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Development, ISSN 0950-1991, 07/2011, Volume 138, Issue 13, pp. 2673 - 2680
In peripheral nerves, Schwann cells form the myelin sheath that insulates axons and allows rapid propagation of action potentials. Although a number of... 
Gpr126 | Mouse | Myelin | Schwann cell | SYSTEM | CLAW-PAW MUTATION | DEVELOPMENTAL BIOLOGY | GLIAL-CELLS | DESERT-HEDGEHOG | CYCLIC-AMP | PROTEIN-COUPLED RECEPTOR | TRANSCRIPTION FACTOR SOX10 | GENE-EXPRESSION | SCHWANN-CELL DIFFERENTIATION | Immunohistochemistry | Peripheral Nerves - ultrastructure | Cochlear Nerve - ultrastructure | Receptors, G-Protein-Coupled - metabolism | Early Growth Response Protein 2 - genetics | Octamer Transcription Factor-6 - genetics | Cochlear Nerve - metabolism | Myelin Basic Protein - genetics | Octamer Transcription Factor-6 - metabolism | Peripheral Nerves - metabolism | Peripheral Nervous System Diseases - genetics | Microscopy, Electron, Transmission | Myelin Basic Protein - metabolism | Cochlear Nerve - abnormalities | Schwann Cells - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Peripheral Nerves - pathology | Mice, Knockout | Peripheral Nervous System Diseases - metabolism | Animals | Myelin P0 Protein - genetics | Early Growth Response Protein 2 - metabolism | Mice | Receptors, G-Protein-Coupled - genetics | Myelin P0 Protein - metabolism | Peripheral Nerves - growth & development | Index Medicus | Peripheral nerves | Schwann cells | perineurium | Action potential | Peripheral neuropathy | Myelin basic protein | EGR-2 protein | Axons | Signal transduction | Myelination | Fibroblasts | Mutation | Myelin P0 protein | Sciatic nerve
Journal Article
Development (Cambridge), ISSN 0950-1991, 09/2017, Volume 144, Issue 17, pp. 3114 - 3125
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2007, Volume 27, Issue 46, pp. 12565 - 12576
Toll-like receptors (TLRs) bind specific components conserved among microorganisms as well as endogenous ligands produced by necrotic cells, injured axons, and... 
Zymosan | Lipopolysaccharide | Macrophages | Myelin inhibitors | Sciatic nerve | Axonal regeneration | axonal regeneration | myelin inhibitors | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | RAT SCIATIC-NERVE | AUTOIMMUNE-MEDIATED DEMYELINATION | NEUROSCIENCES | FACTOR-ALPHA | RETINAL GANGLION-CELLS | macrophages | TUMOR-NECROSIS-FACTOR | zymosan | SPINAL-CORD-INJURY | SCHWANN-CELLS | GROWTH-FACTOR | lipopolysaccharide | sciatic nerve | INNATE IMMUNITY | Toll-Like Receptor 2 - agonists | Toll-Like Receptor 2 - genetics | Immunity, Innate - genetics | Phagocytosis - genetics | Myelin Sheath - metabolism | Chemotaxis, Leukocyte - genetics | Interleukin-1beta - metabolism | Nerve Fibers, Myelinated - pathology | Toll-Like Receptor 4 - agonists | Chemokine CCL2 - metabolism | Peripheral Nerves - metabolism | Toll-Like Receptors - metabolism | Macrophages - immunology | Wallerian Degeneration - genetics | Nerve Fibers, Myelinated - metabolism | Nerve Regeneration - genetics | Recovery of Function - genetics | Wallerian Degeneration - metabolism | Mice, Inbred C57BL | Wallerian Degeneration - physiopathology | Rats | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Toll-Like Receptors - agonists | Mice, Knockout | Peripheral Nerves - physiopathology | Macrophages - metabolism | Animals | Toll-Like Receptors - genetics | Sciatic Neuropathy - physiopathology | Mice | Sciatic Neuropathy - metabolism | Peripheral Nerve Injuries | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 05/2016, Volume 6, Issue 1, pp. 25663 - 25663
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e47977 - e47977
In recent years a growing debate is about whether botulinum neurotoxins are retrogradely transported from the site of injection. Immunodetection of cleaved... 
