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American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 08/2016, Volume 311, Issue 2, pp. E530 - E541
To better understand the role of irisin in humans, we examined the effects of irisin in human primary adipocytes and fresh human subcutaneous white adipose... 
Irisin | Thermogenesis | Human white adipose tissue | Brown adipose tissue | Adipocytes browning | Osteogenesis | Adipogenesis | Immunohistochemistry | Thermogenesis - genetics | Up-Regulation | Phosphoproteins - drug effects | Extracellular Signal-Regulated MAP Kinases - drug effects | Adipocytes, Brown - metabolism | Adipogenesis - drug effects | Humans | Middle Aged | Extracellular Signal-Regulated MAP Kinases - metabolism | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Young Adult | Adipocytes, White - drug effects | Exercise | Cell Respiration - drug effects | Adult | Female | p38 Mitogen-Activated Protein Kinases - metabolism | Adipogenesis - genetics | Real-Time Polymerase Chain Reaction | Osteogenesis - genetics | STAT3 Transcription Factor - metabolism | RNA, Messenger - drug effects | Uncoupling Protein 1 - drug effects | Fibronectins - pharmacology | Signal Transduction | Adipocytes, Brown - drug effects | Uncoupling Protein 1 - metabolism | Osteoblasts - drug effects | Osteogenesis - drug effects | Cells, Cultured | Mitochondria - metabolism | Mitochondria - drug effects | Subcutaneous Fat - cytology | Blotting, Western | Obesity - metabolism | p38 Mitogen-Activated Protein Kinases - drug effects | Cell Differentiation - drug effects | STAT3 Transcription Factor - drug effects | Adolescent | Aged | Thermogenesis - drug effects | Osteoblasts - metabolism | Adipocytes, White - metabolism | Fat cells | Growth | Physiological aspects | Bones | Physiological research | Research
Journal Article
Development (Cambridge), ISSN 0950-1991, 05/2016, Volume 143, Issue 10, pp. 1674 - 1687
Journal Article
Journal of Dental Research, ISSN 0022-0345, 4/2012, Volume 91, Issue 4, pp. 407 - 412
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2014, Volume 40, Issue 3, pp. 387 - 392
Abstract Introduction Mineral trioxide aggregate (MTA) and calcium-enriched mixture (CEM) have shown osteogenic/cementogenic/dentinogenic activities; however,... 
Endocrinology & Metabolism | Dentistry | differentiation | calcium-enriched mixture | stem cell | pulp regeneration | mineral trioxide aggregate | CEM cement | human | dental pulp capping | Biomaterials | ENRICHED MIXTURE CEMENT | TREATMENT OUTCOMES | TISSUE | PULPOTOMY | PERMANENT MOLARS | IN-VITRO | MATRIX PROTEIN-1 | DENTISTRY, ORAL SURGERY & MEDICINE | HUMAN ODONTOBLASTS | IRREVERSIBLE PULPITIS | Bone Morphogenetic Protein 2 - drug effects | Phosphoproteins - drug effects | Humans | Sialoglycoproteins - drug effects | Transforming Growth Factor beta1 - drug effects | Cell Culture Techniques | Calcium Compounds - pharmacology | Fibroblast Growth Factor 4 - drug effects | Silicates - pharmacology | Microscopy, Electron, Scanning | Bone Morphogenetic Protein 4 - drug effects | Calcification, Physiologic - drug effects | Odontogenesis - drug effects | Dentinogenesis - drug effects | Cells, Cultured | Dental Pulp - cytology | Cementogenesis - drug effects | Biocompatible Materials - pharmacology | Cell Adhesion - drug effects | Extracellular Matrix Proteins - drug effects | Cell Shape - drug effects | Oxides - pharmacology | Cytokines - drug effects | Cell Differentiation - drug effects | Stem Cells - drug effects | Root Canal Filling Materials - pharmacology | Silicate Cement - pharmacology | Aluminum Compounds - pharmacology | Cell Proliferation - drug effects | Drug Combinations | Biological products | Cytokines | Gene expression | Stem cells
Journal Article
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2014, Volume 40, Issue 5, pp. 640 - 647
Abstract Introduction Mineral trioxide aggregate (MTA) has been widely used in clinical apexification and apexogenesis. However, the effects of MTA on the stem... 
