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phenylbiguanide (72) 72
animals (56) 56
biguanides - pharmacology (38) 38
male (38) 38
rats (38) 38
receptors (21) 21
pharmacology & pharmacy (20) 20
reflex - drug effects (19) 19
blood pressure - drug effects (18) 18
neurosciences (18) 18
serotonin receptor agonists - pharmacology (18) 18
5-ht (17) 17
heart rate - drug effects (17) 17
physiology (17) 17
rats, sprague-dawley (17) 17
female (16) 16
serotonin (16) 16
index medicus (13) 13
stimulation (13) 13
serotonin antagonists - pharmacology (12) 12
vagus nerve - physiology (12) 12
receptors, serotonin - drug effects (11) 11
vagus nerve - drug effects (11) 11
5-ht3 receptors (10) 10
brain (10) 10
dopamine - metabolism (9) 9
receptors, serotonin - physiology (9) 9
reflex - physiology (9) 9
responses (9) 9
vagus nerve (9) 9
capsaicin - pharmacology (8) 8
cats (8) 8
receptor (8) 8
reflex (8) 8
vagal afferents (8) 8
5-hydroxytryptamine (7) 7
capsaicin (7) 7
cardiac & cardiovascular systems (7) 7
ondansetron (7) 7
rabbits (7) 7
rat (7) 7
5-ht3 receptor (6) 6
activation (6) 6
bezold-jarisch reflex (6) 6
biochemistry & molecular biology (6) 6
blood pressure - physiology (6) 6
chemoreceptor cells - physiology (6) 6
dose-response relationship, drug (6) 6
microdialysis (6) 6
peripheral vascular disease (6) 6
physiological aspects (6) 6
reflexes (6) 6
sympathetic nervous system - physiology (6) 6
1-phenylbiguanide (5) 5
afferents (5) 5
anesthesia (5) 5
antagonist (5) 5
baroreceptor reflex (5) 5
bradycardia - physiopathology (5) 5
conscious rabbits (5) 5
denervation (5) 5
dopamine (5) 5
dopamine release (5) 5
h-3 dopamine (5) 5
inhibition (5) 5
mechanisms (5) 5
neurons, afferent - drug effects (5) 5
nucleus accumbens (5) 5
nucleus-accumbens (5) 5
rats, inbred strains (5) 5
rats, wistar (5) 5
respiratory system (5) 5
serotonin - pharmacology (5) 5
striatum (5) 5
vagotomy (5) 5
1‐phenylbiguanide (4) 4
5‐ht (4) 4
5‐hydroxytryptamine (4) 4
anesthetized rats (4) 4
bradycardia (4) 4
c-fibers (4) 4
cardiovascular system - drug effects (4) 4
cat (4) 4
corpus striatum - metabolism (4) 4
heart - physiology (4) 4
heart rate - physiology (4) 4
heart-rate (4) 4
in vitro techniques (4) 4
injections (4) 4
kidney - innervation (4) 4
lung - innervation (4) 4
mice (4) 4
nerve fibers - drug effects (4) 4
neurons (4) 4
raphe pallidus (4) 4
receptors, serotonin - metabolism (4) 4
renal sympathetic nerve activity (4) 4
respiration (4) 4
respiration - drug effects (4) 4
spontaneously hypertensive rats (4) 4
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American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 04/2012, Volume 302, Issue 7, pp. R833 - R844
Journal Article
Brain Research, ISSN 0006-8993, 12/2000, Volume 887, Issue 1, pp. 46 - 52
The current study examined whether or not the activation of Bezold-Jarisch reflex with administration of phenylbiguanide (PBG, 100 mu g/kg) into right atrium... 
phenylbiguanide
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 2018, Volume 30, Issue 2, pp. 413 - 417
Cytosolic protein delivery is critical for the development of protein-based therapeutics. However, an efficient and robust carrier that can deliver native... 
DESIGN | FUNCTIONAL PROTEINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | INTRACELLULAR DELIVERY | CHEMISTRY, MULTIDISCIPLINARY | Proteins | Organic chemistry | Endocytosis | Phenylbiguanide | Toxicity | Cytotoxicity | Biocompatibility | Cationic polymerization | Polymers | Drug development | Cytosol
Journal Article
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, ISSN 1386-1425, 01/2017, Volume 170, pp. 256 - 266
Three polymorphic modifications of bis(N-phenylbiguanidium(1+)) oxalate are reported, and their characterization is discussed in this paper. The... 
X-ray diffraction | Second harmonic generation | Thermal behaviour | N-Phenylbiguanide salts | Vibrational spectroscopy | Polymorphism | SPECTROSCOPY | BIGUANIDE COMPLEXES | CRYSTAL-STRUCTURES | SPECTRA | ISOSTRUCTURAL PHASE-TRANSITIONS | HYPOGLYCEMIC AGENTS | Diffraction | Oxalic acid | Analysis | X-rays | Crystals | Oxalates | Raman spectroscopy | Structure
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1900 - 12
Journal Article
International Multidisciplinary Scientific GeoConference Surveying Geology and Mining Ecology Management, SGEM, ISSN 1314-2704, 2015, Volume 1, Issue 6, pp. 259 - 265
Conference Proceeding
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e91763
Sensitization of vagal lung C-fibers (VLCFs) induced by mediators contributes to the pathogenesis of airway hypersensitivity, which is characterized by... 
