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PLoS Genetics, ISSN 1553-7390, 10/2017, Volume 13, Issue 10, pp. e1007079 - e1007079
Journal Article
Journal Article
1999, ISBN 9780123584656, 471
Gene transfer within humans has been an obstacle until about 10 years ago. At that time, it was found that viral vectors were effective carriers of 'healthy... 
Drug targeting | Liposomes | Genetic vectors | Gene therapy | DNA-ligand interactions | Other branches of medicine | Genetic transformation
eBook
Cell Metabolism, ISSN 1550-4131, 05/2012, Volume 15, Issue 5, pp. 691 - 702
Numerous studies in humans link a nonsynonymous genetic polymorphism (I148M) in adiponutrin (ADPN) to various forms of fatty liver disease and liver cirrhosis.... 
ADIPOSE TRIGLYCERIDE LIPASE | COMPARATIVE GENE IDENTIFICATION-58 | LIPID-METABOLISM | MESSENGER-RNA EXPRESSION | FATTY LIVER-DISEASE | FAMILY-MEMBERS | ENZYMES | ENDOCRINOLOGY & METABOLISM | PNPLA3 | CONGENITAL GENERALIZED LIPODYSTROPHY | CHANARIN-DORFMAN-SYNDROME | CELL BIOLOGY | 1-Acylglycerol-3-Phosphate O-Acyltransferase - genetics | Lysophospholipids - metabolism | Up-Regulation | Lipids - genetics | Humans | Cercopithecus aethiops | Acyl Coenzyme A - genetics | Male | Lipids - biosynthesis | Acyltransferases - metabolism | Acyltransferases - genetics | 1-Acylglycerol-3-Phosphate O-Acyltransferase - metabolism | Cysteine Endopeptidases - metabolism | Liver - drug effects | Lipid Metabolism - genetics | Membrane Proteins - metabolism | Dietary Sucrose - metabolism | Phospholipids - metabolism | Acyl Coenzyme A - metabolism | CHO Cells | Fatty Liver - genetics | Phosphatidic Acids - genetics | Cricetinae | Fatty Liver - metabolism | Membrane Proteins - genetics | Liver - metabolism | Models, Molecular | Phospholipids - genetics | Hep G2 Cells | Mice, Knockout | Polymorphism, Genetic | Triglycerides - metabolism | Lysophospholipids - genetics | Animals | Cysteine Endopeptidases - genetics | Mice | Phosphatidic Acids - metabolism | Triglycerides - genetics | COS Cells | Physiological aspects | Medical colleges | Disease susceptibility | Liver diseases | Liver cirrhosis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, pp. e30947 - e30947
Background: Phospholipase A (PLA) is an important group of enzymes responsible for phospholipid hydrolysis in lipid signaling. PLAs have been implicated in... 
SIGNAL-TRANSDUCTION | LIPID ACYL HYDROLASE | SHOOT GRAVITROPISM | REPRODUCTIVE DEVELOPMENT | DROUGHT STRESS | BIOLOGY | GENE FAMILY | PHOSPHATIDIC-ACID | PATATIN-RELATED PHOSPHOLIPASES | GENOME-WIDE IDENTIFICATION | GUARD-CELL | Genes, Duplicate - genetics | Conserved Sequence - genetics | Arabidopsis - enzymology | Oligonucleotide Array Sequence Analysis | Molecular Sequence Data | Gene Expression Profiling | Phospholipases A - metabolism | Phylogeny | Oryza - growth & development | Oryza - genetics | Gene Expression Regulation, Developmental | Plant Proteins - chemistry | Gene Expression Regulation, Plant | Polymerase Chain Reaction | Gene Duplication - genetics | Plant Proteins - metabolism | Multigene Family - genetics | Amino Acid Sequence | Reproducibility of Results | Stress, Physiological - genetics | Oryza - enzymology | Sequence Analysis, DNA | Amino Acid Motifs | Protein Transport | Arabidopsis - genetics | Plant Proteins - genetics | Sequence Alignment | Phospholipases A - genetics | Genes, Plant - genetics | Phospholipases A - chemistry | Chromosomes, Plant - genetics | Subcellular Fractions - enzymology | Chromosome replication | Hydrolysis | Enzymes | Genes | Digital integrated circuits | Genomics | Plant genetics | Genetic research | Genomes | Phospholipases | Profiling | Cellulose | Lipids | Plants (organisms) | Phospholipids | Kinases | Molecular weight | Proteins | Signal transduction | Low molecular weights | Reproduction (copying) | Phylogenetics | Trends | Localization | Bioinformatics | Species | Rice | Stresses | Phospholipase A1 | Wildlife conservation | Phospholipase A2 | Abiotic stress | Crops | Metabolism | Gene expression | Phospholipase A | Salinity | Phospholipase | DNA microarrays | Molecular biology | Position (location) | Index Medicus
Journal Article
Journal Article
Plant Physiology, ISSN 0032-0889, 6/2013, Volume 162, Issue 2, pp. 567 - 580
Very-long-chain fatty acids (VLCFAs) with chain lengths from 20 to 34 carbons are involved in diverse biological functions such as membrane constituents, a... 
