPURITIES | POTENT ANTIMALARIAL ACTIVITY | SOLID-PHASE SYNTHESIS | NITRIC-OXIDE SYNTHASE | AMIDE BOND PEPTIDOMIMETICS | ALBIZZIA-JULIBRISSIN DURAZZ | HIGHLY SELECTIVE INHIBITORS | CHEMISTRY, MULTIDISCIPLINARY | Antifungal Agents - pharmacology | Antihypertensive Agents - pharmacology | Histone Demethylases - antagonists & inhibitors | Polyamines - chemistry | Humans | Enzyme Inhibitors - pharmacology | Nitric Oxide Synthase - antagonists & inhibitors | Guanidines - pharmacology | Antifungal Agents - chemistry | Antiprotozoal Agents - chemistry | Hypoglycemic Agents - chemistry | Agmatine - pharmacology | Antiprotozoal Agents - pharmacology | Hypoglycemic Agents - pharmacology | Guanidines - chemistry | Antihypertensive Agents - chemistry | Polyamines - pharmacology | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Agmatine - chemistry | Diamines - chemistry | Anti-Bacterial Agents - pharmacology | Psychological aspects | Biological research | Alkaloids | Structure | Polyamines | Biology, Experimental
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11. Full Text Synthesis of a Biologically Active Triazole‐Containing Analogue of Cystatin A Through Successive Peptidomimetic Alkyne–Azide Ligations
by Valverde, Ibai E and Lecaille, Fabien and Lalmanach, Gilles and Aucagne, Vincent and Delmas, Agnès F
Angewandte Chemie International Edition, ISSN 1433-7851, 01/2012, Volume 51, Issue 3, pp. 718 - 722
“Click” protein: CuI‐catalyzed cycloaddition of azides and terminal alkynes has been applied to the successive ligations of three unprotected peptide... 
click chemistry | peptidomimetics | proteins | synthetic methods | proteases | SOLID-PHASE SYNTHESIS | TERMINAL ALKYNES | CYSTEINE CATHEPSINS | CHEMISTRY, MULTIDISCIPLINARY | CLICK-CLICK | STEFIN-A | CHEMICAL-SYNTHESIS | INHIBITORS | PEPTIDE-SYNTHESIS | CYCLIC TETRAPEPTIDES | Amino Acid Sequence | Cystatin A - chemical synthesis | Triazoles - chemistry | Humans | Neoplasm Invasiveness - prevention & control | Cystatin A - chemistry | Click Chemistry - methods | Molecular Sequence Data | Alkynes - chemistry | Peptidomimetics - chemistry | Azides - chemistry | Cyclization | Cystatin A - pharmacology | Cell Line, Tumor | Triazoles - chemical synthesis | Cathepsins - antagonists & inhibitors | Neoplasm Invasiveness | Click Chemistry | Biochemistry, Molecular Biology | Cathepsins | Life Sciences | Azides | Peptidomimetics | Triazoles | Cystatin A | Alkynes
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12. Full Text Ligand Binding Stepwise Disrupts Water Network in Thrombin: Enthalpic and Entropic Changes Reveal Classical Hydrophobic Effect
by Biela, Adam and Sielaff, Frank and Terwesten, Felix and Heine, Andreas and Steinmetzer, Torsten and Klebe, Gerhard
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2012, Volume 55, Issue 13, pp. 6094 - 6110
Well-ordered water molecules are displaced from thrombin’s hydrophobic S3/4-pocket by P3-varied ligands (Gly, d-Ala, d-Val, d-Leu to d-Cha with increased... 
