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1. Full Text Enhanced steatosis by nuclear receptor ligands: A study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile
by Moya, Marta and José Gómez-Lechón, M and Castell, José V and Jover, Ramiro
Chemico-biological interactions, ISSN 0009-2797, 2010, Volume 184, Issue 3, pp. 376 - 387
Cultured human hepatocytes | HepG2 | NAFLD | Fatty acids | Nuclear receptor ligands | Steatosis | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Vitamin A - pharmacology | Farnesol - pharmacology | Humans | Hepatocytes - metabolism | PPAR gamma - metabolism | Terpenes - pharmacology | Phloroglucinol - pharmacology | Indoles - pharmacology | Hepatocytes - drug effects | Cholesterol - analogs & derivatives | Fatty Liver - metabolism | Bridged Bicyclo Compounds - pharmacology | Androstenols - pharmacology | Cells, Cultured | Receptors, Cytoplasmic and Nuclear - genetics | Calcifediol - pharmacology | Fatty Liver - drug therapy | Hep G2 Cells | Pregnenediones - pharmacology | PPAR gamma - agonists | Tamoxifen - pharmacology | Cholesterol - pharmacology | Ligands | Phloroglucinol - analogs & derivatives | Selective Estrogen Receptor Modulators - pharmacology | Receptors, Cytoplasmic and Nuclear - metabolism | Phosphates | Cell research | Corticosteroids | Liver diseases | Estrogen | Albumin | Triglycerides | Hepatoma | Retinoids | Tamoxifen | Messenger RNA | Synthesis | Choline | Physiological aspects | Progesterone | Rifampin | Protein binding | Index Medicus
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2. Full Text Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: A promising new molecular pattern for the development of antidepressant drugs
by Stein, Ana C and Viana, Alice F and Müller, Liz G and Nunes, Jéssica M and Stolz, Eveline D and Do Rego, Jean-Claude and Costentin, Jean and von Poser, Gilsane L and Rates, Stela M.K
Behavioural brain research, ISSN 0166-4328, 2012, Volume 228, Issue 1, pp. 66 - 73
Antidepressant | Forced swimming test | Monoaminergic neurotransmission | Uliginosin B | Hypericum polyanthemum | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Behavioral Sciences | Science & Technology | Plant Extracts - chemistry | Vesicular Monoamine Transport Proteins - metabolism | Rats, Wistar | Drug Evaluation, Preclinical - psychology | Plant Extracts - pharmacology | Male | Sulpiride | Antidepressive Agents - isolation & purification | Yohimbine - pharmacology | Prazosin - pharmacology | Phloroglucinol - isolation & purification | Phloroglucinol - pharmacology | Immobility Response, Tonic - drug effects | Antidepressive Agents - pharmacology | Fenclonine - pharmacology | Locomotion - drug effects | Drug Evaluation, Preclinical - methods | Fluoxetine - pharmacology | Enzyme Inhibitors - pharmacology | Phloroglucinol - antagonists & inhibitors | Rats | Benzazepines - pharmacology | Mice, Inbred Strains | Animals | Bupropion - pharmacology | Mice | Biogenic Monoamines - metabolism | Imipramine - pharmacology | Phloroglucinol - analogs & derivatives | Receptors, Catecholamine - antagonists & inhibitors | Hypericum - chemistry | Antidepressants, Tricyclic | Index Medicus
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3. Full Text Inhibitory effect of the antidepressant St. John's Wort ( hypericum perforatum) on rat bladder contractility in vitro
by Capasso, Raffaele and Borrelli, Francesca and Capasso, Francesco and Mascolo, Nicola and Izzo, Angelo A
Urology (Ridgewood, N.J.), ISSN 0090-4295, 2004, Volume 64, Issue 1, pp. 168 - 172
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Electric Stimulation | Rats, Wistar | Capsaicin - pharmacology | Plant Extracts - pharmacology | Hypericum | Rutin - pharmacology | Male | Methysergide - pharmacology | Adenosine Triphosphate - pharmacology | Terpenes - pharmacology | Depression - drug therapy | Muscle, Smooth - drug effects | Propranolol - pharmacology | Piperidines - pharmacology | Phloroglucinol - pharmacology | Depression - complications | Female | Antidepressive Agents - pharmacology | Tetrodotoxin - pharmacology | Haloperidol - pharmacology | Pyrazoles - pharmacology | Perylene - analogs & derivatives | Urinary Incontinence - complications | Quercetin - analogs & derivatives | Bridged Bicyclo Compounds - pharmacology | Acetylcholine - pharmacology | Rats | Atropine - pharmacology | Capsaicin - analogs & derivatives | Phentolamine - pharmacology | Verapamil - pharmacology | Adenosine Triphosphate - analogs & derivatives | Perylene - pharmacology | Urinary Incontinence - drug therapy | Animals | Quercetin - pharmacology | Muscle Contraction - drug effects | Naloxone - pharmacology | Urinary Bladder - drug effects | Kaempferols - pharmacology | Phloroglucinol - analogs & derivatives | Index Medicus
