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Nature (London), ISSN 1476-4687, 2016, Volume 535, Issue 7610, pp. 153 - 158
.... GSDMD-NT binds to phosphatidylinositol phosphates and phosphatidylserine (restricted to the cell membrane inner leaflet) and cardiolipin... 
LISTERIA-MONOCYTOGENES | INTERLEUKIN-1-BETA | MULTIDISCIPLINARY SCIENCES | MIXED LINEAGE KINASE | PERFORIN | NLRP3 INFLAMMASOME | INTRACELLULAR BACTERIA | GRANZYMES | CASPASE-1 ACTIVATION | GRANULYSIN | CELL-DEATH | Conserved Sequence - genetics | Inflammasomes - metabolism | Phosphatidylinositol Phosphates - metabolism | Pyroptosis - drug effects | Escherichia coli - drug effects | Humans | Molecular Sequence Data | Neoplasm Proteins - pharmacology | Escherichia coli - cytology | Neoplasm Proteins - metabolism | Escherichia coli - metabolism | Protein Multimerization - genetics | Listeria monocytogenes - metabolism | Cell Membrane - metabolism | Membrane Proteins - metabolism | Listeria monocytogenes - cytology | Porosity - drug effects | Neoplasm Proteins - genetics | Cell Membrane - drug effects | Staphylococcus aureus - metabolism | Amino Acid Sequence | Cell Line | Microbial Viability - drug effects | Membrane Proteins - genetics | Mice, Inbred C57BL | Phosphatidylserines - metabolism | Neoplasm Proteins - chemistry | Cardiolipins - metabolism | Cell Membrane - ultrastructure | Protein Structure, Tertiary - genetics | Microscopy, Electron | Pyroptosis - genetics | Protein Transport | Liposomes - chemistry | Animals | Membrane Proteins - chemistry | Cell Membrane Permeability - drug effects | Staphylococcus aureus - cytology | Liposomes - metabolism | Mice | Mutation | Staphylococcus aureus - drug effects | Listeria monocytogenes - drug effects | Observations | Apoptosis | Proteins | Membranes | Bacterial infections | Immunology | Plasmids | Bacteria | Infections | Cells
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 44, pp. 18192 - 18202
Journal Article
Autophagy, ISSN 1554-8635, 2014, Volume 7, Issue 12, pp. 1448 - 1461
Canonical autophagy is positively regulated by the Beclin 1/phosphatidylinositol 3-kinase class III (PtdIns3KC3) complex that generates an essential... 
WIPI-1 | Atg18 | PtdInsP | LC3 | resveratrol | noncanonical autophagy | Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Autophagy-Related Protein 12 | Cell Line | Autophagy-Related Proteins | Small Ubiquitin-Related Modifier Proteins/metabolism | Phosphatidylinositol Phosphates/metabolism | Protein Transport/drug effects | Humans | Autophagy/drug effects | Lipids/chemistry | Green Fluorescent Proteins/metabolism | Autophagy-Related Protein 7 | Animals | Autophagy-Related Protein 5 | Membrane Proteins/metabolism | Carrier Proteins/drug effects | Wortmannin | Resveratrol | Androstadienes/pharmacology | Stilbenes/pharmacology | Mice | Recombinant Fusion Proteins/metabolism | Phagosomes/drug effects | Ubiquitin-Activating Enzymes/metabolism | Microtubule-Associated Proteins/metabolism | Noncanonical autophagy | CANCER-CELLS | PROTEIN | RAG GTPASES | BECLIN 1-INDEPENDENT AUTOPHAGY | MAMMALIAN-CELLS | CELL BIOLOGY | PHOSPHATIDYLINOSITOL 3-PHOSPHATE | DISEASE | ENDOPLASMIC-RETICULUM | EXPRESSION | Phosphatidylinositol Phosphates - metabolism | Microtubule-Associated Proteins - metabolism | Protein Transport - drug effects | Stilbenes - pharmacology | Carrier Proteins - drug effects | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | Lipids - chemistry | Phagosomes - ultrastructure | Membrane Proteins - metabolism | Phagosomes - drug effects | Green Fluorescent Proteins - metabolism | Small Ubiquitin-Related Modifier Proteins - metabolism | Phagosomes - metabolism | Ubiquitin-Activating Enzymes - metabolism | Carrier Proteins - metabolism | Androstadienes - pharmacology | Basic Research-Paper | Basic Research Paper
Journal Article
Nature cell biology, ISSN 1476-4679, 2015, Volume 17, Issue 7, pp. 893 - 906
LC3-associated phagocytosis (LAP) is a process wherein elements of autophagy conjugate LC3 to phagosomal membranes. We characterize the molecular requirements... 
