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PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 8, p. e0135111
Exosomes deliver functional proteins and genetic materials to neighboring cells, and have potential applications for tissue regeneration... 
PROGENITOR CELLS | TRAUMATIC BRAIN-INJURY | REGENERATION | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | SCIATIC-NERVE INJURY | SPINAL-CORD-INJURY | PROLIFERATION | MEDIATED TRANSFER | STROMAL CELLS | MICRORNA EXPRESSION | Oligonucleotide Array Sequence Analysis | Melanoma, Experimental - chemistry | Humans | Culture Media, Conditioned - chemistry | Culture Media, Conditioned - pharmacology | MicroRNAs - metabolism | Neurons - cytology | Gene Expression Profiling | PC12 Cells | Mesenchymal Stromal Cells - cytology | Bone Marrow Cells - drug effects | Neurons - metabolism | Neurons - drug effects | Mesenchymal Stromal Cells - drug effects | Bone Marrow Cells - cytology | Gene Expression Regulation | Mesenchymal Stromal Cells - metabolism | Rats | Animals | Cell Differentiation - drug effects | Cell Line, Tumor | Exosomes - chemistry | Mice | MicroRNAs - genetics | Primary Cell Culture | Bone Marrow Cells - metabolism | Physiological aspects | Genetic aspects | Research | Cell differentiation | Neurons | Stem cells | Transplants & implants | Mesenchyme | Amino acids | Exosomes | Kinases | Neurogenesis | Proteins | Cell growth | miRNA | Growth factors | Biomedical engineering | Tissue engineering | Melanoma | Ribonucleic acid--RNA | Progenitor cells | Regeneration | DNA microarrays | Microscopy | MicroRNAs | Cells (biology) | Pheochromocytoma cells | Neural stem cells | Spinal cord injuries | Differentiation | Cancer | RNA | Ribonucleic acid
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 9, p. e108925
...) progression is poorly understood. In this study, we investigated the ability of prostate tumor-derived exosomes to downregulate NKG2D expression on natural killer (NK) and CD8(+) T cells... 
IMMUNORECEPTOR | APOPTOSIS | CANCER-PATIENTS | LIGANDS | VESICLES | MULTIDISCIPLINARY SCIENCES | MICROVESICLES | RECEPTOR | IMMUNOSURVEILLANCE | RELEASE | CYTOTOXICITY | Exosomes - metabolism | Cell Line | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | NK Cell Lectin-Like Receptor Subfamily K - chemistry | Antibodies, Monoclonal - pharmacology | Humans | Histocompatibility Antigens Class I - immunology | Intracellular Signaling Peptides and Proteins - immunology | Male | Intracellular Signaling Peptides and Proteins - metabolism | Down-Regulation - drug effects | Histocompatibility Antigens Class I - metabolism | Castration | NK Cell Lectin-Like Receptor Subfamily K - metabolism | Leukocytes, Mononuclear - immunology | Immune Evasion - drug effects | K562 Cells | CD8-Positive T-Lymphocytes - metabolism | Killer Cells, Natural - immunology | Leukocytes, Mononuclear - cytology | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | Antibodies, Monoclonal - immunology | Plasma | Flow cytometry | Regulators | Toxicity | CD8 antigen | Cytotoxicity | Lymphocytes T | Exosomes | Cancer therapies | Proteins | Killer cells | Immunology | Lymphocytes | Rodents | Natural killer cells | Incubation | T cell receptors | Patients | Pathology | Cytometry | Surveillance | Pheochromocytoma cells | Ligands | Aberration | Prostate cancer | Prostate | Cancer | Apoptosis | Tumors
Journal Article
Cell and Tissue Research, ISSN 0302-766X, 6/2018, Volume 372, Issue 3, pp. 629 - 629
...CORRECTION Correction to: Expression and regulation of M-type K + channel in PC12 cells and rat adrenal medullary cells Keita Harada 1 & Hidetada Matsuoka 1... 
Human Genetics | Molecular Medicine | Biomedicine | Proteomics | Pheochromocytoma cells | Potassium channels
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e92917
It has been proposed that differential activation kinetics allows cells to use a common set of signaling pathways to specify distinct cellular outcomes... 
PHEOCHROMOCYTOMA CELLS | SIGNALING PATHWAYS | ACTIVATED PROTEIN-KINASE | MAP KINASE | MULTIDISCIPLINARY SCIENCES | NEURONAL DIFFERENTIATION | MAMMALIAN-CELLS | PLASMA-MEMBRANE | NUCLEAR TRANSLOCATION | NERVE GROWTH-FACTOR | LIVING CELLS | NIH 3T3 Cells | Protein Transport - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | raf Kinases - metabolism | PC12 Cells | Light | Cell Membrane - metabolism | Cell Membrane - drug effects | Neurites - drug effects | Cell Membrane - radiation effects | Cryptochromes - metabolism | Cell Differentiation - radiation effects | Protein Structure, Tertiary | MAP Kinase Signaling System - radiation effects | Proto-Oncogene Proteins c-raf | Nerve Growth Factor - pharmacology | Rats | MAP Kinase Kinase Kinases - metabolism | Neurites - metabolism | Enzyme Activation - drug effects | Enzyme Activation - radiation effects | Animals | MAP Kinase Signaling System - drug effects | Cell Differentiation - drug effects | Protein Transport - radiation effects | Cryptochromes - chemistry | Mice | Kinetics | Dose-Response Relationship, Radiation | Neurites - radiation effects | Nerve growth factor | Cellular signal transduction | Epidermal growth factor | Protein-protein interactions | Phosphorylation | Raf protein | Stimulation | Activation | Kinases | Proteins | Signal transduction | Cell growth | Cell cycle | Localization | Growth factors | Axonogenesis | Extracellular signal-regulated kinase | Gene expression | Studies | Signaling | Cell lines | Pheochromocytoma cells | Transduction | Genetic engineering | Protein interaction
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e90667
Journal Article
Nature cell biology, ISSN 1476-4679, 2015, Volume 17, Issue 10, pp. 1317 - 1326
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 6, p. e65624
.... To study pheochromocytomas, we developed a stable progenitor pheochromocytoma cell line derived from a primary human tumor. Methods... 
