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1. Full Text Metal-organic framework-templated synthesis of magnetic nanoporous carbon as an efficient absorbent for enrichment of phenylurea herbicides
by Liu, Xingli and Wang, Chun and Wu, Qiuhua and Wang, Zhi
Analytica chimica acta, ISSN 0003-2670, 04/2015, Volume 870, Issue 1, pp. 67 - 74
Phenylurea herbicides | Magnetic solid-phase extraction | Magnetic nanoporous carbon | High performance liquid chromatography | Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Vitis - chemistry | Nanotechnology - methods | Solvents - chemistry | Herbicides - chemistry | Molecular Conformation | Momordica charantia - chemistry | Phenylurea Compounds - isolation & purification | Magnets - chemistry | Models, Molecular | Carbon - chemistry | Herbicides - isolation & purification | Adsorption | Nitrogen - chemistry | Phenylurea Compounds - chemistry | Surface Properties | Organometallic Compounds - chemistry | Porosity | Cobalt - chemistry | Herbicides | Index Medicus
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2. Full Text Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety
by Hrafnsdottir, Sigrun and Burgin, Alex B and Magnusson, Olafur T and Staker, Bart L and Kiselyov, Alex S and Gurney, Mark E and Hagen, Timothy and Stewart, Lance J and Thorsteinsdottir, Margret and Singh, Jasbir and Witte, Pam and Bjornsson, Jon M
Nature biotechnology, ISSN 1087-0156, 01/2010, Volume 28, Issue 1, pp. 63 - 70
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Phosphodiesterase Inhibitors - therapeutic use | Phosphodiesterase Inhibitors - adverse effects | Humans | Molecular Sequence Data | Crystallography, X-Ray | Structure-Activity Relationship | Benzhydryl Compounds - chemistry | Benzhydryl Compounds - adverse effects | Phenylurea Compounds - adverse effects | Phenylurea Compounds - chemistry | Drug Design | Phosphodiesterase 4 Inhibitors | Behavior, Animal - drug effects | Biological Assay | Phosphodiesterase Inhibitors - chemistry | Benzhydryl Compounds - therapeutic use | Cyclic Nucleotide Phosphodiesterases, Type 4 - chemistry | Disease Models, Animal | Allosteric Regulation - drug effects | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Catalytic Domain | Models, Molecular | Phenylurea Compounds - therapeutic use | Phosphodiesterase Inhibitors - pharmacology | Vomiting - drug therapy | Cognition - drug effects | Animals | Benzhydryl Compounds - pharmacology | Mice | Phenylurea Compounds - pharmacology | Kinetics | Care and treatment | Schizophrenia | Physiological aspects | Genetic aspects | Cellular signal transduction | Cyclic adenylic acid | Research | Phosphodiesterases | Enzymes | Biotechnology | Cellular biology | Molecular biology | Cognitive ability | Crystal structure | Index Medicus
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3. Full Text Conformationally Constrained ortho-Anilino Diaryl Ureas: Discovery of 1‑(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent, Selective, and Bioavailable P2Y1 Antagonist
by Qiao, Jennifer X and Wang, Tammy C and Ruel, Réjean and Thibeault, Carl and L’Heureux, Alexandre and Schumacher, William A and Spronk, Steven A and Hiebert, Sheldon and Bouthillier, Gilles and Lloyd, John and Pi, Zulan and Schnur, Dora M and Abell, Lynn M and Hua, Ji and Price, Laura A and Liu, Eddie and Wu, Qimin and Steinbacher, Thomas E and Bostwick, Jeffrey S and Chang, Ming and Zheng, Joanna and Gao, Qi and Ma, Baoqing and McDonnell, Patricia A and Huang, Christine S and Rehfuss, Robert and Wexler, Ruth R and Lam, Patrick Y. S
Journal of medicinal chemistry, ISSN 0022-2623, 11/2013, Volume 56, Issue 22, pp. 9275 - 9295
Urea - pharmacokinetics | Humans | Molecular Conformation | Biological Availability | Urea - chemistry | Purinergic P2Y Receptor Antagonists - metabolism | Phenylurea Compounds - chemistry | Receptors, Purinergic P2Y1 - metabolism | Drug Design | Receptors, Purinergic P2Y1 - chemistry | Urea - metabolism | Phenylurea Compounds - metabolism | Phenylurea Compounds - pharmacokinetics | Spiro Compounds - chemistry | Purinergic P2Y Receptor Antagonists - pharmacology | Purinergic P2Y Receptor Antagonists - pharmacokinetics | Models, Molecular | Rats | Rats, Sprague-Dawley | Spiro Compounds - pharmacokinetics | Sequence Homology, Amino Acid | Animals | Purinergic P2Y Receptor Antagonists - chemistry | Phenylurea Compounds - pharmacology | Indoles - chemistry | Spiro Compounds - pharmacology | Urea - pharmacology | Spiro Compounds - metabolism | Index Medicus
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4. Full Text Dispersive liquid—liquid microextraction for the determination of three cytokinin compounds in fruits and vegetables by liquid chromatography with time-of-flight mass spectrometry