TOXIN-A | ACIDIC PROTEIN GFAP | RAT | MULTIDISCIPLINARY SCIENCES | ANIMAL-MODELS | CULTURED ASTROCYTES | SPINAL-CORD | AXONAL-TRANSPORT | NERVE CONSTRICTION | GLIAL-CELLS | SNAP-25 | Immunohistochemistry | Analgesics - pharmacology | Sciatic Nerve - injuries | Spinal Cord - drug effects | Spinal Cord - metabolism | Neuralgia - metabolism | Analgesics - metabolism | Male | Acetylcholine - metabolism | Glial Fibrillary Acidic Protein - metabolism | Botulinum Toxins, Type A - pharmacology | Hindlimb - physiopathology | Sciatic Nerve - metabolism | Biological Transport | Neuralgia - prevention & control | Neuromuscular Agents - pharmacology | Peripheral Nerves - metabolism | Schwann Cells - drug effects | Neuromuscular Agents - metabolism | Cells, Cultured | Nuclear Proteins - metabolism | Schwann Cells - metabolism | Nerve Tissue Proteins - metabolism | Microscopy, Confocal | Animals | Hindlimb - drug effects | Cell Proliferation - drug effects | Mice | Synaptosomal-Associated Protein 25 - metabolism | Botulinum Toxins, Type A - metabolism | CD11b Antigen - metabolism | Hindlimb - metabolism | Astrocytes - metabolism | Ganglia, Spinal - metabolism | Care and treatment | Analysis | Pain | Cell proliferation | Spinal cord | Neurosciences | Complement receptor 3 | Neurobiology | SNAP receptors | Biology | Neuropathy | Proteins | Biological effects | Dorsal root ganglia | Analgesics | Animal tissues | Fibroblasts | Neurotoxin A | Horns | Growth factors | Nerve endings | CD11b antigen | Neurotoxins | Pain perception | Astrocytes | Glial fibrillary acidic protein | Schwann cells | Injection | Retrograde transport | Botulinum toxin | Ganglia | Quality of life | Councils | SNAP-25 protein | Acetylcholine | Toxins | Transport | Immunofluorescence | Sciatic nerve | Combinatorial analysis | Index Medicus
Journal Article
Neuroscience, ISSN 0306-4522, 2015, Volume 313, pp. 10 - 22
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 03/2015, Volume 23, Issue 3, pp. 423 - 433
Journal Article
Annals of Neurology, ISSN 0364-5134, 02/2014, Volume 75, Issue 2, pp. 255 - 265
Journal Article
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 05/2018, Volume 365, Issue 2, pp. 336 - 345
Little is known about the impact of the blood-nerve barrier (BNB) on drug distribution into peripheral nerves. In this study, we examined the peripheral nerve... 
SYSTEM | PERMEABILITY | PENETRATION | PHARMACOLOGY & PHARMACY | MODEL | DORSAL-ROOT-GANGLIA | BLOOD-BRAIN-BARRIER | BINDING | DISCOVERY | CANCER RESISTANCE PROTEIN | P-GLYCOPROTEIN | Pharmaceutical Preparations - metabolism | Animals | Rats | Male | Peripheral Nerves - metabolism | Small Molecule Libraries - metabolism | Rats, Sprague-Dawley | Index Medicus
Journal Article
Neurology, ISSN 0028-3878, 05/2017, Volume 88, Issue 22, pp. 2128 - 2131
OBJECTIVE:To test if phosphorylated α-synuclein (p-α-syn) deposits can be detected by means of skin biopsy in patients with idiopathic REM sleep behavior... 
NEURODEGENERATIVE DISEASE | RISK | PATHOLOGY | CLINICAL NEUROLOGY | PARKINSON DISEASE | Cervical Vertebrae | Phosphorylation | Skin - metabolism | Humans | Middle Aged | Male | Polysomnography | REM Sleep Behavior Disorder - pathology | Peripheral Nerves - pathology | Leg | Biopsy | Fluorescent Antibody Technique |