Endocrinology & Metabolism | Dentistry | dentinogenesis | odontoblast | stem cell | nuclear factor kappa B | Apical papilla | PROGENITOR CELLS | OSTEOBLAST DIFFERENTIATION | ROOT | OSTEOGENIC DIFFERENTIATION | PROLIFERATION | CALCIUM HYDROXIDE | MESSENGER-RNA | DENTISTRY, ORAL SURGERY & MEDICINE | TNF-ALPHA PROMOTES | DENTAL-PULP CELLS | IMMATURE PERMANENT TEETH | Up-Regulation | Phosphoproteins - drug effects | Calcium - metabolism | Humans | Sialoglycoproteins - drug effects | Quinoxalines - pharmacology | Young Adult | Calcium Compounds - pharmacology | Silicates - pharmacology | Tooth Apex - cytology | NF-kappa B - antagonists & inhibitors | Odontogenesis - drug effects | Dentinogenesis - drug effects | Osteogenesis - drug effects | Cells, Cultured | I-kappa B Proteins - drug effects | Imidazoles - pharmacology | Alkaline Phosphatase - drug effects | Extracellular Matrix Proteins - drug effects | Cell Shape - drug effects | Oxides - pharmacology | Core Binding Factor Alpha 1 Subunit - drug effects | Signal Transduction - drug effects | Cell Differentiation - drug effects | Adolescent | Osteocalcin - drug effects | Stem Cells - drug effects | Transcription Factor RelA - drug effects | Root Canal Filling Materials - pharmacology | Aluminum Compounds - pharmacology | Cell Proliferation - drug effects | Drug Combinations | NF-kappa B - drug effects | Medical colleges | Stem cells
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 06/2010, Volume 207, Issue 6, pp. 1247 - 1260
Journal Article
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2016, Volume 143, Issue 3, pp. 466 - 471
Abstract Objective Metformin reduces cancer incidence and improves overall survival in diabetic patients. In preclinical studies, metformin decreases... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | mTOR | Metformin | Inhibition | Endometrial cancer | Window of opportunity | RISK | PROLIFERATION | OBSTETRICS & GYNECOLOGY | DIABETIC-PATIENTS | BREAST-CANCER | TRIAL | THERAPY | ONCOLOGY | COHORT | NEOADJUVANT | Immunohistochemistry | AMP-Activated Protein Kinases - metabolism | Phosphoproteins - drug effects | Prospective Studies | Apoptosis - drug effects | Humans | Leptin - metabolism | Middle Aged | Caspase 3 - metabolism | Endometrial Neoplasms - metabolism | Endometrium - drug effects | Ki-67 Antigen - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Insulin-Like Growth Factor I - drug effects | Phosphoproteins - metabolism | AMP-Activated Protein Kinases - drug effects | Carcinoma, Endometrioid - metabolism | Mitogen-Activated Protein Kinase 3 - drug effects | Lectins - metabolism | Phosphatidylinositol 3-Kinases - drug effects | Caspase 3 - drug effects | Biomarkers, Tumor - metabolism | Adult | Female | Proto-Oncogene Proteins c-akt - metabolism | Endometrium - metabolism | Cytokines - metabolism | GPI-Linked Proteins - drug effects | Metformin - pharmacology | GPI-Linked Proteins - metabolism | Hypoglycemic Agents - pharmacology | Insulin - metabolism | Cytokines - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Lectins - drug effects | Endometrial Neoplasms - pathology | Aged | Cell Proliferation - drug effects | Endometrium - pathology | Carcinoma, Endometrioid - pathology | Insulin-Like Growth Factor I - metabolism | Ki-67 Antigen - drug effects | Proto-Oncogene Proteins c-akt - drug effects | Women | Diabetics | Analysis | Oncology, Experimental | Research | Cancer
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2008, Volume 52, Issue 19, pp. 1557 - 1563
Objectives Because of the known CYP3A4 inhibition by calcium-channel blockers (CCBs), we hypothesized that there might be a drug-drug interaction between... 
Cardiovascular | Internal Medicine | clopidogrel | calcium-channel blockers | drug–drug interaction | platelets | pharmacology | drug-drug interaction | ADVERSE CARDIOVASCULAR EVENTS | CARDIAC & CARDIOVASCULAR SYSTEMS | PLATELET-AGGREGATION | STENT THROMBOSIS | VASODILATOR-STIMULATED PHOSPHOPROTEIN | WHOLE-BLOOD | PERCUTANEOUS CORONARY INTERVENTION | LIPOPHILIC STATINS | FLOW-CYTOMETRY | VASP PHOSPHORYLATION | ACTIVE METABOLITE | Phosphoproteins - drug effects | Phosphorylation | Prospective Studies | Dihydropyridines - administration & dosage | Humans | Middle Aged | Male | Reference Values | Phosphoproteins - metabolism | Case-Control Studies | Drug Interactions | Flow Cytometry | Platelet Aggregation Inhibitors - administration & dosage | Sensitivity and Specificity | Statistics, Nonparametric | Ticlopidine - administration & dosage | Female | Microfilament Proteins - metabolism | Platelet Aggregation - drug effects | Cell Adhesion Molecules - drug effects | Coronary Stenosis - therapy | Risk Assessment | Angioplasty, Balloon, Coronary - methods | Coronary Restenosis - prevention & control | Coronary Stenosis - drug therapy | Logistic Models | Treatment Outcome | Cell Adhesion Molecules - metabolism | Ticlopidine - analogs & derivatives | Coronary Stenosis - blood | Microfilament Proteins - drug effects | Calcium Channel Blockers - administration & dosage | Aged | Transluminal angioplasty | Medical colleges | Coenzymes | Drug interactions | Vasodilators | Cytochrome P-450 | Adenosine diphosphate | Fluorescence | Coronary heart disease | Aggregation | Calcium carbide | Blood platelets | Coronary artery bypass | Cardiology | Prostanoids | Adenosine triphosphatase | Cardiac patients | Confidence intervals | Enzymes | Heart attacks | Sample size | Coronary vessels | Cardiovascular disease | Family medical history | Drug therapy | Drug dosages | Index Medicus | Abridged Index Medicus
Journal Article