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Chemico-Biological Interactions, ISSN 0009-2797, 06/2015, Volume 234, pp. 309 - 319
Estrogens have important roles in the pathogenesis of endometrial cancer. They can have carcinogenic effects through stimulation of cell proliferation or... 
Aromatase pathway | Sulfatase pathway | Phase I and phase II estrogen metabolism | Aldo–keto reductase 1C3 (AKR1C3) | 17β-Hydroxysteroid dehydrogenases (17β-HSDs, HSD17B) | Catechol-O-methyl transferase (COMT) | 17b-Hydroxysteroid dehydrogenases | (17b-HSDs HSD17B)Aldoketo reductase 1C3 (AKR1C3) | 17 beta-Hydroxysteroid dehydrogenases (17 beta-HSDs, HSD17B) | DEHYDROGENASES | QUINONES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROGESTERONE ACTION | 17-BETA-ESTRADIOL | CARCINOGENESIS | OVARIAN ENDOMETRIOSIS | Aldo-keto reductase 1C3 (AKR1C3) | ENZYMES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | PHASE-I | CARCINOMA | PRE-RECEPTOR REGULATION | Sulfatases - genetics | Progesterone Reductase - metabolism | Humans | Endometrial Neoplasms - metabolism | Aromatase - metabolism | Catechol O-Methyltransferase - genetics | Hydroxyprostaglandin Dehydrogenases - metabolism | Androstenedione - metabolism | Catechol O-Methyltransferase - metabolism | Aromatase - genetics | Endometrial Neoplasms - genetics | Sulfatases - metabolism | Estrogens - genetics | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Sulfotransferases - metabolism | Estrogens - metabolism | Quinones - pharmacology | Glutathione S-Transferase pi - genetics | Sulfotransferases - genetics | Estrone - genetics | Quinone Reductases - metabolism | Androstenedione - genetics | Glutathione S-Transferase pi - metabolism | Estrogens - biosynthesis | RNA, Messenger - genetics | Transcriptome - genetics | Progesterone Reductase - genetics | Arylsulfotransferase - genetics | Hydroxyprostaglandin Dehydrogenases - genetics | Estrone - analogs & derivatives | Aldo-Keto Reductase Family 1 Member C3 | Estrone - metabolism | Cell Line, Tumor | Quinone Reductases - genetics | 3-Hydroxysteroid Dehydrogenases - genetics | Arylsulfotransferase - metabolism | Physiological aspects | Endometrial cancer | Sulfates | Genes | Estrogen | Steroids | Index Medicus
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 03/2013, Volume 367, Issue 1-2, pp. 74 - 84
► Expression of , , and MB-COMT levels were higher in endometriosis. ► Expression of , , , , and was decreased. ► Three NQO1 isoforms were detected; NQO1c... 
Glutathione S-transferase pi 1 (GSTP1) | (NRH):quinone oxidoreductase 2 (NQO2) | Sulfotransferases (SULTs) | NAD(P)H:quinone oxidoreductase 1 (NQO1) | Cytochrome P450 (CYP) | Catechol-O-methyltransferase (COMT) | ORTHO-QUINONES | CELLS | OXIDATIVE STRESS | HUMAN-BREAST-CANCER | RECEPTOR | CYTOCHROME-P450 ISOFORMS | ESTRONE | 17-BETA-ESTRADIOL | CELL BIOLOGY | CATECHOL-O-METHYLTRANSFERASE | ENDOCRINOLOGY & METABOLISM | EXPRESSION | Immunohistochemistry | Cytochrome P-450 CYP1A1 - genetics | Steroid Hydroxylases - metabolism | Reactive Oxygen Species - metabolism | Endometriosis - genetics | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Gene Expression Profiling | NAD(P)H Dehydrogenase (Quinone) - genetics | Steroid 16-alpha-Hydroxylase - metabolism | Catechol O-Methyltransferase - genetics | Case-Control Studies | Young Adult | Catechol O-Methyltransferase - metabolism | Endometriosis - enzymology | Estrogens - chemistry | Isoenzymes - metabolism | Metabolic Detoxication, Phase II - genetics | Adult | Female | Metabolic Detoxication, Phase I - genetics | Estrogens - metabolism | Steroid Hydroxylases - genetics | Glutathione S-Transferase pi - genetics | Glutathione S-Transferase pi - metabolism | Ovary - pathology | Up-Regulation - genetics | Cytochrome P-450 CYP1A1 - metabolism | Blotting, Western | Aryl Hydrocarbon Hydroxylases - metabolism | Gene Expression Regulation, Enzymologic | Ovary - enzymology | Cytochrome P-450 CYP1B1 | NAD(P)H Dehydrogenase (Quinone) - metabolism | Steroid 16-alpha-Hydroxylase - genetics | Endometriosis | Thiols | Glutathione transferase | Quinone | Cytochrome P-450 | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 45, pp. E10642 - E10651
Women having BRCA1 germ-linemutations develop cancer in breast and ovary, estrogen-regulated tissues, with high penetrance. Binding of estrogens to the... 
