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Neuropharmacology, ISSN 0028-3908, 03/2013, Volume 66, pp. 158 - 169
Group III metabotropic glutamate (mGlu) receptors are localized in presynaptic terminals within basal ganglia (BG) circuitry that become hyperactive due to... 
Striatum | Basal ganglia | Akinesia | Rat | Lu AF21934 | l-DOPA-induced dyskinesia | Electrophysiology | HIGH-FREQUENCY STIMULATION | NEUROLOGICAL DISEASES | NEUROSCIENCES | RAT MODEL | STRIATAL SYNAPTIC PLASTICITY | MEDIATED MODULATION | SUBTHALAMIC NUCLEUS | UNILATERAL 6-HYDROXYDOPAMINE LESIONS | PHARMACOLOGY & PHARMACY | DEEP BRAIN-STIMULATION | L-DOPA-induced dyskinesia | MOLECULAR-MECHANISMS | Anilides - therapeutic use | Catalepsy - drug therapy | Synaptic Transmission - physiology | Excitatory Amino Acid Agonists - therapeutic use | Receptors, Metabotropic Glutamate - physiology | Male | Aminobutyrates - pharmacology | Anilides - pharmacokinetics | Parkinson Disease - drug therapy | Oxidopamine | Aminobutyrates - therapeutic use | Excitatory Postsynaptic Potentials - drug effects | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Haloperidol - antagonists & inhibitors | Allosteric Regulation - physiology | Dyskinesia, Drug-Induced - drug therapy | Catalepsy - chemically induced | Synaptic Transmission - drug effects | Haloperidol - pharmacology | Disease Models, Animal | Allosteric Regulation - drug effects | Aminobutyrates - agonists | Levodopa - pharmacology | Cyclohexanecarboxylic Acids - therapeutic use | Phosphinic Acids - agonists | Levodopa - therapeutic use | Phosphinic Acids - therapeutic use | Rats | Excitatory Amino Acid Agonists - pharmacology | Rats, Sprague-Dawley | Drug Synergism | Animals | Cyclohexanecarboxylic Acids - pharmacology | Levodopa - adverse effects | Phosphinic Acids - pharmacology | Anilides - pharmacology | Excitatory Amino Acid Agonists - pharmacokinetics | Cyclohexanecarboxylic Acids - pharmacokinetics | Receptors, Metabotropic Glutamate - agonists | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Physiological aspects | Phenols | Amino acids | Parkinson's disease | Glutamate | Drug therapy | 6-Hydroxydopamine | Phosphinic Acids | Excitatory Amino Acid Agonists | Allosteric Regulation | Catalepsy | Haloperidol | Aminobutyrates | Cellular Biology | Synaptic Transmission | Receptors, Metabotropic Glutamate | Parkinson Disease | Anilides | Life Sciences | Excitatory Postsynaptic Potentials | Cyclohexanecarboxylic Acids | Dyskinesia, Drug-Induced | Levodopa
Journal Article
Journal Article
Beilstein Journal of Organic Chemistry, ISSN 1860-5397, 03/2014, Volume 10, Issue 1, pp. 722 - 731
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 07/2013, Volume 78, Issue 14, pp. 6962 - 6974
Journal Article
FASEB Journal, ISSN 0892-6638, 04/2012, Volume 26, Issue 4, pp. 1682 - 1693
Metabotropic glutamate (mGlu) receptors are promising targets to treat numerous brain disorders. So far, allosteric modulators are the only subtype selective... 
Drug development | mGluR | Parkinson's disease | POSITIVE ALLOSTERIC MODULATION | SITE | ACTIVATION | ACID | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | drug development | BINDING DOMAIN | MOLECULAR DETERMINANTS | SYNAPTIC PLASTICITY | CELL BIOLOGY | PHARMACOLOGY | BIOLOGY | PARKINSONS-DISEASE | Antiparkinson Agents - pharmacology | Rats, Wistar | Humans | Male | Structure-Activity Relationship | Dose-Response Relationship, Drug | Receptors, Metabotropic Glutamate - genetics | HEK293 Cells | Antiparkinson Agents - chemistry | Synaptic Transmission - drug effects | Molecular Structure | Receptors, Metabotropic Glutamate - chemistry | Binding Sites | Recombinant Proteins - metabolism | Excitatory Amino Acid Agonists - metabolism | Mutagenesis, Site-Directed | Phosphinic Acids - chemistry | Rats | Excitatory Amino Acid Agonists - pharmacology | Recombinant Proteins - genetics | Mice, Knockout | Patch-Clamp Techniques | Animals | Phosphinic Acids - pharmacology | Phosphinic Acids - metabolism | Ligands | Mice | Receptors, Metabotropic Glutamate - agonists | Antiparkinson Agents - metabolism | Excitatory Amino Acid Agonists - chemistry | Excitatory Amino Acid Agonists | Neurons and Cognition | Neurobiology | Recombinant Proteins | Synaptic Transmission | Life Sciences | Phosphinic Acids | Psychology and behavior | Antiparkinson Agents | Receptors, Metabotropic Glutamate | Cognitive Sciences
Journal Article
European Journal of Inorganic Chemistry, ISSN 1434-1948, 09/2014, Volume 2014, Issue 26, pp. 4357 - 4368
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 10/2013, Volume 54, Issue 44, pp. 5873 - 5875
1-Hydroxy-phospholene 1-oxides ( and ) and 1-hydroxy-phospholane oxides ( and ) undergo fast and efficient esterification with a series of alcohols, at room... 