BOVINE THROMBIN | DOT-PI INTERACTIONS | HUMAN ALPHA-THROMBIN | CHEMISTRY, MEDICINAL | S1 POCKET | AFFINITY | THERMODYNAMIC ANALYSIS | CRYSTAL-STRUCTURE | AM1-BCC MODEL | EFFICIENT GENERATION | INHIBITORS | Benzylamines - chemical synthesis | Stereoisomerism | Humans | Molecular Conformation | Thrombin - antagonists & inhibitors | Amino Acids - chemistry | Crystallography, X-Ray | Fibrinogen - chemistry | Proline - chemical synthesis | Benzyl Compounds - chemistry | Thermodynamics | Drug Design | Water - chemistry | Binding Sites | Amidines - chemical synthesis | Proline - analogs & derivatives | Sulfonamides - chemistry | Peptidomimetics - chemistry | Amidines - chemistry | Molecular Dynamics Simulation | Proline - chemistry | Sulfonamides - chemical synthesis | Benzylamines - chemistry | Hydrogen Bonding | Thrombin - chemistry | Hydrophobic and Hydrophilic Interactions | Protein Binding | Calorimetry | Ligands
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13. Recent advances in non-peptidomimetic dipeptidyl peptidase 4 inhibitors: Medicinal chemistry and preclinical aspects
by Liu, Y and Hu, Y and Liu, T
Current Medicinal Chemistry, ISSN 0929-8673, 08/2012, Volume 19, Issue 23, pp. 3982 - 3999
Dipeptidyl peptidase 4 (DPP-4), a substrate-specific serine protease, has been validated as a promising drug target for the treatment of type 2 diabetes. DPP-4... 
Analogs | Type 2 diabetes | Medicinal chemistry | Non-peptidomimetic | Inhibitors | SAR | DPP-4 | Drug design | Selectivity | Preclinical | selectivity | inhibitors | CHEMISTRY, MEDICINAL | drug design | BIOCHEMISTRY & MOLECULAR BIOLOGY | DPP-IV INHIBITOR | DISCOVERY | DIABETES-MELLITUS | IN-VITRO | type 2 diabetes | JANUVIA(TM) SITAGLIPTIN | preclinical | non-peptidomimetic | BIOLOGICAL EVALUATION | PHARMACOLOGY & PHARMACY | OPTIMIZATION | HIGHLY POTENT | DERIVATIVES | medicinal chemistry | RATIONAL DESIGN | Amines - chemistry | Hypoglycemic Agents - therapeutic use | Quinolizines - therapeutic use | Dipeptidyl Peptidase 4 - metabolism | Dipeptidyl Peptidase 4 - chemistry | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Organophosphorus Compounds - therapeutic use | Dipeptidyl-Peptidase IV Inhibitors - chemistry | Organophosphorus Compounds - chemistry | Hypoglycemic Agents - chemistry | Piperidones - therapeutic use | Xanthines - therapeutic use | Chemistry, Pharmaceutical | Piperidones - chemistry | Xanthines - chemistry | Peptidomimetics | Amines - therapeutic use | Diabetes Mellitus, Type 2 - drug therapy | Drug Evaluation, Preclinical | Quinolizines - chemistry
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14. Full Text Ruthenium-Catalyzed Synthesis of 5‑Amino-1,2,3-triazole-4-carboxylates for Triazole-Based Scaffolds: Beyond the Dimroth Rearrangement
by Ferrini, Serena and Chandanshive, Jay Zumbar and Lena, Stefano and Comes Franchini, Mauro and Giannini, Giuseppe and Tafi, Andrea and Taddei, Maurizio
The Journal of Organic Chemistry, ISSN 0022-3263, 03/2015, Volume 80, Issue 5, pp. 2562 - 2572
The 5-amino-1,2,3-triazole-4-carboxylic acid is a suitable molecule for the preparation of collections of peptidomimetics or biologically active compounds... 