Breast cancer | BRCA1 | Estradiol (E2) | HBOC syndrome | Topoisomerase II | COMPREHENSIVE MOLECULAR PORTRAITS | MULTIDISCIPLINARY SCIENCES | BREAST-TUMOR HETEROGENEITY | breast cancer | DOUBLE-STRAND BREAKS | DEFICIENT CELLS | estradiol (E2) | topoisomerase II | REPAIR | CHROMOSOMAL BREAKS | TRANSCRIPTION-REPLICATION CONFLICTS | PROSTATE-CANCER | VERTEBRATE CELLS | HOMOLOGOUS RECOMBINATION | DNA Topoisomerases, Type II - metabolism | Estrogens - physiology | Promoter Regions, Genetic | Receptors, Estrogen - metabolism | Humans | Carcinogenesis - genetics | BRCA1 Protein - physiology | DNA - metabolism | BRCA1 Protein - genetics | G1 Phase | Animals | Breast Neoplasms - genetics | MCF-7 Cells | Mammary Glands, Animal - metabolism | DNA Repair | Female | Mice | DNA Damage | Histones - metabolism | Genomic Instability - genetics | Nucleotide sequencing | Gene mutations | Observations | Methods | DNA sequencing | Transcription | Epithelial cells | Estrogens | DNA damage | Estrogen | Estrogen receptors | Genomes | Ovarian cancer | MRE11 protein | Cell cycle | Tumorigenesis | Catalysis | Mammary gland | Deoxyribonucleic acid--DNA | Adducts | G1 phase | DNA topoisomerase (ATP-hydrolysing) | BRCA1 protein | Etoposide | Mammary glands | Maintenance | Lymphocytes B | Breast | Mutation | Cancer | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2011, Volume 331, Issue 1, pp. 158 - 167
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e14110 - e14110
Background: The role of estrogen and estrogen receptors in oncogenesis has been investigated in various malignancies. Recently our group identified estrogen... 
MOLECULAR-MECHANISM | BREAST-CANCER | CROSS-TALK | GROWTH-FACTOR RECEPTOR | LUNG-CANCER | TYROSINE KINASE | PROSTATE-CANCER CELLS | BIOLOGY | PHASE-II | ENDOCRINE THERAPY RESISTANCE | FACTOR SIGNALING PATHWAYS | Pleural Neoplasms - genetics | Cell Proliferation | Immunoprecipitation | Mesothelioma - pathology | Humans | Estrogen Receptor beta - metabolism | Pleural Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Estrogen Receptor beta - genetics | RNA Interference | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Pleural Neoplasms - pathology | Mesothelioma - genetics | Blotting, Western | Caveolin 1 - metabolism | Microscopy, Confocal | Mesothelioma - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Line, Tumor | Protein Binding | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | Epidermal Growth Factor - pharmacology | Quinazolines - pharmacology | Mitogen-Activated Protein Kinase 1 - metabolism | Cell proliferation | Caveolin-1 | Estrogens | Estrogen | Estrogen receptors | Mesothelioma | AKT protein | Activation | Kinases | Inactivation | Signal transduction | Receptors | Cell activation | Cell growth | Epidermal growth factor | Pathways | Rodents | Tumorigenesis | Gefitinib | Deactivation | Epidermal growth factor receptors | Caveolin | Pharmacology | Chemical compounds | Signaling | Molecular modelling | Internalization | Cell lines | Transduction | Tumors | Index Medicus
Journal Article
International Journal of Gynecologic Cancer, ISSN 1048-891X, 06/2017, Volume 27, Issue 5, pp. 900 - 906
Journal Article
Journal Article