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Leukemia, ISSN 1476-5551, 2018, Volume 32, Issue 9, pp. 1958 - 1969
The PI 3-kinases (PI3K) are essential mediators of chemokine receptor signaling necessary for migration of chronic lymphocytic leukemia (CLL... 
G-BETA-GAMMA | P110-GAMMA ISOFORM | ONCOLOGY | PHOSPHATIDYLINOSITOL 3-KINASE | REGULATORY SUBUNITS | CHRONIC LYMPHOCYTIC-LEUKEMIA | SURVIVAL SIGNALS | ZAP-70 EXPRESSION | HEMATOLOGY | MARROW STROMAL CELLS | T-LYMPHOCYTES | DIFFERENTIAL ROLES | Leukemia, B-Cell - metabolism | Class I Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases - metabolism | Class Ib Phosphatidylinositol 3-Kinase - genetics | Humans | Cell Survival - genetics | Lymphoma, B-Cell - genetics | Cell Movement - genetics | Gene Knockdown Techniques | CD40 Ligand - metabolism | Class Ib Phosphatidylinositol 3-Kinase - metabolism | ZAP-70 Protein-Tyrosine Kinase - metabolism | Antineoplastic Agents - pharmacology | B-Lymphocytes - pathology | Gene Expression Regulation, Neoplastic - drug effects | Mesenchymal Stem Cells - metabolism | B-Lymphocytes - metabolism | Quinazolinones - pharmacology | Cell Survival - drug effects | Cell Adhesion - genetics | Lymphoma, B-Cell - metabolism | Purines - pharmacology | Interleukin-4 - metabolism | Leukemia, B-Cell - pathology | Cell Adhesion - drug effects | Chemotaxis - genetics | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Cell Movement - drug effects | Leukemia, B-Cell - genetics | Lymphoma, B-Cell - pathology | Cytoskeleton - metabolism | Chemokines - metabolism | Class Ib Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Mutation | Immunoglobulin Heavy Chains - genetics | CXCL12 protein | Chronic lymphatic leukemia | Leukocyte migration | Leukemia | Cytology | Adhesion tests | Crosslinking | ZAP-70 protein | Lymphatic leukemia | Kinases | CD40L protein | Adhesion | Cell morphology | 1-Phosphatidylinositol 3-kinase | Cell adhesion & migration | Interleukin 4 | Inhibitors | Lymphocytes B | Actin | Morphology | Stromal cells | Inhibition | Chemokines | Cell migration
Journal Article
Nature reviews. Genetics, ISSN 1471-0064, 2006, Volume 7, Issue 8, pp. 606 - 619
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 10, p. e76405
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 29, pp. 12256 - 12266
Class IA PI3Ks are involved in the generation of the key lipid signaling molecule phosphatidylinositol 3,4,5-trisphosphate (PIP3), and inappropriate activation... 
EXCHANGE MASS-SPECTROMETRY | G-BETA-GAMMA | P110-ALPHA | PROTEIN | SPECIFICITY | RAS MUTATIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISTINCT | FUNCTIONAL-ANALYSIS | PHOSPHOLIPASE A | BINDING | Class I Phosphatidylinositol 3-Kinases - genetics | Phosphatidylinositol Phosphates - metabolism | Class I Phosphatidylinositol 3-Kinases - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Phosphatidylinositol 3-Kinases - metabolism | Spodoptera | Deuterium Exchange Measurement | Sf9 Cells | Proto-Oncogene Proteins p21(ras) - chemistry | Protein Interaction Domains and Motifs | Peptide Fragments - genetics | Second Messenger Systems | Proto-Oncogene Proteins p21(ras) - metabolism | Recombinant Proteins - metabolism | Peptide Fragments - metabolism | Mutagenesis, Site-Directed | Class I Phosphatidylinositol 3-Kinases - chemistry | Phosphatidylinositol 3-Kinases - chemistry | Models, Molecular | Recombinant Proteins - chemistry | Protein Transport | Phosphatidylinositol 3-Kinases - genetics | Point Mutation | Peptide Fragments - chemistry | Animals | Protein Conformation | Enzyme Activation | Lipid Bilayers - metabolism | Liposomes | Amino Acid Substitution | hydrogen exchange mass spectrometry | Signal Transduction | lipid–protein interaction | Ras protein | phosphatidylinositide 3-kinase (PI 3-kinase) | lipid signaling | phosphoinositide
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 12/2005, Volume 102, Issue 51, pp. 18443 - 18448
Journal Article