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Nature (London), ISSN 1476-4687, 05/2011, Volume 474, Issue 7351, pp. 385 - 389
Live vaccines have long been known to trigger far more vigorous immune responses than their killed counterparts(1-6). This has been attributed to the ability... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phagosomes - microbiology | RNA, Messenger - immunology | Inflammasomes - metabolism | Interferon-beta - immunology | Bacterial Vaccines - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Adaptor Proteins, Vesicular Transport - deficiency | Microbial Viability - immunology | Bacteria - immunology | Phagosomes - immunology | Interferon-beta - genetics | RNA, Bacterial - genetics | Macrophages - immunology | Macrophages - microbiology | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Microbial Viability - genetics | Adaptor Proteins, Vesicular Transport - immunology | Macrophages - cytology | Bacteria - genetics | Virulence Factors | Immunity, Innate - immunology | Vaccines, Attenuated - immunology | Vaccines, Inactivated - immunology | Animals | Carrier Proteins - metabolism | Bacterial Vaccines - immunology | Inflammasomes - immunology | Dendritic Cells - microbiology | RNA, Bacterial - immunology | Antibodies, Bacterial - immunology | Bacteria - pathogenicity | Dendritic Cells - cytology | Mice | Phagocytosis | Vaccines, Attenuated - genetics | Proteins | Bacteria | Microbiology | Kinases | Immune system | Index Medicus | toll-like receptors | transcription factors | inflammasome | innate | recognition | phagosome | t-cell responses | activation | regulators | protective immunity
Journal Article
Current opinion in immunology, ISSN 0952-7915, 2011, Volume 23, Issue 5, pp. 564 - 572
Highlights ► Overview of RIG-I mediated signaling to the IFN antiviral response: specificity, complexity and diversity. ► Overview of the recent findings... 
Allergy and Immunology | Life Sciences & Biomedicine | Immunology | Science & Technology | RNA Helicases - metabolism | Humans | NF-kappa B - immunology | Endoplasmic Reticulum - metabolism | NF-kappa B - metabolism | Mitochondria - immunology | Interferon Type I - immunology | Interferon-Induced Helicase, IFIH1 | Signal Transduction - immunology | RNA Viruses - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | DEAD-box RNA Helicases - metabolism | RNA Virus Infections - immunology | Transcription Factors - immunology | Mitochondrial Membranes - immunology | Peroxisomes - immunology | Mitochondria - metabolism | RNA Virus Infections - virology | Immunity, Innate | Peroxisomes - metabolism | Mitochondrial Membranes - metabolism | Transcription Factors - metabolism | Apoptosis - immunology | Endoplasmic Reticulum - immunology | DEAD-box RNA Helicases - immunology | RNA, Viral - immunology | RNA Helicases - immunology | Adaptor Proteins, Signal Transducing - metabolism | Mitochondrial DNA | Interferon | Biological response modifiers | Ligases | Pathogens | RNA viruses | Immune response | Phagosomes | Inflammation | adaptor proteins | Infection | Signal transduction | Mitochondria | NF- Kappa B protein | Peroxisomes | Reviews | Endoplasmic reticulum | Apoptosis | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 6/2011, Volume 108, Issue 24, pp. 9927 - 9932
Cross-presentation of IgG-containing immune complexes (ICs) is an important means by which dendritic cells (DCs) activate CD8⁺ T cells, yet it proceeds by an... 