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4. Full Text Up‐regulation of P‐glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P‐glycoprotein as a novel therapeutic target for Alzheimer's disease
by Abuznait, Alaa H and Cain, Courtney and Ingram, Drury and Burk, David and Kaddoumi, Amal
Journal of pharmacy and pharmacology, ISSN 0022-3573, 08/2011, Volume 63, Issue 8, pp. 1111 - 1118
clearance | P‐glycoprotein | up‐regulation | beta amyloid | Alzheimer's disease | P-glycoprotein | Beta amyloid | Clearance | Up-regulation | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Central Nervous System Agents - therapeutic use | Cell Line | Up-Regulation | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Alzheimer Disease - drug therapy | Verapamil - pharmacology | Terpenes - pharmacology | Dexamethasone - pharmacology | Staining and Labeling | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Central Nervous System Agents - pharmacology | Phloroglucinol - pharmacology | Caffeine - pharmacology | Rifampin - pharmacology | Phloroglucinol - analogs & derivatives | Estradiol - pharmacology | Pentylenetetrazole - pharmacology | Index Medicus | up-regulation
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5. Full Text Hyperforin: More than an antidepressant bioactive compound?
by Medina, Miguel A and Martínez-Poveda, Beatriz and Amores-Sánchez, María I and Quesada, Ana R
Life sciences (1973), ISSN 0024-3205, 2006, Volume 79, Issue 2, pp. 105 - 111
Hypericum perforatum L | Antidepressant | Antitumoral | Antibacterial | Antiangiogenic | St. John's wort | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Bridged Bicyclo Compounds - pharmacology | Apoptosis - drug effects | Humans | Angiogenesis Inhibitors - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Terpenes - pharmacology | Animals | Phloroglucinol - pharmacology | Anti-Bacterial Agents - pharmacology | Antidepressive Agents - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Phloroglucinol - analogs & derivatives | Hypericum - chemistry | Medicine, Herbal | Antidepressants | Antibacterial agents | Medicine, Botanic | Index Medicus
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6. Hypericum perforatum: A 'modern' herbal antidepressant - Pharmacokinetics of active ingredients
by Wurglics, Mario and Schubert-Zsilavecz, Manfred
Clinical pharmacokinetics, ISSN 0312-5963, 2006, Volume 45, Issue 5, pp. 449 - 468
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Perylene - analogs & derivatives | Bridged Bicyclo Compounds - pharmacology | Plant Extracts - pharmacology | Humans | Clinical Trials as Topic | Flavonoids - pharmacokinetics | Perylene - pharmacology | Terpenes - pharmacology | Depression - drug therapy | Animals | Terpenes - pharmacokinetics | Perylene - pharmacokinetics | Plant Extracts - pharmacokinetics | Phloroglucinol - pharmacology | Antidepressive Agents - pharmacology | Flavonoids - pharmacology | Bridged Bicyclo Compounds - pharmacokinetics | Phytotherapy | Antidepressive Agents - pharmacokinetics | Phloroglucinol - analogs & derivatives | Hypericum - chemistry | Phloroglucinol - pharmacokinetics
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7. Full Text In vivo photoprotective and anti-inflammatory effect of hyperforin is associated with high antioxidant activity in vitro and ex vivo
by Meinke, Martina C and Schanzer, Sabine and Haag, Stefan F and Casetti, Federica and Müller, Marcel L and Wölfle, Ute and Kleemann, Anke and Lademann, Juergen and Schempp, Christoph M
European journal of pharmaceutics and biopharmaceutics, ISSN 0939-6411, 06/2012, Volume 81, Issue 2, pp. 346 - 350
