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Intensive Care Medicine, ISSN 0342-4642, 10/2013, Volume 39, Issue 10, pp. 1683 - 1694
Parenteral lipid emulsions (LEs) are commonly rich in long-chain triglycerides derived from soybean oil (SO). SO-containing emulsions may promote systemic... 
Pediatrics | Pain Medicine | Emergency Medicine | Pneumology/Respiratory System | Medicine & Public Health | Soybean oil reducing strategies | Critically ill | Intensive / Critical Care Medicine | Alternative lipid emulsions | Anesthesiology | SURGICAL-PATIENTS | RANDOMIZED CONTROLLED-TRIAL | MEDIUM-CHAIN TRIGLYCERIDES | TOTAL PARENTERAL-NUTRITION | SOYBEAN OIL EMULSION | DOUBLE-BLIND | POLYUNSATURATED FATTY-ACIDS | CARE-UNIT PATIENTS | FISH-OIL | SEVERE ACUTE-PANCREATITIS | CRITICAL CARE MEDICINE | Lecithins - administration & dosage | Emulsions - therapeutic use | Fat Emulsions, Intravenous - adverse effects | Immune System - physiology | Emulsions - adverse effects | Humans | Oxidative Stress - physiology | Fat Emulsions, Intravenous - chemistry | Fish Oils - adverse effects | Safflower Oil - administration & dosage | Fish Oils - therapeutic use | Emulsions - administration & dosage | Parenteral Nutrition - methods | Soybean Oil - administration & dosage | Adult | Fish Oils - administration & dosage | Triglycerides - therapeutic use | Databases, Bibliographic | Plant Oils - administration & dosage | Phospholipids - therapeutic use | Triglycerides - adverse effects | Phospholipids - adverse effects | Safflower Oil - adverse effects | Intensive Care Units | Lecithins - adverse effects | Parenteral Nutrition - adverse effects | Safflower Oil - therapeutic use | Phospholipids - administration & dosage | Lecithins - therapeutic use | Treatment Outcome | Soybean Oil - therapeutic use | Inflammation - etiology | Plant Oils - therapeutic use | Plant Oils - adverse effects | Randomized Controlled Trials as Topic | Soybean Oil - adverse effects | Triglycerides - administration & dosage | Immune System - drug effects | Critical Illness - therapy | Inflammation - prevention & control | Oxidative Stress - drug effects | Fat Emulsions, Intravenous - therapeutic use | Care and treatment | Research | Health aspects | Soy oil | critically ill | alternative lipid emulsions | soybean oil reducing strategies
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 11/2015, Volume 289, Issue 1, pp. 40 - 47
Drug-induced steatohepatitis is a rare form of liver injury known to be caused by only a handful of compounds. These compounds stimulate the development of... 
Chemotherapy-associated steatohepatitis | Carnitine palmitoyltransferase-I | Mitochondrial toxicity | Drug-induced steatohepatitis | Cationic amphiphilic drugs | MITOCHONDRIAL BETA-OXIDATION | AMIODARONE | DEFICIENCY PROTECTS | FATTY-ACIDS | VALPROIC ACID | METHOTREXATE METABOLISM | LONG-CHAIN | ELECTRON-TRANSPORT CHAIN | MICROVESICULAR STEATOSIS | SERIAL LIVER BIOPSIES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Camptothecin - adverse effects | Mitochondria, Liver - pathology | Fatty Liver - pathology | Humans | Liver - metabolism | Tetracycline - adverse effects | Hepatocytes - metabolism | Fatty Liver - chemically induced | Mitochondria, Liver - drug effects | Amiodarone - adverse effects | Methotrexate - adverse effects | Animals | Liver - drug effects | Lipid Metabolism - drug effects | Tamoxifen - adverse effects | Chemical and Drug Induced Liver Injury - pathology | Valproic Acid - adverse effects | Hepatocytes - drug effects | Organoplatinum Compounds - adverse effects | Perhexiline - adverse effects | Camptothecin - analogs & derivatives | Disease Models, Animal | Enzymes | Chemotherapy | Mitochondrial DNA | Synthesis | Fatty acids | Cancer | Index Medicus | OXIDATION | TRANSCRIPTION FACTORS | CARNITINE | CITROVORUM FACTOR | MITOCHONDRIA | METHOTREXATE | PHOSPHOLIPIDS | TRIGLYCERIDES | 60 APPLIED LIFE SCIENCES | CHEMOTHERAPY | FLUOROURACILS | CARBOXYLASE | ORNITHINE | LIVER CELLS | PHOSPHOTRANSFERASES | OXIDOREDUCTASES | carnitine palmitoyltransferase-I | mitochondrial toxicity
Journal Article
ACS Nano, ISSN 1936-0851, 08/2011, Volume 5, Issue 8, pp. 6410 - 6416
Inhaled nanoparticles (NPs) must first interact with the pulmonary surfactant (PS) lining layer that covers the entire internal surface of the respiratory... 
