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1. Full Text Protein Tyrosine Phosphatase 1B Inhibitors: A Molecular Level Legitimate Approach for the Management of Diabetes Mellitus
by Thareja, Suresh and Aggarwal, Saurabh and Bhardwaj, T. R and Kumar, Manoj
Medicinal research reviews, ISSN 0198-6325, 05/2012, Volume 32, Issue 3, pp. 459 - 517
metabolism | insulin | diabetes | protein tyrosine phosphatase 1B (PTP 1B) | obesity | Obesity | Diabetes | Metabolism | Insulin | Protein Tyrosine Phosphatase 1B (PTP 1B) | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Catalytic Domain - drug effects | Humans | Benzofurans - pharmacology | Pyridazines - pharmacology | Biphenyl Compounds - pharmacology | Insulin Resistance - physiology | Janus Kinase 2 - metabolism | Acetophenones - pharmacology | Vanadium Compounds - pharmacology | Catechols - pharmacology | Chromones - pharmacology | Thiazolidinediones - pharmacology | Insulin Secretion | Phosphates - pharmacology | Amino Acid Sequence | Peptidomimetics - pharmacology | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors | Models, Molecular | Thiophenes - pharmacology | Naphthoquinones - pharmacology | Enzyme Inhibitors - therapeutic use | Fluorides - pharmacology | Insulin - metabolism | Animals | STAT3 Transcription Factor - drug effects | Benzoates - pharmacology | Receptor, Insulin - drug effects | Receptor, Insulin - metabolism | Signal Transduction - physiology | Thiazoles - pharmacology | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Index Medicus
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2. Full Text Sub-normothermic preservation of donor hearts for transplantation using a novel solution, Somah: A comparative pre-clinical study
by Lowalekar, Samar K., MD and Cao, Haiyan, MD, PhD and Lu, Xiu-Gui, MD and Treanor, Patrick R., CCP, LCP and Thatte, Hemant S., MSc, PhD
The Journal of heart and lung transplantation, ISSN 1053-2498, 2014, Volume 33, Issue 9, pp. 963 - 970
Surgery | 2D echo | organ edema | transplantation | ex vivo cardiac function | organ preservation solutions | in vitro cardiac animation | high energy phosphates | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Respiratory System | Transplantation | Science & Technology | Tissue Survival - physiology | Histidine - pharmacology | Temperature | Sodium Chloride - pharmacology | Organ Preservation - methods | Tissue Survival - drug effects | Mannitol - pharmacology | Disaccharides - pharmacology | Glutathione - pharmacology | Time Factors | Carnitine - pharmacology | Swine | Female | Insulin - pharmacology | Oxygen Consumption | Raffinose - pharmacology | Heart Transplantation | Glucose - pharmacology | Organ Preservation Solutions - pharmacology | Adenosine - pharmacology | Carnosine - pharmacology | Cryopreservation - methods | Lactates | Animals | Glutamates - pharmacology | Heart - drug effects | Allopurinol - pharmacology | Electrolytes - pharmacology | Clinical trials | Comparative analysis | Index Medicus
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3. Full Text Secretion of ATP from Schwann cells in response to uridine triphosphate
by Liu, Guo Jun and Werry, Eryn L and Bennett, Max R
The European journal of neuroscience, ISSN 0953-816X, 01/2005, Volume 21, Issue 1, pp. 151 - 160
