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Journal Article
Journal Article
The Journal of neuroscience, ISSN 0270-6474, 02/1998, Volume 18, Issue 3, pp. 868 - 877
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 11/2007, Volume 35, Issue 11, pp. 2119 - 2126
Predicting drug-drug interactions requires an assessment of the drug concentration available to the enzyme active site, both in vivo, and within an in vitro... 
Tolbutamide - pharmacology | Cytochrome P-450 Enzyme Inhibitors | Cytochrome P-450 CYP3A | Microsomes, Liver - metabolism | Cytochrome P-450 Enzyme System - metabolism | Dextromethorphan - metabolism | Male | Fluconazole - metabolism | Quinine - pharmacology | Microsomes, Liver - enzymology | Tolbutamide - metabolism | Fluoxetine - pharmacology | Dextromethorphan - pharmacology | Enzyme Inhibitors - metabolism | Enzyme Inhibitors - pharmacology | Fluvoxamine - pharmacokinetics | Ketoconazole - pharmacokinetics | Rats | Rats, Sprague-Dawley | Catalysis - drug effects | Miconazole - pharmacokinetics | Miconazole - pharmacology | Fluoxetine - metabolism | Cytochrome P-450 CYP2D6 - metabolism | Kinetics | Midazolam - pharmacology | Hepatocytes - enzymology | Cytochrome P-450 CYP2D6 Inhibitors | Quinine - pharmacokinetics | Fluconazole - pharmacology | Tolbutamide - pharmacokinetics | Fluoxetine - pharmacokinetics | Ketoconazole - metabolism | Hepatocytes - metabolism | Ketoconazole - pharmacology | Hepatocytes - cytology | Enzyme Inhibitors - pharmacokinetics | Phenytoin - pharmacology | Dextromethorphan - pharmacokinetics | Phenytoin - metabolism | Quinine - metabolism | Fluvoxamine - metabolism | Cells, Cultured | Midazolam - pharmacokinetics | Fluvoxamine - pharmacology | Miconazole - metabolism | Fluconazole - pharmacokinetics | Animals | Midazolam - metabolism | Phenytoin - pharmacokinetics | Index Medicus
Journal Article
Epilepsia (Copenhagen), ISSN 0013-9580, 01/2014, Volume 55, Issue 1, pp. 184 - 192
Summary Purpose The contribution of glial cells, mainly astrocytes and microglia, to the pathophysiology of epilepsy is increasingly appreciated. Glia play a... 
Astroglia | Cytokines | Inflammation | Connexin 43 | Glia | Antiepileptic drugs | Cellular viability | Microglia | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Gabapentin | Rats, Wistar | Coculture Techniques | Epilepsy - physiopathology | Anticonvulsants - pharmacology | Epilepsy - etiology | Valproic Acid - pharmacology | Neuroglia - drug effects | Dose-Response Relationship, Drug | Microglia - physiology | Inflammation - drug therapy | Amines - therapeutic use | Phenytoin - pharmacology | Valproic Acid - therapeutic use | gamma-Aminobutyric Acid - therapeutic use | Transforming Growth Factor beta1 - biosynthesis | Astrocytes - drug effects | Carbamazepine - pharmacology | Cyclohexanecarboxylic Acids - therapeutic use | Enzyme-Linked Immunosorbent Assay | Microglia - drug effects | Cells, Cultured | Neuroglia - physiology | Anticonvulsants - therapeutic use | Carbamazepine - therapeutic use | Connexin 43 - biosynthesis | Rats | gamma-Aminobutyric Acid - pharmacology | Blotting, Western | Astrocytes - physiology | Animals | Gap Junctions - physiology | Phenytoin - therapeutic use | Cyclohexanecarboxylic Acids - pharmacology | Epilepsy - drug therapy | Gap Junctions - drug effects | Amines - pharmacology | Inflammation - physiopathology | Drugs | Enzymes | Divalproex | Analysis | Epilepsy | Bone morphogenetic proteins | Cytochemistry | Valproic acid | Drug therapy | Transforming growth factors | Tumor necrosis factor-TNF | Drug dosages | Rodents | Index Medicus | Antiepileptic agents
Journal Article
The Annals of pharmacotherapy, ISSN 1542-6270, 06/2016, Volume 32, Issue 5, pp. 554 - 563
OBJECTIVE: TO describe the primary types of antiepileptic drug (AED)interactions by using a mechanistic approach. DATA SOURCES: A literature search was... 
Antiepileptics |