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Journal Article
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 11/2019, Volume 108, p. 104452
Perfluorohexane sulfonate (PFHxS) is a six-carbon perfluoroalkyl sulfonic acid that was used as an industrial surfactant, but is now found as an environmental... 
Perfluorohexane sulfonate | Reference dose | Reproductive toxicity | Perfluorohexane-1-sulfonic acid | Point of departure
Journal Article
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 10/2012, Volume 120, Issue 10, pp. 1432 - 1437
Background: Prenatal exposures to polyfluoroalkyl compounds (PFCs) may be associated with adverse changes in fetal and postnatal growth. Objective: We explored... 
Pregnancy | Chemical hazards | Body mass index | Vivipary | Menarche | Patent foramen ovale | Birth weight | Sulfonates | Epidemiology | Gestational age | Children's Health | Postnatal growth | Early childhood growth | Perfluorooctanoate | ALSPAC | Perfluorohexane sulfonate | Perfluorooctane sulfonate | Polyfluoroalkyl compounds | birth weight | CROSS-FOSTER | perfluorohexane sulfonate | polyfluoroalkyl compounds | MOUSE | SULFONATE | SERUM | perfluorooctanoate | NATIONAL BIRTH COHORT | DEVELOPMENTAL TOXICITY | postnatal growth | ENVIRONMENTAL SCIENCES | PERFLUOROOCTANOIC ACID | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | perfluorooctane sulfonate | PERFLUORINATED CHEMICALS | early childhood growth | EXPOSURE | AGE | Fluorocarbons - toxicity | Multivariate Analysis | Age Factors | Birth Weight - drug effects | Prenatal Exposure Delayed Effects - epidemiology | Humans | Body Weight - drug effects | Infant | Maternal Exposure | Environmental Pollutants - blood | Fluorocarbons - blood | England - epidemiology | Alkanesulfonic Acids - blood | Female | Environmental Pollutants - toxicity | Child | Infant, Newborn | Environmental Monitoring | Caprylates - toxicity | Sulfonic Acids - blood | Fetal Development - drug effects | Sulfonic Acids - toxicity | Gestational Age | Regression Analysis | Adolescent | Alkanesulfonic Acids - toxicity | Longitudinal Studies | Caprylates - blood | Prenatal Exposure Delayed Effects - chemically induced | Cohort Studies | Complications and side effects | Research | Child development | Health aspects | Smoking in pregnancy | Organic compounds | Index Medicus | Confidence intervals | Exposure | Birth | Serums | Girls
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 08/2018, Volume 118, pp. 490 - 504
Seafood consumption is a major route for human exposure to environmental contaminants of emerging concern (CeCs). However, toxicological information about the... 
eicosapentaenoic aci | European commission | 3,3,5-Trimethylcyclohexylsalicylate | perfluorohexane sulfonate | DPMI | methyl mercury | BMDL | PFNA | 3-(4-Methylbenzylidene)camphor | EHS | perfluorodecane sulfonate | n-octanol/water partition coefficientLC-IT-MS/MS | perfluoroheptane sulfonate | benzo(k)fluoranthene | LOD | PFDS | total arsenic | RSD | PFCs | contaminants of emerging concern | PFTrA | TWI | European Food Safety Authority | easy | LOQ | GC-MS | 2,2-Dihydroxy-4,4-dimethoxybenzophenone | ECHA | NOAEL | ISTD | perfluoroheptanoate | DHMB | 6,7-dihydro-1,1,2,3,3-pentamethyl-4(5H)-indanone | ICP-MS | DHA | benzo(b)fluoranthene | HBGVs | dogfish muscle reference material | PFDcA | AsV | POPs | health-based guidance values | ANOVA | docosahexaenoic acid | Benzophenone 1 | Hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate | HPLC | internal standards | gas chromatography-ion trap-tandem mass spectrometr | benzo(a)pyrene | 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene | perfluorononanoate | gas chromatography-mass spectrometry | benzo(ghi)perylene | polycyclic aromatic hydrocarbons | PFOA | lead | perfluorobutanoate | Musk fragrances and UV-Filters | high performance liquid chromatography | Kow | THg | indeno(123cd)pyrene | PCPs | 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-(g)-2-benzopyran | ERM-BC211 | perfluoropentanoate | dispersive solid-phase extraction | iAs | inorganic arsenic | Sum of benzo(a)anthracene | personal care products | PFUnA | perfluorodecanoate | rice reference material | HHCB | PFOS | Octocrylene | PCBs | no observed adverse effect level | quick | perfluorotetradecanoate | total mercury | PAH8 | Steaming | dibenzo(a,h)anthracene | Seafood | perfluorobutane sulfonate | perfluorotridecanoate | dSPE | CeCs | EFSA | PFBA | PFTeA | polychlorinated biphenyls | relative standard deviation | HHCB-lactone | perfluorododecanoate | PFPeA | BP1 | tolerable daily intake | DORM-4 | margins of exposure | Cu -copper | liquid-chromatography-ion trap tandem mass spectrometry | TAs | perfluorohexanoate | MS- mass spectrometry | limit of detection | inductively coupled plasma