X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (48355) 48355
Publication (5944) 5944
Book Review (3264) 3264
Book Chapter (315) 315
Conference Proceeding (139) 139
Newsletter (124) 124
Book / eBook (32) 32
Dissertation (18) 18
Data Set (4) 4
Journal / eJournal (4) 4
Newspaper Article (3) 3
Web Resource (3) 3
Magazine Article (2) 2
Reference (2) 2
Paper (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (46687) 46687
animals (30478) 30478
phosphoproteins - metabolism (25080) 25080
humans (23339) 23339
phosphorylation (17845) 17845
biochemistry & molecular biology (13734) 13734
mice (12022) 12022
phosphoproteins - genetics (10434) 10434
cell biology (9986) 9986
rats (8284) 8284
male (8037) 8037
signal transduction (7662) 7662
molecular sequence data (7314) 7314
phosphoprotein phosphatases - metabolism (7054) 7054
proteins (6919) 6919
amino acid sequence (6498) 6498
female (6464) 6464
cell line (6200) 6200
cells, cultured (5381) 5381
expression (5237) 5237
protein binding (5002) 5002
research (4167) 4167
activation (4116) 4116
phosphoproteins - chemistry (3713) 3713
cells (3674) 3674
phosphoproteins (3625) 3625
mutation (3478) 3478
kinetics (3411) 3411
membrane proteins - metabolism (3373) 3373
gene expression (3315) 3315
base sequence (3241) 3241
binding sites (3052) 3052
protein kinases - metabolism (2978) 2978
transfection (2969) 2969
protein (2956) 2956
physiological aspects (2863) 2863
cell line, tumor (2849) 2849
blotting, western (2847) 2847
oncology (2836) 2836
article (2817) 2817
nuclear proteins - metabolism (2804) 2804
dna-binding proteins - metabolism (2730) 2730
identification (2627) 2627
molecular weight (2624) 2624
multidisciplinary sciences (2624) 2624
apoptosis (2591) 2591
analysis (2581) 2581
enzyme activation (2493) 2493
phosphoproteins - physiology (2447) 2447
adaptor proteins, signal transducing - metabolism (2437) 2437
carrier proteins - metabolism (2421) 2421
rna, messenger - metabolism (2411) 2411
time factors (2405) 2405
neurosciences (2383) 2383
phosphoprotein phosphatases - antagonists & inhibitors (2370) 2370
enzyme inhibitors - pharmacology (2366) 2366
phosphoprotein phosphatases - genetics (2346) 2346
endocrinology & metabolism (2331) 2331
abridged index medicus (2328) 2328
transcription factors - metabolism (2308) 2308
protein-serine-threonine kinases - metabolism (2273) 2273
biophysics (2188) 2188
tumor cells, cultured (2175) 2175
immunohistochemistry (2144) 2144
gene-expression (2112) 2112
phosphoproteins - biosynthesis (2108) 2108
protein structure, tertiary (2103) 2103
binding (2099) 2099
cancer (2093) 2093
gene (2073) 2073
kinases (2051) 2051
signal transduction - physiology (2033) 2033
gene expression regulation (2012) 2012
insulin receptor substrate proteins (2006) 2006
adaptor proteins, signal transducing (1988) 1988
hela cells (1976) 1976
phosphatases (1972) 1972
rats, sprague-dawley (1961) 1961
phosphoproteins - analysis (1946) 1946
immunology (1926) 1926
tyrosine - metabolism (1922) 1922
protein-tyrosine kinases - metabolism (1916) 1916
kinase (1897) 1897
mice, inbred c57bl (1897) 1897
mice, knockout (1879) 1879
phosphorylation - drug effects (1858) 1858
genetic aspects (1836) 1836
models, biological (1810) 1810
proteins - metabolism (1792) 1792
electrophoresis, polyacrylamide gel (1783) 1783
sequence homology, amino acid (1769) 1769
transcription, genetic (1761) 1761
adult (1743) 1743
in vitro techniques (1743) 1743
in-vivo (1743) 1743
genetics & heredity (1709) 1709
research article (1705) 1705
genes (1691) 1691
signal transduction - drug effects (1690) 1690
physiology (1680) 1680
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (22) 22
Collection Dvlpm't (Acquisitions) - Vendor file (4) 4
Gerstein Science - Periodical Stacks (4) 4
Online Resources - Online (4) 4
Collection Dvlpm't (Acquisitions) - Closed Orders (2) 2
Chemistry (A D Allen) - Stacks (1) 1
UofT at Mississauga - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (47973) 47973
Chinese (233) 233
Japanese (176) 176
Russian (97) 97
French (39) 39
Polish (17) 17
Spanish (11) 11
German (7) 7
Swedish (6) 6
Italian (5) 5
Ukrainian (5) 5
Croatian (2) 2
Czech (1) 1
Dutch (1) 1
Korean (1) 1
Serbian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Cell Biology, ISSN 1465-7392, 2014, Volume 16, Issue 4, pp. 357 - 366
The YAP and TAZ mediators of the Hippo pathway ( hereafter called YAP/TAZ) promote tissue proliferation and organ growth. However, how their biological... 
