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Acta Biomaterialia, ISSN 1742-7061, 09/2016, Volume 41, pp. 273 - 281
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, pp. e0160141 - e0160141
.... granulomas) that slowly invades the bone-implant interface, leading to bone resorption and eventual painful loosening of the implant [4-7]. This slow inflammatory... 
IN-VITRO | STIMULATION | MULTIDISCIPLINARY SCIENCES | WEAR PARTICLES | IONS | PERIPROSTHETIC OSTEOLYSIS | PERIPHERAL-BLOOD MONOCYTES | RELEASE | RECEPTOR 4 | EXPRESSION | NALP3 INFLAMMASOME | Inflammation - chemically induced | Tumor Necrosis Factor-alpha - metabolism | Osteoporosis - chemically induced | Humans | Mice, Inbred C57BL | Prostheses and Implants | Male | Monocytes - metabolism | Toll-Like Receptor 4 - metabolism | Monocytes - drug effects | Macrophages - metabolism | Animals | Signal Transduction - drug effects | Interleukin-1beta - metabolism | Toll-Like Receptor 4 - agonists | Macrophages - drug effects | Mice | Alloys - adverse effects | Cobalt - adverse effects | Physiological aspects | Causes of | Inflammation | Research | Macrophages | Cobalt alloys | Surgical implants | Animal models | Transplants & implants | Toxicity | Metals | Homeostasis | Activation | Joint surgery | Osteolysis | Cobalt | Lipopolysaccharides | Interleukin 6 | Proteins | Receptors | Biomedical materials | Moisture content | Penicillin | Toll-like receptors | Bacteria | Tumor necrosis factor-TNF | Biocompatibility | Gram-negative bacteria | Bone loss | Debris | Immune system | Cytokines | Detritus | Histology | Hazards | Pattern recognition | TLR4 protein | Tumor necrosis factor-α | Gene expression | Heavy metals | Studies | Cobalt base alloys | Signaling | Calvaria | Interleukin 10 | Hypoxia | Sepsis | Nickel | Laboratory animals | Index Medicus
Journal Article
BMC musculoskeletal disorders, ISSN 1471-2474, 2017, Volume 18, Issue 1, pp. 383 - 7
Background: Hip and knee replacements in patients with bone defects after infection correlates with high rates of reinfection... 
Bone defects | Periimplant infection | Modular mega-endoprostheses | Reinfection | Silver-coated implants | SURVIVAL | MEGAPROSTHESES | TUMOR RESECTION | KNEE ARTHROPLASTY | ENDOPROSTHETIC REPLACEMENT | RECONSTRUCTION | RHEUMATOLOGY | FEMUR | TOTAL HIP | MALIGNANT-TUMOR | ORTHOPEDICS | PERIPROSTHETIC JOINT INFECTIONS | Arthroplasty, Replacement, Knee - trends | Arthroplasty, Replacement, Knee - adverse effects | Follow-Up Studies | Humans | Middle Aged | Reoperation - trends | Male | Femur - diagnostic imaging | Silver - administration & dosage | Reoperation - methods | Aged, 80 and over | Salvage Therapy - trends | Adult | Female | Prosthesis-Related Infections - diagnostic imaging | Femur - surgery | Retrospective Studies | Arthroplasty, Replacement, Hip - trends | Tibia - diagnostic imaging | Arthroplasty, Replacement, Hip - adverse effects | Tibia - surgery | Prosthesis-Related Infections - surgery | Pilot Projects | Aged | Salvage Therapy - methods | Infection | Prevention | Orthopedic implants | Usage | Orthopedic surgery | Patient outcomes | Physiological aspects | Research | Risk factors | Methods | Knee | Prostheses | Femur | Transplants & implants | Prophylaxis | Mobility | Infections | Arthroplasty | Joint surgery | Joint diseases | Patients | Trauma | Hip | Nanoparticles | Silver | Biomedical materials | Biofilms | Antibiotics | Tibia | Surgery | Bone loss
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 117, pp. 1 - 9
Journal Article
Journal of the American Academy of Orthopaedic Surgeons, ISSN 1067-151X, 2013, Volume 21, Issue 10, pp. 601 - 612
.... Each of these conditions may be associated with mild or advanced bone loss. Careful patient evaluation and bone loss classification guide preoperative planning and overall patient care... 
SURGERY | ORTHOPEDICS | Radiography | Periprosthetic Fractures - diagnosis | Reoperation | Prosthesis Failure | Periprosthetic Fractures - etiology | Humans | Hip Prosthesis | Periprosthetic Fractures - surgery | Femur - surgery | Femur - diagnostic imaging | Arthroplasty, Replacement, Hip - adverse effects | Osteoporosis | Femur | Care and treatment | Diagnosis
Journal Article
Journal Article
Journal Article
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 4/2011, Volume 469, Issue 4, pp. 1016 - 1023
Revision of the infected hip arthroplasty with major bone loss is difficult. Attempts to restore bone stock with structural allograft are controversial.We assessed the (1) reinfection rate; (2) rerevision rate; (3... 
Surgical Orthopedics | Medicine & Public Health | Sports Medicine | Surgery | Orthopedics | Conservative Orthopedics | Medicine/Public Health, general | SURGERY | PROSTHESIS COMPOSITE | EXCISION ARTHROPLASTY | REVISION HIP | RECONSTRUCTION | ACETABULAR REVISION | FOLLOW-UP | 2-STAGE REVISION | ORTHOPEDICS | PROXIMAL FEMORAL ALLOGRAFTS | CUP | MEGAPROSTHESIS | Foreign-Body Migration - etiology | Osseointegration | Recurrence | Humans | Middle Aged | Male | Hip Joint - microbiology | Infection Control - methods | Recovery of Function | Transplantation, Homologous | Prosthesis-Related Infections - microbiology | Time Factors | Range of Motion, Articular | Aged, 80 and over | Adult | Female | Prosthesis-Related Infections - diagnostic imaging | Retrospective Studies | Bone Resorption - etiology | Reoperation | Hip Joint - surgery | Hip Prosthesis | Kaplan-Meier Estimate | Arthroplasty, Replacement, Hip - instrumentation | Treatment Outcome | Arthroplasty, Replacement, Hip - adverse effects | Hip Joint - diagnostic imaging | Radiography | Prosthesis-Related Infections - surgery | Bone Transplantation | Hip Joint - physiopathology | Aged | Ontario | Transplantation of organs, tissues, etc | Arthroplasty | Orthopedic surgery | Health aspects | Bone grafts | Femur | Migration | Acetabulum | Arthroplasty (hip) | Data processing | Nonunion | Bone surgery | Survival | Hip | Dislocation | Allografts | Bone implants | Bone loss | Injuries | Sciatic nerve | Periprosthetic Joint Infection | Symposium
Journal Article
Geriatric orthopaedic surgery & rehabilitation, ISSN 2151-4593, 2019, Volume 10, p. 215145931984739
Introduction: Management of periprosthetic infection in total hip arthroplasties is challenging, especially when there is severe loss of proximal femoral bone stock... 
reimplantation | SURGERY | periprosthetic joint infection | revision hip replacement | REHABILITATION | articulating spacer | ORTHOPEDICS | proximal femur bone loss | HIP | GERIATRICS & GERONTOLOGY | Antibiotics
Journal Article
F1000 research, ISSN 2046-1402, 2014, Volume 2, p. 266
.... Clinical longevity of implants depends on their osseointegration, which is influenced by the load, the characteristics of the implant and the bone-implant interface, as well as by the... 
Bone Biology, Osteoporosis & Other Diseases of Bone
Journal Article