CYCLOADDITION | YNAMIDES | PEPTIDOMIMETICS | AZIDES | SCOPE | 1,2,3-TRIAZOLES | AMIDE | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | INHIBITORS | Triazoles - chemistry | Amino Acids - chemistry | HSP90 Heat-Shock Proteins - agonists | Peptidomimetics - chemistry | Dipeptides - chemistry | Azides - chemistry | Cycloaddition Reaction | Ruthenium - chemistry | Triazoles - pharmacology | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Carboxylic Acids - chemistry | HSP90 Heat-Shock Proteins - chemistry | Inhibitory Concentration 50 | Triazoles - chemical synthesis | Catalysis | Research | Ring formation (Chemistry) | Chemical properties | Chemical synthesis | Triazoles | Rhenium catalysts
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15. Full Text Isoxazolidine: A Privileged Scaffold for Organic and Medicinal Chemistry
by Berthet, Mathéo and Cheviet, Thomas and Dujardin, Gilles and Parrot, Isabelle and Martinez, Jean
Chemical Reviews, ISSN 0009-2665, 12/2016, Volume 116, Issue 24, pp. 15235 - 15283
The isoxazolidine ring represents one of the privileged structures in medicinal chemistry, and there have been an increasing number of studies on isoxazolidine... 
DOUBLE-BOND POSITION | CARBOHYDRATE-DERIVED NITRONE | POLYCYCLIC AROMATIC-HYDROCARBONS | INTRAMOLECULAR BROMO-AMINATION | DNA-INTERCALATING AGENTS | 1,3-DIPOLAR CYCLOADDITION REACTIONS | N-DEMETHYLATIVE REARRANGEMENT | ACID-CATALYZED REARRANGEMENT | ENANTIOSELECTIVE NITRONE CYCLOADDITIONS | HIGHLY STEREOSELECTIVE-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | Nucleosides - chemical synthesis | Oxidation-Reduction | Peptidomimetics - chemical synthesis | Antineoplastic Agents - chemical synthesis | Carbohydrates - chemical synthesis | Isoxazoles - chemistry | Benzazepines - chemical synthesis | Cycloaddition Reaction | Anti-Infective Agents - chemical synthesis | Isoxazoles - chemical synthesis | Pyridones - chemical synthesis | Cyclization | beta-Lactams - chemical synthesis | Peptide Nucleic Acids - chemical synthesis | Oxazines - chemical synthesis | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis
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16. Full Text Mid-size Drugs Based on Peptides and Peptidomimetics
: A New Drug Category
by Tamamura, Hirokazu and Kobayakawa, Takuya and Ohashi, Nami
01/2018, 1st ed. 2018, SpringerBriefs in Pharmaceutical Science & Drug Development, ISBN 9789811076909, 113
This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents.... 
Chemistry | Pharmaceutical technology | Chemistry, Organic | Medicinal Chemistry | Pharmaceutical Sciences/Technology | Organic Chemistry
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17. Full Text Synthesis of Fluorinated Cyclopropyl Amino Acid Analogues: Toward the Synthesis of Original Fluorinated Peptidomimetics
by Milanole, Gaëlle and Couve-Bonnaire, Samuel and Bonfanti, Jean-François and Jubault, Philippe and Pannecoucke, Xavier
The Journal of Organic Chemistry, ISSN 0022-3263, 01/2013, Volume 78, Issue 2, pp. 212 - 223
A straightforward, easy, and practical access to various amino acid analogues (methionine, leucine, lysine, and arginine) from a unique fluorinated... 
POTENT | DESIGN | (2S,3S)-2,3-METHANOMETHIONINE | CHEMISTRY, ORGANIC | INHIBITORS | QUINOLONECARBOXYLIC ACID | NEW-GENERATION | DERIVATIVES | RECEPTOR ANTAGONIST | PROTEASE | MGS0039 | Oligopeptides - chemical synthesis | Peptidomimetics - chemical synthesis | Amino Acids - chemistry | Hydrocarbons, Fluorinated - chemistry | Peptidomimetics - chemistry | Amino Acids - chemical synthesis | Arginine - chemistry | Leucine - chemistry | Cyclopropanes - chemistry | Methionine - chemistry | Halogenation | Molecular Structure | Oligopeptides - chemistry | Peptides | Analysis | Protein biosynthesis | Chemical properties | Research | Fluorination | Structure | Organic chemistry | Chemical Sciences
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