ORGAN GROWTH | CHOLESTEROL | YAP/TAZ | TRANSCRIPTION | HIPPO PATHWAY | STATINS | CELL BIOLOGY | Phosphorylation - physiology | Cell Proliferation | Active Transport, Cell Nucleus - physiology | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Drosophila Proteins - metabolism | Phosphoproteins - metabolism | Sterol Regulatory Element Binding Proteins - genetics | Breast Neoplasms - metabolism | Drosophila melanogaster - metabolism | RNA Interference | Tumor Suppressor Proteins - genetics | HEK293 Cells | Trans-Activators - genetics | Female | Transcription, Genetic | Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent - metabolism | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | HCT116 Cells | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Sterol Regulatory Element Binding Proteins - metabolism | Transcription Factors - genetics | Mevalonic Acid - metabolism | Polyisoprenyl Phosphates - metabolism | Transcription Factors - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | rho GTP-Binding Proteins - metabolism | Trans-Activators - metabolism | Mice | Polyisoprenyl Phosphates - biosynthesis | Pyridines - pharmacology | RNA, Small Interfering | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Cell metabolism | Genetic research | Genetic aspects | Research | Cellular control mechanisms | Index Medicus
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 11/2016, Volume 99, Issue 5, pp. 1190 - 1198
Uveal melanoma (UM) is a rare intraocular tumor that, similar to cutaneous melanoma, originates from melanocytes. To gain insights into its genetics, we... 
OCULAR MELANOMA | CELLS | COLORECTAL-CANCER | PROTEINS DLK1 | METASTASES | GENETICS & HEREDITY | RISK | EXPRESSION | RADIATION | SF3B1 | SOMATIC MUTATIONS | Melanoma - diagnosis | Exons | Humans | Middle Aged | Male | Phosphoproteins - metabolism | Case-Control Studies | RNA Splicing Factors - metabolism | DNA Copy Number Variations | Melanoma - genetics | Melanocytes - pathology | Tumor Suppressor Proteins - genetics | Aged, 80 and over | Ubiquitin Thiolesterase - metabolism | Adult | Female | Membrane Proteins - metabolism | Eukaryotic Initiation Factor-1 - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Tumor Suppressor p53-Binding Protein 1 - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Uveal Neoplasms - genetics | Genome-Wide Association Study | Tumor Suppressor Proteins - metabolism | GTP-Binding Protein alpha Subunits - metabolism | Tumor Suppressor p53-Binding Protein 1 - genetics | Membrane Proteins - genetics | Eukaryotic Initiation Factor-1 - genetics | Ubiquitin-Protein Ligases - metabolism | GTP-Binding Protein alpha Subunits - genetics | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Ubiquitin Thiolesterase - genetics | Skin Neoplasms | Uveal Neoplasms - diagnosis | Aged | Mutation | Ubiquitin-Protein Ligases - genetics | Genetic aspects | Nucleotide sequencing | Methods | Melanoma | DNA sequencing | Metastasis | Pathogenesis | Genomics | Deoxyribonucleic acid--DNA | Index Medicus | Report
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 47, Issue 6, pp. 817 - 831
The molecular mechanisms controlling the differentiation of neural progenitors into distinct subtypes of neurons during neocortical development are unknown.... 
AREA IDENTITY | NEOCORTICAL NEURONS | CELL FATE SPECIFICATION | CEREBRAL CORTICAL DEVELOPMENT | LAYER NEURONS | CENTRAL-NERVOUS-SYSTEM | SUBCORTICAL TARGETS | ZINC-FINGER GENE | SUBVENTRICULAR ZONE | NEUROSCIENCES | ZEBRAFISH FOREBRAIN | Membrane Glycoproteins - metabolism | Embryo, Mammalian | Homeodomain Proteins - metabolism | Nerve Tissue Proteins - deficiency | S100 Proteins - genetics | POU Domain Factors - genetics | Forkhead Transcription Factors - metabolism | In Situ Hybridization - methods | Repressor Proteins - metabolism | Gene Expression Regulation, Developmental - physiology | POU Domain Factors - metabolism | Animals, Newborn | DNA-Binding Proteins - physiology | Motor Neurons - physiology | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cell Cycle Proteins - metabolism | S100 Proteins - metabolism | In Situ Nick-End Labeling - methods | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Immunohistochemistry - methods | Annexin A2 - genetics | Cell Death - physiology | Green Fluorescent Proteins - biosynthesis | Mice | Annexin A2 - metabolism | Age Factors | Phosphopyruvate Hydratase - metabolism | Cell Movement - physiology | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | Amino Acids - metabolism | Motor Neurons - cytology | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Membrane Proteins - metabolism | Bromodeoxyuridine - metabolism | Cell Differentiation - physiology | Pyramidal Tracts - physiology | Nerve Tissue Proteins - physiology | Neocortex - growth & development | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Membrane Glycoproteins - genetics | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cell Count - methods | Neocortex - cytology | Receptors, Antigen, T-Cell, alpha-beta - metabolism | Neurosciences | Neurons | Developmental biology | Stem cells | Studies | Brain | Ultrasonic imaging | Transcription factors | Hybridization | Neurogenesis | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2012, Volume 287, Issue 35, pp. 29579 - 29588
Mammalian target of rapamycin complex 2 (mTORC2) is a key activator of protein kinases that act downstream of insulin and growth factor signaling. Here we... 
