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Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, ISSN 1198-743X, 12/2017
Deriving suitable dosing regimens for antibiotic combination therapy poses several challenges as the drug interaction can be highly complex, the traditional... 
Simulations | Semi-mechanistic pharmacokinetic–pharmacodynamic modelling | Medical and Health Sciences | Antibiotics | Medicin och hälsovetenskap | Interaction | Drug combinations
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 10/2011, Volume 50, Issue 10, pp. 675 - 686
Background and Objective: Rivaroxaban is an oral, direct Factor Xa inhibitor, which is at an advanced stage of clinical development for prevention and... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Dose-prediction | Rivaroxaban | Pharmacodynamic-modelling | Atrial-fibrillation | Deep-vein-thrombosis | Population- pharmacokinetics | Factor-Xa-inhibitors | Antithrombotics | Pharmacology | Pharmacokinetic-pharmacodynamic-relationships | Pharmacokinetic-modelling | ENOXAPARIN | IN-VITRO | FACTOR-XA INHIBITOR | BAY-59-7939 | MANAGEMENT | VENOUS THROMBOEMBOLISM | METABOLISM | ARTHROPLASTY | PHARMACOLOGY & PHARMACY | PHARMACODYNAMICS | THROMBOPROPHYLAXIS | Body Weight | Age Factors | Anticoagulants - administration & dosage | Factor Xa Inhibitors | Humans | Middle Aged | Venous Thrombosis - blood | Male | Thiophenes - administration & dosage | Morpholines - blood | Thiophenes - blood | Young Adult | Computer Simulation | Aged, 80 and over | Adult | Female | Acute Disease | Stroke - prevention & control | Venous Thrombosis - drug therapy | Administration, Oral | Atrial Fibrillation - drug therapy | Morpholines - administration & dosage | Morpholines - pharmacology | Thiophenes - pharmacology | Anticoagulants - blood | Atrial Fibrillation - blood | Stroke - blood | Thiophenes - pharmacokinetics | Models, Biological | Anticoagulants - pharmacology | Adolescent | Aged | Anticoagulants - pharmacokinetics | Morpholines - pharmacokinetics | Index Medicus
Journal Article
The AAPS Journal, ISSN 1550-7416, 9/2019, Volume 21, Issue 5, pp. 1 - 11
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 2008, Volume 47, Issue 3, pp. 203 - 216
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 10/2011, Volume 50, Issue 10, pp. 627 - 635
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 02/2015, Volume 79, Issue 2, pp. 286 - 297
Journal Article
Malaria Journal, ISSN 1475-2875, 09/2016, Volume 15, Issue 1, pp. 469 - 469
Journal Article
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, ISSN 0924-8579, 01/2015, Volume 45, Issue 1, pp. 54 - 60
For assessing antibiotic effects, the minimum inhibitory concentration (MIC) neglects that most antibiotics display different rates of bacterial killing.... 
Linezolid | INFECTIOUS DISEASES | Pharmacokinetic/pharmacodynamic modelling | INTERMITTENT | MICROBIOLOGY | INFUSION | Enterococcus faecium | Time kill curves | IN-VITRO | KINETICS | Relative bacterial reduction (RBR) | PHARMACOLOGY & PHARMACY | AGENTS | TIME-KILL | Staphylococcus aureus | BETA-LACTAMS
Journal Article
PHARMACEUTICS, ISSN 1999-4923, 06/2019, Volume 11, Issue 6, p. 278
Increasing rifampicin (RIF) dosages could significantly reduce tuberculosis (TB) treatment durations. Understanding the pharmacokinetic-pharmacodynamics... 
rifampicin | ETHAMBUTOL | tuberculosis | infectious diseases | AIDS | PHARMACODYNAMICS | SIMULATION | high dose | PLASMA | Mycobacterium tuberculosis | POPULATION PHARMACOKINETICS | INTRAPULMONARY CONCENTRATIONS | TREATMENT RESPONSE | GENDER | PHARMACOLOGY & PHARMACY | pharmacokinetic | pharmacodynamic modelling | pharmacokinetic/pharmacodynamic modelling
Journal Article
Applications of Mathematics, ISSN 0862-7940, 4/2019, Volume 64, Issue 2, pp. 253 - 277
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 10/2009, Volume 68, Issue 4, pp. 561 - 573
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Serum concentrations of rituximab influence its clinical efficacy in follicular lymphoma (FL), but its... 
progression-free survival | dose-response relationship | rituximab | pharmacokinetic-pharmacodynamic modelling
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 10/2016, Volume 82, Issue 4, pp. 1011 - 1021
Journal Article
Journal Article
Journal of Psychopharmacology, ISSN 0269-8811, 2/2017, Volume 31, Issue 2, pp. 192 - 203
Journal Article