LUNG-CANCER | SPECIMENS | EPITHELIAL-CELLS | GENE | TELOMERASE | MULTIDISCIPLINARY SCIENCES | PARAGANGLIOMA | MUTATIONS | EXPRESSION | IMMORTALIZATION | NERVE GROWTH-FACTOR | Pheochromocytoma - metabolism | Transduction, Genetic | Humans | Transcriptome | Immunophenotyping | Abnormal Karyotype | Gene Knockdown Techniques | Telomerase - genetics | Neoplastic Stem Cells - metabolism | RNA Interference | Cell Line, Tumor | Neoplastic Stem Cells - pathology | Pheochromocytoma - pathology | Adult | Female | Pheochromocytoma - genetics | Telomerase - metabolism | Cell Line, Transformed | Hypertension | Epinephrine | Enzymes | Pheochromocytoma | Corticosteroids | Development and progression | Nerve growth factor | Cells | Analysis | Bone morphogenetic proteins | Health aspects | Telomerase | Tumors | Cell culture | Telomerase reverse transcriptase | RNA-directed DNA polymerase | Adrenal glands | Lung cancer | Methyltransferase | Immunoblotting | Oncology | Kinases | Cancer therapies | Cell adhesion molecules | Proteins | Clonal deletion | Rodents | Surgery | N-Methyltransferase | Cell cycle | Cell adhesion | Catalysis | Urine | Medical research | Bone morphogenetic protein 4 | Dexamethasone | Neural cell adhesion molecule | Gene expression | CD31 antigen | Endothelial cells | Phenylethanolamine N-methyltransferase | Pathology | Molecular modelling | Cells (biology) | Pheochromocytoma cells | Biomarkers | Neural stem cells | Informed consent | Hypoxia | Acid phosphatase (tartrate-resistant) | Norepinephrine | Immunofluorescence | Endocrinology
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1, p. 38332
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 3, p. e17850
Background: The existence of cancer stem cells (CSCs) or cancer stem-like cells in a tumor mass is believed to be responsible for tumor recurrence because of their intrinsic and extrinsic drug-resistance characteristics... 
EPITHELIAL-MESENCHYMAL TRANSITION | STEM-CELLS | CARCINOGENESIS | CURCUMIN | BIOLOGY | DRUG-RESISTANCE | INHIBITORS | MICRORNA-21 | NF-KAPPA-B | EXPRESSION | CARCINOMA | Curcumin - analogs & derivatives | Humans | Cell Aggregation - drug effects | Deoxycytidine - pharmacology | MicroRNAs - metabolism | NF-kappa B - metabolism | Antineoplastic Agents - therapeutic use | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Epithelial Cell Adhesion Molecule | Pancreatic Neoplasms - drug therapy | Hyaluronan Receptors - metabolism | Antigens, Neoplasm - metabolism | Antineoplastic Agents - pharmacology | Clone Cells | Gene Expression Regulation, Neoplastic - drug effects | Cell Survival - drug effects | PTEN Phosphohydrolase - genetics | Curcumin - therapeutic use | Neoplasm Invasiveness | Pancreatic Neoplasms - pathology | RNA, Messenger - genetics | Curcumin - pharmacology | Pancreatic Neoplasms - enzymology | PTEN Phosphohydrolase - metabolism | Pancreatic Neoplasms - genetics | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion Molecules - metabolism | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | MicroRNAs - genetics | Deoxycytidine - analogs & derivatives | Drug Resistance, Neoplasm - drug effects | Analysis | Oncology, Experimental | Stem cells | Research | Drug resistance | Vascular endothelial growth factor | Tumors | Apoptosis | Cancer | Gemcitabine | Disintegration | Colorectal cancer | Stem cell transplantation | Oncology | Inactivation | Cancer therapies | Anticancer properties | Prevention | Allografts | Antitumor agents | Mouse devices | CD44 antigen | Animal tissues | Xenografts | Inhibition | Pancreas | Drug dosages | Deoxyribonucleic acid--DNA | Killing | Enzymes | NF-κB protein | Deactivation | Hematology | Cloning | Bioavailability | Gene expression | Pathology | Signaling | Chemotherapy | MicroRNAs | Medical prognosis | Pancreatic cancer | Pheochromocytoma cells | Cyclooxygenase-2 | Prostate cancer | PTEN protein | Animal models | Signal transduction | NF- Kappa B protein | DNA | Deoxyribonucleic acid
Journal Article