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Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 8, pp. 937 - 948
Summary Background Tumour mutational status is an important determinant of the response of metastatic colorectal cancer to targeted treatments. However, the... 
Hematology, Oncology and Palliative Medicine | KRAS MUTATIONS | 1ST-LINE TREATMENT | LEUCOVORIN | PLUS IRINOTECAN | ONCOLOGY | RANDOMIZED PHASE-III | INHIBITS GROWTH | ACQUIRED-RESISTANCE | FLUOROURACIL | PLACEBO PLUS | TUMOR-GROWTH | Predictive Value of Tests | Proto-Oncogene Proteins p21(ras) | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Clinical Trials, Phase III as Topic | Time Factors | DNA Mutational Analysis | Colorectal Neoplasms - drug therapy | Real-Time Polymerase Chain Reaction | Precision Medicine | Receptor, TIE-1 - blood | Phosphatidylinositol 3-Kinases - blood | Genetic Predisposition to Disease | Adenocarcinoma - blood | ras Proteins - blood | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Disease Progression | Phenotype | Class I Phosphatidylinositol 3-Kinases | Biomarkers, Tumor - genetics | ras Proteins - genetics | Patient Selection | DNA, Neoplasm - blood | Female | Adenocarcinoma - genetics | Retrospective Studies | Pyridines - therapeutic use | Colorectal Neoplasms - mortality | Colorectal Neoplasms - blood | Kaplan-Meier Estimate | Proportional Hazards Models | Phenylurea Compounds - therapeutic use | Proto-Oncogene Proteins B-raf - blood | Proto-Oncogene Proteins - genetics | Treatment Outcome | Randomized Controlled Trials as Topic | Biomarkers, Tumor - blood | Phosphatidylinositol 3-Kinases - genetics | Disease-Free Survival | Proto-Oncogene Proteins B-raf - genetics | Aged | DNA, Neoplasm - genetics | Colorectal Neoplasms - pathology | Proto-Oncogene Proteins - blood | Adenocarcinoma - mortality | Medical colleges | Medical research | Cancer patients | Prognosis | Liver | DNA | Colorectal cancer | Genetic research | Medicine, Experimental | Metastasis | Life Sciences | Human health and pathology
Journal Article
Clinical Biochemistry, ISSN 0009-9120, 10/2015, Volume 48, Issue 15, pp. 993 - 998
Journal Article
Journal Article
European Urology, ISSN 0302-2838, 2016, Volume 71, Issue 6, pp. 961 - 969
Abstract Background Disease surveillance in patients with bladder cancer is important for early diagnosis of progression and metastasis and for optimised... 
Urology | Biomarker | PIK3CA | Cell-free DNA | Personalised analysis | Liquid biopsy | FGFR3 | Droplet digital polymerase chain reaction | UROTHELIAL CARCINOMA | CLONAL EVOLUTION | CIRCULATING TUMOR DNA | RADICAL CYSTECTOMY | URINE | UROLOGY & NEPHROLOGY | Class I Phosphatidylinositol 3-Kinases - urine | Predictive Value of Tests | Liquid Biopsy | Class I Phosphatidylinositol 3-Kinases - genetics | Circulating Tumor DNA - genetics | Urinary Bladder Neoplasms - blood | Humans | Middle Aged | Male | Receptor, Fibroblast Growth Factor, Type 3 - urine | Neoplasm Metastasis | Urinary Bladder Neoplasms - genetics | Time Factors | Biomarkers, Tumor - urine | DNA Mutational Analysis | Polymerase Chain Reaction | Class I Phosphatidylinositol 3-Kinases - blood | Female | Retrospective Studies | Receptor, Fibroblast Growth Factor, Type 3 - genetics | Urinary Bladder Neoplasms - urine | Genetic Predisposition to Disease | Neoplasm Invasiveness | Receptor, Fibroblast Growth Factor, Type 3 - blood | Risk Factors | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Proportional Hazards Models | Treatment Outcome | Urinary Bladder Neoplasms - surgery | Disease Progression | Biomarkers, Tumor - blood | Disease-Free Survival | Cystectomy | Phenotype | Circulating Tumor DNA - urine | Aged | Biomarkers, Tumor - genetics | Circulating Tumor DNA - blood | Mutation | Genetic aspects | Metastasis | Bladder cancer | Analysis | Genetic research | Development and progression
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2017, Volume 37, Issue 11, pp. 2075 - 2086
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 06/2012, Volume 18, Issue 12, pp. 3209 - 3211
Journal Article
Nature Communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, p. 15086
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 11/2017, Volume 23, Issue 21, pp. 6487 - 6497
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, p. e0176340
Mutation analysis of circulating tumor DNA (ctDNA) has recently been introduced as a non-invasive tumor monitoring method. In this study, we tested the mass... 