INHALED WOOD SMOKE | ACID-PEPSIN INSULT | EXHALED BREATH CONDENSATE | OXIDATIVE STRESS | MULTIDISCIPLINARY SCIENCES | ASTHMA | ION CHANNELS | AIRWAY SENSORY NERVES | ANESTHETIZED RATS | AFFERENTS | CAPSAICIN | Bronchoalveolar Lavage Fluid | Oxidants - pharmacology | Reactive Oxygen Species - metabolism | Apnea - metabolism | Electrophysiology | Vagus Nerve - drug effects | Male | Apnea - etiology | Lung - cytology | TRPV Cation Channels - metabolism | Nerve Fibers, Unmyelinated - drug effects | Pulmonary Ventilation - physiology | Receptors, Purinergic P2X - metabolism | Lung - metabolism | Vagus Nerve - metabolism | Pulmonary Ventilation - drug effects | Hydrogen Peroxide - pharmacology | Rats | Rats, Sprague-Dawley | Vagus Nerve - cytology | Blotting, Western | Animals | Apnea - pathology | Nerve Fibers, Unmyelinated - metabolism | Lung - drug effects | TRPA1 Cation Channel | TRPC Cation Channels - metabolism | Conduction | Reactive oxygen species | Hydrogen peroxide | Intravenous administration | Serotonin S3 receptors | Pathogenesis | Capsaicin | Capsaicin receptors | Antagonists | Fibers | Respiratory tract | Nerve conduction | Receptors | Stimulants | Phenylbiguanide | Catalase | Rodents | Hydroxyl radicals | Respiratory tract diseases | Physiology | Vagus nerve | Hypersensitivity | Capsazepine | Inhalation | Methylene | Asthma | Medicine | Studies | Ostomy | Lungs | Laboratory animals | Respiration | ATP
Journal Article
Journal Article
Neuroscience, ISSN 0306-4522, 2007, Volume 146, Issue 2, pp. 756 - 772
Abstract Peripheral immune activation can have profound physiological and behavioral effects including induction of fever and sickness behavior. One mechanism... 
Neurology | raphe | depression | hippocampus | 5-HT | prefrontal cortex | vagus | CEREBRAL CATECHOLAMINE | KILLED MYCOBACTERIUM-VACCAE | BRAIN-STEM | STRESSOR CONTROLLABILITY | NEUROSCIENCES | CELL LUNG-CANCER | MEDIAL PREFRONTAL CORTEX | TOPOGRAPHICALLY ORGANIZED SUBPOPULATIONS | LEARNED HELPLESSNESS | DORSAL RAPHE NUCLEUS | C-FOS EXPRESSION | Brain Chemistry - drug effects | Neural Pathways - drug effects | Bronchopulmonary Sequestration - metabolism | Male | Bronchopulmonary Sequestration - immunology | Limbic System - metabolism | Raphe Nuclei - cytology | Cerebral Cortex - metabolism | Emotions - drug effects | Raphe Nuclei - metabolism | Behavior, Animal | Time Factors | Bronchopulmonary Sequestration - chemically induced | Neurons - metabolism | Bacterial Vaccines - pharmacology | Neural Pathways - immunology | Disease Models, Animal | Emotions - physiology | Drug Administration Routes | Cytokines - metabolism | Limbic System - immunology | Animals | Raphe Nuclei - drug effects | Analysis of Variance | Bacterial Vaccines - administration & dosage | Cerebral Cortex - immunology | Serotonin - metabolism | Neural Pathways - metabolism | Mice | Mice, Inbred BALB C | Antigens | Neurosciences | Laws, regulations and rules | Analysis | Physiological aspects | Albumin | Biogenic amines | S.E.M., standard error of the mean | EDTA, ethylenediaminetetraacetic acid | ROb, raphe obscurus | EMG, electromyogram | Mv-NC, Mycobacterium vaccae antigen, M. vaccae coupled to nitrocellulose beads | NC, nitrocellulose beads | PBG, phenylbiguanide | PBS, phosphate-buffered saline | SolDL, dorsolateral part of the nucleus of the solitary tract | IL-6, interleukin-6 | 5-HT, serotonin | ANOVA, analysis of variance | mlf, medial longitudinal fasciculus | PBST, phosphate-buffered saline containing 0.3% Triton X-100 | ECG, electrocardiogram | nTS, nucleus of the solitary tract | LSD, least significant difference | Treg, T regulatory cell | Neuroanatomy | AP, area postrema | DRC, dorsal raphe nucleus, caudal part | OVA-NC, ovalbumin coupled to nitrocellulose beads | DR, dorsal raphe nucleus | IL-10, interleukin-10 | Th2, T helper cell 2 | HPLC, high pressure liquid chromatography | TNF-α, tumor necrosis factor-α | M. vaccae, Mycobacterium vaccae | TGF-β, transforming growth factor-β | i.t., intratracheal | c-Fos-ir, c-Fos-like-immunoreactive | OVA, ovalbumin | 5-HIAA, 5-hydroxyindoleacetic acid | LPS, lipopolysaccharide | Th1, T helper cell 1 | DRI, dorsal raphe nucleus, interfascicular part | RMg, raphe magnus
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2002, Volume 282, Issue 2, pp. 482 - 490
Injections of the thromboxane A2 mimetic U-46619 (10 and 20 μg) into the left atrium of anesthetized rabbits evoked decreases in heart rate (HR) and arterial... 
Prostaglandins | Coronary chemoreflex | Phenylbiguanide | Anesthetized rabbits
Journal Article
Journal Article
Journal Article
Neuroscience Letters, ISSN 0304-3940, 2006, Volume 409, Issue 1, pp. 70 - 74
The involvement of 5-hydroxytryptaminergic (5-HT) system for the Ptychodiscus brevis toxin (PbTx)-induced depression of spinal reflexes was evaluated. The... 
Brevetoxin | Spinal cord | Phenylbiguanide | Synaptic transmission | Serotonin receptors | Monosynaptic reflex | Polysynaptic reflex
Journal Article