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1. Full Text Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial
by Swisher, Elizabeth M, Dr Prof and Lin, Kevin K, PhD and Oza, Amit M, Prof and Scott, Clare L, PhD and Giordano, Heidi, MA and Sun, James, PhD and Konecny, Gottfried E, MD and Coleman, Robert L, Prof and Tinker, Anna V, MD and O'Malley, David M, MD and Kristeleit, Rebecca S, MD and Ma, Ling, MD and Bell-McGuinn, Katherine M, MD and Brenton, James D, Prof and Cragun, Janiel M, MD and Oaknin, Ana, MD and Ray-Coquard, Isabelle, Prof and Harrell, Maria I, PhD and Mann, Elaina, MS and Kaufmann, Scott H, Prof and Floquet, Anne, MD and Leary, Alexandra, MD and Harding, Thomas C, PhD and Goble, Sandra, MS and Maloney, Lara, BA and Isaacson, Jeff, PhD and Allen, Andrew R, MD and Rolfe, Lindsey, MBChB and Yelensky, Roman, PhD and Raponi, Mitch, PhD and McNeish, Iain A, Prof
The lancet oncology, ISSN 1470-2045, 2016, Volume 18, Issue 1, pp. 75 - 87
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Prognosis | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Ovarian Neoplasms - pathology | Salvage Therapy | Neoplasm Recurrence, Local - drug therapy | Germ-Line Mutation - genetics | Neoplasm Recurrence, Local - pathology | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Peritoneal Neoplasms - drug therapy | Fallopian Tube Neoplasms - genetics | Female | Antineoplastic Agents - pharmacology | Poly(ADP-ribose) Polymerases - chemistry | Ovarian Neoplasms - drug therapy | Platinum - pharmacology | Fallopian Tube Neoplasms - drug therapy | Peritoneal Neoplasms - pathology | Neoplasms, Glandular and Epithelial - pathology | Fallopian Tube Neoplasms - pathology | Survival Rate | Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use | BRCA1 Protein - genetics | International Agencies | Peritoneal Neoplasms - genetics | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Indoles - therapeutic use | Neoplasm Recurrence, Local - genetics | Aged | Neoplasm Staging | BRCA2 Protein - genetics | Drug Resistance, Neoplasm - drug effects | Sugars | Monosaccharides | Ovarian cancer | Analysis | Carcinoma | Cancer | Index Medicus
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2. Full Text Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship
by Kindelberger, David W and Lee, Yonghee and Miron, Alexander and Hirsch, Michelle S and Feltmate, Colleen and Medeiros, Fabiola and Callahan, Michael J and Garner, Elizabeth O and Gordon, Robert W and Birch, Chandler and Berkowitz, Ross S and Muto, Michael G and Crum, Christopher P
The American journal of surgical pathology, ISSN 0147-5185, 02/2007, Volume 31, Issue 2, pp. 161 - 169
Serous carcinoma | BRCA | Fallopian tube neoplasms | Ovarian neoplasms | Intraepithelial carcinoma | Pathology | Life Sciences & Biomedicine | Surgery | Science & Technology | Biological and medical sciences | Investigative techniques, diagnostic techniques (general aspects) | Medical sciences | Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques | Humans | Cystadenocarcinoma, Serous - metabolism | Ovarian Neoplasms - pathology | Cystadenocarcinoma, Serous - genetics | Cystadenocarcinoma, Serous - pathology | Ovarian Neoplasms - genetics | Carcinoma in Situ - genetics | Fallopian Tube Neoplasms - genetics | Female | Ovarian Neoplasms - metabolism | Neoplasms, Second Primary - genetics | Pelvic Neoplasms - pathology | Peritoneal Neoplasms - pathology | Carcinoma in Situ - pathology | Pelvic Neoplasms - genetics | Tumor Suppressor Protein p53 - metabolism | Fallopian Tube Neoplasms - pathology | Genes, p53 - genetics | Neoplasms, Second Primary - metabolism | Peritoneal Neoplasms - genetics | Peritoneal Neoplasms - metabolism | Fallopian Tube Neoplasms - metabolism | Mutation | Carcinoma in Situ - metabolism | Precancerous Conditions | Neoplasms, Second Primary - pathology | Index Medicus
