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Neurology, ISSN 0028-3878, 06/2014, Volume 82, Issue 23, pp. 2085 - 2091
OBJECTIVE:To determine whether phosphodiesterase type 5 (PDE5) inhibition can alleviate exercise-induced skeletal muscle ischemia in boys with Duchenne... 
NNOS | SKELETAL-MUSCLE | PERINDOPRIL | SILDENAFIL | SARCOLEMMA | HUMANS | ANGIOTENSIN-II | DYSFUNCTION | EXERCISE | CLINICAL NEUROLOGY | MDX MOUSE MODEL | Piperazines - administration & dosage | Forearm - diagnostic imaging | Phosphodiesterase 5 Inhibitors - adverse effects | Sympathetic Nervous System - drug effects | Humans | Sulfones - adverse effects | Male | Purines - administration & dosage | Sympathetic Nervous System - physiopathology | Phosphodiesterase 5 Inhibitors - pharmacokinetics | Sulfones - pharmacology | Sildenafil Citrate | Vasoconstriction - physiology | Spectroscopy, Near-Infrared | Muscular Dystrophy, Duchenne - physiopathology | Muscle, Skeletal - drug effects | Forearm - blood supply | Ultrasonography | Purines - adverse effects | Piperazines - pharmacokinetics | Phosphodiesterase 5 Inhibitors - pharmacology | Child | Carbolines - adverse effects | Muscle, Skeletal - blood supply | Muscular Dystrophy, Duchenne - drug therapy | Purines - pharmacology | Purines - pharmacokinetics | Phosphodiesterase 5 Inhibitors - administration & dosage | Sulfones - pharmacokinetics | Carbolines - administration & dosage | Muscular Dystrophy, Duchenne - complications | Piperazines - adverse effects | Piperazines - pharmacology | Vasoconstriction - drug effects | Tadalafil | Ischemia - drug therapy | Muscle, Skeletal - physiopathology | Adolescent | Exercise - physiology | Carbolines - pharmacokinetics | Carbolines - pharmacology | Ischemia - etiology | Sulfones - administration & dosage | Index Medicus | Abridged Index Medicus | 185
Journal Article
Journal Article
CIRCULATION-HEART FAILURE, ISSN 1941-3289, 01/2011, Volume 4, Issue 1, pp. 8 - 17
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2018, Volume 379, Issue 18, pp. 1722 - 1731
Journal Article
Circulation, ISSN 0009-7322, 05/2012, Volume 125, Issue 19, pp. 2323 - 2333
Background-cGMP phosphodiesterase type 5 protein is upregulated in myocardial hypertrophy. However, it has never been ascertained whether phosphodiesterase... 
fibrosis | phosphodiesterase inhibitors heart failure | diabetes mellitus type 2 | cardiac magnetic resonance imaging | diabetic diastolic heart failure | CARDIAC & CARDIOVASCULAR SYSTEMS | PULMONARY-HYPERTENSION | ENDOTHELIAL DYSFUNCTION | SILDENAFIL CITRATE | AORTIC-STENOSIS | DIASTOLIC HEART-FAILURE | HYPERTROPHY | FLOW-MEDIATED DILATATION | NITRIC-OXIDE | VALVE-REPLACEMENT | PERIPHERAL VASCULAR DISEASE | TYPE-5 INHIBITION | Piperazines - administration & dosage | Diabetic Cardiomyopathies - drug therapy | Follow-Up Studies | Phosphodiesterase 5 Inhibitors - adverse effects | Humans | Middle Aged | Sulfones - adverse effects | Magnetic Resonance Imaging - methods | Male | Purines - administration & dosage | Torsion, Mechanical | Sildenafil Citrate | Hypertrophy, Left Ventricular - pathology | Purines - adverse effects | Cardiac Imaging Techniques - methods | Hypertrophy, Left Ventricular - drug therapy | Cyclic Nucleotide Phosphodiesterases, Type 5 - metabolism | Diabetes Mellitus, Type 2 - complications | Phosphodiesterase 5 Inhibitors - administration & dosage | Treatment Outcome | Piperazines - adverse effects | Diabetic Cardiomyopathies - pathology | Aged | Ventricular Remodeling - drug effects | Sulfones - administration & dosage | Care and treatment | Magnetic resonance imaging | Cardiomyopathy | Clinical trials | Diagnosis | Phosphodiesterases | Heart diseases | Health aspects | Methods | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
The Journal of Sexual Medicine, ISSN 1743-6095, 09/2013, Volume 10, Issue 9, pp. 2312 - 2325
Journal Article
Circulation, ISSN 0009-7322, 05/2012, Volume 125, Issue 19, pp. 2353 - 2362
Background-Pressure overload resulting from aortic stenosis causes maladaptive ventricular and vascular remodeling that can lead to pulmonary hypertension,... 
aortic valve stenosis | hypertension, pulmonary | heart failure | hemodynamics | phosphodiesterase inhibitors | MORTALITY | EUROPEAN-ASSOCIATION | CARDIAC & CARDIOVASCULAR SYSTEMS | SILDENAFIL | DIASTOLIC FUNCTION | VALVE-REPLACEMENT | PERIPHERAL VASCULAR DISEASE | INDEX | HYPERTENSION | AMERICAN-SOCIETY | SYSTOLIC HEART-FAILURE | DOPPLER-ECHOCARDIOGRAPHY | Piperazines - administration & dosage | Aortic Valve Stenosis - drug therapy | Phosphodiesterase 5 Inhibitors - adverse effects | Humans | Sulfones - adverse effects | Male | Purines - administration & dosage | Aortic Valve Stenosis - diagnostic imaging | Sildenafil Citrate | Compliance - drug effects | Ultrasonography | Aged, 80 and over | Vascular Resistance - drug effects | Female | Blood Pressure - drug effects | Purines - adverse effects | Ventricular Function, Right - drug effects | Cyclic Nucleotide Phosphodiesterases, Type 5 - metabolism | Severity of Illness Index | Ventricular Function, Left - drug effects | Aortic Valve Stenosis - physiopathology | Phosphodiesterase 5 Inhibitors - administration & dosage | Stroke Volume - drug effects | Treatment Outcome | Piperazines - adverse effects | Aged | Pulmonary Circulation - drug effects | Sulfones - administration & dosage | Hypertension | Care and treatment | Aortic valve stenosis | Causes of | Patients | Pulmonary hypertension | Risk factors | Methods | Index Medicus | Abridged Index Medicus | phosphodiesterase type 5 inhibitors | pulmonary hypertension
Journal Article
Annals of Internal Medicine, ISSN 0003-4819, 11/2012, Volume 157, Issue 10, pp. 681 - 691
Journal Article
The Journal of Sexual Medicine, ISSN 1743-6095, 08/2012, Volume 9, Issue 8, pp. 2122 - 2129
Journal Article