P-heterocycles | T3P reagent | Green synthesis | Phosphinic acid | Phosphinate | CHEMISTRY, ORGANIC | MICROWAVE-ASSISTED ESTERIFICATION | Anhydrides | Tetrahedrons | Oxides | Esterification | Alcohols
Journal Article
Organic Letters, ISSN 1523-7060, 04/2016, Volume 18, Issue 8, pp. 1888 - 1891
A radical based synthesis of a broad variety of protected enantiopure α-amino acids, including fluorinated derivatives, is described. The radical addition... 
REAGENT | TRIFLUOROMETHYL | ENANTIOSELECTIVE SYNTHESIS | ANALOGS | CHEMISTRY, ORGANIC | SYNTHETASE | INHIBITORS | GAMMA-GLUTAMATE | STRAIGHTFORWARD SYNTHESIS | PHOSPHINIC ACID | STRATEGIES | Amino Acids - chemistry | Sulfhydryl Compounds - chemistry | Molecular Structure | Ligation | Stereoisomerism | Halogenation | Organic chemistry | Chemical Sciences
Journal Article
Organic Letters, ISSN 1523-7060, 10/2013, Volume 15, Issue 20, pp. 5362 - 5365
Journal Article
Journal Article
Tetrahedron, ISSN 0040-4020, 11/2014, Volume 70, Issue 44, pp. 8280 - 8285
A few phosphinic acids, such as phenylphosphinic acids, 1-hydroxy-3-phospholene 1-oxides and 1-hydroxyphospholane oxides are esterified with simple alcohols in... 
Phosphinic amide | T3P® reagent | Green synthesis | P-Heterocycles | Phosphinic acid | Phosphinate | T3P | reagent | 1-OXIDES | CHEMISTRY, ORGANIC | MICROWAVE-ASSISTED ESTERIFICATION | T3P (R) reagent | OXIDES | DERIVATIVES | INSIGHTS
Journal Article
Separation and Purification Technology, ISSN 1383-5866, 01/2019, Volume 209, pp. 789 - 799
Scientists have always been seeking more efficient extractants for rare earths extraction and separation, especially for heavy rare earths. In this paper, a... 
Extraction | Separation | Extractant | USTB-2 | Rare earths | ENGINEERING, CHEMICAL | NITRATE MEDIA | PERFORMANCE | IONIC LIQUID | SOLVENT-EXTRACTION | Nonferrous metals
Journal Article
Environment International, ISSN 0160-4120, 04/2016, Volume 89-90, pp. 235 - 247
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 11/2017, Volume 125, Issue 11, pp. 117001-1 - 117001-9
BACKGROUND: Perfluoroalkyl phosphinic acids (PFPiAs) have been detected in humans, wildlife, and various environmental matrices. These compounds have been used... 
PERFLUORINATED PHOSPHONIC-ACIDS | PFPIAS | HUMANS | SUBSTANCES | DISCOVERY | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | TOXICOLOGY | PERFLUOROPHOSPHONATES | PROTEINS | HALOTHANE | BINDING | EXPOSURE | Fluorocarbons - toxicity | Animals | Phosphinic Acids - toxicity | Fluorocarbons - metabolism | Phosphinic Acids - metabolism | Rats | Male | Environmental Pollutants - metabolism | Environmental Pollutants - toxicity | Rats, Sprague-Dawley | Surface active agents | Metabolites | Analysis | Phosphonates | Pesticides | Physiological aspects | Mass spectrometry | Additives | Laboratories | Phosphonic acids | Alcohol | Blood | Toxicology | Perfluoroalkyls | Wildlife | Bioaccumulation | Biotransformation | Cleavage | Fish | Phosphate esters | Pollutants | Drug dosages | Half life | Formulations | Biodegradation | Analytical chemistry | Spectroscopy | Trout | Consumer products | Mass spectroscopy | Pharmacology | Exposure | Liquid chromatography | Carboxylic acids | Surfactants | Metabolism | High-performance liquid chromatography | Gas chromatography | Perfluoro compounds | Use statistics | Pharmacokinetics | High performance liquid chromatography | Miljövetenskap | Naturvetenskap | Natural Sciences | Earth and Related Environmental Sciences | Environmental Sciences | Geovetenskap och miljövetenskap
Journal Article