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3. Full Text Data set for reporting of ovary, fallopian tube and primary peritoneal carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR)
by McCluggage, W. Glenn and Judge, Meagan J and Clarke, Blaise A and Davidson, Ben and Gilks, C. Blake and Hollema, Harry and Ledermann, Jonathan A and Matias-Guiu, Xavier and Mikami, Yoshiki and Stewart, Colin J. R and Vang, Russell and Hirschowitz, Lynn and International Collaboration on Cancer Reporting
Modern pathology, ISSN 0893-3952, 08/2015, Volume 28, Issue 8, pp. 1101 - 1122
Life Sciences & Biomedicine | Pathology | Science & Technology | Predictive Value of Tests | Humans | Ovarian Neoplasms - pathology | Immunohistochemistry - standards | Carcinoma - chemistry | Peritoneal Neoplasms - chemistry | Ovarian Neoplasms - genetics | Peritoneal Neoplasms - drug therapy | Neoplasm Grading | Fallopian Tube Neoplasms - chemistry | Fallopian Tube Neoplasms - genetics | Female | Molecular Diagnostic Techniques - standards | Neoadjuvant Therapy | Chemotherapy, Adjuvant | Carcinoma - pathology | Ovarian Neoplasms - drug therapy | Fallopian Tube Neoplasms - drug therapy | Carcinoma - drug therapy | Peritoneal Neoplasms - pathology | Pathology, Clinical - standards | Diagnosis, Differential | Ovarian Neoplasms - chemistry | Biopsy - standards | Biomarkers, Tumor - analysis | Carcinoma - surgery | Peritoneal Neoplasms - surgery | Fallopian Tube Neoplasms - pathology | Fallopian Tube Neoplasms - surgery | Peritoneal Neoplasms - genetics | Carcinoma - genetics | Research Design - standards | Biomarkers, Tumor - genetics | Neoplasm Staging | Ovarian Neoplasms - surgery | Index Medicus
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4. Full Text Refining the selection of patients with metastatic colorectal cancer for treatment with temozolomide using proteomic analysis of O6-methylguanine-DNA-methyltransferase
by Schwartz, Sarit and Szeto, Chris and Tian, Yuan and Cecchi, Fabiola and Corallo, Salvatore and Calegari, Maria Alessandra and Di Bartolomeo, Maria and Morano, Federica and Raimondi, Alessandra and Fucà, Giovanni and Martinetti, Antonia and De Pascalis, Ivana and Martini, Maurizio and Belfiore, Antonino and Milione, Massimo and Orlandi, Armando and Barault, Ludovic and Barone, Carlo and de Braud, Filippo and Di Nicolantonio, Federica and Benz, Steve and Hembrough, Todd and Pietrantonio, Filippo
European journal of cancer (1990), ISSN 0959-8049, 01/2019, Volume 107, pp. 164 - 174
Biomarker | Molecular diagnostics | Temozolomide | MGMT | Colorectal cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Lung Neoplasms - drug therapy | Prognosis | Follow-Up Studies | Colorectal Neoplasms - genetics | Humans | Lung Neoplasms - metabolism | Middle Aged | DNA Repair Enzymes - genetics | Neoplasm Recurrence, Local - drug therapy | Male | Biomarkers, Tumor | Patient Selection | Neoplasm Recurrence, Local - pathology | Temozolomide - therapeutic use | DNA Methylation | Peritoneal Neoplasms - drug therapy | Lung Neoplasms - secondary | Colorectal Neoplasms - drug therapy | Tumor Suppressor Proteins - genetics | DNA Repair Enzymes - metabolism | Aged, 80 and over | Female | Retrospective Studies | Liver Neoplasms - secondary | Colorectal Neoplasms - metabolism | Peritoneal Neoplasms - secondary | Lung Neoplasms - genetics | Tumor Suppressor Proteins - metabolism | DNA Modification Methylases - metabolism | Liver Neoplasms - genetics | Neoplasm Recurrence, Local - metabolism | Liver Neoplasms - drug therapy | Survival Rate | Proteome - analysis | Antineoplastic Agents, Alkylating - therapeutic use | DNA Modification Methylases - genetics | Peritoneal Neoplasms - genetics | Peritoneal Neoplasms - metabolism | Liver Neoplasms - metabolism | Neoplasm Recurrence, Local - genetics | Aged | Colorectal Neoplasms - pathology | Proteome - metabolism | Yuan (China) | Care and treatment | RNA | Transferases | Metastasis | Antineoplastic agents | Antimitotic agents | Cancer patients | Gliomas | Analysis | DNA | Genetic research | Genetic aspects | Drug therapy | Methylation | Mass spectrometry | Cancer | Index Medicus
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5. Full Text BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation–Positive Women With Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group
by Kathryn Alsop and Sian Fereday and Cliff Meldrum and Anna deFazio and Catherine Emmanuel and Joshy George and Alexander Dobrovic and Michael J. Birrer and Penelope M. Webb and Colin Stewart and Michael Friedlander and Stephen Fox and David Bowtell and Gillian Mitchell
Journal of clinical oncology, ISSN 0732-183X, 07/2012, Volume 30, Issue 21, pp. 2654 - 2663
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Biological and medical sciences | Medical sciences | Tumors | Female genital diseases | Medical History Taking | Recurrence | Prospective Studies | Humans | Middle Aged | Ovarian Neoplasms - pathology | Drug Resistance, Neoplasm | Cystadenocarcinoma, Serous - genetics | Cystadenocarcinoma, Serous - drug therapy | Case-Control Studies | Ovarian Neoplasms - genetics | Peritoneal Neoplasms - drug therapy | Neoplasm Grading | Fallopian Tube Neoplasms - genetics | Aged, 80 and over | Genes, BRCA2 | Germ-Line Mutation | Adult | Female | Genes, BRCA1 | Ovarian Neoplasms - drug therapy | Fallopian Tube Neoplasms - drug therapy | Carcinoma - drug therapy | Carcinoma, Endometrioid - genetics | Kaplan-Meier Estimate | Mutation Rate | Treatment Outcome | Carcinoma, Endometrioid - drug therapy | Australia - epidemiology | Ovarian Neoplasms - epidemiology | Disease-Free Survival | Point Mutation | Breast Neoplasms - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Peritoneal Neoplasms - genetics | Carcinoma - genetics | Aged | Platinum Compounds - administration & dosage | Neoplasm Staging | Adenocarcinoma, Clear Cell - genetics | Adenocarcinoma, Clear Cell - drug therapy | Cohort Studies | Index Medicus | Original Reports | Gynecologic Cancer | Gync21 | Gync15
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6. Full Text HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF
by Rolny, Charlotte and Mazzone, Massimiliano and Tugues, Sònia and Laoui, Damya and Johansson, Irja and Coulon, Cathy and Squadrito, Mario Leonardo and Segura, Inmaculada and Li, Xiujuan and Knevels, Ellen and Costa, Sandra and Vinckier, Stefan and Dresselaer, Tom and Åkerud, Peter and De Mol, Maria and Salomäki, Henriikka and Phillipson, Mia and Wyns, Sabine and Larsson, Erik and Buysschaert, Ian and Botling, Johan and Himmelreich, Uwe and Van Ginderachter, Jo A and De Palma, Michele and Dewerchin, Mieke and Claesson-Welsh, Lena and Carmeliet, Peter
Cancer cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 31 - 44
