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Nature medicine, ISSN 1546-170X, 2016, Volume 22, Issue 3, pp. 312 - 318
Uncoupling protein 1 (UCP1) is highly expressed in brown adipose tissue, where it generates heat by uncoupling electron transport from ATP production. UCP1 is... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | WHITE | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADULT HUMANS | BROWN ADIPOSE-TISSUE | IDENTIFICATION | CELL BIOLOGY | OBESITY | GENE | INFLAMMATION | EXPRESSION | Enkephalins - metabolism | Humans | Middle Aged | Ion Channels - genetics | Male | RNA, Messenger - metabolism | Enkephalins - genetics | Mitochondrial Proteins - metabolism | Diet, High-Fat | Iodide Peroxidase - metabolism | Adipocytes, Brown - transplantation | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Oxygen Consumption | Apoptosis Regulatory Proteins - metabolism | Protein Precursors - metabolism | Mice | Iodide Peroxidase - genetics | Blood Glucose - metabolism | Integrin beta1 - genetics | Adipocytes, White - metabolism | Glucose Intolerance - metabolism | Proprotein Convertase 1 - genetics | Adipocytes, Brown - metabolism | Homeostasis | Mitochondrial Proteins - genetics | DNA-Binding Proteins - metabolism | Polymerase Chain Reaction | Apoptosis Regulatory Proteins - genetics | Adult | Female | Capillaries | Glucose Tolerance Test | Protein Precursors - genetics | Proprotein Convertase 1 - metabolism | Cell Transplantation | Adipocytes, White - transplantation | DNA-Binding Proteins - genetics | Obesity - metabolism | Integrin beta1 - metabolism | Interleukin-33 - genetics | Animals | Ion Channels - metabolism | Receptor, Platelet-Derived Growth Factor alpha - genetics | Adipocytes - metabolism | Fluorescent Antibody Technique | Interleukin-33 - metabolism | Adipocytes - transplantation | Aged | Glucose Clamp Technique | Uncoupling Protein 1 | Neovascularization, Physiologic | Adipose tissues | Physiological aspects | Genetic aspects | Research | cytokine | human adipocyte | glucose | progenitors | adipokine | capillary | adrenergic | thermogenic adipose tissue | implant
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 11/2016, Volume 53, Issue 9, pp. 6459 - 6475
...Oxidative Stress, Disrupted Energy Metabolism, and Altered Signaling Pathways in Glutaryl-CoA Dehydrogenase Knockout Mice: Potential Implications of Quinolinic... 
Signaling pathways | Neurology | Neurosciences | Energy metabolism | Biomedicine | Glutaric acidemia | Redox homeostasis | Neurobiology | Inflammatory response | Quinolinic acid | Cell Biology | PLASMA-MEMBRANES | 3-HYDROXYGLUTARIC ACID | NMDA RECEPTORS | NITRIC-OXIDE SYNTHASE | FACTOR-KAPPA-B | GLUTAMATE UPTAKE | NEUROSCIENCES | CEREBRAL-CORTEX | PRIMARY NEURONAL CULTURES | ANTIOXIDANT RESPONSE ELEMENT | CREATINE-KINASE | Brain Diseases, Metabolic - pathology | Glutaryl-CoA Dehydrogenase - metabolism | Glutathione - metabolism | Antioxidants - metabolism | Fluoresceins - metabolism | Nitrites - metabolism | NF-kappa B - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Electron Transport Complex IV - metabolism | Amino Acid Metabolism, Inborn Errors - metabolism | Sulfhydryl Compounds - metabolism | Neostriatum - drug effects | Lipid Peroxidation - drug effects | Neostriatum - metabolism | Quinolinic Acid - administration & dosage | Quinolinic Acid - toxicity | Amino Acid Metabolism, Inborn Errors - pathology | Brain Diseases, Metabolic - enzymology | Proto-Oncogene Proteins c-akt - metabolism | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | Glutathione Peroxidase - metabolism | Neostriatum - pathology | Oxidation-Reduction | Brain Diseases, Metabolic - metabolism | Mice, Knockout | Nitrates - metabolism | Animals | Lactates - metabolism | Diet | Signal Transduction - drug effects | Models, Biological | NF-E2-Related Factor 2 - metabolism | Oxidative Stress - drug effects | Amino Acid Metabolism, Inborn Errors - enzymology | Energy Metabolism - drug effects | Glutaryl-CoA Dehydrogenase - deficiency | Antioxidants | Lysine | Creatine kinase | Glutathione transferase | Physiological aspects | Superoxide | Inflammation | Creatine | Homeostasis | Signal transduction | Oxidative stress | Bioenergetics | Index Medicus
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 3, p. e33210
Brassinosteroids (BRs) and polyamines (PAs) are well-established growth regulators playing key roles in stress management among plants. In the present study,... 