purinergic receptors | exocytosis | bioluminescence | protein kinase C | Bioluminescence | Protein kinase C | Purinergic receptors | Exocytosis | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Guanosine Triphosphate - pharmacology | Nucleic Acid Synthesis Inhibitors - pharmacology | Calcium - metabolism | Adenosine Triphosphate - secretion | Brefeldin A - pharmacology | Phorbol 12,13-Dibutyrate - pharmacology | Receptors, Purinergic P2Y2 | Cytochalasin D - pharmacology | Phenanthridines - pharmacology | Type C Phospholipases - antagonists & inhibitors | Diagnostic Imaging - methods | Dose-Response Relationship, Drug | Alkaloids | Botulinum Toxins - pharmacology | Glycyrrhetinic Acid - pharmacology | Drug Interactions | Isoquinolines - pharmacology | Glyburide - pharmacology | Time Factors | Botulinum Toxins, Type A | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Sciatic Nerve - cytology | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Protein Synthesis Inhibitors - pharmacology | Pyridoxal Phosphate - analogs & derivatives | Schwann Cells - secretion | Suramin - pharmacology | Schwann Cells - drug effects | Animals, Newborn | Pyridoxal Phosphate - pharmacology | Uridine Triphosphate - pharmacology | Purinergic P2 Receptor Antagonists | Rats | Protein Kinase C - antagonists & inhibitors | Purinergic P2 Receptor Agonists | Sulfonamides - pharmacology | Microscopy, Confocal - methods | Rats, Sprague-Dawley | Immunohistochemistry - methods | Animals | Benzophenanthridines | Receptors, Purinergic P2 - metabolism | Thapsigargin - pharmacology | Furosemide - pharmacology | Index Medicus
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4. Full Text Inhibitory effects of children’s toothpastes on Streptococcus mutans, Streptococcus sanguinis and Lactobacillus acidophilus
by Evans, A and Leishman, S.J and Walsh, L.J and Seow, W.K
European archives of paediatric dentistry, ISSN 1818-6300, 04/2015, Volume 16, Issue 2, pp. 219 - 226
Children’s dentifrices | Triclosan | Sodium lauryl sulphate | Streptococcus mutans | Diphosphates - pharmacology | Sweetening Agents - pharmacology | Anti-Infective Agents, Local - pharmacology | Humans | Tin Fluorides - pharmacology | Lactobacillus acidophilus - drug effects | Sodium Fluoride - pharmacology | Streptococcus mutans - drug effects | Triclosan - pharmacology | Dentifrices - pharmacology | Fluorides - pharmacology | Surface-Active Agents - pharmacology | Xylitol - pharmacology | Streptococcus sanguis - drug effects | Toothpastes - pharmacology | Sodium Dodecyl Sulfate - pharmacology | Cariostatic Agents - pharmacology | Anti-Bacterial Agents - pharmacology | Child | Phosphates - pharmacology | Sorbitol - pharmacology | Polyethylene Glycols - pharmacology | Index Medicus | Dentistry
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5. Full Text Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: Anti-angiogenic actions possibly contributing to plaque stability
by Massaro, Marika and Zampolli, Antonella and Scoditti, Egeria and Carluccio, Maria Annunziata and Storelli, Carlo and Distante, Alessandro and De Caterina, Raffaele
Cardiovascular research, ISSN 0008-6363, 05/2010, Volume 86, Issue 2, pp. 311 - 320
Angiogenesis | Cyclooxygenase-2 | Metalloproteinases | Statins | Atherosclerosis | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Neovascularization, Physiologic - drug effects | Tetradecanoylphorbol Acetate - pharmacology | rho GTP-Binding Proteins - antagonists & inhibitors | Humans | Nitrobenzenes - pharmacology | RNA, Messenger - metabolism | Simvastatin - pharmacology | Dose-Response Relationship, Drug | Botulinum Toxins - pharmacology | Matrix Metalloproteinase 9 - metabolism | Cyclooxygenase 2 - genetics | Matrix Metalloproteinase 9 - genetics | Heptanoic Acids - pharmacology | Cyclooxygenase 2 Inhibitors - pharmacology | Down-Regulation | Cells, Cultured | Enzyme Inhibitors - pharmacology | Angiogenesis Inhibitors - pharmacology | Mevalonic Acid - metabolism | Sulfonamides - pharmacology | Polyisoprenyl Phosphates - metabolism | Atorvastatin Calcium | Pyrroles - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | ADP Ribose Transferases - pharmacology | rho GTP-Binding Proteins - metabolism | Cyclooxygenase 2 - metabolism | Endothelial Cells - enzymology | Endothelial Cells - drug effects | Index Medicus