Clodronic Acid - pharmacology | Gene Expression - genetics | Dendritic Cells - immunology | Humans | Pregnancy Proteins - genetics | Microvessels - pathology | Pregnancy Proteins - metabolism | Chemotactic Factors - metabolism | Neoplasm Metastasis - immunology | Antibodies - immunology | Neovascularization, Pathologic - immunology | Macrophages, Peritoneal - drug effects | Macrophages - pathology | Neoplasms - blood supply | Down-Regulation - genetics | Mice, Knockout | Macrophages - metabolism | Neoplasms - immunology | Cell Line, Tumor | Placenta Growth Factor | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Macrophages, Peritoneal - metabolism | Neoplasms - metabolism | CD8-Positive T-Lymphocytes - pathology | Gene Expression - drug effects | Regional Blood Flow - genetics | Dendritic Cells - pathology | Culture Media, Conditioned - pharmacology | Lung Neoplasms - pathology | Hypoxia - metabolism | Neovascularization, Pathologic - pathology | Regional Blood Flow - drug effects | Transfection | Lung Neoplasms - secondary | Neoplasms - genetics | Dendritic Cells - metabolism | Macrophages - immunology | Lung Neoplasms - genetics | Microvessels - ultrastructure | Cytokines - metabolism | Mice, Inbred C57BL | Microvessels - drug effects | Pregnancy Proteins - immunology | Antibodies - pharmacology | Proteins - genetics | Neoplasm Metastasis - genetics | Hypoxia - genetics | Lung Neoplasms - immunology | Animals | Proteins - metabolism | Endothelial Cells - cytology | Neoplasm Metastasis - pathology | Macrophages - drug effects | Neovascularization, Pathologic - genetics | Cell Proliferation - drug effects | Proteins - pharmacology | Neoplasms - pathology | Endothelial Cells - drug effects | Index Medicus
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7. Full Text Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation
by Finch, Amy P M and Finch, Amy P. M and Lubinski, Jan and Lubinski, Jan and Møller, Pål and Møller, Pål and Singer, Christian F and Singer, Christian F and Karlan, Beth and Karlan, Beth and Senter, Leigha and Senter, Leigha and Rosen, Barry and Rosen, Barry and Maehle, Lovise and Maehle, Lovise and Ghadirian, Parviz and Ghadirian, Parviz and Cybulski, Cezary and Cybulski, Cezary and Huzarski, Tomasz and Huzarski, Tomasz and Eisen, Andrea and Eisen, Andrea and Foulkes, William D and Foulkes, William D and Kim-Sing, Charmaine and Kim-Sing, Charmaine and Ainsworth, Peter and Ainsworth, Peter and Tung, Nadine and Tung, Nadine and Lynch, Henry T and Lynch, Henry T and Neuhausen, Susan and Neuhausen, Susan and Metcalfe, Kelly A and Metcalfe, Kelly A and Thompson, Islay and Thompson, Islay and Murphy, Joan and Murphy, Joan and Sun, Ping and Sun, Ping and Narod, Steven A and Narod, Steven A
Journal of clinical oncology, ISSN 0732-183X, 2014, Volume 32, Issue 15, pp. 1547 - 1553
Life Sciences & Biomedicine | Oncology | Science & Technology | Ovariectomy - adverse effects | Age Factors | Humans | Middle Aged | Ovarian Neoplasms - pathology | Ovarian Neoplasms - mortality | North America | Incidence | Ovarian Neoplasms - genetics | Time Factors | Fallopian Tube Neoplasms - genetics | Aged, 80 and over | Adult | Female | Registries | Surveys and Questionnaires | Odds Ratio | Peritoneal Neoplasms - pathology | Fallopian Tube Neoplasms - prevention & control | Genetic Predisposition to Disease | Ovarian Neoplasms - prevention & control | Risk Assessment | Europe | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Fallopian Tube Neoplasms - pathology | Treatment Outcome | Peritoneal Neoplasms - prevention & control | Peritoneal Neoplasms - mortality | BRCA1 Protein - genetics | Ovariectomy - mortality | Phenotype | Fallopian Tube Neoplasms - mortality | Peritoneal Neoplasms - genetics | Aged | Mutation | BRCA2 Protein - genetics | Index Medicus | Gync21 | Bios4 | Bc3 | ORIGINAL REPORTS | Gync15
