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Nature Immunology, ISSN 1529-2908, 05/2012, Volume 13, Issue 5, pp. 449 - 456
Intestinal phagocytes transport oral antigens and promote immune tolerance, but their role in innate immune responses remains unclear. Here we found that... 
FLAGELLIN | PATTERN-RECOGNITION | NOD-LIKE RECEPTORS | ACTIVATES CASPASE-1 | MACROPHAGES | INTERLEUKIN-1-BETA | INFLAMMASOME RECEPTORS | INFECTION | NLRP3 INFLAMMASOME | SECRETION | IMMUNOLOGY | Inflammasomes - metabolism | Humans | Receptors, Interleukin-1 - genetics | Salmonella Infections - genetics | Salmonella Infections - immunology | Clonal Anergy | Caspase 1 - metabolism | Monocytes - metabolism | Monocytes - immunology | Intestines - immunology | Host-Pathogen Interactions - immunology | Signal Transduction - immunology | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | Tumor Necrosis Factor-alpha - immunology | Apoptosis Regulatory Proteins - genetics | Pseudomonas - immunology | Toll-Like Receptors - metabolism | Neutrophil Infiltration - immunology | Neutrophils - pathology | Apoptosis Regulatory Proteins - immunology | Flagellin - immunology | Receptors, Interleukin-1 - immunology | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Neutrophils - immunology | Salmonella - genetics | Signal Transduction - genetics | Phagocytes - immunology | Neutrophil Infiltration - genetics | Mice, Knockout | Pseudomonas Infections - immunology | Salmonella - immunology | Animals | Intestines - microbiology | Phagocytes - microbiology | Inflammasomes - immunology | Interleukin-6 - immunology | Interleukin-6 - biosynthesis | Mice | Mice, Inbred BALB C | Tumor Necrosis Factor-alpha - biosynthesis | Calcium-Binding Proteins - genetics
Journal Article
Journal Article
Blood, ISSN 0006-4971, 02/2013, Volume 121, Issue 6, pp. 1008 - 1015
The majority of peripheral serotonin is stored in platelets, which secrete it on activation. Serotonin releases Weibel-Palade bodies (WPBs) and we asked... 
PULMONARY-HYPERTENSION | PERMEABILITY | 5-HYDROXYTRYPTAMINE | ENDOTHELIAL-CELLS | MAST-CELLS | P-SELECTIN | RECEPTOR | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | VON-WILLEBRAND-FACTOR | SELECTIN-DEFICIENT MICE | Blood Platelets - immunology | Endothelium, Vascular - drug effects | Male | Shock, Septic - immunology | Lipopolysaccharides | Serotonin - blood | Inflammation - metabolism | L-Selectin - immunology | Leukocytosis - metabolism | Weibel-Palade Bodies - metabolism | Chemotaxis - immunology | Neutrophils - metabolism | Serotonin - immunology | Serotonin Uptake Inhibitors - immunology | Endothelium, Vascular - immunology | Neutrophil Infiltration - immunology | Fluoxetine - pharmacology | Acute Disease | Neutrophils - drug effects | Leukocytosis - immunology | Chemotaxis - drug effects | Mice, Knockout | Blood Platelets - metabolism | Endothelium, Vascular - metabolism | Mice | Serotonin Uptake Inhibitors - pharmacology | Leukocyte Rolling - drug effects | Weibel-Palade Bodies - immunology | Histamine - immunology | L-Selectin - metabolism | Flow Cytometry | Tryptophan Hydroxylase - deficiency | Blood Platelets - drug effects | Fluoxetine - immunology | Shock, Septic - genetics | Leukocyte Rolling - genetics | Histamine - pharmacology | Shock, Septic - chemically induced | Mice, Inbred C57BL | Kaplan-Meier Estimate | Neutrophils - immunology | Inflammation - immunology | Leukocyte Rolling - immunology | Tryptophan Hydroxylase - genetics | Weibel-Palade Bodies - drug effects | Animals | Serotonin - metabolism | Inflammation - genetics | Leukocytosis - genetics | Phagocytes, Granulocytes, and Myelopoiesis | Platelets and Thrombopoiesis
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2014, Volume 211, Issue 6, pp. 1037 - 1048
Resolution of inflammation is now recognized as a biosynthetically active process involving pro-resolving mediators. Here, we show in zymosan-initiated... 
