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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 8, pp. 3143 - 3148
The endocrine hormone fibroblast growth factor 21 (FGF21) is a powerful modulator of glucose and lipid metabolism and a promising drug for type 2 diabetes.... 
Bone resorption | Bone formation | Bone marrow | Bones | Osteoclasts | Fibroblast growth factors | Gene expression regulation | Adipocytes | Type 2 diabetes mellitus | Osteoblasts | Osteoblast | Adipocyte | Nuclear receptor | Bone metabolism | Thiazolidinediones | thiazolidinediones | FIBROBLAST-GROWTH-FACTOR-21 | MULTIDISCIPLINARY SCIENCES | ALPHA | osteoblast | ADIPOGENESIS | INSULIN SENSITIVITY | OSTEOCLAST | bone metabolism | METABOLISM | adipocyte | nuclear receptor | PPAR-GAMMA | MICE | ROSIGLITAZONE | FGF21 | Bone and Bones - pathology | RANK Ligand - metabolism | Adipogenesis - drug effects | Humans | PPAR gamma - metabolism | Bone and Bones - drug effects | Fibroblast Growth Factors - metabolism | Fibroblast Growth Factors - administration & dosage | Bone and Bones - metabolism | Bone Resorption - metabolism | Thiazolidinediones - pharmacology | Bone Marrow - drug effects | Osteoblasts - drug effects | Osteogenesis - drug effects | Drug Resistance - drug effects | Fibroblast Growth Factors - pharmacology | Mice, Knockout | Osteoblasts - pathology | Organ Size - drug effects | Animals | Bone Marrow - pathology | Bone Resorption - pathology | Mice | Osteoprotegerin - metabolism | Osteoblasts - metabolism | Drugs | Fibroblast growth factor | Energy metabolism | Mesenchyme | Diabetes mellitus | Homeostasis | Bone turnover | Hormones | Glucose metabolism | Side effects | Bone mass | Osteoblastogenesis | adipogenesis | Stem cells | rosiglitazone | Lipid metabolism | Peroxisome proliferator-activated receptors | Bone loss | Index Medicus | Biological Sciences
Journal Article
Diabetes, ISSN 0012-1797, 01/2011, Volume 60, Issue 1, pp. 157 - 167
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2010, Volume 285, Issue 10, pp. 7153 - 7164
The recent insight that brown adipocytes and muscle cells share a common origin and in this respect are distinct from white adipocytes has spurred questions... 
SKELETAL-MUSCLE | NONSHIVERING THERMOGENESIS | FAT-CELLS | MITOCHONDRIAL BIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTIONAL CONTROL | UNCOUPLING PROTEIN-1 | GENE-EXPRESSION | ADULT HUMANS | COLD-ACCLIMATION | ADIPOSE-TISSUE | Adipocytes, White - cytology | Coculture Techniques | Ion Channels - genetics | Male | Epididymis - cytology | Mitochondrial Proteins - genetics | PPAR gamma - metabolism | Oxygen Consumption - physiology | Thermogenesis - physiology | Adipocytes, White - drug effects | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Trans-Activators - genetics | Thiazolidinediones - pharmacology | Cell Differentiation - physiology | PPAR gamma - genetics | Biomarkers - metabolism | Adipocytes, Brown - drug effects | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Hypoglycemic Agents - pharmacology | Mice, Knockout | Adipocytes, White - physiology | Voltage-Dependent Anion Channels - genetics | Adipocytes, Brown - physiology | Animals | Ion Channels - metabolism | PPAR gamma - agonists | Trans-Activators - metabolism | Mice | Transcription Factors | Uncoupling Protein 1 | Adipocytes, Brown - cytology | Voltage-Dependent Anion Channels - metabolism | Index Medicus | Adipocyte | Subcellular Organelles | UCP1 | Brown Adipocytes | Microscopic Imaging | PPARγ | Cell Biology | Receptors | Mitochondria | Nuclear | Mouse | Development Differentiation | Rosiglitazone | White Adipocytes
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 35, pp. 21591 - 21602
Journal Article
Kidney International, ISSN 0085-2538, 10/2012, Volume 82, Issue 7, pp. 771 - 789
Glomerular podocytes are highly specialized epithelial cells whose injury in glomerular diseases causes proteinuria. Since mitochondrial dysfunction is an... 
