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Nature communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, pp. 11360 - 11360
Small Molecule Libraries - pharmacology | Epithelial Cells - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Pyrazoles - chemical synthesis | Antineoplastic Agents - chemical synthesis | Epithelial Cells - drug effects | Humans | Pancreatic Ducts - drug effects | Gene Expression Regulation, Neoplastic | Cyclic Nucleotide Phosphodiesterases, Type 6 - antagonists & inhibitors | Crystallography, X-Ray | Cyclic Nucleotide Phosphodiesterases, Type 6 - chemistry | Cyclic Nucleotide Phosphodiesterases, Type 6 - genetics | Pancreatic Ducts - pathology | Benzimidazoles - chemistry | Pancreatic Ducts - metabolism | Pyrazoles - chemistry | Proto-Oncogene Proteins p21(ras) - chemistry | Phosphodiesterase Inhibitors - chemical synthesis | Antineoplastic Agents - pharmacology | Protein Interaction Domains and Motifs | Phosphodiesterase Inhibitors - chemistry | Binding Sites | Proto-Oncogene Proteins p21(ras) - metabolism | Pyrazoles - pharmacology | Recombinant Proteins - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 6 - metabolism | Gene Expression | Protein Structure, Secondary | Signal Transduction | Phosphodiesterase Inhibitors - pharmacology | Recombinant Proteins - chemistry | Small Molecule Libraries - chemical synthesis | Epithelial Cells - pathology | Recombinant Proteins - genetics | Antineoplastic Agents - chemistry | Pyrazines - chemical synthesis | Pyrazines - chemistry | Small Molecule Libraries - chemistry | Proto-Oncogene Proteins p21(ras) - antagonists & inhibitors | Cell Line, Tumor | Protein Binding | Benzimidazoles - pharmacology | Molecular Docking Simulation | Pyrazines - pharmacology | Index Medicus
Journal Article
European journal of pharmacology, ISSN 0014-2999, 03/2006, Volume 533, Issue 1-3, pp. 110 - 117
Phosphodiesterase inhibitor | Rolipram | Chronic obstructive pulmonary disease | Roflumilast | Cilomilast | Phosphodiesterase | Asthma | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Phosphodiesterase Inhibitors - therapeutic use | Cyclic Nucleotide Phosphodiesterases, Type 4 | Nitriles - pharmacology | Cyclic Nucleotide Phosphodiesterases, Type 5 | Humans | Cyclopropanes - therapeutic use | Benzamides - therapeutic use | Aminopyridines - therapeutic use | Isoenzymes - metabolism | Anti-Inflammatory Agents - therapeutic use | Carboxylic Acids - therapeutic use | Benzamides - pharmacology | Carboxylic Acids - pharmacology | Cyclopropanes - pharmacology | 3',5'-Cyclic-AMP Phosphodiesterases - metabolism | Phosphoric Diester Hydrolases - metabolism | Anti-Inflammatory Agents - pharmacology | Asthma - enzymology | Phosphodiesterase Inhibitors - pharmacology | Clinical Trials as Topic | Asthma - drug therapy | Pulmonary Disease, Chronic Obstructive - enzymology | Animals | 3',5'-Cyclic-AMP Phosphodiesterases - antagonists & inhibitors | Aminopyridines - pharmacology | 3',5'-Cyclic-GMP Phosphodiesterases | Cyclohexanecarboxylic Acids | Cyclic Nucleotide Phosphodiesterases, Type 7 | Isoenzymes - antagonists & inhibitors | Nitriles - therapeutic use | Pulmonary Disease, Chronic Obstructive - drug therapy | Hydrolysis | Hypertension | Isoenzymes | Guanosine | Cyclic adenylic acid | Esterases | T cells | Adenylic acid | Cyclic guanylic acid | Index Medicus
Journal Article
Pulmonary pharmacology & therapeutics, ISSN 1094-5539, 2010, Volume 23, Issue 4, pp. 235 - 256
Journal Article