Hypericum perforatum | Ultraviolet erythema test | Infrared radiation | Reactive oxygen species | Electron spin resonance spectroscopy | Minimal erythema dose | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Pharmaceutical technology. Pharmaceutical industry | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Free Radical Scavengers - pharmacology | Plant Extracts - pharmacology | Humans | Middle Aged | Male | Erythema - prevention & control | Terpenes - pharmacology | Young Adult | Inflammation - drug therapy | Swine | Phloroglucinol - pharmacology | Adult | Female | Double-Blind Method | Anti-Inflammatory Agents - pharmacology | Antioxidants - pharmacology | Ultraviolet Rays - adverse effects | Animals | Terpenes - administration & dosage | Keratinocytes - drug effects | Skin - radiation effects | Phloroglucinol - administration & dosage | Antioxidants - administration & dosage | Administration, Topical | Phloroglucinol - analogs & derivatives | Skin - drug effects | Hypericum - chemistry | Antioxidants | Anti-inflammatory drugs | Nuclear radiation | Radiation | Index Medicus
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8. Full Text A Myrtus communis extract enriched in myrtucummulones and ursolic acid reduces resistance of Propionibacterium acnes biofilms to antibiotics used in acne vulgaris
by Feuillolay, Catherine and Pecastaings, Sophie and Gac, Céline Le and Fiorini-Puybaret, Christel and Luc, Joëlle and Joulia, Philippe and Roques, Christine
Phytomedicine (Stuttgart), ISSN 0944-7113, 03/2016, Volume 23, Issue 3, pp. 307 - 315
Acne vulgaris | Biofilm | Erythromycin | Propionibacterium acnes | Myrtle extract | Clindamycin | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Integrative & Complementary Medicine | Plant Sciences | Science & Technology | Biofilms - drug effects | Microbial Sensitivity Tests | Myrtus - chemistry | Triterpenes - pharmacology | Erythromycin - pharmacology | Plant Extracts - pharmacology | Phloroglucinol - pharmacology | Acne Vulgaris - drug therapy | Anti-Bacterial Agents - pharmacology | Propionibacterium acnes - drug effects | Phloroglucinol - analogs & derivatives | Clindamycin - pharmacology | Drug resistance in microorganisms | Care and treatment | Usage | Myrtle | Acne | Physiological aspects | Research | Drug therapy | Index Medicus | Medicinal Chemistry | Life Sciences | Human health and pathology | Dermatology | Pharmacology | Chemical Sciences | Pharmaceutical sciences
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9. Full Text Uliginosin B presents antinociceptive effect mediated by dopaminergic and opioid systems in mice
by Stolz, Eveline Dischkaln and Viana, Alice Fialho and Hasse, Diego Rafael and von Poser, Gilsane Lino and do Rego, Jean-Claude and Rates, Stela M.K
Progress in neuro-psychopharmacology & biological psychiatry, ISSN 0278-5846, 10/2012, Volume 39, Issue 1, pp. 80 - 87
Antinociceptive | Uliginosin B | Hypericum | Phloroglucinol | Neurosciences | Clinical Neurology | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Neurosciences & Neurology | Psychiatry | Science & Technology | Biological and medical sciences | Medical sciences | Neuropharmacology | Pharmacology. Drug treatments | Analgesics - pharmacology | Sulpiride - pharmacology | Male | Brain - metabolism | Drug Interactions | Phloroglucinol - pharmacology | Radioligand Assay - methods | Pain Measurement - statistics & numerical data | Receptors, Opioid - metabolism | Receptors, Dopamine - metabolism | Phloroglucinol - antagonists & inhibitors | Rats | Rotarod Performance Test - statistics & numerical data | Pain Measurement - drug effects | Benzazepines - pharmacology | Mice, Inbred Strains | Rats, Sprague-Dawley | Brain - drug effects | Pain Measurement - methods | Animals | Dopamine Antagonists - pharmacology | Naloxone - pharmacology | Analgesics - antagonists & inhibitors | Narcotic Antagonists - pharmacology | Mice | Phloroglucinol - analogs & derivatives | Methyl aspartate | Analysis | GABA | Liquid chromatography | Haloperidol | Gross domestic product | Dopamine receptors | Index Medicus | Brain | Pain perception | Dopamine | Naloxone | Opioid receptors | Opioids | Receptor mechanisms | monoamines | sulpiride
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