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Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2010, Volume 335, Issue 3, pp. 533 - 545
Doxorubicin (DOX) and daunorubicin (DAUN) are effective anticancer drugs; however, considerable interpatient variability exists in their pharmacokinetics. This... 
DIHYDRODIOL DEHYDROGENASE ISOFORMS | QUINONE REDUCTASE | HUMAN CARBONYL REDUCTASE | ENZYMES | ANTHRACYCLINE-INDUCED CARDIOTOXICITY | SUPERFAMILY | PHARMACOLOGY & PHARMACY | HUMAN LIVER | ALDEHYDE REDUCTASE | SINGLE NUCLEOTIDE POLYMORPHISMS | PROSTAGLANDIN-F SYNTHASE | Aldehyde Reductase - genetics | Humans | Polymorphism, Single Nucleotide - physiology | Mitochondrial Proteins - genetics | NAD(P)H Dehydrogenase (Quinone) - genetics | Hydroxyprostaglandin Dehydrogenases - metabolism | Alcohol Oxidoreductases - genetics | Recombinant Proteins - isolation & purification | Mitochondrial Proteins - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Aldehyde Reductase - metabolism | Hydroxysteroid Dehydrogenases - metabolism | Doxorubicin - metabolism | Daunorubicin - metabolism | Glyceraldehyde - metabolism | Phenanthrenes - metabolism | Recombinant Proteins - metabolism | 20-Hydroxysteroid Dehydrogenases - genetics | Biocatalysis | Oxidoreductases - metabolism | Oxidoreductases - genetics | Gene Frequency | Indans - metabolism | Models, Molecular | Alcohol Oxidoreductases - metabolism | Recombinant Proteins - genetics | Hydroxysteroid Dehydrogenases - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Aldo-Keto Reductases | Vitamin K 3 - metabolism | Aldo-Keto Reductase Family 1 Member C3 | NAD(P)H Dehydrogenase (Quinone) - metabolism | Kinetics | 3-Hydroxysteroid Dehydrogenases - genetics | Index Medicus
Journal Article
Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology, ISSN 0003-6072, 12/2018, Volume 111, Issue 12, pp. 2293 - 2301
Journal Article
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 11/2014, Volume 229, Issue 11, pp. 1595 - 1606
Cancer stem cells (CSCs) are affected by the local micro-environment, the niche, in which inflammatory stimuli and hypoxia act as steering factors. Here, two... 
INVASIVENESS | IN-VITRO | PHYSIOLOGY | PROLIFERATOR-ACTIVATED RECEPTORS | PHENOTYPE | EXOSOMES | DIFFERENTIATION | COMBINATION | EXPRESSION | TUMOR MICROENVIRONMENT | MAMMARY-GLAND | CELL BIOLOGY | Exosomes - drug effects | Exosomes - metabolism | Inflammation - pathology | Neoplastic Stem Cells - drug effects | Stromal Cells - pathology | Humans | Spheroids, Cellular - pathology | NF-kappa B - metabolism | PPAR gamma - metabolism | Apolipoproteins E - metabolism | Carbonic Anhydrases - metabolism | Breast Neoplasms - enzymology | Inflammation - metabolism | Matrix Metalloproteinase 9 - metabolism | MCF-7 Cells | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Stromal Cells - drug effects | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Female | Spheroids, Cellular - drug effects | Thiazolidinediones - pharmacology | Retinoid X Receptors - metabolism | Carbonic Anhydrase IX | Fibroblasts - metabolism | Cell Survival - drug effects | Cell Hypoxia - drug effects | Stromal Cells - metabolism | Fibroblasts - pathology | Phenanthrenes - pharmacology | Breast Neoplasms - pathology | Models, Biological | Retinoid X Receptors - agonists | Fibroblasts - drug effects | Ligands | Stem Cell Niche - drug effects | Neoplastic Stem Cells - enzymology | Receptor Cross-Talk - drug effects | Index Medicus
Journal Article
Environmental Science and Technology, ISSN 0013-936X, 07/2012, Volume 46, Issue 14, pp. 7731 - 7740
Journal Article
The Plant Journal, ISSN 0960-7412, 02/2017, Volume 89, Issue 3, pp. 429 - 441
Tripterygium wilfordii (Celastraceae) is a medicinal plant with anti‐inflammatory and immunosuppressive properties. Identification of a vast array of unusual... 
