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Acta Neuropathologica, ISSN 0001-6322, 2011, Volume 121, Issue 3, pp. 397 - 405
Missense mutations of the V600E type constitute the vast majority of tumor-associated somatic alterations in the v-RAF murine sarcoma viral oncogene homolog B1... 
Brain tumor | Pathology | Neurosciences | Ganglioglioma | V600E mutation | Medicine & Public Health | BRAF | Pleomorphic xanthoastrocytoma | GLIOMAS | B-RAF GENE | PATHOLOGY | CANCER | NEUROSCIENCES | CLINICAL NEUROLOGY | PATHWAY ACTIVATION | ATYPICAL TERATOID/RHABDOID TUMOR | COMPONENT | DUPLICATION | INHIBITOR | MAPK PATHWAY | EXPRESSION | Astrocytoma - genetics | Gene Frequency - genetics | World Health Organization | Signal Transduction | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Child, Preschool | Exons - genetics | Mutation, Missense - genetics | Young Adult | Ganglioglioma - genetics | Astrocytoma - pathology | Proto-Oncogene Proteins B-raf - genetics | Ganglioglioma - pathology | Adolescent | Adult | Nervous System Neoplasms - genetics | Retrospective Studies | Child | Nervous System Neoplasms - pathology | Medical colleges | Molecular genetics | Sarcoma | Neurons | Brain tumors | Oncology, Experimental | Melanoma | Thyroid diseases | Research | Codon | Gene mutations | Gliomas | Analysis | Genetic research | Genetic aspects | Cancer | meningioma | Pediatrics | Exons | Glioblastoma | Clinical trials | Insertion | Adenoma | Neuronal-glial interactions | Missense mutation | Sheaths | Colon | Astrocytoma | Oncogenes | Peripheral nervous system | Astrocytes | Base pairs | Central nervous system diseases | Glioma | Pituitary | Codons | papillary thyroid carcinoma | Tumors
Journal Article
Pediatric Neurosurgery, ISSN 1016-2291, 08/2013, Volume 48, Issue 5, pp. 271 - 285
There are several genetic syndromes that predispose to the development of tumors of the nervous system. In the present study, we provide a review of the tumors... 
Review | Tumor | Genetic syndromes | Peripheral nervoussystem | Central nervous system | Peripheral nervous system | GLIOMAS | SURGERY | CELL CARCINOMA SYNDROME | SUPPRESSOR GENE | DESMOPLASTIC MEDULLOBLASTOMA | LHERMITTE-DUCLOS-DISEASE | HIPPEL-LINDAU-DISEASE | SHEATH TUMORS | CLINICAL NEUROLOGY | PATHOGENESIS | TUBEROUS SCLEROSIS COMPLEX | PEDIATRICS | NEUROFIBROMATOSIS TYPE-1 | Neurofibromatosis 1 - epidemiology | Colorectal Neoplasms - genetics | Humans | Li-Fraumeni Syndrome - diagnosis | Colorectal Neoplasms - diagnosis | von Hippel-Lindau Disease - diagnosis | Li-Fraumeni Syndrome - genetics | Neoplastic Syndromes, Hereditary - epidemiology | Neoplastic Syndromes, Hereditary - genetics | Tuberous Sclerosis - diagnosis | Li-Fraumeni Syndrome - epidemiology | Neurofibromatosis 1 - genetics | Peripheral Nervous System Neoplasms - epidemiology | Colorectal Neoplasms - epidemiology | Tuberous Sclerosis - epidemiology | Brain Neoplasms - diagnosis | Central Nervous System Neoplasms - genetics | von Hippel-Lindau Disease - epidemiology | Brain Neoplasms - genetics | Neoplastic Syndromes, Hereditary - diagnosis | Neurofibromatosis 1 - diagnosis | Peripheral Nervous System Neoplasms - diagnosis | von Hippel-Lindau Disease - genetics | Central Nervous System Neoplasms - epidemiology | Syndrome | Tuberous Sclerosis - genetics | Animals | Central Nervous System Neoplasms - diagnosis | Peripheral Nervous System Neoplasms - genetics | Brain Neoplasms - epidemiology | Surgical outcomes | Pediatrics | Genetic disorders | Neurosurgery | Tumors
Journal Article
2014, ISBN 9780702040887, Volume 121
Book Chapter
Advances In Anatomic Pathology, ISSN 1072-4109, 05/2018, Volume 25, Issue 5, pp. 353 - 368
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2013, Volume 123, Issue 1, pp. 340 - 347
Neurofibromatosis type 1 (NF1) patients develop benign neurofibromas and malignant peripheral nerve sheath tumors (MPNST). These incurable peripheral nerve... 