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6. Full Text Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy
by Barreira Da Silva, Rosa and Laird, Melissa E and Yatim, Nader and Fiette, Laurence and Ingersoll, Molly A and Albert, Matthew L
Nature immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 8, pp. 850 - 858
Life Sciences & Biomedicine | Immunology | Science & Technology | Dipeptidyl Peptidase 4 - metabolism | Immunotherapy - methods | Male | Adoptive Transfer | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Cell Movement - immunology | Flow Cytometry | Lymphocytes - immunology | Neoplasms, Experimental - immunology | Chemokine CXCL10 - immunology | Neoplasms, Experimental - genetics | Female | Sitagliptin Phosphate | Dipeptidyl Peptidase 4 - immunology | Chemokines - immunology | Lymphocytes - metabolism | Receptors, CXCR3 - metabolism | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Dipeptidyl Peptidase 4 - genetics | Mice, Transgenic | Mice, Knockout | Triazoles - pharmacology | Cell Movement - drug effects | Animals | Receptors, CXCR3 - immunology | Cell Line, Tumor | Chemokines - metabolism | Mice, Inbred BALB C | Pyrazines - pharmacology | Chemokine CXCL10 - metabolism | Care and treatment | Usage | Immunotherapy | Development and progression | Inflammation | Health aspects | Chemokines | Tumors | Index Medicus | Neoplasms, Experimental/genetics | Immunotherapy/methods | Cell Movement/drug effects | Neoplasms, Experimental/therapy | Lymphocytes/metabolism | Lymphocytes/immunology | Dipeptidyl Peptidase 4/genetics | Life Sciences | Chemokine CXCL10/immunology | Pyrazines/pharmacology | Dipeptidyl Peptidase 4/immunology | Dipeptidyl-Peptidase IV Inhibitors/pharmacology | Chemokines/metabolism | Receptors, CXCR3/immunology | Receptors, CXCR3/metabolism | Neoplasms, Experimental/immunology | Triazoles/pharmacology | Cell Movement/immunology | Chemokines/immunology | Dipeptidyl Peptidase 4/metabolism | Chemokine CXCL10/metabolism
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7. Full Text Zoledronate and Ion-releasing Resins Impair Dentin Collagen Degradation
by Tezvergil-Mutluay, A and Seseogullari-Dirihan, R and Feitosa, V.P and Tay, F.R and Watson, T.F and Pashley, D.H and Sauro, S
Journal of dental research, ISSN 0022-0345, 10/2014, Volume 93, Issue 10, pp. 999 - 1004
matrix metalloproteinase | bisphosphonates | calcium phosphates | phosphorylation | cathepsins | proteolysis | Life Sciences & Biomedicine | Dentistry, Oral Surgery & Medicine | Science & Technology | Resin Cements - pharmacology | Humans | Spectroscopy, Fourier Transform Infrared | Collagen - drug effects | Edetic Acid - pharmacology | Calcium Phosphates - pharmacology | Calcium Compounds - pharmacology | Cathepsins - antagonists & inhibitors | Matrix Metalloproteinases - pharmacology | Silicates - pharmacology | Tooth Demineralization - chemically induced | Solubility | Materials Testing | Imidazoles - pharmacology | Bone Density Conservation Agents - pharmacology | Calcium Sulfate - pharmacology | Matrix Metalloproteinase Inhibitors - pharmacology | Dentin - drug effects | Aluminum Compounds - pharmacology | Collagen Type I - analysis | Saliva, Artificial - chemistry | Cathepsins - pharmacology | Diphosphonates - pharmacology | Peptides - analysis | Hydrogen-Ion Concentration | Dentin | Infrared spectroscopy | Enzymes | Fourier transforms | Collagen (type I) | Cathepsins | Matrix metalloproteinase | Chemical modification | Acids | Collagen | Zoledronic acid | Resins | Acetic acid | Saliva | Edetic acid | Index Medicus | Dentistry | Research Reports