mitochondrial dysfunction | podocytes | SIRT1 | aldosterone | PGC-1a | OXIDATIVE STRESS | PGC-1 alpha | INDUCED APOPTOSIS | PGC-1-ALPHA | TRANSCRIPTIONAL COACTIVATOR | CELL APOPTOSIS | METABOLIC REGULATOR | UROLOGY & NEPHROLOGY | RAT PODOCYTES | FOCAL SEGMENTAL GLOMERULOSCLEROSIS | CALORIE RESTRICTION | Sirtuin 1 - metabolism | Apoptosis - drug effects | Receptors, Mineralocorticoid - metabolism | Podocytes - virology | Respiratory Syncytial Virus Infections - metabolism | Stilbenes - pharmacology | Aldosterone | Sirtuin 1 - genetics | Kidney Diseases - genetics | Receptors, Mineralocorticoid - drug effects | Transfection | RNA Interference | Time Factors | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Kidney Diseases - chemically induced | Mineralocorticoid Receptor Antagonists - pharmacology | Trans-Activators - genetics | Respiratory Syncytial Virus Infections - virology | Genes, Reporter | Cytoprotection | Disease Models, Animal | Kidney Diseases - metabolism | Cell Line | Promoter Regions, Genetic | Podocytes - metabolism | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Mice, Inbred C57BL | Gene Expression Regulation | Respiratory Syncytial Virus Infections - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Podocytes - pathology | Animals | Podocytes - drug effects | Mitochondria - virology | Trans-Activators - metabolism | Mice | Transcription Factors | Enzyme Activation | Respiratory Syncytial Viruses - pathogenicity | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 32, pp. 19544 - 19557
Peroxisome proliferator-activated receptor gamma (PPAR gamma) ligands have been widely used to treat type 2 diabetes mellitus. However, knowledge of PPAR gamma... 
DIABETES-MELLITUS | RETINOIC ACID | GLUCOSE-METABOLISM | FREE FATTY-ACIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | ENDOTHELIAL-CELLS | KINASE | P38 MAPK | COACTIVATOR PGC-1-ALPHA | DEPENDENT MANNER | Sirtuin 1 - metabolism | RNA, Small Interfering - genetics | Luciferases - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | E1A-Associated p300 Protein - genetics | E1A-Associated p300 Protein - metabolism | PPAR gamma - metabolism | Sirtuin 1 - genetics | Luciferases - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Transcription, Genetic | p38 Mitogen-Activated Protein Kinases - metabolism | Thiazolidinediones - pharmacology | Genes, Reporter | PPAR gamma - genetics | Cell Line | Receptor Cross-Talk | Endothelial Cells - metabolism | Gene Expression Regulation | p38 Mitogen-Activated Protein Kinases - genetics | Signal Transduction - genetics | DNA - metabolism | Transcription Factors - genetics | Hypoglycemic Agents - pharmacology | DNA - genetics | Transcription Factors - metabolism | Endothelial Cells - cytology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Protein Binding | Ligands | Receptors, G-Protein-Coupled - genetics | Primary Cell Culture | Endothelial Cells - drug effects | RNA, Small Interfering - metabolism | Index Medicus | peroxisome proliferator-activated receptor (PPAR) | thiazolidinedione | G protein-coupled receptor 40 (GPR40) | Signal Transduction | E1A-binding protein p300 (P300) | sirtuin 1 (SIRT1) | G protein-coupled receptor (GPCR) | peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1a)(PPARGC1A) | peroxisome proliferator-activated receptor gamma (PPARgamma) | p38 MAPK
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2018, Volume 38, Issue 8, pp. 1738 - 1747
OBJECTIVE—Perivascular adipose tissue (PVAT) contributes to vascular homeostasis by producing paracrine factors. Previously, we reported that selective... 
adipose tissue, brown | atherosclerosis | Brown | Adipose tissue | peroxisome proliferator-activated receptors | animals | mice | Index Medicus
Journal Article