KRAS MUTATIONS | CETUXIMAB | CELLS | EVOLUTION | CIRCULATING TUMOR DNA | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | ANTI-EGFR THERAPY | BRAF | Colorectal Neoplasms - surgery | Follow-Up Studies | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Phosphatidylinositol 3-Kinases - metabolism | Feasibility Studies | Proto-Oncogene Proteins p21(ras) - blood | Sensitivity and Specificity | Polymerase Chain Reaction | Adult | Female | Adenocarcinoma - genetics | Phosphatidylinositol 3-Kinases - blood | Colorectal Neoplasms - blood | Adenocarcinoma - blood | Biomarkers - blood | Neoplasm Metastasis - genetics | Class I Phosphatidylinositol 3-Kinases | Survival Analysis | Aged | Mutation | Genotyping Techniques - methods | Longitudinal Studies | Mass Spectrometry - methods | Adenocarcinoma - surgery | Gene mutations | Colorectal cancer | Development and progression | Genetic aspects | Gene expression | Identification and classification | Health aspects | Multiplexing | Plasma | Genes | Colorectal carcinoma | Feasibility studies | Fragments | Patients | Polymerase chain reaction | Amplification | Pathology | Genotype & phenotype | Spectrometry | Sensitivity | Spectrum analysis | Deoxyribonucleic acid--DNA | Tumors | Plasmas (physics) | Cancer | Deoxyribonucleic acid | DNA
Journal Article
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 51, pp. 85349 - 85364
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2010, Volume 30, Issue 4, pp. 869 - 877
OBJECTIVE—Red wine (RW) consumption has been associated with a reduction of cardiovascular events, but limited data are available on potential mediating... 
Red wine | Nitric oxide | Endothelial function endothelial progenitor cell | REENDOTHELIALIZATION | nitric oxide | red wine | ISCHEMIA-INDUCED NEOVASCULARIZATION | ATHEROSCLEROSIS | RISK | endothelial function endothelial progenitor cell | DEFICIENT MICE | SYNTHASE | MODERATE ALCOHOL-CONSUMPTION | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | HEMATOLOGY | EXPRESSION | ARTERY-DISEASE | Tumor Necrosis Factor-alpha - metabolism | Wine | Up-Regulation | Phosphorylation | Antigens, CD34 - metabolism | Prospective Studies | Humans | Glycoproteins - metabolism | Cellular Senescence - drug effects | Ethanol - administration & dosage | Biological Availability | Male | Stilbenes - pharmacology | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Stem Cells - metabolism | Arginine - analogs & derivatives | Antigens, CD - metabolism | Beer | Flow Cytometry | Peptides - metabolism | Adult | Female | Nitric Oxide Synthase Type III - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Biomarkers - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Phosphatidylinositol 3-Kinases - blood | Endothelial Cells - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Alcoholic Beverages | Cell Adhesion - drug effects | AC133 Antigen | Nitric Oxide Synthase Type III - antagonists & inhibitors | Cell Movement - drug effects | Stem Cells - drug effects | Cell Proliferation - drug effects | Vasodilation - drug effects | Nitric Oxide - metabolism | Arginine - metabolism | Endothelial Cells - drug effects
Journal Article