bioactive diterpenoids | specialized metabolism | Tripterygium wilfordii | convergent evolution | terpene synthase | PLANT | TRIPDIOLIDE | IDENTIFICATION | PLANT SCIENCES | METABOLISM | BIOSYNTHESIS | FUNCTIONAL-ANALYSIS | DETECTING POSITIVE SELECTION | DIVERSITY | EXPRESSION | TRIPTOLIDE | Alkyl and Aryl Transferases - classification | Epoxy Compounds - metabolism | Multigene Family | Intramolecular Lyases - metabolism | Alkyl and Aryl Transferases - metabolism | Plant Roots - genetics | Phylogeny | Phenanthrenes - chemistry | Alkyl and Aryl Transferases - genetics | Molecular Structure | Plant Proteins - metabolism | Diterpenes - metabolism | Phenanthrenes - metabolism | Tripterygium - enzymology | Diterpenes - chemistry | Amino Acid Sequence | Tripterygium - genetics | Diterpenes, Abietane - metabolism | Diterpenes, Abietane - chemistry | Gene Expression Profiling - methods | Sequence Homology, Amino Acid | Plant Proteins - genetics | Intramolecular Lyases - genetics | Epoxy Compounds - chemistry | Monoterpenes - metabolism | Plant Roots - enzymology | Monoterpenes - chemistry | Medicinal plants | Sesquiterpenes | Medicine, Botanic | Physiological aspects | Evolution | Medicine, Herbal | Herbal medicine | Enzymes | Genetics | Biosynthesis | Botany | Index Medicus | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES | Biological Sciences | Naturvetenskap | Botanik | Biologiska vetenskaper | Natural Sciences
Journal Article
Journal Article
Science of the Total Environment, ISSN 0048-9697, 03/2013, Volume 447, pp. 152 - 159
Four different polycyclic aromatic hydrocarbons (naphthalene, phenanthrene, pyrene, chrysene) and their hydroxylated metabolites (1-hydroxynaphthalene,... 
P450 aromatase | Carp | 11β-HSD2 | C17,20-Lyase | CYP11β | PAH metabolites | CLARIAS-GARIEPINUS | FLOUNDER PLATICHTHYS-FLESUS | RAINBOW-TROUT | 11 beta-HSD2 | POLYCYCLIC AROMATIC-HYDROCARBONS | SEX-DIFFERENTIATION | AFRICAN CATFISH | 11-BETA-HYDROXYSTEROID DEHYDROGENASE | ENVIRONMENTAL SCIENCES | IN-VITRO | REPRODUCTIVE STEROIDS | CYP11 beta | TROUT ONCORHYNCHUS-MYKISS | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | Testis - metabolism | Polycyclic Aromatic Hydrocarbons - toxicity | Aromatase - metabolism | Male | Testis - drug effects | Chrysenes - toxicity | Female | Ovary - drug effects | Estrogens - metabolism | Pyrenes - toxicity | Phenanthrenes - metabolism | Ovary - metabolism | Hydroxylation | Pyrenes - metabolism | Carps | Mitochondria - metabolism | Mitochondria - drug effects | Chrysenes - metabolism | Animals | Polycyclic Aromatic Hydrocarbons - metabolism | Water Pollutants, Chemical - toxicity | Polycyclic Aromatic Hydrocarbons - chemistry | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - metabolism | Androstenes - metabolism | Phenanthrenes - toxicity | Steroid 17-alpha-Hydroxylase - metabolism | Androgens - metabolism | Subcellular Fractions | Toxicity Tests | Androgens | Polycyclic aromatic hydrocarbons | Metabolites | Estrogen | Cytochrome P-450 | Index Medicus | Inhibitors | Synthesis | Estrogens | Testes | Gonads
Journal Article
Journal Article