OXIDATIVE STRESS | RESPONSIVE 2-COMPONENT SYSTEM | TOLERANCE | MULTIDISCIPLINARY SCIENCES | LIGHT | DROUGHT | TOXICITY | ABSCISIC-ACID | SPERMIDINE | CELL-DEATH | WATER | Trace Elements - metabolism | Glutathione Reductase - metabolism | Antioxidants - metabolism | NADPH Oxidases - metabolism | Spermidine - metabolism | Seedlings - growth & development | Brassinosteroids - metabolism | Chromium - toxicity | Raphanus - genetics | Abscisic Acid - metabolism | Plant Proteins - metabolism | Stress, Physiological - drug effects | Raphanus - metabolism | Superoxide Dismutase - metabolism | Brassinosteroids - pharmacology | Indoleacetic Acids - metabolism | Seedlings - drug effects | Chromium - metabolism | Enzyme Activation - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Photosystem II Protein Complex - metabolism | Polyamines - metabolism | Catalase - metabolism | Plant Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Polyamines - pharmacology | Raphanus - drug effects | Spermidine - pharmacology | Plant Growth Regulators - metabolism | Plant Growth Regulators - pharmacology | Peroxidase - metabolism | Seedlings - metabolism | Trace Elements - toxicity | Antioxidants | Enzymes | Physiological aspects | Superoxide | Photosynthesis | Polyamines | Metallothionein | Steroids | Oxidative stress | Regulators | Reactive oxygen species | Hydrogen peroxide | Ascorbic acid | Seeds | Horticulture | Genomics | Proline | Superoxide dismutase | Physiological responses | Catalase | Glutathione reductase | Betaine | Pigments | Abscisic acid | Physiology | Peroxidase | Glycine betaine | Plant sciences | Sugars | Glutathione | Soil contamination | Plants (botany) | Abiotic stress | Growth regulators | Brassinosteroids | Data processing | Phytochelatins | Metabolism | Photosynthetic pigments | Gene expression | Malondialdehyde | Seedlings | Salinity | Studies | Mitigation | Environmental science | Plant growth | Phenols | Chromium | Methods
Journal Article
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 05/2007, Volume 34, Issue 5, pp. 425 - 431
SUMMARY • It is known that stress causes disruption of homeostasis and an imbalanced anti-oxidant status in several organs. The aim of the present study was to... 
immobilization-cold stress | rat | glutathione | protein oxidation | cold stress | anti-oxidant enzymes | lipid peroxidation | immobilization stress | anti‐oxidant enzymes | immobilization–cold stress | Cold stress | Protein oxidation | Rat | Anti-oxidant enzymes | Immobilization-cold stress | Lipid peroxidation | Immobilization stress | Glutathione | CATALASE | ENZYME-ACTIVITIES | DEFENSE | PHYSIOLOGY | GLUCOCORTICOIDS | GLUTATHIONE-PEROXIDASE | BODY-WEIGHT | METABOLISM | AGE-RELATED-CHANGES | PHARMACOLOGY & PHARMACY | BRAIN | EXPOSURE | Protein Carbonylation | Rats, Wistar | Glutathione - metabolism | Zinc - metabolism | Antioxidants - metabolism | Male | Stress, Psychological - psychology | Immobilization - psychology | Kidney - metabolism | Myocardium - metabolism | Copper - metabolism | Corticosterone - blood | Weight Gain | Superoxide Dismutase - metabolism | Glutathione Peroxidase - metabolism | Cold Temperature | Liver - metabolism | Rats | Thiobarbituric Acid Reactive Substances - metabolism | Kidney - cytology | Liver - chemistry | Lipid Peroxidation - physiology | Myocardium - cytology | Catalase - metabolism | Animals | Selenium - metabolism | Models, Biological | Weight Loss | Kidney - chemistry | Liver - cytology | Liver, cytology | Thiobarbituric Acid Reactive Substances, metabolism | Superoxide Dismutase, metabolism | Zinc, metabolism | Antioxidants, metabolism | Kidney, metabolism | Glutathione, metabolism | Myocardium, metabolism | Immobilization, psychology | Corticosterone, blood | Catalase, metabolism | Selenium, metabolism | Liver, chemistry | Cold | Copper, metabolism | Lipid Peroxidation, physiology | Myocardium, cytology | Kidney, chemistry | Liver, metabolism | Glutathione Peroxidase, metabolism | Stress, Psychological, psychology | Kidney, cytology | Antioxidants | Comparative analysis | Oxidation-reduction reaction
Journal Article
Amino acids, ISSN 1438-2199, 2016, Volume 49, Issue 1, pp. 129 - 138
.... Oxidative stress is involved in the pathophysiology of many inborn errors of metabolism. However, little is known about the role of oxidative damage in hepatic and renal changes in hypermethioninemia... 