NONCANONICAL AUTOPHAGY | REGULATE AUTOPHAGY | CROHN-DISEASE | INFLAMMATION | MICE | GENERATION | NADPH OXIDASE ACTIVATION | MATURATION | GENOME-WIDE ASSOCIATION | CELL-DEATH | CELL BIOLOGY | Phagosomes - microbiology | Autophagy-Related Proteins | Phosphatidylinositol Phosphates - metabolism | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Vesicular Transport Proteins - metabolism | NADPH Oxidases - metabolism | Immunoblotting | Male | Green Fluorescent Proteins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy | RNA Interference | Tumor Suppressor Proteins - genetics | Aspergillus fumigatus - physiology | NADPH Oxidases - genetics | Female | Intracellular Signaling Peptides and Proteins - genetics | Macrophages - microbiology | Cell Line | Green Fluorescent Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Mice, Inbred C57BL | Phagosomes - metabolism | Vesicular Transport Proteins - genetics | Class III Phosphatidylinositol 3-Kinases - metabolism | Mice, Transgenic | NADPH Oxidase 2 | Membrane Glycoproteins - genetics | Mice, Knockout | Host-Pathogen Interactions | Microscopy, Confocal | Macrophages - metabolism | Animals | Phagocytosis | Cellular proteins | Development and progression | Genetic aspects | Properties | Communicable diseases
Journal Article
Nature (London), ISSN 1476-4687, 2019, Volume 567, Issue 7747, pp. 262 - 266
Cyclic GMP-AMP (cGAMP) synthase (cGAS) detects infections or tissue damage by binding to microbial or self DNA in the cytoplasm(1). Upon binding DNA, cGAS... 
SYNTHASE | CYCLIC GMP-AMP | MAVS | PROTEIN | ROLES | MULTIDISCIPLINARY SCIENCES | ADAPTER | SENSOR | Nucleotides, Cyclic - metabolism | Interferons - biosynthesis | Beclin-1 - deficiency | Vesicular Transport Proteins - metabolism | Humans | Endoplasmic Reticulum - metabolism | Autophagy-Related Protein 5 - genetics | Autophagy-Related Protein-1 Homolog - metabolism | DNA Viruses - metabolism | Interferons - immunology | Autophagy | DNA Viruses - genetics | Sea Anemones | Membrane Proteins - deficiency | HEK293 Cells | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Protein-Serine-Threonine Kinases - metabolism | Phosphate-Binding Proteins | Signal Transduction | Membrane Proteins - genetics | DNA, Viral - metabolism | Class III Phosphatidylinositol 3-Kinases - metabolism | Autophagosomes - metabolism | Cytosol - virology | Protein Transport | Carrier Proteins - genetics | Animals | Autophagy-Related Protein-1 Homolog - deficiency | Carrier Proteins - metabolism | Monomeric GTP-Binding Proteins - metabolism | Autophagy-Related Protein 5 - deficiency | Autophagy-Related Protein 5 - metabolism | Beclin-1 - genetics | Golgi Apparatus - metabolism | Mice | Beclin-1 - metabolism | Autophagy-Related Protein-1 Homolog - genetics | Nucleotides, Cyclic - immunology | Evolution, Molecular | Biological research | Autophagy (Cytology) | Enzymes | Physiological aspects | Interferon | Research | Cytoplasm | Biology, Experimental
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 3/2017, Volume 54, Issue 2, pp. 1213 - 1228
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 1/2013, Volume 110, Issue 5, pp. 1726 - 1731
Journal Article