by Campillo, N and Viñas, P and Férez-Melgarejo, G and Hernández-Córdoba, M
Talanta (Oxford), ISSN 0039-9140, 11/2013, Volume 116, pp. 376 - 381
1,3-Diphenylurea | Thidiazuron | Dispersive liquid—liquid microextraction (DLLME) | Liquid chromatography with time-of-flight mass spectrometry (LC—TOFMS) | Forchlorfenuron | Fruits | Liquid chromatography with time-of-flight mass spectrometry (LC - TOFMS) | Dispersive liquid - liquid microextraction (DLLME) | Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Limit of Detection | Vitis - chemistry | Citrullus - chemistry | Ethanol | Liquid Phase Microextraction - methods | Fruit - chemistry | Phenylurea Compounds - isolation & purification | Environmental Pollutants - isolation & purification | Factor Analysis, Statistical | Actinidia - chemistry | Vegetables - chemistry | Spectrometry, Mass, Electrospray Ionization | Acetonitriles | Thiadiazoles - isolation & purification | Lycopersicon esculentum - chemistry | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Carbanilides - isolation & purification | Ethylene Dichlorides | Pyridines - isolation & purification | Nitriles | Liquid chromatography | Vegetables | Mass spectrometry | Analysis | Index Medicus
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5. Full Text Phosphorous-enriched knitting aryl network polymer for the rapid and effective adsorption of aromatic compounds
by Wang, Qianqian and Zhang, Lihong and Hao, Lin and Wang, Chun and Wu, Qiuhua and Wang, Zhi
Journal of Chromatography A, ISSN 0021-9673, 11/2018, Volume 1575, pp. 18 - 25
Knitting aryl network polymer | Solid phase extraction adsorbent | Phenylurea pesticides | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Organic Chemicals - isolation & purification | Limit of Detection | Food Analysis - methods | Environmental Monitoring - methods | Organic Chemicals - chemistry | Phosphorus - chemistry | Fresh Water - chemistry | Chromatography, High Pressure Liquid | Water Pollutants, Chemical - isolation & purification | Pesticides - isolation & purification | Adsorption | Solid Phase Extraction | Polymers - chemistry | Lycopersicon esculentum - chemistry | Cucumis sativus - chemistry | Crosslinked polymers | Benzene | Knitting | Polymer industry | Polymers | Formaldehyde
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6. Full Text Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites
by Fujita, Ken-ichi and Masuo, Yusuke and Yamazaki, Erina and Shibutani, Toshiki and Kubota, Yutaro and Nakamichi, Noritaka and Sasaki, Yasutsuna and Kato, Yukio
Journal of pharmaceutical sciences, ISSN 0022-3549, 09/2017, Volume 106, Issue 9, pp. 2632 - 2641
P-glycoprotein | skin | tissue partition | ABC transporters | transporters | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Chemistry, Multidisciplinary | Science & Technology | Diketopiperazines - chemistry | Pyridines - chemistry | Skin - metabolism | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Male | Phenylurea Compounds - toxicity | Heterocyclic Compounds, 4 or More Rings - pharmacology | Breast Neoplasms - metabolism | Antineoplastic Agents - metabolism | Tissue Distribution | Protein Kinase Inhibitors - chemistry | Biological Transport | Tetrahydroisoquinolines - chemistry | Phenylurea Compounds - chemistry | Antineoplastic Agents - pharmacology | Phenylurea Compounds - metabolism | Acridines - chemistry | Tetrahydroisoquinolines - pharmacology | Acridines - metabolism | Heterocyclic Compounds, 4 or More Rings - chemistry | Diketopiperazines - pharmacology | Antineoplastic Agents - chemistry | Breast Neoplasms - drug therapy | Animals | Pyridines - metabolism | Pyridines - toxicity | Tetrahydroisoquinolines - metabolism | Acridines - pharmacology | Heterocyclic Compounds, 4 or More Rings - metabolism | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Diketopiperazines - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Index Medicus
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7. Full Text Differential Effects of Thidiazuron on Production of Anticancer Phenolic Compounds in Callus Cultures of Fagonia indica
by Khan, Tariq and Abbasi, Bilal Haider and Khan, Mubarak Ali and Shinwari, Zabta Khan
Applied biochemistry and biotechnology, ISSN 0273-2289, 4/2016, Volume 179, Issue 1, pp. 46 - 58