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8. Full Text Distant metastasis occurs late during the genetic evolution of pancreatic cancer
by Bozic, Ivana and Leary, Rebecca and Fu, Baojin and Vogelstein, Bert and Hruban, Ralph H and Iacobuzio-Donahue, Christine A and Antal, Tibor and Kinzler, Kenneth W and Jones, Siân and Kamiyama, Mihoko and Nowak, Martin A and Yachida, Shinichi and Eshleman, James R and Velculescu, Victor E
Nature (London), ISSN 0028-0836, 10/2010, Volume 467, Issue 7319, pp. 1114 - 1117
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Biological and medical sciences | Medical sciences | Liver. Biliary tract. Portal circulation. Exocrine pancreas | Tumors | Adenocarcinoma - pathology | Humans | Lung Neoplasms - secondary | Time Factors | Autopsy | DNA Mutational Analysis | Adenocarcinoma - genetics | Liver Neoplasms - secondary | Cell Lineage - genetics | Peritoneal Neoplasms - secondary | Lung Neoplasms - genetics | Liver Neoplasms - genetics | Early Detection of Cancer | Pancreatic Neoplasms - pathology | Pancreas - pathology | Pancreatic Neoplasms - genetics | Pancreas - metabolism | Mutation - genetics | Clone Cells - metabolism | Disease Progression | Neoplasm Metastasis - genetics | Clone Cells - pathology | Models, Biological | Neoplasm Metastasis - pathology | Peritoneal Neoplasms - genetics | Evolution, Molecular | Genetic aspects | Metastasis | Research | Pancreatic cancer | Mutation | Pancreas | Cancer | Index Medicus
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9. Full Text Relationship between the Expression of the Extracellular Matrix Genes SPARC, SPP1, FN1, ITGA5 and ITGAV and Clinicopathological Parameters of Tumor Progression and Colorectal Cancer Dissemination
by Viana, Luciano de Souza and Affonso Jr, Renato José and Silva, Sandra Regina Morini and Denadai, Marcos Vinicius Araujo and Matos, Delcio and Salinas de Souza, Carolina and Waisberg, Jaques
Oncology, ISSN 0030-2414, 12/2012, Volume 84, Issue 2, pp. 81 - 91
Clinical Translational Research | Integrin | Colorectal carcinoma | Osteonectin | Biomarkers | Osteopontin | Extracellular matrix | Carcinogenesis | Fibronectin | Life Sciences & Biomedicine | Oncology | Science & Technology | Adenocarcinoma - pathology | Follow-Up Studies | Colorectal Neoplasms - genetics | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Immunoenzyme Techniques | Ovarian Neoplasms - genetics | Young Adult | Ovarian Neoplasms - secondary | Adenocarcinoma - metabolism | Aged, 80 and over | Biomarkers, Tumor - metabolism | Ovarian Neoplasms - metabolism | Liver Neoplasms - secondary | Real-Time Polymerase Chain Reaction | Integrin alphaV - metabolism | Tumor Suppressor Proteins - metabolism | Liver Neoplasms - genetics | Lymphatic Metastasis | Reverse Transcriptase Polymerase Chain Reaction | Peritoneal Neoplasms - metabolism | Liver Neoplasms - metabolism | Biomarkers, Tumor - genetics | Integrin alpha5 - genetics | Osteopontin - genetics | Prognosis | Tissue Array Analysis | Osteopontin - metabolism | Lung Neoplasms - secondary | Tumor Suppressor Proteins - genetics | Adult | Female | Adenocarcinoma - genetics | Integrin alphaV - genetics | Colorectal Neoplasms - metabolism | Peritoneal Neoplasms - secondary | Lung Neoplasms - genetics | Neoplasm Invasiveness | RNA, Messenger - genetics | Fibronectins - metabolism | Peritoneal Neoplasms - genetics | Integrin alpha5 - metabolism | Aged | Fibronectins - genetics | Colorectal Neoplasms - pathology | Neoplasm Staging | Cellular biology | Gene expression | Colorectal cancer | Tumors | Index Medicus
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