TRANSCRIPTION FACTORS | DIABETES-MELLITUS | LIPID-METABOLISM | AKT/PKB | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER | MOTIF PHOSPHORYLATION | RICTOR | MICE | KINASE-B | INDUCED INSULIN-RESISTANCE | Phosphorylation - physiology | Humans | Glycogen Synthase Kinase 3 beta | GTPase-Activating Proteins - metabolism | Phosphoproteins - metabolism | Cholesterol - genetics | Proto-Oncogene Proteins c-akt - genetics | Fatty Acids - genetics | Forkhead Transcription Factors - metabolism | Insulin Resistance - physiology | Tumor Suppressor Proteins - genetics | Trans-Activators - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Insulin - genetics | Proto-Oncogene Proteins c-akt - metabolism | Fatty Acids - metabolism | Lipogenesis - physiology | Sterol Regulatory Element Binding Protein 1 - metabolism | Tumor Suppressor Proteins - metabolism | Liver - metabolism | Gene Expression Regulation - physiology | Glucose - genetics | Mice, Transgenic | Phosphoproteins - genetics | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Glycogen Synthase Kinase 3 - metabolism | Hep G2 Cells | Transcription Factors - metabolism | Insulin - metabolism | Animals | Glycogen Synthase Kinase 3 - genetics | Sterol Regulatory Element Binding Protein 1 - genetics | Adaptor Proteins, Signal Transducing - genetics | Glucose - metabolism | Trans-Activators - metabolism | Forkhead Box Protein O1 | Mice | GTPase-Activating Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Cholesterol - biosynthesis | Index Medicus | mTOR Complex (mTORC) | Liver Metabolism | mTOR Complex 2 (mTORC2) | Akt | Metabolism | Lipogenesis | Insulin | Gluconeogenesis
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 05/2012, Volume 112, Issue 9, pp. 1529 - 1537
In this study, the coordinated activation of ubiquitin-proteasome pathway (UPP), autophagy-lysosomal pathway (ALP), and mitochondrial remodeling including... 
Muscle protein degradation | Mitochondrial remodelling | Mitophagy | LC3b | MuRF1 | MAMMALIAN TARGET | mitochondrial remodelling | SPORT SCIENCES | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | muscle protein degradation | EXERCISE-INDUCED MUSCLE | COORDINATE ACTIVATION | FOXO TRANSCRIPTION FACTORS | HUMAN SKELETAL-MUSCLE | MITOCHONDRIAL FISSION | mitophagy | RESISTANCE EXERCISE | GENE-EXPRESSION | C2C12 MYOTUBES | Protein Kinases - metabolism | AMP-Activated Protein Kinases - metabolism | Phosphorylation | TOR Serine-Threonine Kinases - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Serine | Ubiquitin - metabolism | Male | Physical Endurance | Insulin - blood | Phosphoproteins - metabolism | Autophagy | Tripartite Motif Proteins | Quadriceps Muscle - enzymology | Time Factors | Forkhead Transcription Factors - metabolism | Mitochondrial Proteins - metabolism | Muscle Proteins - metabolism | Adult | Proto-Oncogene Proteins c-akt - metabolism | Quadriceps Muscle - pathology | Autophagy-Related Protein 12 | Mitochondrial Membrane Transport Proteins - metabolism | Mitochondria, Muscle - enzymology | Signal Transduction | Mitochondria, Muscle - pathology | Small Ubiquitin-Related Modifier Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | SKP Cullin F-Box Protein Ligases - metabolism | Energy Intake | GTP Phosphohydrolases - metabolism | Autophagy-Related Protein 5 | Energy Metabolism | Biopsy | Running | Proteasome Endopeptidase Complex - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Blood Glucose - metabolism | Forkhead Box Protein O3 | Proteins | Musculoskeletal system | Signal transduction | Physiology | Athletes | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 02/2012, Volume 482, Issue 7384, pp. 216 - U107
Our understanding of Alzheimer's disease pathogenesis is currently limited by difficulties in obtaining live neurons from patients and the inability to model... 