CIRCUITS | MEDICINE, RESEARCH & EXPERIMENTAL | PROTECTINS | CHEMOTAXIS | INHIBITS LEUKOCYTE MIGRATION | NETRIN-1 | ATHEROSCLEROSIS | MECHANISMS | IMMUNOLOGY | RECEPTORS | HUMAN PHAGOCYTES | PRORESOLVING LIPID MEDIATORS | Netrin-1 | Humans | Lipids - immunology | Monocytes - metabolism | Monocytes - immunology | Nerve Growth Factors - metabolism | Docosahexaenoic Acids - immunology | Inflammation - metabolism | Lipids - chemistry | Tumor Suppressor Proteins - genetics | Inflammation Mediators - metabolism | Chemotaxis - immunology | Neutrophils - metabolism | Macrophages - immunology | Inflammation Mediators - immunology | Recombinant Proteins - metabolism | Zymosan | Tumor Suppressor Proteins - metabolism | Vagus Nerve - metabolism | Mice, Inbred C57BL | Neutrophils - drug effects | Peritonitis - metabolism | Cells, Cultured | Lipoxins - immunology | Neutrophils - immunology | Vagus Nerve - surgery | Inflammation - immunology | Nerve Growth Factors - immunology | Peritonitis - chemically induced | Chemotaxis - drug effects | Peritonitis - immunology | Recombinant Proteins - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Tumor Suppressor Proteins - immunology | Vagotomy | Blotting, Western | Mice, Knockout | Macrophages - metabolism | Animals | Recombinant Proteins - immunology | Nerve Growth Factors - genetics | Vagus Nerve - immunology | Inflammation - genetics | Mice | Lipoxins - metabolism | Microscopy, Fluorescence | Docosahexaenoic Acids - metabolism | Index Medicus | 303
Journal Article
NATURE, ISSN 0028-0836, 02/2013, Volume 494, Issue 7435, pp. 116 - 120
Journal Article
Journal Article
Nature communications, ISSN 2041-1723, 11/2018, Volume 9, Issue 1, pp. 4845 - 13
Circulating monocytes can compete for virtually any tissue macrophage niche and become long-lived replacements that are phenotypically indistinguishable from... 
ADULT MICROGLIA | MOLECULAR SIGNATURES | ORIGIN | DENDRITIC CELLS | MACROPHAGE ONTOGENY | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | MONOCYTES | CENTRAL-NERVOUS-SYSTEM | MYELOID CELLS | REVEALS | CX3C Chemokine Receptor 1 - immunology | Whole-Body Irradiation | Cell Proliferation | Monocytes - cytology | Monocytes - radiation effects | Antigens, Ly - genetics | Lectins, C-Type - immunology | Green Fluorescent Proteins - genetics | Monocytes - immunology | Adoptive Transfer | Microglia - radiation effects | Interferon Type I - immunology | Lectins, C-Type - genetics | DNA Methylation | Microglia - immunology | Monocytes - transplantation | Receptors, Mitogen - immunology | CX3C Chemokine Receptor 1 - genetics | Bone Marrow Cells - immunology | Bacterial Proteins - immunology | Macrophages - radiation effects | Genes, Reporter | Macrophages - immunology | Microglia - cytology | Brain - cytology | Luminescent Proteins - immunology | Signal Transduction | Bone Marrow Cells - cytology | Gene Expression Regulation - immunology | Mice, Transgenic | Brain - radiation effects | Macrophages - cytology | Transplantation Chimera | Cell Lineage - radiation effects | Animals | Green Fluorescent Proteins - immunology | Antigens, Ly - immunology | Interferon Type I - genetics | Antigens, Differentiation - genetics | Mice | Brain - immunology | Phagocytosis | Antigens, Differentiation - immunology | Cell Lineage - immunology | Receptors, Mitogen - genetics | Brain | Transcription | Repopulation | CX3CR1 protein | Macrophages | Gene expression | Embryos | Microglia | Phagocytes | Monocytes | Cell activation | Blood-brain barrier | DNA methylation | Infiltration | Interferon | Methylation | Surface markers | Colonization | Deoxyribonucleic acid--DNA | Cell and Molecular Biology | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cell- och molekylärbiologi | Medicinska och farmaceutiska grundvetenskaper
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2018, Volume 14, Issue 5, p. e1007069
The opportunistic fungal pathogen Candida albicans frequently causes diseases such as oropharyngeal candidiasis (OPC) in immunocompromised individuals.... 
FUNGAL-INFECTION | MICROBIOLOGY | CHRONIC MUCOCUTANEOUS CANDIDIASIS | LANGERHANS CELLS | HYPER-IGE SYNDROME | VIROLOGY | IL-17-PRODUCING T-CELLS | HOST-DEFENSE | STAT1 MUTATIONS | CONVENTIONAL DENDRITIC CELLS | LYMPHOID-CELLS | PARASITOLOGY | TH17 CELLS | Mononuclear Phagocyte System - immunology | Spleen - immunology | Dendritic Cells - immunology | Lectins, C-Type - immunology | Tongue - microbiology | Male | Leukocytes - immunology | Flow Cytometry | Female | Tongue - cytology | Interleukin-1beta - biosynthesis | Cytokines - immunology | Mouth Mucosa - cytology | Mouth Mucosa - microbiology | Tongue - immunology | Specific Pathogen-Free Organisms | Thy-1 Antigens - immunology | Mice, Inbred C57BL | Mouth Mucosa - immunology | Neutrophils - immunology | Spleen - cytology | Interleukin-17 - biosynthesis | Candida albicans - immunology | Interleukin-23 - immunology | Candidiasis, Oral - immunology | Animals | Mannose-Binding Lectins - immunology | Candidiasis, Oral - microbiology | Interleukin-23 - biosynthesis | Interleukin-6 - biosynthesis | Mice | Antigens, Surface - immunology | Candidiasis | Tongue | Mucosal immunity | Fungicides | Cytokines | Dendritic cells | Mucosa | Opportunist infection | Interleukin 23 | Infections | Lymphocytes T | Inflammation | Leukocytes | Macrophages | Immunity | Interleukin 17 | Interleukin 6 | White blood cells | CD90 antigen | Monocytes | Immunology | Lymphocytes | Rodents | Population
Journal Article
Immunity, ISSN 1074-7613, 11/2014, Volume 41, Issue 5, pp. 776 - 788
Journal Article