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JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 07/2004, Volume 166, Issue 1, pp. 97 - 109
Endorepellin, the COOH-terminal domain of the heparan sulfate proteoglycan perlecan, inhibits several aspects of angiogenesis. We provide evidence for a novel... 
RHOA ACTIVITY | perlecan proteoglycan | ACTIVATED PROTEIN-KINASE | angiogenesis | endothelial cell | LG module | collagen | P38 MAPK | CELL BIOLOGY | CYCLIC-AMP | PERLECAN | STRUCTURAL BASIS | GROWTH-FACTOR | MEDIATED INHIBITION | UP-REGULATION
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 7/2004, Volume 166, Issue 1, pp. 97 - 109
Endorepellin, the COOH-terminal domain of the heparan sulfate proteoglycan perlecan, inhibits several aspects of angiogenesis. We provide evidence for a novel... 
Morphogenesis | Angiogenesis | Collagens | Actins | Stress fibers | Antibodies | Focal adhesions | Endothelial cells | Cells | Integrins | Endothelial cell | Perlecan proteoglycan | Collagen | LG module | perlecan proteoglycan; angiogenesis; endothelial cell; collagen; LG module
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 09/2018, Volume 9, pp. 974 - 974
Journal Article
FEBS JOURNAL, ISSN 1742-464X, 05/2013, Volume 280, Issue 10, pp. 2271 - 2284
Endorepellin, a processed fragment of perlecan protein core, possesses anti-angiogenic activity by antagonizing endothelial cells. Endorepellin contains three... 
angiogenesis | BIOCHEMISTRY & MOLECULAR BIOLOGY | PERLECAN PROTEIN CORE | BASEMENT-MEMBRANE PROTEOGLYCANS | VEGFA | VEGF receptor 2 | CANCER GROWTH | endorepellin | CASPASE-3 ACTIVATION | ANGIOSTATIC MODULE | IN-VIVO | perlecan | HEPARAN-SULFATE | MEDIATED INHIBITION | ALPHABETA INTEGRINS | ALPHA-2-BETA-1 INTEGRIN
Journal Article
Acta biomaterialia, ISSN 1742-7061, 07/2019
Growth factor gradients orchestrate many biological processes including organogenesis, wound healing, cancer invasion, and metastasis. Heparin-binding growth... 
Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, pp. e0119247 - e0119247
Journal Article
Glycobiology, ISSN 0959-6658, 1/2010, Volume 20, Issue 1, pp. 33 - 40
Journal Article
Journal Article
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, ISSN 0148-0731, 08/2019, Volume 141, Issue 8, p. 81002
During chondrogenesis, tissue organization changes dramatically. We previously showed that the compressive moduli of chondrocytes increase concomitantly with... 
PERLECAN | CONTACT | COLLAGEN | BIOPHYSICS | CHONDROCYTES | MICROENVIRONMENT | PERICELLULAR MATRIX | ARTICULAR-CARTILAGE | ENGINEERING, BIOMEDICAL | POISSONS RATIO | CELL | DEFORMATION
Journal Article
Journal Article
Journal of Refractive Surgery, ISSN 1081-597X, 05/2017, Volume 33, Issue 5, pp. 337 - 346
PURPOSE: To study regeneration of the normal ultrastructure of the epithelial basement membrane (EBM) in rabbit corneas that had -9.00 D photorefractive... 
SURGERY | PERLECAN | COLLAGEN | RADIAL KERATOTOMY | INJURY | COMPONENTS | OPHTHALMOLOGY | STROMAL CELLS | RABBIT CORNEAS | MICROSCOPY | MYOFIBROBLAST GENERATION | EXPRESSION
Journal Article
Developmental Biology, ISSN 0012-1606, 2003, Volume 253, Issue 2, pp. 247 - 257
Mutations in the Drosophila trol gene cause cell cycle arrest of neuroblasts in the larval brain. Here, we show that trol encodes the Drosophila homolog of... 
Stem cell proliferation | Hedgehog | FGF | trol | Drosophila | Perlecan
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 52, pp. 43543 - 43556
Endorepellin, the angiostatic C-terminal domain of the heparan sulfate proteoglycan perlecan, inhibits angiogenesis by simultaneously binding to the alpha 2... 
CANCER GROWTH | COLON CARCINOMA-CELLS | DOMAIN-III | ANGIOSTATIC ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PERLECAN PROTEIN CORE | VEGF RECEPTOR-2 | HEPARAN-SULFATE PROTEOGLYCAN | BASEMENT-MEMBRANE PROTEOGLYCANS | TUMOR-GROWTH | ALPHA-2-BETA-1 INTEGRIN | Protein Kinase C - genetics | MAP Kinase Signaling System - physiology | Human Umbilical Vein Endothelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Active Transport, Cell Nucleus - physiology | Humans | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Proto-Oncogene Proteins c-akt - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Cell Nucleus - metabolism | MAP Kinase Kinase 4 - metabolism | TOR Serine-Threonine Kinases - genetics | Heparan Sulfate Proteoglycans - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Protein Kinase C - metabolism | Swine | Human Umbilical Vein Endothelial Cells - cytology | Proto-Oncogene Proteins c-akt - metabolism | Peptide Fragments - genetics | Protein-Serine-Threonine Kinases - metabolism | Peptide Fragments - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | NFATC Transcription Factors - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Phosphatidylinositol 3-Kinases - genetics | Neovascularization, Physiologic - physiology | Transcription, Genetic - physiology | Animals | Cell Nucleus - genetics | Heparan Sulfate Proteoglycans - metabolism | MAP Kinase Kinase 4 - genetics | NFATC Transcription Factors - genetics | Index Medicus | Proteoglycan | Angiogenesis | Vascular Endothelial Growth Factor (VEGF) | AP1 | VEGF Receptor 2 | Vascular Biology | Calcineurin | Perlecan | Glycobiology and Extracellular Matrices | Endothelial Cell | NFAT1
Journal Article