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BIOCHEMICAL SOCIETY TRANSACTIONS, ISSN 0300-5127, 04/2007, Volume 35, pp. 172 - 176
Journal Article
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 12/2015, Volume 468, Issue 4, pp. 752 - 757
Regulation of ATP-sensitive inwardly rectifying potassium (K-ATP) channel plays a critical role in metabolism-secretion coupling of pancreatic beta-cells.... 
TRANSLOCATION | KLOTHO | Phosphoinositide-3-kinase | Ca2+ signaling | K-ATP channel | MINE cells | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRAFFICKING | Insulin | BIOPHYSICS | PANCREATIC BETA-CELLS | SECRETION | MUTATIONS | HEALTH | VAMP2
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2015, Volume 468, Issue 4, pp. 752 - 757
Regulation of ATP-sensitive inwardly rectifying potassium (K ) channel plays a critical role in metabolism-secretion coupling of pancreatic β-cells. Released... 
MIN6 cells | Phosphoinositide-3-kinase | Ca2+ signaling | KATP channel | Insulin | VAMP2 | channel | signaling
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2011, Volume 2, Issue 10, pp. 774 - 779
Phosphoinositide-3-kinases (PI3Ks) are important oncology targets due to the deregulation of this signaling pathway in a wide variety of human cancers. Herein... 
NVP-BKM120 | phosphoinositide-3-kinase | PI3K/AKT3 pathway | TARGET | RAPAMYCIN | 3-KINASES | CHEMISTRY, MEDICINAL | PATHWAY
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2019, Volume 510, Issue 2, pp. 284 - 289
Although autophagy and phagocytosis are involved in the regulation of host inflammatory response to bacterial infection in macrophages, the underlying... 
NF-κB | Phosphoinositide-3-kinase | Macrophages | Autophagy | Phagocytosis | Staphylococcus aureus | IMMUNITY | ACTIVATION | BACTERIA | LIPOTEICHOIC ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | DELETION | NF-kappa B | BIOPHYSICS | PHOSPHATIDYLINOSITOL 3-KINASES
Journal Article
Neuroscience, ISSN 0306-4522, 5/2012, Volume 210, pp. 442 - 450
We tested the hypothesis that the phosphatidylinositol-3 kinase (PI3K/Akt) pathway mediates some of the neuroprotective effects of progesterone (PROG) after... 
growth factors | neuroprotection | progesterone | apoptosis | phosphoinositide-3-kinase | Akt pathway | ischemic stroke
Journal Article
Journal Article
Journal Article
Experimental Neurology, ISSN 0014-4886, 06/2018, Volume 304, pp. 21 - 29
Chronic cerebral hypoperfusion (CCH), a leading cause of various cerebrovascular diseases, leads to cognitive dysfunction due to neuron loss and impaired... 
Chronic cerebral hypoperfusion | Liver X receptors | Phosphoinositide-3-kinase (PI3K)/phosphorylated protein kinase B (Akt) | Neurogenesis | Neural stem cell | STEM-CELLS | ADULT NEUROGENESIS | MIDBRAIN NEUROGENESIS | NEUROSCIENCES | WHITE-MATTER LESIONS | PI3K/AKT PATHWAY | SIGNALING PATHWAY | LXR AGONISTS | CENTRAL-NERVOUS-SYSTEM | PROMOTE | BRAIN
Journal Article
Journal Article
Experimental Cell Research, ISSN 0014-4827, 08/2013, Volume 319, Issue 14, pp. 2145 - 2151
Endothelial cells produce nitric oxide (NO) by activation of constitutive nitric oxide synthase (NOS) and transcription of inducible NO synthase (iNOS). We... 
Inducible NO synthase | Spleen tyrosine kinase | Phosphoinositide-3-kinase | Tetramethylpyrazine | Endothelial cells | KAPPA-B-ALPHA | PROLIFERATION | PROTEIN-TYROSINE KINASE | NITRIC-OXIDE-SYNTHASE | CELL BIOLOGY | RESPONSES | ONCOLOGY | DEGRADATION | MICE | LIGUSTICUM-CHUANXIONG | INHIBITOR | ANGELICA-SINENSIS | Endothelium, Vascular - cytology | Human Umbilical Vein Endothelial Cells | Transcription, Genetic - drug effects | Protein-Tyrosine Kinases - metabolism | Humans | NF-kappa B - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | I-kappa B Proteins - metabolism | Stilbenes - pharmacology | Cell Nucleus - metabolism | I-kappa B Kinase - metabolism | Proteolysis | Phosphorylation - drug effects | Syk Kinase | Endothelial Cells - metabolism | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Protein Transport | Tumor Necrosis Factor-alpha - pharmacology | Nitric Oxide Synthase Type II - genetics | Signal Transduction - drug effects | Pyrazines - pharmacology | Endothelial Cells - enzymology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Endothelial Cells - drug effects | Nitric Oxide Synthase Type II - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | SPLEEN | NITRIC OXIDE | PHOSPHORYLATION | TYROSINE | GENES | TRANSCRIPTION | SIGNALS | RADIOPROTECTIVE SUBSTANCES | 60 APPLIED LIFE SCIENCES
Journal Article
浙江大学学报:B卷英文版, ISSN 1673-1581, 2010, Volume 11, Issue 8, pp. 608 - 617
Journal Article