AMYLOID BETA-PROTEIN | APP | MICROTUBULE-BINDING | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DOWN-SYNDROME | MOUSE MODEL | TAU | DYSFUNCTION | FIBROBLASTS | SENILE PLAQUES | Neurons - pathology | Coculture Techniques | Humans | Middle Aged | Amyloid beta-Peptides - secretion | tau Proteins - metabolism | Male | Phosphoproteins - metabolism | Endosomes - metabolism | Synapsins - metabolism | Alzheimer Disease - pathology | Cellular Reprogramming | Protease Inhibitors - pharmacology | Amyloid beta-Protein Precursor - secretion | Proteolysis | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Aged, 80 and over | Female | Neurons - metabolism | Phosphorylation - drug effects | Neurons - drug effects | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Astrocytes - cytology | Biomarkers - metabolism | Induced Pluripotent Stem Cells - pathology | Peptide Fragments - metabolism | Cells, Cultured | Peptide Fragments - secretion | Glycogen Synthase Kinase 3 - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Models, Biological | Alzheimer Disease - metabolism | Fibroblasts - cytology | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Enzyme Activation | Messenger RNA | Synthesis | Glycogen | Stem cells | Physiological aspects | Research | Alzheimer's disease | Proteins | Phosphorylation | Neurons | Efficiency | Genomes | Mutation | Alzheimers disease | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2005, Volume 280, Issue 43, pp. 35983 - 35991
Journal Article
Cell Metabolism, ISSN 1550-4131, 11/2013, Volume 18, Issue 5, pp. 698 - 711
mRNA translation is thought to be the most energy-consuming process in the cell. Translation and energy metabolism are dysregulated in a variety of diseases... 
MAMMALIAN TARGET | RAPAMYCIN | BINDING PARTNER | SKELETAL-MUSCLE | DIFFERENTIAL TRANSLATION | PROTEIN-KINASE | ENDOCRINOLOGY & METABOLISM | GENOME-WIDE | MOTIF PHOSPHORYLATION | CELL-GROWTH | COMPLEX 2 | CELL BIOLOGY | Protein Biosynthesis | Ribosomal Protein S6 Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Mitochondrial Turnover | Adenosine Triphosphate - biosynthesis | Mechanistic Target of Rapamycin Complex 2 | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Mechanistic Target of Rapamycin Complex 1 | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | Cell Nucleus - metabolism | Cell Respiration | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Autophagy - genetics | DNA, Mitochondrial - biosynthesis | Eukaryotic Initiation Factors - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Mitochondria - metabolism | Genome, Human - genetics | Transcription Factors - metabolism | Animals | Models, Biological | Mice | Adaptor Proteins, Signal Transducing - metabolism | RNA | Physiological aspects | Biosynthesis | Mitochondrial DNA | Diabetes | Binding proteins | Heart diseases | Genetic translation | Protein binding | Index Medicus
Journal Article
Science, ISSN 0036-8075, 10/2004, Volume 306, Issue 5695, pp. 457 - 461
Obesity contributes to the development of type 2 diabetes, but the underlying mechanisms are poorly understood. Using cell culture and mouse models, we show... 
Obesity | Phosphorylation | Receptors | Quantification | Liver | Lead | Insulin resistance | Type 2 diabetes mellitus | Insulin | Research Article | Type 1 diabetes mellitus | UNFOLDED PROTEIN RESPONSE | MESSENGER-RNA | ER STRESS | JNK | MULTIDISCIPLINARY SCIENCES | KINASE | IRE1 | RESISTANCE | TRANSCRIPTION FACTOR | XBP-1 | TRANSLATIONAL CONTROL | eIF-2 Kinase - metabolism | Endoplasmic Reticulum - metabolism | Homeostasis | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Phosphoproteins - metabolism | X-Box Binding Protein 1 | DNA-Binding Proteins - metabolism | Adipose Tissue - metabolism | Insulin Receptor Substrate Proteins | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | Liver - metabolism | Cells, Cultured | Insulin Resistance | Rats | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Regulatory Factor X Transcription Factors | Obesity - metabolism | Insulin - metabolism | Animals | Mitogen-Activated Protein Kinase 8 | Tunicamycin - pharmacology | Glucose - metabolism | Mice, Obese | Receptor, Insulin - metabolism | Mice | Mice, Inbred BALB C | Transcription Factors | Mutation | Mitogen-Activated Protein Kinases - metabolism | Type 2 diabetes | Causes of | Stress (Physiology) | Research | Endoplasmic reticulum | Cell culture | Enzymes | Medical research | Diabetes | Index Medicus
Journal Article