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Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 4/2011, Volume 108, Issue 16, pp. 6603 - 6608
Journal Article
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2017, Volume 152, Issue 1, pp. 243 - 256
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 2012, Volume 287, Issue 3, pp. 1847 - 1860
.... Moreover, regulation of energy metabolism and immunity are highly integrated. We hypothesized that energy-sensitive coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1 alpha... 
necrosis-factor-alpha | skeletal-muscle | metabolic syndrome | nuclear receptors | hepatic gluconeogenesis | insulin-resistance | caloric restriction | diabetes-mellitus | endoplasmic-reticulum stress | human obesity | DIABETES-MELLITUS | SKELETAL-MUSCLE | HEPATIC GLUCONEOGENESIS | METABOLIC SYNDROME | INSULIN-RESISTANCE | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CALORIC RESTRICTION | HUMAN OBESITY | NECROSIS-FACTOR-ALPHA | ENDOPLASMIC-RETICULUM STRESS | Enzyme Activators - pharmacology | RNA-Binding Proteins - genetics | AMP-Activated Protein Kinases - metabolism | Liver - pathology | Receptors, Interleukin-15 - biosynthesis | Haptoglobins - biosynthesis | Caloric Restriction | Haptoglobins - genetics | Hepatocytes - pathology | Interleukin 1 Receptor Antagonist Protein - genetics | Male | Hepatocytes - metabolism | Obesity - genetics | Gene Knockdown Techniques | Receptors, Interleukin-15 - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Inflammation Mediators - metabolism | Trans-Activators - genetics | Mice, Inbred DBA | Fasting - metabolism | Interleukin 1 Receptor Antagonist Protein - biosynthesis | C-Reactive Protein - biosynthesis | Physical Conditioning, Animal | Gene Expression Regulation - genetics | Liver - metabolism | Metformin - pharmacology | Cells, Cultured | Rats | PPAR alpha - genetics | C-Reactive Protein - genetics | Transcription Factors - genetics | Hypoglycemic Agents - pharmacology | Obesity - metabolism | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Animals | Energy Metabolism | Insulin Resistance - genetics | Obesity - therapy | Trans-Activators - metabolism | Mice | PPAR alpha - metabolism | AMP-Activated Protein Kinases - genetics | RNA-Binding Proteins - metabolism | IL15Rα | IL1Rn | Coactivator Transcription | Liver | Inflammation | Cellular Immune Response | Diabetes | Tweak | Metformin | Metabolism | Nuclear Receptors
Journal Article
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2013, Volume 288, Issue 4, pp. 2246 - 2260
.... The beneficial effects of exercise are mediated in large part by peroxisome proliferator-activated receptor gamma coactivator (PGC... 
P65 SUBUNIT | GENE | INSULIN-RESISTANCE | PGC-1-ALPHA | INFLAMMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | AORTIC SMOOTH-MUSCLE | IKK-BETA | OXIDATIVE-METABOLISM | EXPRESSION | EXERCISE | Transcription Regulation | Exercise | Coactivator Transcription | NF-κB Transcription Factor | PGC-1β | Inflammation | Muscle | PGC-1α | Cell Biology
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 01/2015, Volume 290, Issue 2, pp. 950 - 959
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2013, Volume 34, Issue 6, pp. 1581 - 1588
...). Nicotinamide riboside (NR) is a NAD+ precursor, it promotes peroxisome proliferator-activated receptor-γ coactivator 1 (PGC)-1α... 
Neurology | Internal Medicine | Mitochondrial metabolism | Long-term potentiation | Synaptic plasticity | β-secretase (BACE1) | Nicotinamide riboside | Alzheimer's disease | Promotes peroxisome proliferator-activated receptor (PPAR)-γ coactivator 1 (PGC)-1α | Ubiquitin–proteasome system | Ubiquitin-proteasome system | OXIDATIVE STRESS | SYNAPTIC FUNCTION | DEMENTIA | MECHANISM | PGC-1-ALPHA | Promotes peroxisome proliferator-activated receptor (PPAR)-gamma coactivator 1 (PGC)-1 alpha | SIRT1 | NEUROSCIENCES | PERMEABILITY TRANSITION | GERIATRICS & GERONTOLOGY | beta-secretase (BACE1) | DISEASE | NAD(+) | TRANSGENIC MICE | Niacinamide - analogs & derivatives | Cognition Disorders - metabolism | Mitochondria - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Up-Regulation - physiology | Organ Culture Techniques | Disease Models, Animal | Aspartic Acid Endopeptidases - antagonists & inhibitors | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Alzheimer Disease - drug therapy | Niacinamide - therapeutic use | Mice, Transgenic | Transcription Factors - biosynthesis | Cognition Disorders - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Cognition Disorders - drug therapy | Up-Regulation - drug effects | Amyloid Precursor Protein Secretases - metabolism | Animals | Aspartic Acid Endopeptidases - metabolism | Alzheimer Disease - metabolism | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Niacinamide - pharmacology | Alzheimer Disease - genetics | Index Medicus | Alzheimer’s disease | Promotes peroxisome proliferator-activated | receptor (PPAR)-γ coactivator 1 (PGC)-1α
Journal Article
Kidney international, ISSN 0085-2538, 10/2012, Volume 82, Issue 7, pp. 771 - 789
... peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α), affects podocyte damage... 
