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Journal of allergy and clinical immunology, ISSN 0091-6749, 2016, Volume 138, Issue 1, pp. 210 - 218.e9
Background Activated phosphoinositide 3-kinase δ syndrome (APDS) 2 (p110δ-activating mutations causing senescent... 
Allergy and Immunology | and immunodeficiency | p110δ-activating mutations causing senescent T cells | hyper-IgM | adenopathy | p110δ | activated phosphoinositide 3-kinase δ syndrome | p85α | antibody deficiency | immunodeficiency | lymphadenopathy | phosphoinositide 3-kinase | Primary immunodeficiency | Class I Phosphatidylinositol 3-Kinases/genetics | RNA Splice Sites | Gene Frequency | Humans | Middle Aged | Immunologic Deficiency Syndromes/diagnosis | Child, Preschool | Genotype | Male | Young Adult | CD8-Positive T-Lymphocytes/immunology | Phenotype | T-Lymphocyte Subsets/immunology | Biopsy | Adolescent | Alleles | Adult | Female | Mutation | Child | Cohort Studies | p110 delta-activating mutations causing senescent T cells | CELLS | HUMAN IMMUNODEFICIENCY | KINASE | p85 alpha | IMMUNOLOGY | p110 delta | ALLERGY | MUTATIONS | activated phosphoinositide 3-kinase delta syndrome | T-Lymphocyte Subsets - immunology | Class I Phosphatidylinositol 3-Kinases - genetics | Immunologic Deficiency Syndromes - etiology | Immunologic Deficiency Syndromes - mortality | CD8-Positive T-Lymphocytes - metabolism | Immunologic Deficiency Syndromes - diagnosis | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - immunology | Life Sciences | Human health and pathology | Economics and Finance | Psychology | Santé publique et épidémiologie | Humanities and Social Sciences | Psychiatrics and mental health
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2016, Volume 138, Issue 6, pp. 1672 - 1680.e10
Journal Article
Nature (London), ISSN 1476-4687, 2017, Volume 542, Issue 7642, pp. 489 - 493
.... The phosphatidylinositol 3-kinase delta (PI3K delta) pathway regulates AID by suppressing its expression in B cells4... 
SUPER-ENHANCERS | INDUCED CYTIDINE DEAMINASE | DNA | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | IBRUTINIB | CLASS-SWITCH RECOMBINATION | MECHANISMS | TARGETING BTK | AID | SEQUENCING REVEALS | Isoquinolines - adverse effects | Class I Phosphatidylinositol 3-Kinases - metabolism | Humans | Lymphoma, Mantle-Cell - pathology | Phosphatidylinositol 3-Kinases - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Translocation, Genetic - drug effects | Isoquinolines - pharmacology | Antineoplastic Agents - adverse effects | Genomic Instability - drug effects | Female | Antineoplastic Agents - pharmacology | Purines - adverse effects | B-Lymphocytes - pathology | Immunoglobulin Class Switching - drug effects | Somatic Hypermutation, Immunoglobulin - drug effects | Lymphoma, Mantle-Cell - genetics | B-Lymphocytes - metabolism | Quinazolinones - pharmacology | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Enzyme Inhibitors - adverse effects | B-Lymphocytes - enzymology | Purines - pharmacology | Enzyme Inhibitors - pharmacology | Pyrimidines - pharmacology | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | B-Lymphocytes - drug effects | Animals | Agammaglobulinaemia Tyrosine Kinase | Cytidine Deaminase - metabolism | Pyrimidines - adverse effects | Cell Line, Tumor | Mice | Immunoglobulin Heavy Chains - genetics | Quinazolinones - adverse effects | Recombination, Genetic - drug effects | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article