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8. Full Text Luminescence-Based Assay to Screen Preservation Solutions for Optimal Ability to Maintain Viability of Rat Intestinal Grafts
by Kasahara, N and Kikuchi, T and Doi, J and Teratani, T and Fujimoto, Y and Uemoto, S and Yasuda, Y and Kobayashi, E
Transplantation proceedings, ISSN 0041-1345, 2013, Volume 45, Issue 6, pp. 2486 - 2490
Surgery | Transplantation | Immunology | Life Sciences & Biomedicine | Science & Technology | Isotonic Solutions - pharmacology | Intestine, Small - pathology | Sodium Chloride - pharmacology | Organ Preservation - methods | Hypertonic Solutions - pharmacology | Cold Ischemia - adverse effects | Gluconates - pharmacology | Luminescent Measurements | Intestine, Small - transplantation | Mannitol - pharmacology | Luciferases - genetics | Glutathione - pharmacology | Time Factors | Adenosine Triphosphate - metabolism | Potassium Chloride - pharmacology | Phosphates - pharmacology | High-Throughput Screening Assays - methods | Cell Survival - drug effects | Insulin - pharmacology | Procaine - pharmacology | Rats, Transgenic | Tissue Culture Techniques | Raffinose - pharmacology | Rats | Spectrometry, Fluorescence | Glucose - pharmacology | Organ Preservation Solutions - pharmacology | Adenosine - pharmacology | Hydroxyethyl Starch Derivatives - pharmacology | Animals | Intestine, Small - drug effects | Allopurinol - pharmacology | Intestine, Small - metabolism | Luciferases - biosynthesis | Trehalose - pharmacology | Index Medicus
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9. Full Text Untargeted metabolomics to ascertain antibiotic modes of action
by Vincent, Isabel M and Ehmann, David E and Mills, Scott D and Perros, Manos and Barrett, Michael P
Antimicrobial agents and chemotherapy, ISSN 0066-4804, 04/2016, Volume 60, Issue 4, pp. 2281 - 2291
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Acyltransferases - antagonists & inhibitors | Metabolomics | Nucleoside-Phosphate Kinase - genetics | Ceftazidime - pharmacology | Escherichia coli - drug effects | Humans | Triclosan - metabolism | Triclosan - pharmacology | Acyltransferases - metabolism | Threonine - metabolism | Acyltransferases - genetics | Fosfomycin - metabolism | Pyrimidines - metabolism | DNA, Bacterial - antagonists & inhibitors | Ceftazidime - metabolism | Cell Wall - drug effects | Terpenes - antagonists & inhibitors | Terpenes - metabolism | Carbonyl Cyanide m-Chlorophenyl Hydrazone - pharmacology | Mass Spectrometry | Escherichia coli - metabolism | HEK293 Cells | Chromatography, Liquid | Hydroxamic Acids - pharmacology | Fosfomycin - analogs & derivatives | Carbonyl Cyanide m-Chlorophenyl Hydrazone - metabolism | Gene Expression | DNA, Bacterial - biosynthesis | Fosfomycin - pharmacology | Nucleoside-Phosphate Kinase - antagonists & inhibitors | Anti-Bacterial Agents - metabolism | Adenosine - pharmacology | Cell Wall - chemistry | Pyrimidines - pharmacology | Threonine - analogs & derivatives | Hydroxamic Acids - metabolism | Threonine - pharmacology | Metabolome - drug effects | Escherichia coli - genetics | Cell Wall - metabolism | Adenosine - metabolism | Anti-Bacterial Agents - pharmacology | Nucleoside-Phosphate Kinase - metabolism | Index Medicus
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