Life Sciences | Biochemistry, general | Oxidative stress | Analytical Chemistry | Life Sciences, general | Methionine sulfoxide | Biochemical Engineering | Proteomics | Neurobiology | Methionine | Delta aminolevulinic dehydratase | LIPID-PEROXIDATION | ANTIOXIDANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DELTA-AMINOLEVULINATE DEHYDRATASE | DAMAGE | HYPERMETHIONINEMIA | METABOLISM | FAT | ADENOSYLTRANSFERASE I/III DEFICIENCY | PROTEINS | RESIDUES | Glycine N-Methyltransferase - metabolism | Liver - pathology | Reactive Oxygen Species - metabolism | Kidney - pathology | Rats, Wistar | Glycine N-Methyltransferase - deficiency | Male | Methionine - pharmacology | Porphobilinogen Synthase - metabolism | Amino Acid Metabolism, Inborn Errors - metabolism | Kidney - metabolism | Sulfhydryl Compounds - metabolism | Liver - drug effects | Methionine - analogs & derivatives | Injections, Subcutaneous | Female | Urea - metabolism | Amino Acid Metabolism, Inborn Errors - pathology | Superoxide Dismutase - metabolism | Glutathione Peroxidase - metabolism | Amino Acid Metabolism, Inborn Errors - chemically induced | Kidney - drug effects | Methionine - metabolism | Liver - metabolism | Rats | Thiobarbituric Acid Reactive Substances - metabolism | Cholesterol - metabolism | Enzyme Activation - drug effects | Triglycerides - metabolism | Catalase - metabolism | Animals | Glucose - metabolism | Oxidative Stress - drug effects | Lipid Peroxidation | Enzymes | Urea | Liver | Physiological aspects | Amino acids | Triglycerides | Superoxide | Index Medicus
Journal Article
The FASEB Journal, ISSN 0892-6638, 11/2005, Volume 19, Issue 13, pp. 1890 - 1892
ABSTRACTWe investigated a possible beneficial role for bilirubin, one of the products of heme degradation by the cytoprotective enzyme heme oxygenase‐1 in... 
nitric oxide | oxygen free radicals | OXIDATIVE STRESS | SUPEROXIDE | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCTION | BILIVERDIN | CELL BIOLOGY | SYNTHASE EXPRESSION | ANTIOXIDANT | IN-VIVO | BIOLOGY | HEME OXYGENASE-1 | SERUM BILIRUBIN | Nitric Oxide Synthase Type II - biosynthesis | Bilirubin - metabolism | Antioxidants - metabolism | Kidney - enzymology | Malondialdehyde - chemistry | NADPH Oxidases - metabolism | Male | Aorta - metabolism | Kidney - metabolism | Time Factors | Myocardium - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-6 - metabolism | Glutathione Peroxidase - metabolism | Free Radicals | Down-Regulation | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Rats | Rats, Sprague-Dawley | Blotting, Western | Nitrates - metabolism | Macrophages - metabolism | Rats, Gunn | Models, Biological | Lipopolysaccharides - chemistry | Mice | Nitric Oxide Synthase - metabolism | Blood Pressure | Jaundice - pathology | Tumor Necrosis Factor-alpha - metabolism | Nitric Oxide Synthase Type II - chemistry | Nitrites - metabolism | Shock, Septic - prevention & control | Oxygen - metabolism | Shock, Septic - metabolism | Heme - chemistry | Escherichia coli - metabolism | Shock, Septic - drug therapy | Interleukin-10 - metabolism | Aorta - enzymology | Superoxide Dismutase - metabolism | Cell Line | Bilirubin - chemistry | Models, Statistical | Homozygote | Myocardium - enzymology | Animals | Nitric Oxide - metabolism
Journal Article