mass spectrometer | TORT-2 | perfluorooctane sulfonate | PAH4 | cadmium | perfluoroctanoate | PAH2 | benchmark dose lower limit | mercury | 4-MBC | European chemicals agency | PFDoA | rugged and safe | GC–IT-MS/MS | BaP | DBENZO | effective | PFHxA | analysis of variance | QuEChERS | tolerable upper intake level | TDI | benz(a)anthracene | sum of benzo(a)pyrene | 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-(g)-2-benzopyran-1-one | arsenic V | chromium | MOE | PFBS | PFHxS | perfluorundecanoate | PFHpA | tolerable weekly intake | perfluorinated compounds | 2-Ethylhexyl salicylate | lobster hepatopancreas reference material | MeHg | chrysene | EPA | PAHs | persistent organic pollutants | limit of quantification | safety/uncertainty factor | PFHpS | Toxic elements | AHTN | POLYCYCLIC AROMATIC-HYDROCARBONS | FOOD SCIENCE & TECHNOLOGY | MUSK FRAGRANCES | MASS-SPECTROMETRY | COOKING PROCESSES | COOKED SEAFOOD | METALS | FISH | SHELLFISH | TOXICOLOGY | EXPOSURE | UV-FILTERS | Limit of Detection | Cooking | Risk Assessment | Dietary Exposure | Fatty Acids, Monounsaturated - analysis | Food Contamination - analysis | Europe | Humans | Chromatography, High Pressure Liquid | Spectrophotometry, Atomic | Ultraviolet Rays | Mass Spectrometry | Polycyclic Aromatic Hydrocarbons - analysis | Metals, Heavy - analysis | Seafood - analysis | Fluorocarbons - analysis | Safety and security measures | Analysis | Contamination | Food
Journal Article
Toxicological Sciences, ISSN 1096-6080, 03/2017, Volume 156, Issue 1, pp. 84 - 95
Perfluoroalkyl sulfonates (PFSAs) such as perfluorohexane sulfonate (PFHxS) and perfluorooctane sulfonate (PFOS) have very long serum elimination half-lives in... 
Perfluorobutane sulfonate | Perfluorohexane sulfonate | Perfluorooctane sulfonate | Perfluoroalkyl sulfonates | Perfluoroalkyl carboxylates | perfluorohexane sulfonate | perfluorobutane sulfonate | OATP-B | ELIMINATION | perfluoroalkyl carboxylates | EXCRETION | PERFLUOROOCTANOIC ACID | perfluorooctane sulfonate | MOLECULAR-IDENTIFICATION | TISSUE DISTRIBUTION | LIVER | COMPARATIVE PHARMACOKINETICS | MICE | TOXICOLOGY | MONKEYS | perfluoroalkyl sulfonates | Organic Anion Transporters, Sodium-Independent - genetics | Solute Carrier Organic Anion Transporter Family Member 1B3 - metabolism | Cricetulus | Humans | Fluorocarbons - metabolism | Rats | Environmental Pollutants - metabolism | Hepatocytes - metabolism | Caprylates - metabolism | Recombinant Fusion Proteins - metabolism | Sulfonic Acids - metabolism | Organic Anion Transporters - metabolism | Organic Anion Transporters - genetics | Animals | Biological Transport | Organic Anion Transporters, Sodium-Independent - metabolism | Solute Carrier Organic Anion Transporter Family Member 1b1 - metabolism | HEK293 Cells | Alkanesulfonic Acids - metabolism | CHO Cells | Solute Carrier Organic Anion Transporter Family Member 1B3 - genetics | Solute Carrier Organic Anion Transporter Family Member 1b1 - genetics | Index Medicus | Perfluoroalkyl ACID Transport via Organic Anion Transporter Polypeptides
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 02/2014, Volume 122, Issue 2, pp. 187 - 192
The presence of perfluoroalkyl acids (PFAAs) in breast milk has been documented, but their lactational transfer has been rarely studied. Determination of the... 
and infants | concentrations of perfluorooctanoic acid (PFOA) | Background: The presence of perfluoroalkyl acids (PFAAs) in breast milk has been documented | C onclusions: Breast milk is the optimal food for infants | 0%). The infant PFOA and PFOS serum concentrations | and PFHxS (-1 | perfluorononanoic | 7%) higher per month of breastfeeding | and perfluorohexane sulfonate (PFHxS). For a subset of the population | HUMAN-MILK | PLASMA | perfluorooctane sulfonate (PFOS) | O b jectives: We aimed to investigate the association between breastfeeding and maternal serum | infant serum PFAA concentrations | acid (PFNA) | 95% CI | breastfeeding at the time of survey. PFAA serum concentrations were available for all mothers and | of PFOA (-3 | lactating mothers and exposure route for nursing infants | 1 | WOMEN | 2 | a child < 3.5 years of age and who provided blood samples and reported detailed information on | we investigated associations of breastfeeding with | Methods: The present analysis included 633 women from the C8 Science Panel Study who had | PERFLUORINATED COMPOUNDS | LACTATION | for | PFOS (-3 | 8% (n=49) of the infants. Maternal and infant serum concentrations were regressed on duration of | but their lactational transfer has been rarely studied. Determination of the elimination rates of | ETHERS | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | CHEMICALS | PFNA (-2 | were 6% (95% CI: 1 | TOXICOLOGY | 10%) and 4% (95% CI: 1 |