MEDICINE, RESEARCH & EXPERIMENTAL | SIGNALING PATHWAYS | PLEXIFORM NEUROFIBROMAS | GENOMIC ANALYSES | THERAPEUTIC TARGET | NF1 | SCHWANN-CELLS | HYPERACTIVE RAS | CANCER | NERVE SHEATH TUMORS | PREVIOUSLY TREATED PATIENTS | Neoplasm Transplantation | Mitogen-Activated Protein Kinase Kinases - genetics | Diphenylamine - pharmacology | Humans | Child, Preschool | Male | Transplantation, Heterologous | Extracellular Signal-Regulated MAP Kinases - metabolism | raf Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Oncogene Protein p21(ras) - metabolism | Diphenylamine - analogs & derivatives | Mitogen-Activated Protein Kinase Kinases - metabolism | Peripheral Nervous System Neoplasms - enzymology | Mice, Mutant Strains | Female | Benzamides - pharmacology | Neurofibromatosis 1 - genetics | Peripheral Nervous System Neoplasms - pathology | raf Kinases - genetics | Child | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Peripheral Nervous System Neoplasms - drug therapy | Transcriptome - drug effects | Transcriptome - genetics | Xenograft Model Antitumor Assays | Neurofibromatosis 1 - enzymology | Neurofibromatosis 1 - pathology | Animals | Neurofibromatosis 1 - drug therapy | Mice | Peripheral Nervous System Neoplasms - genetics | Oncogene Protein p21(ras) - genetics | Physiological aspects | Causes of | Neural stimulation | Enzyme inhibitors | Properties | Neurofibromatosis
Journal Article
Seminars in Immunopathology, ISSN 1863-2297, 1/2012, Volume 34, Issue 1, pp. 43 - 62
The interaction of coagulation factors with the perivascular environment affects the development of disease in ways that extend beyond their traditional roles... 
Autoimmunity | Complement receptor 3 | Multiple sclerosis | Stroke | Alzheimer’s disease | Internal Medicine | Macrophages | Blood brain barrier | Inflammatory disease | Microglia | Biomedicine | Immunology | Rheumatoid arthritis | CD11b/CD18 | Atherosclerosis | Plasminogen | Anticoagulant therapy | Alzheimer's disease | ALZHEIMERS-DISEASE | IMMUNOLOGY | PATHOLOGY | GAMMA-C-DOMAIN | BINDING-SITE | CENTRAL-NERVOUS-SYSTEM | MULTIPLE-SCLEROSIS LESIONS | CRYSTAL-STRUCTURE | BLOOD-BRAIN-BARRIER | INTEGRIN ALPHA(M)BETA | PROTEASE-ACTIVATED RECEPTORS | PERIPHERAL ARTERIAL-DISEASE | Colitis - genetics | Humans | Brain Injuries - metabolism | Arthritis, Rheumatoid - metabolism | Bacterial Infections - genetics | Inflammation - metabolism | Blood Coagulation - immunology | Muscular Dystrophy, Duchenne - immunology | Alzheimer Disease - immunology | Fibrinogen - immunology | Thromboplastin - immunology | Pulmonary Fibrosis - immunology | Vascular Diseases - genetics | Brain Injuries - genetics | Thrombin - genetics | Kidney Diseases - immunology | Arthritis, Rheumatoid - genetics | Neoplasms - immunology | Colitis - metabolism | Muscular Dystrophy, Duchenne - genetics | Bacterial Infections - metabolism | Neoplasms - metabolism | Pulmonary Fibrosis - genetics | Spinal Cord Injuries - genetics | Kidney Diseases - genetics | Stroke - genetics | Brain Injuries - immunology | Neoplasms - genetics | Bacterial Infections - immunology | Pulmonary Fibrosis - metabolism | Colitis - immunology | Thrombin - immunology | Stroke - immunology | Kidney Diseases - metabolism | Multiple Sclerosis - metabolism | Vascular Diseases - immunology | Spinal Cord Injuries - metabolism | Multiple Sclerosis - genetics | Inflammation - immunology | Fibrinogen - genetics | Stroke - metabolism | Animals | Thromboplastin - genetics | Alzheimer Disease - metabolism | Fibrinogen - metabolism | Inflammation - genetics | Multiple Sclerosis - immunology | Blood Coagulation - genetics | Spinal Cord Injuries - immunology | Muscular Dystrophy, Duchenne - metabolism | Thrombin - metabolism | Thromboplastin - metabolism | Alzheimer Disease - genetics | Arthritis, Rheumatoid - immunology | Vascular Diseases - metabolism | Nervous system diseases | Bacterial infections | Oncology, Experimental | Thrombin | Inflammation | Anticoagulants (Medicine) | Research | Rheumatoid factor | Fibrin | Fibrinogen | Genetic research | Colitis | Cancer | Traumatic brain injury | Coagulation | Tissue factor | hemostasis | Spinal cord injury | Inflammatory diseases | Kidney | Signal transduction | Duchenne's muscular dystrophy | Neurodegenerative diseases | Therapeutic applications | Thrombosis | Coagulation factors | Infection | Molecular modelling | Fibrosis | Brain injury
Journal Article
2005, ISBN 0721681484
This new resource presents today's most comprehensive, multidisciplinary coverage of cancers of the central and peripheral nervous system. Experts in... 
Book
Lancet Oncology, The, ISSN 1470-2045, 2014, Volume 15, Issue 8, pp. 819 - 828
Summary Background Gemcitabine plus a platinum-based agent (eg, cisplatin or oxaliplatin) is the standard of care for advanced biliary cancers. We investigated... 
Hematology, Oncology and Palliative Medicine | GROWTH-FACTOR RECEPTOR | MULTICENTER | CISPLATIN | ONCOLOGY | COLORECTAL-CANCER | CLINICAL-TRIALS | GALLBLADDER | COMBINATION | TUMORS | CHEMOTHERAPY | GALL-BLADDER CANCER | ras Proteins - genetics | Peripheral Nervous System Diseases - chemically induced | Proto-Oncogene Proteins p21(ras) | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Alanine Transaminase - blood | Organoplatinum Compounds - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Oxaliplatin | Common Bile Duct Neoplasms - drug therapy | Adult | Bile Ducts, Intrahepatic | Female | Bile Duct Neoplasms - genetics | Cetuximab | Neutropenia - chemically induced | Common Bile Duct Neoplasms - genetics | Bile Duct Neoplasms - drug therapy | Carcinoma - drug therapy | Antibodies, Monoclonal, Humanized - adverse effects | Deoxycytidine - administration & dosage | Gallbladder Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Disease-Free Survival | Gallbladder Neoplasms - drug therapy | Aspartate Aminotransferases - blood | Cholangiocarcinoma - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Intention to Treat Analysis | Cholangiocarcinoma - genetics | Carcinoma - genetics | Aged | Mutation | Deoxycytidine - analogs & derivatives | Chemotherapy | Product development | Gemcitabine | Comparative analysis | Cancer
Journal Article