Epicuticular wax | Plant roots | Lipids | Sphingolipids | Biosynthesis | Complementation | Plants | Waxes | BIOCHEMISTRY AND METABOLISM | Fatty acids | Plant cells | SECONDARY ALCOHOLS | ABC TRANSPORTER | COA REDUCTASE | PLANT TRANSFORMATION | BRASSICA-NAPUS | ALKANE BIOSYNTHESIS | GENE FAMILY | CONDENSING ENZYME | ACYL-COENZYME | SACCHAROMYCES-CEREVISIAE | PLANT SCIENCES | Sphingolipids - biosynthesis | Acetyltransferases - metabolism | Arabidopsis - enzymology | Endoplasmic Reticulum - metabolism | Plant Roots - genetics | Lipids - biosynthesis | Phylogeny | Acetyltransferases - genetics | Genetic Complementation Test | Plant Stems - genetics | Arabidopsis Proteins - metabolism | Plants, Genetically Modified | Gene Expression Regulation, Plant | Phospholipids - metabolism | Plant Leaves - enzymology | Acyl Coenzyme A - metabolism | Fatty Acids - metabolism | 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase - genetics | Arabidopsis Proteins - genetics | Plant Roots - metabolism | Seeds - metabolism | Endoplasmic Reticulum - genetics | Seeds - genetics | Bacterial Proteins - genetics | Waxes - metabolism | Gene Knockout Techniques | Phospholipids - genetics | Arabidopsis - metabolism | Arabidopsis - genetics | Sequence Homology, Amino Acid | Plant Leaves - genetics | Plant Stems - metabolism | Membrane Lipids - metabolism | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Mutation | 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase - metabolism | Luminescent Proteins - metabolism | Arabidopsis thaliana | Physiological aspects | Eicosanoic acid | Research | Lipid metabolism | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 06/2009, Volume 104, Issue 12, pp. 1355 - 1363
Toll-like receptor (TLR)4 recognizes microbial pathogens, such as lipopolysaccharide, and mediates lipopolysaccharide-induced proinflammatory cytokine... 
Oxidized lipoprotein | Toll-like receptor-4 | Macrophage | Oxidized cholesteryl ester | toll-like receptor-4 | CARDIAC & CARDIOVASCULAR SYSTEMS | CHOLESTERYL ESTER HYDROPEROXIDES | oxidized cholesteryl ester | LOW-DENSITY-LIPOPROTEIN | macrophage | APOLIPOPROTEIN-E | PATTERN-RECOGNITION | FOAM-CELL-FORMATION | SCAVENGER-RECEPTOR-A | APOPTOTIC CELLS | PERIPHERAL VASCULAR DISEASE | OXIDIZED PHOSPHOLIPIDS | HEMATOLOGY | E-DEFICIENT MICE | NF-KAPPA-B | oxidized lipoprotein | Cholesterol Esters - metabolism | Inflammation - pathology | Protein-Tyrosine Kinases - metabolism | Humans | Cercopithecus aethiops | rac GTP-Binding Proteins - metabolism | Pinocytosis | cdc42 GTP-Binding Protein - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Lipoproteins, LDL - genetics | MAP Kinase Signaling System | Inflammation - metabolism | Phosphorylation - genetics | Protein-Tyrosine Kinases - genetics | Mice, Mutant Strains | rac GTP-Binding Proteins - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Lipoproteins, LDL - metabolism | Cholesterol Esters - genetics | Foam Cells - pathology | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Foam Cells - metabolism | Cytoskeleton - pathology | Mitogen-Activated Protein Kinase 3 - genetics | rho GTP-Binding Proteins - genetics | Cytoskeleton - genetics | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | cdc42 GTP-Binding Protein - genetics | rho GTP-Binding Proteins - metabolism | Cytoskeleton - metabolism | Inflammation - genetics | Ligands | Mice | COS Cells | Chronic Disease | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus
Journal Article
Nature genetics, ISSN 1061-4036, 2012, Volume 44, Issue 7, pp. 797 - U231
Journal Article