nanoparticle | surfactant inhibition | surface tension | nanotoxicology | pulmonary surfactant | MOLECULAR-DYNAMICS | PROTEIN | PARTICLES | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | ACUTE LUNG INJURY | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | RESPONSES | IN-VITRO | ATOMIC-FORCE MICROSCOPY | FILMS | SP-A | MICE | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Humans | Adsorption - drug effects | Biophysical Phenomena - drug effects | Pulmonary Surfactants - metabolism | Nanoparticles - adverse effects | Surface Properties | Pulmonary Surfactants - chemistry | Phospholipids - metabolism | Epithelial Cells - cytology | Bronchi - cytology | Cell Survival - drug effects | Cytotoxins - adverse effects | Epithelial Cells - ultrastructure | Phospholipids - chemistry | Pulmonary Surfactant-Associated Protein C - metabolism | Durapatite - chemistry | Pulmonary Surfactant-Associated Protein B - metabolism | Pulmonary Surfactant-Associated Protein B - chemistry | Pulmonary Surfactant-Associated Protein C - chemistry | Biological Products - chemistry | Cytotoxins - chemistry | Biological Products - metabolism | Durapatite - adverse effects | Toxicity Tests | Nanoparticles | Vesicles | Drug delivery systems | Toxicity | Surface chemistry | Hydroxyapatite | Nanostructure | Inhibition | Surfactants | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2016, Volume 11, Issue 9, pp. e0162027 - e0162027
Humans are exposed to a large number of environmental chemicals in their daily life, many of which are readily detectable in blood or urine. It remains... 
UNITED-STATES | DISRUPTING CHEMICALS | DIETARY EXPOSURE | PLASMA | MULTIDISCIPLINARY SCIENCES | LIVER | TCDD | BISPHENOL-A | DANISH CHILDREN | PHTHALATE METABOLITES | PESTICIDES | Liver - pathology | Kidney - pathology | Phthalic Acids - toxicity | Humans | Body Weight - drug effects | Polychlorinated Biphenyls - blood | Male | Gene Expression Profiling | Spleen - drug effects | Metals - blood | Metals - toxicity | Environmental Pollutants - blood | Dioxins - toxicity | Kidney - metabolism | Pesticides - urine | Phthalic Acids - urine | Liver - drug effects | Environmental Pollutants - urine | Polychlorinated Biphenyls - urine | Phthalic Acids - blood | Phospholipids - blood | Metals - urine | Environmental Pollutants - toxicity | Phospholipids - urine | Spleen - pathology | Kidney - drug effects | Heterocyclic Compounds - toxicity | Liver - metabolism | Gene Expression Regulation | Metabolome | Rats | Heterocyclic Compounds - blood | Pesticides - blood | Animals | Polychlorinated Biphenyls - toxicity | Spleen - metabolism | Pesticides - toxicity | Dioxins - blood | Heterocyclic Compounds - urine | Dioxins - urine | Analysis | Explosives | Chemicals | Reproductive health | Amines | Liver | Metals | Congeners | Dioxins | Heterocyclic amines | Lipids | Thyroid gland | Blood | Blood plasma | PCB compounds | Signal transduction | Toxicology | Agrochemicals | Metabolites | Rodents | Food | Urine | Puberty | Kidneys | Pesticides | Health risks | Exposure | Histology | Metabolism | Gene expression | Studies | Disease prevention | Nutrition research | Bisphenol A | Chemistry | Diet | Polychlorinated biphenyls--PCB | Apoptosis | Index Medicus | PCB | Polychlorinated biphenyls
Journal Article
Journal Article
European heart journal, ISSN 0195-668X, 2014, Volume 35, Issue 46, pp. 3277 - 3286
Journal Article
Prostaglandins, Leukotrienes and Essential Fatty Acids, ISSN 0952-3278, 2012, Volume 88, Issue 1, pp. 139 - 146
Abstract The conversion of the plant-derived omega-3 (n-3) α-linolenic acid (ALA, 18:3n-3) to the long-chain eicosapentaenoic acid (EPA, 20:5n-3) and... 
Endocrinology & Metabolism | Advanced Basic Science | Docosahexaenoic acid (DHA) | Alpha linolenic acid (ALA) | LA:ALA ratio | Linoleic acid (LA) | RAT-LIVER | CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMANS | CELL BIOLOGY | TERM INFANTS | VISUAL-ACUITY DEVELOPMENT | PLASMA | BIOSYNTHESIS | GROWTH | ENDOCRINOLOGY & METABOLISM | FISH-OIL | EICOSAPENTAENOIC ACID | Linoleic Acid - blood | Linoleic Acid - administration & dosage | Fatty Acids, Omega-6 - blood | Rats, Wistar | alpha-Linolenic Acid - analysis | Linoleic Acid - metabolism | Weaning | Safflower Oil - chemistry | Diet, High-Fat - adverse effects | Safflower Oil - metabolism | Male | Safflower Oil - administration & dosage | Linoleic Acid - adverse effects | Fatty Acids, Essential - deficiency | Fatty Acids, Essential - blood | Phospholipids - blood | Fatty Acids, Unsaturated - analysis | Phospholipids - metabolism | Plant Oils - administration & dosage | alpha-Linolenic Acid - administration & dosage | alpha-Linolenic Acid - blood | Fatty Acids, Essential - metabolism | Safflower Oil - adverse effects | Eicosapentaenoic Acid - metabolism | Phospholipids - chemistry | Rats | Fatty Acids, Omega-6 - metabolism | Linseed Oil - chemistry | Plant Oils - adverse effects | Eicosapentaenoic Acid - blood | Fatty Acids, Unsaturated - blood | Algorithms | Animals | Docosahexaenoic Acids - blood | Fatty Acids, Omega-6 - chemistry | Sunflower Oil | Linseed Oil - metabolism | Diet, Fat-Restricted | Fatty Acids, Unsaturated - adverse effects | Plant Oils - metabolism | alpha-Linolenic Acid - metabolism | Plant Oils - chemistry | Linseed Oil - administration & dosage | Docosahexaenoic Acids - metabolism | Fatty Acids, Omega-6 - adverse effects | Fatty Acids, Unsaturated - administration & dosage | Omega-3 fatty acids | Linolenic acids
Journal Article
Journal Article