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The Journal of Cell Biology, ISSN 0021-9525, 9/2009, Volume 186, Issue 6, pp. 805 - 816
The dynamin-related guanosine triphosphatase Drp1 mediates the division of mitochondria and peroxisomes. To understand the in vivo function of Drp1, complete... 
Cerebellum | Mitochondria | Peroxisomes | Neurons | Antibodies | Cytochromes | Reports | Mice | Giant cells | Embryos | Apoptosis | OUTER-MEMBRANE | APOPTOSIS | DOMINANT OPTIC ATROPHY | FUSION | MITOCHONDRIAL FISSION MACHINERY | SYNAPSE FORMATION | CYTOCHROME-C RELEASE | PROTEIN DLP1 | DIVISION | CELL-DEATH | CELL BIOLOGY | Mitochondria - enzymology | Trophoblasts - ultrastructure | Fibroblasts - enzymology | Giant Cells - enzymology | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Trophoblasts - enzymology | Cerebellum - enzymology | Fibroblasts - ultrastructure | Mitochondria - ultrastructure | Purkinje Cells - enzymology | Cerebellum - embryology | Myocytes, Cardiac - enzymology | Adenosine Triphosphate - metabolism | Ultrasonography | Microtubule-Associated Proteins - deficiency | Purkinje Cells - diagnostic imaging | Mice, Inbred C57BL | Cells, Cultured | Dynamins | Gestational Age | Mice, Knockout | Organogenesis | Animals | GTP Phosphohydrolases - metabolism | GTP Phosphohydrolases - genetics | GTP Phosphohydrolases - deficiency | Peroxisomes - enzymology | Cerebellum - ultrastructure | Mitochondrial Size | Myocytes, Cardiac - ultrastructure | Organelle Shape | Peroxisomes - ultrastructure | Giant Cells - ultrastructure | Physiological aspects | Brain | Embryonic development | Research | Guanosine triphosphatase
Journal Article
Science, ISSN 0036-8075, 08/2018, Volume 361, Issue 6401, pp. CP15 - U70
Our textbook image of organelles has changed. Instead of revealing isolated cellular compartments, the picture now emerging shows organelles as largely... 
DEPENDENT ANION CHANNEL | LATE ENDOSOMES | MECHANISTIC INSIGHTS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | REGULATES CA2+ DYNAMICS | ENDOPLASMIC-RETICULUM | PHOSPHATIDIC-ACID | CRAC CHANNELS | LIPID DROPLETS | MITOCHONDRIAL FISSION | Calcium - metabolism | Vesicular Transport Proteins - metabolism | Humans | Endoplasmic Reticulum - metabolism | Lipid Metabolism | Vesicular Transport Proteins - chemistry | Cell Membrane - ultrastructure | Mitochondria - metabolism | Neurodegenerative Diseases - metabolism | Mitochondria - ultrastructure | Endoplasmic Reticulum - ultrastructure | Endosomes - metabolism | Peroxisomes - metabolism | Animals | Metabolic Networks and Pathways | Endosomes - ultrastructure | Cell Membrane - metabolism | Lipid Droplets - metabolism | Microscopy, Fluorescence | Peroxisomes - ultrastructure | Pictures | Membranes | Ribosomes | Homeostasis | Fluorescence | STIM1 protein | Lipids | Retina | Biology | Cell interactions | Floating structures | Proteins | Paraplegia | Charcot-Marie-Tooth disease | Division | Spastic paraplegia | Communication | Calcium channels | Ion transport | Tubules | Still pictures | Amyotrophic lateral sclerosis | Electron microscopy | Orai1 protein | Organelles | Chemical compounds | Hereditary spastic paraplegia | Microscopy | Microtubules | Fluorophores | Retinal degeneration | Dystrophy | Molecular biology | Endoplasmic reticulum | Cellular structure | Fluorescence microscopy | Myopathy
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0172103
Endurance exercise is a remarkable intervention for the treatment of many diseases. Mitochondria) changes on skeletal muscle are likely important for many of... 
TRANSCRIPTIONAL COACTIVATOR PGC-1-ALPHA | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | MESSENGER-RNA | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | UP-REGULATION | HUMAN SKELETAL-MUSCLE | EXERCISE | ADIPOSE-TISSUE | Microscopy, Electron, Transmission | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics | Protein Carbonylation | Glucose Tolerance Test | Blood Glucose - analysis | Oxidative Stress | Rats, Wistar | Insulin Resistance | Rats | Male | Muscle, Skeletal - metabolism | Mitochondria - metabolism | Insulin - blood | Mitochondria - ultrastructure | Adipose Tissue - metabolism | Animals | Diet, Carbohydrate Loading | Glucose - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism | Citrate (si)-Synthase - metabolism | Swimming | Physical Conditioning, Animal | Superoxide Dismutase - metabolism | Medical research | Mitochondria | Exercise | Cell metabolism | Homeostasis | Medicine, Experimental | Research | Properties | Health aspects | Adipose tissue | Physical training | Physical activity | Weaning | Body weight | Superoxide dismutase | Glucose | Kinases | Alterations | Ultrastructure | Rodents | Animal tissues | Infrared radiation | Working conditions | Endurance | Gastrocnemius muscle | Sugar | Carbonyls | Carbohydrates | Medical treatment | Muscles | Electron microscopy | Insulin | Skeletal muscle | Workload | Glucose tolerance | Intolerance | Transmission electron microscopy | Insulin resistance
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 3/2012, Volume 21, Issue 5, pp. 1124 - 1137
There is substantial evidence that impairment of peroxisome proliferator-activated receptor (PPAR)-γ-coactivator 1α (PGC-1α) levels and activity play an... 
RESPIRATORY-CHAIN | OXIDATIVE STRESS | COACTIVATOR | RECEPTOR-GAMMA | PGC-1-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTANT HUNTINGTIN | GENETICS & HEREDITY | NULL MICE | NEURODEGENERATION | DYSFUNCTION | ADIPOSE-TISSUE | Neurons - pathology | Vacuoles - ultrastructure | Oxidative Stress | Huntington Disease - pathology | Transcriptional Activation | Bezafibrate - pharmacology | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | PPAR gamma - metabolism | Mitochondria - ultrastructure | Gliosis - pathology | Neuroprotective Agents - pharmacology | Muscle Fibers, Skeletal - ultrastructure | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Adipose Tissue, Brown - ultrastructure | Huntington Disease - drug therapy | Neuroprotective Agents - administration & dosage | Corpus Striatum - pathology | Disease Models, Animal | Mice, Transgenic | Survival Rate | Mitochondria - metabolism | Signal Transduction - genetics | Mitochondria - drug effects | Huntington Disease - metabolism | Bezafibrate - administration & dosage | Phenotype | Animals | Diet | Signal Transduction - drug effects | PPAR gamma - agonists | Huntington Disease - genetics | Mitochondria, Muscle - ultrastructure | Trans-Activators - metabolism | Adipose Tissue, Brown - drug effects | Mice | Mitochondria, Muscle - drug effects | Transcription Factors | Neuroprotection | Animal models | Transgenic mice | Muscles | Lipids | Huntington's disease | Atrophy | Diets | Mitochondria | Gliosis | Bezafibrate | Neostriatum | Glycolysis | Peroxisome proliferator-activated receptors | Adipose tissue (brown) | PGC-1 protein
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Journal Article