T lymphocytes | Antigens | Fc receptors | Cross priming | Dendritic cells | Internalization | Phagosomes | Inflammation | Oxidation | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Dextran Sulfate | Membrane Glycoproteins - metabolism | Cytosol - immunology | Dendritic Cells - immunology | Receptors, Fc - metabolism | NADPH Oxidases - metabolism | NADPH Oxidases - immunology | Vacuolar Proton-Translocating ATPases - metabolism | Receptors, IgG - metabolism | Histocompatibility Antigens Class I - metabolism | Vacuolar Proton-Translocating ATPases - immunology | Phagosomes - immunology | Flow Cytometry | Immunoglobulin G - immunology | Colitis - chemically induced | Membrane Glycoproteins - immunology | Colitis - immunology | Dendritic Cells - metabolism | rab GTP-Binding Proteins - metabolism | CD11b Antigen - immunology | Mice, Inbred C57BL | Phagosomes - metabolism | Histocompatibility Antigens Class I - immunology | Mice, Transgenic | Histocompatibility Antigens Class I - genetics | Receptors, IgG - immunology | NADPH Oxidase 2 | Blotting, Western | CD8 Antigens - immunology | Mice, Knockout | CD8 Antigens - metabolism | Animals | Immunoglobulin G - genetics | Receptors, Fc - immunology | Cross-Priming - immunology | rab GTP-Binding Proteins - immunology | Colitis - metabolism | Protein Binding | rab27 GTP-Binding Proteins | Antigens - immunology | Cytosol - metabolism | Receptors, Fc - genetics | Mice | CD11b Antigen - metabolism | Mutation | Hydrogen-Ion Concentration | Immunoglobulin G - metabolism | Index Medicus | Biological Sciences
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 10/2012, Volume 287, Issue 41, pp. 34149 - 34156
Dectin-1 is a pattern recognition receptor that is important for innate immune responses against fungi in humans and mice. Dectin-1 binds to beta-glucans in... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Protein-Tyrosine Kinases - metabolism | Dendritic Cells - immunology | Lectins, C-Type - immunology | NADPH Oxidases - immunology | Intracellular Signaling Peptides and Proteins - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Lectins, C-Type - genetics | Enzyme Activation - immunology | Protein-Tyrosine Kinases - immunology | CD4-Positive T-Lymphocytes - immunology | Lectins, C-Type - metabolism | Phagosomes - immunology | Protein-Tyrosine Kinases - genetics | Bone Marrow Cells - immunology | NADPH Oxidases - genetics | Histocompatibility Antigens Class II - metabolism | beta-Glucans - immunology | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Macrophages - immunology | Cell Line | Bone Marrow Cells - cytology | Antigens, Fungal - metabolism | CD4-Positive T-Lymphocytes - cytology | Phagosomes - metabolism | CD4-Positive T-Lymphocytes - metabolism | Antigens, Fungal - immunology | Macrophages - cytology | Mice, Knockout | Microtubule-Associated Proteins - immunology | beta-Glucans - metabolism | Animals | Histocompatibility Antigens Class II - immunology | Autophagy-Related Protein 5 | Protein Binding | Dendritic Cells - cytology | Mice | Histocompatibility Antigens Class II - genetics | Enzyme Activation - genetics | Antigen Presentation - physiology | Phagosomes - genetics | Index Medicus | Lectin | Dectin-1 | Immunology | Dendritic Cells | Innate Immunity | Macrophages | Phagocytosis
Journal Article
Nature immunology, ISSN 1529-2916, 05/2013, Volume 14, Issue 6, pp. 543 - 553
Journal Article
Nature immunology, ISSN 1529-2908, 02/2016, Volume 17, Issue 2, pp. 196 - 203
Journal Article
The Journal of immunology (1950), ISSN 0022-1767, 06/2011, Volume 186, Issue 11, pp. 6532 - 6542
Journal Article
PloS one, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, pp. e0158629 - e0158629
Porphyromonas gingivalis is a keystone pathogen in the development of chronic periodontitis. Tissue macrophages are amongst the first immune cells to respond... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phagosomes - microbiology | Tumor Necrosis Factor-alpha - metabolism | Interleukin-12 - genetics | Tumor Necrosis Factor-alpha - genetics | Porphyromonas gingivalis - physiology | Host-Pathogen Interactions - immunology | Microbial Viability - immunology | Phagosomes - immunology | Nitric Oxide Synthase Type II - immunology | Time Factors | Gene Expression - immunology | Inflammation Mediators - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Porphyromonas gingivalis - immunology | Macrophages - immunology | Macrophages - microbiology | Cell Line | Macrophages - classification | Macrophage Activation - immunology | Phagocytosis - immunology | Interleukin-12 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Tumor Necrosis Factor-alpha - pharmacology | Animals | Apoptosis - immunology | Nitric Oxide Synthase Type II - genetics | Interferon-gamma - immunology | Interleukin-10 - genetics | Interleukin-12 - immunology | Mice | Macrophage Activation - drug effects | Interleukin-10 - immunology | Interferon-gamma - pharmacology | Nitric Oxide Synthase Type II - metabolism | Anaerobic bacteria | Cytokines | Periodontitis | Analysis | Research | Macrophages | Phagocytosis | Dental schools | Disease | Simpson, James | Inflammatory response | Infections | Experiments | Proteins | Genotype & phenotype | Phagocytes | Interleukin 4 | Cell activation | E coli | Bacteria | Tumor necrosis factor-TNF | Immune system | Pathogens | Phenotypes | Interleukin 12 | Priming | Inflammation | Tumor necrosis factor-α | Gene expression | Nitric-oxide synthase | Cell death | Oral hygiene | γ-Interferon | TNF inhibitors | Ligands | Diabetes | Respiratory burst | Apoptosis | Index Medicus
Journal Article