mitochondrial dysfunction | podocytes | SIRT1 | aldosterone | PGC-1a | OXIDATIVE STRESS | PGC-1 alpha | INDUCED APOPTOSIS | PGC-1-ALPHA | TRANSCRIPTIONAL COACTIVATOR | CELL APOPTOSIS | METABOLIC REGULATOR | UROLOGY & NEPHROLOGY | RAT PODOCYTES | FOCAL SEGMENTAL GLOMERULOSCLEROSIS | CALORIE RESTRICTION | Sirtuin 1 - metabolism | Apoptosis - drug effects | Receptors, Mineralocorticoid - metabolism | Podocytes - virology | Respiratory Syncytial Virus Infections - metabolism | Stilbenes - pharmacology | Aldosterone | Sirtuin 1 - genetics | Kidney Diseases - genetics | Receptors, Mineralocorticoid - drug effects | Transfection | RNA Interference | Time Factors | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Kidney Diseases - chemically induced | Mineralocorticoid Receptor Antagonists - pharmacology | Trans-Activators - genetics | Respiratory Syncytial Virus Infections - virology | Genes, Reporter | Cytoprotection | Disease Models, Animal | Kidney Diseases - metabolism | Cell Line | Promoter Regions, Genetic | Podocytes - metabolism | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Mice, Inbred C57BL | Gene Expression Regulation | Respiratory Syncytial Virus Infections - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Podocytes - pathology | Animals | Podocytes - drug effects | Mitochondria - virology | Trans-Activators - metabolism | Mice | Transcription Factors | Enzyme Activation | Respiratory Syncytial Viruses - pathogenicity
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 06/2006, Volume 55, Issue 6, pp. 1783 - 1791
...–Activated Receptor-γ Coactivator-1α, Estrogen-Related Receptor-α, and Mitofusin 2 Francesc X... 
COX-II, cytochrome c oxidase subunit-II | Mfn2, mitofusin 2 | PGC, peroxisome proliferator-activated receptor-γ coactivator | MEF2, myocyte enhancer factor-2 | Errα, estrogen-related receptor-α | 2A GENE | HEPATIC GLUCONEOGENESIS | BIOGENESIS | ERR-ALPHA | PGC-1-ALPHA | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | PGC-1 | TRANSCRIPTIONAL COACTIVATOR | ENERGY-METABOLISM | HUMAN SKELETAL-MUSCLE | GTP Phosphohydrolases | Gene Expression - drug effects | Rats, Wistar | Humans | Mitochondria, Muscle - metabolism | Male | Muscle, Skeletal - metabolism | Mitochondrial Proteins - genetics | Muscle, Skeletal - cytology | RNA, Messenger - metabolism | Heat-Shock Proteins - genetics | Transfection | Chromatin Immunoprecipitation | Mitochondrial Proteins - metabolism | Muscle, Skeletal - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Dioxoles - pharmacology | Estrogen Receptor alpha - metabolism | Electrophoretic Mobility Shift Assay | Membrane Proteins - metabolism | Cold Temperature | Membrane Proteins - genetics | Heat-Shock Proteins - metabolism | RNA, Messenger - genetics | Cells, Cultured | Rats | Signal Transduction - genetics | Transcription Factors - genetics | Blotting, Western | Transcription Factors - metabolism | Animals | Estrogen Receptor alpha - genetics | Signal Transduction - drug effects | Protein Binding | Signal Transduction - physiology | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Mice | HeLa Cells
Journal Article
PloS one, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64019
Recent studies showed that the activation of the retinoid X receptor, which dimerizes with peroxisome proliferator-activated receptors (PPARs... 
COACTIVATOR 1-ALPHA PGC-1-ALPHA | OXIDATIVE STRESS | AMYLOID-BETA | ALZHEIMERS-DISEASE | NUCLEAR RECEPTORS | MULTIDISCIPLINARY SCIENCES | A-BETA | NEURONS | TRANSCRIPTIONAL COACTIVATOR | DYSFUNCTION | EXPRESSION | Dynamins - metabolism | Reactive Oxygen Species - metabolism | Mitochondrial Dynamics - genetics | Oxidative Stress | Embryo, Mammalian | Neurons - cytology | Mitochondrial Proteins - genetics | Hippocampus - drug effects | PPAR gamma - metabolism | Mitochondria - ultrastructure | Mitochondria - genetics | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Neurons - metabolism | Neurons - drug effects | Thiazolidinediones - pharmacology | PPAR gamma - genetics | Gene Expression Regulation | Dynamins - genetics | Rats | PPAR alpha - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Pyrimidines - pharmacology | Transcription Factors - genetics | Hippocampus - cytology | Rats, Sprague-Dawley | Transcription Factors - metabolism | Hippocampus - metabolism | Animals | Mitochondrial Dynamics - drug effects | PPAR gamma - agonists | PPAR alpha - agonists | PPAR alpha - metabolism | Primary Cell Culture | Brain | Therapy | Oxidative stress | Reactive oxygen species | Disease | Cognitive ability | Disorders | Mitochondrial DNA | Experiments | Neuromodulation | Fission | Proteins | Receptors | Mitochondria | Neurodegeneration | Apolipoprotein E | Dynamics | Rodents | Pretreatment | Alzheimer's disease | Oxygen | Neurodegenerative diseases | Neurons | Transgenic mice | FDA approval | Metabolism | Gene expression | Dynamic tests | Brain research | Dynamin | Peroxisome proliferator-activated receptors | Immunofluorescence | Hippocampus | Cancer | Animal cognition
Journal Article