Biochemistry, general | Biotechnology | Chemistry | Callus | Fagonia | TDZ | Anticancer | Phenolic acids | HPLC | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Plant Leaves - chemistry | Plant Extracts - chemistry | Bony Callus - drug effects | Bony Callus - growth & development | Antioxidants - chemistry | Zygophyllaceae - chemistry | Plant Extracts - pharmacology | Antioxidants - pharmacology | Phenols - metabolism | Antineoplastic Agents - chemistry | Zygophyllaceae - drug effects | Antineoplastic Agents - metabolism | Zygophyllaceae - cytology | Zygophyllaceae - metabolism | Phenols - chemistry | Phenylurea Compounds - pharmacology | Cell Culture Techniques | Bony Callus - metabolism | Flavonoids - chemistry | Thiadiazoles - pharmacology | Care and treatment | Flavonoids | Flavones | Bioflavonoids | Plant hormones | Plant metabolites | High performance liquid chromatography | Cancer | Herbal medicine | Biomass | Acids | Cancer therapies | Index Medicus
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8. Full Text Substructure-activity relationship studies on antibody recognition for phenylurea compounds using competitive immunoassay and computational chemistry
by Zhang, Fuyuan and Liu, Bing and Liu, Guozhen and Zhang, Yan and Wang, Junping and Wang, Shuo
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 3131 - 8
Bovine serum albumin | Herbicides | Molecular modelling | Quantum chemistry | Correlation analysis | Cross-reactivity | Computer applications | Antibodies | Phenylurea | Electrostatic properties | Index Medicus
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9. Full Text A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase
by Matyskiela, Mary E and Lu, Gang and Ito, Takumi and Pagarigan, Barbra and Lu, Chin-Chun and Miller, Karen and Fang, Wei and Wang, Nai-Yu and Nguyen, Derek and Houston, Jack and Carmel, Gilles and Tran, Tam and Riley, Mariko and Nosaka, Lyn'Al and Lander, Gabriel C and Gaidarova, Svetlana and Xu, Shuichan and Ruchelman, Alexander L and Handa, Hiroshi and Carmichael, James and Daniel, Thomas O and Cathers, Brian E and Lopez-Girona, Antonia and Chamberlain, Philip P
Nature (London), ISSN 0028-0836, 07/2016, Volume 535, Issue 7611, pp. 252 - 257
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Substrate Specificity | Crystallography, X-Ray | Thalidomide - pharmacology | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | Proteolysis - drug effects | Thalidomide - analogs & derivatives | Phenylurea Compounds - chemistry | Antineoplastic Agents - pharmacology | Ikaros Transcription Factor - metabolism | Binding Sites | Peptide Hydrolases - metabolism | Ikaros Transcription Factor - chemistry | Thalidomide - chemistry | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Antineoplastic Agents - chemistry | Ubiquitin-Protein Ligases - chemistry | DNA-Binding Proteins - chemistry | Peptide Termination Factors - metabolism | Peptide Hydrolases - chemistry | Amino Acid Motifs | Multiprotein Complexes - chemistry | Protein Binding | Peptide Termination Factors - chemistry | Phenylurea Compounds - pharmacology | Peptide Termination Factors - deficiency | Index Medicus
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10. Full Text Converting homogeneous to heterogeneous in electrophilic catalysis using monodisperse metal nanoparticles
by Witham, Cole A and Huang, Wenyu and Toste, F. Dean and Tsung, Chia-Kuang and Somorjai, Gabor A and Kuhn, John N
Nature chemistry, ISSN 1755-4330, 01/2010, Volume 2, Issue 1, pp. 36 - 41
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Iodine - chemistry | Phenylurea Compounds - chemical synthesis | Cyclization | Oxidation-Reduction | Phenylurea Compounds - chemistry | Metal Nanoparticles - chemistry | Silicon Dioxide - chemistry | Dendrimers - chemistry | Catalysis | Palladium - chemistry | Platinum - chemistry | Index Medicus
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11. Full Text Nanosuspension for improving the bioavailability of a poorly soluble drug and screening of stabilizing agents to inhibit crystal growth
by Ghosh, Indrajit and Bose, Sonali and Vippagunta, Radha and Harmon, Ferris
International journal of pharmaceutics, ISSN 0378-5173, 2011, Volume 409, Issue 1, pp. 260 - 268
Nanosuspension | Poorly soluble compound | Rod shape crystals | Nanomilling | Vitamin E TPGS | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Pharmaceutical technology. Pharmaceutical industry | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Methylcellulose - analogs & derivatives | Vitamin E - analogs & derivatives | Biological Availability | Male | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Nanoparticles | Excipients - chemistry | Phenylurea Compounds - chemistry | Phenylurea Compounds - pharmacokinetics | Vitamin E - chemistry | Suspensions | Benzodiazepinones - administration & dosage | Drug Stability | Crystallization | Solubility | Benzodiazepinones - chemistry | Particle Size | Methylcellulose - chemistry | Animals | Phenylurea Compounds - administration & dosage | Hypromellose Derivatives | Benzodiazepinones - pharmacokinetics | Dogs | Hydrophobic and Hydrophilic Interactions | Index Medicus
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